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Items: 1 to 50 of 676

1.

Suppression of Breast Cancer Stem Cells and Tumor Growth by the RUNX1 Transcription Factor.

Hong D, Fritz AJ, Finstad KH, Fitzgerald MP, Weinheimer A, Viens AL, Ramsey J, Stein JL, Lian JB, Stein GS.

Mol Cancer Res. 2018 Aug 6. pii: molcanres.0135.2018. doi: 10.1158/1541-7786.MCR-18-0135. [Epub ahead of print]

PMID:
30082484
2.

Mitotic Gene Bookmarking: An Epigenetic Program to Maintain Normal and Cancer Phenotypes.

Zaidi SK, Nickerson JA, Imbalzano AN, Lian JB, Stein JL, Stein GS.

Mol Cancer Res. 2018 Jul 12. pii: molcanres.0415.2018. doi: 10.1158/1541-7786.MCR-18-0415. [Epub ahead of print]

PMID:
30002192
3.

Epithelial-to-mesenchymal transition and cancer stem cells contribute to breast cancer heterogeneity.

Hong D, Fritz AJ, Zaidi SK, van Wijnen AJ, Nickerson JA, Imbalzano AN, Lian JB, Stein JL, Stein GS.

J Cell Physiol. 2018 Jul 3. doi: 10.1002/jcp.26847. [Epub ahead of print] Review.

PMID:
29968906
4.

Expression of the ectodomain-releasing protease ADAM17 is directly regulated by the osteosarcoma and bone-related transcription factor RUNX2.

Araya HF, Sepulveda H, Lizama CO, Vega OA, Jerez S, Briceño PF, Thaler R, Riester SM, Antonelli M, Salazar-Onfray F, Rodríguez JP, Moreno RD, Montecino M, Charbonneau M, Dubois CM, Stein GS, van Wijnen AJ, Galindo MA.

J Cell Biochem. 2018 Jun 19. doi: 10.1002/jcb.26832. [Epub ahead of print]

PMID:
29923217
5.

Corrigendum to "Pharmacological targeting of the mammalian clock reveals a novel analgesic for osteoarthritis-induced pain" [GENE 655 (2018) 1-12].

Das V, Kc R, Li X, Varma D, Qiu S, Kroin JS, Forsyth CB, Keshavarzian A, van Wijnen AJ, Park TJ, Stein GS, O-Sullivan I, Burris TP, Im HJ.

Gene. 2018 Jun 12. pii: S0378-1119(18)30662-0. doi: 10.1016/j.gene.2018.06.013. [Epub ahead of print] No abstract available.

PMID:
29890121
6.

Nuclear organization mediates cancer-compromised genetic and epigenetic control.

Zaidi SK, Fritz AJ, Tracy KM, Gordon JA, Tye CE, Boyd J, Van Wijnen AJ, Nickerson JA, Imbalzano AN, Lian JB, Stein JL, Stein GS.

Adv Biol Regul. 2018 May 9. pii: S2212-4926(18)30078-2. doi: 10.1016/j.jbior.2018.05.001. [Epub ahead of print] Review.

PMID:
29759441
7.

Thyroid Hormone Receptor β Suppression of RUNX2 Is Mediated by Brahma-Related Gene 1-Dependent Chromatin Remodeling.

Gillis NE, Taber TH, Bolf EL, Beaudet CM, Tomczak JA, White JH, Stein JL, Stein GS, Lian JB, Frietze S, Carr FE.

Endocrinology. 2018 Jun 1;159(6):2484-2494. doi: 10.1210/en.2018-00128.

PMID:
29750276
8.

Regulation of osteogenesis by long noncoding RNAs: An epigenetic mechanism contributing to bone formation.

Tye CE, Boyd JR, Page NA, Falcone MM, Stein JL, Stein GS, Lian JB.

Connect Tissue Res. 2018 Dec;59(sup1):35-41. doi: 10.1080/03008207.2017.1412432.

PMID:
29745821
9.

Higher order genomic organization and regulatory compartmentalization for cell cycle control at the G1/S-phase transition.

Ghule PN, Seward DJ, Fritz AJ, Boyd JR, van Wijnen AJ, Lian JB, Stein JL, Stein GS.

J Cell Physiol. 2018 Oct;233(10):6406-6413. doi: 10.1002/jcp.26741. Epub 2018 May 10. Review.

PMID:
29744889
10.

Nanoparticle-based targeted cancer strategies for non-invasive prostate cancer intervention.

Farina NH, Zingiryan A, Vrolijk MA, Perrapato SD, Ades S, Stein GS, Lian JB, Landry CC.

J Cell Physiol. 2018 Sep;233(9):6408-6417. doi: 10.1002/jcp.26593. Epub 2018 Apr 16. Review.

PMID:
29663383
11.

Pharmacological targeting of the mammalian clock reveals a novel analgesic for osteoarthritis-induced pain.

Das V, Kc R, Li X, Varma D, Qiu S, Kroin JS, Forsyth CB, Keshavarzian A, van Wijnen AJ, Park TJ, Stein GS, O-Sullivan I, Burris TP, Im HJ.

Gene. 2018 May 20;655:1-12. doi: 10.1016/j.gene.2018.02.048. Epub 2018 Feb 20. Erratum in: Gene. 2018 Jun 12;:.

PMID:
29474860
12.

Mitotically-Associated lncRNA (MANCR) Affects Genomic Stability and Cell Division in Aggressive Breast Cancer.

Tracy KM, Tye CE, Ghule PN, Malaby HLH, Stumpff J, Stein JL, Stein GS, Lian JB.

Mol Cancer Res. 2018 Apr;16(4):587-598. doi: 10.1158/1541-7786.MCR-17-0548. Epub 2018 Jan 29.

PMID:
29378907
13.

Development of a predictive miRNA signature for breast cancer risk among high-risk women.

Farina NH, Ramsey JE, Cuke ME, Ahern TP, Shirley DJ, Stein JL, Stein GS, Lian JB, Wood ME.

Oncotarget. 2017 Nov 28;8(68):112170-112183. doi: 10.18632/oncotarget.22750. eCollection 2017 Dec 22.

14.

Genome-wide DNase hypersensitivity, and occupancy of RUNX2 and CTCF reveal a highly dynamic gene regulome during MC3T3 pre-osteoblast differentiation.

Tai PWL, Wu H, van Wijnen AJ, Stein GS, Stein JL, Lian JB.

PLoS One. 2017 Nov 27;12(11):e0188056. doi: 10.1371/journal.pone.0188056. eCollection 2017.

15.

Bivalent Epigenetic Control of Oncofetal Gene Expression in Cancer.

Zaidi SK, Frietze SE, Gordon JA, Heath JL, Messier T, Hong D, Boyd JR, Kang M, Imbalzano AN, Lian JB, Stein JL, Stein GS.

Mol Cell Biol. 2017 Nov 13;37(23). pii: e00352-17. doi: 10.1128/MCB.00352-17. Print 2017 Dec 1. Review.

16.

Cover Image, Volume 232, Number 12, December 2017.

Reagan MR, Lian JB, Rosen CJ, Stein GS.

J Cell Physiol. 2017 Dec;232(12):i. doi: 10.1002/jcp.25563.

PMID:
28833120
17.

tsRNA signatures in cancer.

Balatti V, Nigita G, Veneziano D, Drusco A, Stein GS, Messier TL, Farina NH, Lian JB, Tomasello L, Liu CG, Palamarchuk A, Hart JR, Bell C, Carosi M, Pescarmona E, Perracchio L, Diodoro M, Russo A, Antenucci A, Visca P, Ciardi A, Harris CC, Vogt PK, Pekarsky Y, Croce CM.

Proc Natl Acad Sci U S A. 2017 Jul 25;114(30):8071-8076. doi: 10.1073/pnas.1706908114. Epub 2017 Jul 10.

18.

An AML1-ETO/miR-29b-1 regulatory circuit modulates phenotypic properties of acute myeloid leukemia cells.

Zaidi SK, Perez AW, White ES, Lian JB, Stein JL, Stein GS.

Oncotarget. 2017 Jun 20;8(25):39994-40005. doi: 10.18632/oncotarget.18127.

19.

The BRG1 ATPase of human SWI/SNF chromatin remodeling enzymes as a driver of cancer.

Wu Q, Lian JB, Stein JL, Stein GS, Nickerson JA, Imbalzano AN.

Epigenomics. 2017 Jun;9(6):919-931. doi: 10.2217/epi-2017-0034. Epub 2017 May 19. Review.

20.

Intranuclear and higher-order chromatin organization of the major histone gene cluster in breast cancer.

Fritz AJ, Ghule PN, Boyd JR, Tye CE, Page NA, Hong D, Shirley DJ, Weinheimer AS, Barutcu AR, Gerrard DL, Frietze S, van Wijnen AJ, Zaidi SK, Imbalzano AN, Lian JB, Stein JL, Stein GS.

J Cell Physiol. 2018 Feb;233(2):1278-1290. doi: 10.1002/jcp.25996. Epub 2017 Jun 22.

PMID:
28504305
21.

Selective expression of long non-coding RNAs in a breast cancer cell progression model.

Tracy KM, Tye CE, Page NA, Fritz AJ, Stein JL, Lian JB, Stein GS.

J Cell Physiol. 2018 Feb;233(2):1291-1299. doi: 10.1002/jcp.25997. Epub 2017 Jun 15.

PMID:
28488769
22.

Combination of Carmustine and Selenite Inhibits EGFR Mediated Growth Signaling in Androgen-Independent Prostate Cancer Cells.

Thamilselvan V, Menon M, Stein GS, Valeriote F, Thamilselvan S.

J Cell Biochem. 2017 Dec;118(12):4331-4340. doi: 10.1002/jcb.26086. Epub 2017 May 25.

PMID:
28430389
23.

Runx1 stabilizes the mammary epithelial cell phenotype and prevents epithelial to mesenchymal transition.

Hong D, Messier TL, Tye CE, Dobson JR, Fritz AJ, Sikora KR, Browne G, Stein JL, Lian JB, Stein GS.

Oncotarget. 2017 Mar 14;8(11):17610-17627. doi: 10.18632/oncotarget.15381.

24.

Wnt/β-Catenin Signaling Activates Expression of the Bone-Related Transcription Factor RUNX2 in Select Human Osteosarcoma Cell Types.

Vega OA, Lucero CMJ, Araya HF, Jerez S, Tapia JC, Antonelli M, Salazar-Onfray F, Las Heras F, Thaler R, Riester SM, Stein GS, van Wijnen AJ, Galindo MA.

J Cell Biochem. 2017 Nov;118(11):3662-3674. doi: 10.1002/jcb.26011. Epub 2017 May 18.

PMID:
28370561
25.

The role of Runx2 in facilitating autophagy in metastatic breast cancer cells.

Tandon M, Othman AH, Ashok V, Stein GS, Pratap J.

J Cell Physiol. 2018 Jan;233(1):559-571. doi: 10.1002/jcp.25916. Epub 2017 May 19.

PMID:
28345763
26.

Mitotic Gene Bookmarking: An Epigenetic Mechanism for Coordination of Lineage Commitment, Cell Identity and Cell Growth.

Zaidi SK, Lian JB, van Wijnen A, Stein JL, Stein GS.

Adv Exp Med Biol. 2017;962:95-102. doi: 10.1007/978-981-10-3233-2_7. Review.

PMID:
28299653
27.

A perspective on malignancy in the marrow.

Reagan MR, Lian JB, Rosen CJ, Stein GS.

J Cell Physiol. 2017 Dec;232(12):3218-3220. doi: 10.1002/jcp.25860. Epub 2017 May 16.

PMID:
28206683
28.

Profiling of human epigenetic regulators using a semi-automated real-time qPCR platform validated by next generation sequencing.

Dudakovic A, Gluscevic M, Paradise CR, Dudakovic H, Khani F, Thaler R, Ahmed FS, Li X, Dietz AB, Stein GS, Montecino MA, Deyle DR, Westendorf JJ, van Wijnen AJ.

Gene. 2017 Apr 20;609:28-37. doi: 10.1016/j.gene.2017.01.019. Epub 2017 Jan 27.

29.

Chromatin dynamics regulate mesenchymal stem cell lineage specification and differentiation to osteogenesis.

Wu H, Gordon JA, Whitfield TW, Tai PW, van Wijnen AJ, Stein JL, Stein GS, Lian JB.

Biochim Biophys Acta. 2017 Apr;1860(4):438-449. doi: 10.1016/j.bbagrm.2017.01.003. Epub 2017 Jan 8.

30.

The connection between BRG1, CTCF and topoisomerases at TAD boundaries.

Barutcu AR, Lian JB, Stein JL, Stein GS, Imbalzano AN.

Nucleus. 2017 Mar 4;8(2):150-155. doi: 10.1080/19491034.2016.1276145. Epub 2017 Jan 6. Review.

31.

Histone H4 Methyltransferase Suv420h2 Maintains Fidelity of Osteoblast Differentiation.

Khani F, Thaler R, Paradise CR, Deyle DR, Kruijthof-de Julio M, Galindo M, Gordon JA, Stein GS, Dudakovic A, van Wijnen AJ.

J Cell Biochem. 2017 May;118(5):1262-1272. doi: 10.1002/jcb.25787. Epub 2016 Nov 30.

32.

The BRG1 chromatin remodeling enzyme links cancer cell metabolism and proliferation.

Wu Q, Madany P, Dobson JR, Schnabl JM, Sharma S, Smith TC, van Wijnen AJ, Stein JL, Lian JB, Stein GS, Muthuswami R, Imbalzano AN, Nickerson JA.

Oncotarget. 2016 Jun 21;7(25):38270-38281. doi: 10.18632/oncotarget.9505.

33.

Enhancer of Zeste Homolog 2 Inhibition Stimulates Bone Formation and Mitigates Bone Loss Caused by Ovariectomy in Skeletally Mature Mice.

Dudakovic A, Camilleri ET, Riester SM, Paradise CR, Gluscevic M, O'Toole TM, Thaler R, Evans JM, Yan H, Subramaniam M, Hawse JR, Stein GS, Montecino MA, McGee-Lawrence ME, Westendorf JJ, van Wijnen AJ.

J Biol Chem. 2016 Nov 18;291(47):24594-24606. Epub 2016 Oct 10.

34.

RUNX1 contributes to higher-order chromatin organization and gene regulation in breast cancer cells.

Barutcu AR, Hong D, Lajoie BR, McCord RP, van Wijnen AJ, Lian JB, Stein JL, Dekker J, Imbalzano AN, Stein GS.

Biochim Biophys Acta. 2016 Nov;1859(11):1389-1397. doi: 10.1016/j.bbagrm.2016.08.003. Epub 2016 Aug 9.

35.

Antagonizing miR-218-5p attenuates Wnt signaling and reduces metastatic bone disease of triple negative breast cancer cells.

Taipaleenmäki H, Farina NH, van Wijnen AJ, Stein JL, Hesse E, Stein GS, Lian JB.

Oncotarget. 2016 Nov 29;7(48):79032-79046. doi: 10.18632/oncotarget.12593.

36.

Transient RUNX1 Expression during Early Mesendodermal Differentiation of hESCs Promotes Epithelial to Mesenchymal Transition through TGFB2 Signaling.

VanOudenhove JJ, Medina R, Ghule PN, Lian JB, Stein JL, Zaidi SK, Stein GS.

Stem Cell Reports. 2016 Nov 8;7(5):884-896. doi: 10.1016/j.stemcr.2016.09.006. Epub 2016 Oct 6.

37.

A microRNA/Runx1/Runx2 network regulates prostate tumor progression from onset to adenocarcinoma in TRAMP mice.

Farina NH, Zingiryan A, Akech JA, Callahan CJ, Lu H, Stein JL, Languino LR, Stein GS, Lian JB.

Oncotarget. 2016 Oct 25;7(43):70462-70474. doi: 10.18632/oncotarget.11992.

38.

The Ultrastructural Signature of Human Embryonic Stem Cells.

Underwood JM, Becker KA, Stein GS, Nickerson JA.

J Cell Biochem. 2017 Apr;118(4):764-774. doi: 10.1002/jcb.25736. Epub 2016 Dec 29.

39.

Identifying Nuclear Matrix-Attached DNA Across the Genome.

Dobson JR, Hong D, Barutcu AR, Wu H, Imbalzano AN, Lian JB, Stein JL, van Wijnen AJ, Nickerson JA, Stein GS.

J Cell Physiol. 2017 Jun;232(6):1295-1305. doi: 10.1002/jcp.25596. Epub 2017 Jan 5.

40.

Maternal expression and early induction of histone gene transcription factor Hinfp sustains development in pre-implantation embryos.

Ghule PN, Xie RL, Colby JL, Rivera-Pérez JA, Jones SN, Lian JB, Stein JL, van Wijnen AJ, Stein GS.

Dev Biol. 2016 Nov 15;419(2):311-320. doi: 10.1016/j.ydbio.2016.09.003. Epub 2016 Sep 5.

41.

Precocious Phenotypic Transcription-Factor Expression During Early Development.

VanOudenhove JJ, Medina R, Ghule PN, Lian JB, Stein JL, Zaidi SK, Stein GS.

J Cell Biochem. 2017 May;118(5):953-958. doi: 10.1002/jcb.25723. Epub 2017 Jan 11. Review.

42.

WWOX and p53 Dysregulation Synergize to Drive the Development of Osteosarcoma.

Del Mare S, Husanie H, Iancu O, Abu-Odeh M, Evangelou K, Lovat F, Volinia S, Gordon J, Amir G, Stein J, Stein GS, Croce CM, Gorgoulis V, Lian JB, Aqeilan RI.

Cancer Res. 2016 Oct 15;76(20):6107-6117. Epub 2016 Aug 22.

43.

Unique Regulatory Mechanisms for the Human Embryonic Stem Cell Cycle.

VanOudenhove JJ, Grandy RA, Ghule PN, Lian JB, Stein JL, Zaidi SK, Stein GS.

J Cell Physiol. 2017 Jun;232(6):1254-1257. doi: 10.1002/jcp.25567. Epub 2017 Jan 31. Review.

44.

SMARCA4 regulates gene expression and higher-order chromatin structure in proliferating mammary epithelial cells.

Barutcu AR, Lajoie BR, Fritz AJ, McCord RP, Nickerson JA, van Wijnen AJ, Lian JB, Stein JL, Dekker J, Stein GS, Imbalzano AN.

Genome Res. 2016 Sep;26(9):1188-201. doi: 10.1101/gr.201624.115. Epub 2016 Jul 19.

45.

Proteomic Analysis of Exosomes and Exosome-Free Conditioned Media From Human Osteosarcoma Cell Lines Reveals Secretion of Proteins Related to Tumor Progression.

Jerez S, Araya H, Thaler R, Charlesworth MC, López-Solís R, Kalergis AM, Céspedes PF, Dudakovic A, Stein GS, van Wijnen AJ, Galindo M.

J Cell Biochem. 2017 Feb;118(2):351-360. doi: 10.1002/jcb.25642. Epub 2016 Aug 15.

PMID:
27356893
46.

Ethanol Extract of Cissus quadrangularis Enhances Osteoblast Differentiation and Mineralization of Murine Pre-Osteoblastic MC3T3-E1 Cells.

Tasadduq R, Gordon J, Al-Ghanim KA, Lian JB, Van Wijnen AJ, Stein JL, Stein GS, Shakoori AR.

J Cell Physiol. 2017 Mar;232(3):540-547. doi: 10.1002/jcp.25449. Epub 2016 Jun 15.

47.

Thyroid Hormone Receptor-β (TRβ) Mediates Runt-Related Transcription Factor 2 (Runx2) Expression in Thyroid Cancer Cells: A Novel Signaling Pathway in Thyroid Cancer.

Carr FE, Tai PW, Barnum MS, Gillis NE, Evans KG, Taber TH, White JH, Tomczak JA, Jaworski DM, Zaidi SK, Lian JB, Stein JL, Stein GS.

Endocrinology. 2016 Aug;157(8):3278-92. doi: 10.1210/en.2015-2046. Epub 2016 Jun 2.

48.

Runx2/DICER/miRNA Pathway in Regulating Osteogenesis.

Zheng L, Tu Q, Meng S, Zhang L, Yu L, Song J, Hu Y, Sui L, Zhang J, Dard M, Cheng J, Murray D, Tang Y, Lian JB, Stein GS, Chen J.

J Cell Physiol. 2017 Jan;232(1):182-91. doi: 10.1002/jcp.25406. Epub 2016 Apr 26.

49.

Oncogenic epigenetic control.

Stein GS, Messier TL, Gordon JA, Boyd JR, Tye CE, Lian JB, Stein JL.

Aging (Albany NY). 2016 Apr;8(4):565-6. doi: 10.18632/aging.100940. No abstract available.

50.

Dissection of Individual Prostate Lobes in Mouse Models of Prostate Cancer to Obtain High Quality RNA.

Zingiryan A, Farina NH, Finstad KH, Stein JL, Lian JB, Stein GS.

J Cell Physiol. 2017 Jan;232(1):14-8. doi: 10.1002/jcp.25384. Epub 2016 Apr 1. Erratum in: J Cell Physiol. 2017 Nov;232(11):3194.

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