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Items: 1 to 50 of 88

1.

Phase Transitions Drive the Formation of Vesicular Stomatitis Virus Replication Compartments.

Heinrich BS, Maliga Z, Stein DA, Hyman AA, Whelan SPJ.

MBio. 2018 Sep 4;9(5). pii: e02290-17. doi: 10.1128/mBio.02290-17.

2.

Profile of the 2016 dengue outbreak in Nepal.

Khetan RP, Stein DA, Chaudhary SK, Rauniyar R, Upadhyay BP, Gupta UP, Gupta BP.

BMC Res Notes. 2018 Jul 3;11(1):423. doi: 10.1186/s13104-018-3514-3.

3.

Epidemiological Profile and Risk Factors for Acquiring HBV and/or HCV in HIV-Infected Population Groups in Nepal.

Bhattarai M, Baniya JB, Aryal N, Shrestha B, Rauniyar R, Adhikari A, Koirala P, Oli PK, Pandit RD, Stein DA, Gupta BP.

Biomed Res Int. 2018 Jan 2;2018:9241679. doi: 10.1155/2018/9241679. eCollection 2018.

4.

Human papillomavirus genotype distribution in cervical cancer biopsies from Nepalese women.

Sah SK, González JV, Shrestha S, Adhikari A, Manandhar KD, Yadav SB, Stein DA, Gupta BP, Picconi MA.

Infect Agent Cancer. 2018 Jan 17;13:4. doi: 10.1186/s13027-018-0176-7. eCollection 2018.

5.

Systems-based analysis of RIG-I-dependent signalling identifies KHSRP as an inhibitor of RIG-I receptor activation.

Soonthornvacharin S, Rodriguez-Frandsen A, Zhou Y, Galvez F, Huffmaster NJ, Tripathi S, Balasubramaniam VR, Inoue A, de Castro E, Moulton H, Stein DA, Sánchez-Aparicio MT, De Jesus PD, Nguyen Q, König R, Krogan NJ, García-Sastre A, Yoh SM, Chanda SK.

Nat Microbiol. 2017 Mar 1;2:17022. doi: 10.1038/nmicrobiol.2017.22.

6.

Integrated safety of levodopa-carbidopa intestinal gel from prospective clinical trials.

Lang AE, Rodriguez RL, Boyd JT, Chouinard S, Zadikoff C, Espay AJ, Slevin JT, Fernandez HH, Lew MF, Stein DA, Odin P, Fung VS, Klostermann F, Fasano A, Draganov PV, Schmulewitz N, Robieson WZ, Eaton S, Chatamra K, Benesh JA, Dubow J.

Mov Disord. 2016 Apr;31(4):538-46. doi: 10.1002/mds.26485. Epub 2015 Dec 23.

7.

Meta- and Orthogonal Integration of Influenza "OMICs" Data Defines a Role for UBR4 in Virus Budding.

Tripathi S, Pohl MO, Zhou Y, Rodriguez-Frandsen A, Wang G, Stein DA, Moulton HM, DeJesus P, Che J, Mulder LC, Yángüez E, Andenmatten D, Pache L, Manicassamy B, Albrecht RA, Gonzalez MG, Nguyen Q, Brass A, Elledge S, White M, Shapira S, Hacohen N, Karlas A, Meyer TF, Shales M, Gatorano A, Johnson JR, Jang G, Johnson T, Verschueren E, Sanders D, Krogan N, Shaw M, König R, Stertz S, García-Sastre A, Chanda SK.

Cell Host Microbe. 2015 Dec 9;18(6):723-35. doi: 10.1016/j.chom.2015.11.002.

8.

Inhibition of hepatitis E virus replication by peptide-conjugated morpholino oligomers.

Nan Y, Ma Z, Kannan H, Stein DA, Iversen PI, Meng XJ, Zhang YJ.

Antiviral Res. 2015 Aug;120:134-9. doi: 10.1016/j.antiviral.2015.06.006. Epub 2015 Jun 15.

9.

Unanchored K48-linked polyubiquitin synthesized by the E3-ubiquitin ligase TRIM6 stimulates the interferon-IKKε kinase-mediated antiviral response.

Rajsbaum R, Versteeg GA, Schmid S, Maestre AM, Belicha-Villanueva A, Martínez-Romero C, Patel JR, Morrison J, Pisanelli G, Miorin L, Laurent-Rolle M, Moulton HM, Stein DA, Fernandez-Sesma A, tenOever BR, García-Sastre A.

Immunity. 2014 Jun 19;40(6):880-95. doi: 10.1016/j.immuni.2014.04.018. Epub 2014 May 29.

10.

Inhibition of dengue virus replication by a class of small-molecule compounds that antagonize dopamine receptor d4 and downstream mitogen-activated protein kinase signaling.

Smith JL, Stein DA, Shum D, Fischer MA, Radu C, Bhinder B, Djaballah H, Nelson JA, Früh K, Hirsch AJ.

J Virol. 2014 May;88(10):5533-42. doi: 10.1128/JVI.00365-14. Epub 2014 Mar 5.

11.

Flaviviruses are sensitive to inhibition of thymidine synthesis pathways.

Fischer MA, Smith JL, Shum D, Stein DA, Parkins C, Bhinder B, Radu C, Hirsch AJ, Djaballah H, Nelson JA, Früh K.

J Virol. 2013 Sep;87(17):9411-9. doi: 10.1128/JVI.00101-13. Epub 2013 Jul 3.

12.

Meniscal repair.

Laible C, Stein DA, Kiridly DN.

J Am Acad Orthop Surg. 2013 Apr;21(4):204-13. doi: 10.5435/JAAOS-21-04-204. Review.

PMID:
23545726
13.

Development of peptide-conjugated morpholino oligomers as pan-arenavirus inhibitors.

Neuman BW, Bederka LH, Stein DA, Ting JP, Moulton HM, Buchmeier MJ.

Antimicrob Agents Chemother. 2011 Oct;55(10):4631-8. doi: 10.1128/AAC.00650-11. Epub 2011 Aug 8.

14.

Inhibition of dengue virus infections in cell cultures and in AG129 mice by a small interfering RNA targeting a highly conserved sequence.

Stein DA, Perry ST, Buck MD, Oehmen CS, Fischer MA, Poore E, Smith JL, Lancaster AM, Hirsch AJ, Slifka MK, Nelson JA, Shresta S, Früh K.

J Virol. 2011 Oct;85(19):10154-66. doi: 10.1128/JVI.05298-11. Epub 2011 Jul 27.

15.

Inhibition of porcine reproductive and respiratory syndrome virus infection in piglets by a peptide-conjugated morpholino oligomer.

Opriessnig T, Patel D, Wang R, Halbur PG, Meng XJ, Stein DA, Zhang YJ.

Antiviral Res. 2011 Jul;91(1):36-42. doi: 10.1016/j.antiviral.2011.04.012. Epub 2011 Apr 30.

PMID:
21554902
16.

Reduction of herpes simplex virus type-2 replication in cell cultures and in rodent models with peptide-conjugated morpholino oligomers.

Eide K, Moerdyk-Schauwecker M, Stein DA, Bildfell R, Koelle DM, Jin L.

Antivir Ther. 2010;15(8):1141-9. doi: 10.3851/IMP1694.

PMID:
21149921
17.

Inhibition of influenza virus infection in human airway cell cultures by an antisense peptide-conjugated morpholino oligomer targeting the hemagglutinin-activating protease TMPRSS2.

Böttcher-Friebertshäuser E, Stein DA, Klenk HD, Garten W.

J Virol. 2011 Feb;85(4):1554-62. doi: 10.1128/JVI.01294-10. Epub 2010 Dec 1.

18.

High-content assay to identify inhibitors of dengue virus infection.

Shum D, Smith JL, Hirsch AJ, Bhinder B, Radu C, Stein DA, Nelson JA, Früh K, Djaballah H.

Assay Drug Dev Technol. 2010 Oct;8(5):553-70. doi: 10.1089/adt.2010.0321.

19.

Coxsackievirus B3 infection activates the unfolded protein response and induces apoptosis through downregulation of p58IPK and activation of CHOP and SREBP1.

Zhang HM, Ye X, Su Y, Yuan J, Liu Z, Stein DA, Yang D.

J Virol. 2010 Sep;84(17):8446-59. doi: 10.1128/JVI.01416-09. Epub 2010 Jun 16.

20.

Inhibition of Japanese encephalitis virus replication in cultured cells and mice by a peptide-conjugated morpholino oligomer.

Anantpadma M, Stein DA, Vrati S.

J Antimicrob Chemother. 2010 May;65(5):953-61. doi: 10.1093/jac/dkq074. Epub 2010 Mar 18.

PMID:
20299495
21.

Curing of HeLa cells persistently infected with equine arteritis virus by a peptide-conjugated morpholino oligomer.

Zhang J, Stein DA, Timoney PJ, Balasuriya UB.

Virus Res. 2010 Jun;150(1-2):138-42. doi: 10.1016/j.virusres.2010.02.013. Epub 2010 Mar 3.

PMID:
20206215
22.

Morpholino oligomer-mediated protection of porcine pulmonary alveolar macrophages from arterivirus-induced cell death.

Patel D, Stein DA, Zhang YJ.

Antivir Ther. 2009;14(7):899-909. doi: 10.3851/IMP1409. Erratum in: Antivir Ther. 2010;15(3):443.

PMID:
19918094
23.

Inhibition of HSV-1 ocular infection with morpholino oligomers targeting ICP0 and ICP27.

Moerdyk-Schauwecker M, Stein DA, Eide K, Blouch RE, Bildfell R, Iversen P, Jin L.

Antiviral Res. 2009 Nov;84(2):131-41. doi: 10.1016/j.antiviral.2009.07.020. Epub 2009 Aug 7.

PMID:
19665486
24.

Severe acute respiratory syndrome coronavirus triggers apoptosis via protein kinase R but is resistant to its antiviral activity.

Krähling V, Stein DA, Spiegel M, Weber F, Mühlberger E.

J Virol. 2009 Mar;83(5):2298-309. doi: 10.1128/JVI.01245-08. Epub 2008 Dec 24.

25.

Inhibition of measles virus infections in cell cultures by peptide-conjugated morpholino oligomers.

Sleeman K, Stein DA, Tamin A, Reddish M, Iversen PL, Rota PA.

Virus Res. 2009 Mar;140(1-2):49-56. doi: 10.1016/j.virusres.2008.10.018. Epub 2009 Jan 6.

PMID:
19059443
26.

Inhibition of RNA virus infections with peptide-conjugated morpholino oligomers.

Stein DA.

Curr Pharm Des. 2008;14(25):2619-34. Review.

PMID:
18991679
27.

Co-selection of West Nile virus nucleotides that confer resistance to an antisense oligomer while maintaining long-distance RNA/RNA base pairings.

Zhang B, Dong H, Stein DA, Shi PY.

Virology. 2008 Dec 5;382(1):98-106. doi: 10.1016/j.virol.2008.08.044. Epub 2008 Oct 7.

28.

Peroneal nerve compression secondary to an anomalous biceps femoris muscle in an adolescent athlete.

Kaplan KM, Patel A, Stein DA.

Am J Orthop (Belle Mead NJ). 2008 May;37(5):268-71.

PMID:
18587506
29.

Treatment of AG129 mice with antisense morpholino oligomers increases survival time following challenge with dengue 2 virus.

Stein DA, Huang CY, Silengo S, Amantana A, Crumley S, Blouch RE, Iversen PL, Kinney RM.

J Antimicrob Chemother. 2008 Sep;62(3):555-65. doi: 10.1093/jac/dkn221. Epub 2008 Jun 19.

PMID:
18567576
30.

Inhibition of alphavirus infection in cell culture and in mice with antisense morpholino oligomers.

Paessler S, Rijnbrand R, Stein DA, Ni H, Yun NE, Dziuba N, Borisevich V, Seregin A, Ma Y, Blouch R, Iversen PL, Zacks MA.

Virology. 2008 Jul 5;376(2):357-70. doi: 10.1016/j.virol.2008.03.032. Epub 2008 May 12.

31.

Inhibition of respiratory syncytial virus infections with morpholino oligomers in cell cultures and in mice.

Lai SH, Stein DA, Guerrero-Plata A, Liao SL, Ivanciuc T, Hong C, Iversen PL, Casola A, Garofalo RP.

Mol Ther. 2008 Jun;16(6):1120-8. doi: 10.1038/mt.2008.81. Epub 2008 Apr 29.

32.

Inhibition of influenza A H3N8 virus infections in mice by morpholino oligomers.

Lupfer C, Stein DA, Mourich DV, Tepper SE, Iversen PL, Pastey M.

Arch Virol. 2008;153(5):929-37. doi: 10.1007/s00705-008-0067-0. Epub 2008 Mar 28.

PMID:
18369525
33.

Blockade of viral interleukin-6 expression of Kaposi's sarcoma-associated herpesvirus.

Zhang YJ, Bonaparte RS, Patel D, Stein DA, Iversen PL.

Mol Cancer Ther. 2008 Mar;7(3):712-20. doi: 10.1158/1535-7163.MCT-07-2036.

34.

A morpholino oligomer targeting highly conserved internal ribosome entry site sequence is able to inhibit multiple species of picornavirus.

Stone JK, Rijnbrand R, Stein DA, Ma Y, Yang Y, Iversen PL, Andino R.

Antimicrob Agents Chemother. 2008 Jun;52(6):1970-81. doi: 10.1128/AAC.00011-08. Epub 2008 Mar 17.

35.

Morpholino oligomers targeting the PB1 and NP genes enhance the survival of mice infected with highly pathogenic influenza A H7N7 virus.

Gabriel G, Nordmann A, Stein DA, Iversen PL, Klenk HD.

J Gen Virol. 2008 Apr;89(Pt 4):939-48. doi: 10.1099/vir.0.83449-0.

PMID:
18343835
36.

West Nile virus genome cyclization and RNA replication require two pairs of long-distance RNA interactions.

Zhang B, Dong H, Stein DA, Iversen PL, Shi PY.

Virology. 2008 Mar 30;373(1):1-13. doi: 10.1016/j.virol.2008.01.016. Epub 2008 Feb 6.

37.

Cell penetrating peptide conjugates of steric block oligonucleotides.

Lebleu B, Moulton HM, Abes R, Ivanova GD, Abes S, Stein DA, Iversen PL, Arzumanov AA, Gait MJ.

Adv Drug Deliv Rev. 2008 Mar 1;60(4-5):517-29. Epub 2007 Oct 22. Review.

PMID:
18037527
38.

Nucleic acid-based inhibition of flavivirus infections.

Stein DA, Shi PY.

Front Biosci. 2008 Jan 1;13:1385-95. Review.

PMID:
17981637
39.

Peptide-conjugated morpholino oligomers inhibit porcine reproductive and respiratory syndrome virus replication.

Patel D, Opriessnig T, Stein DA, Halbur PG, Meng XJ, Iversen PL, Zhang YJ.

Antiviral Res. 2008 Feb;77(2):95-107. Epub 2007 Oct 4.

PMID:
17959259
40.

Inhibition of foot-and-mouth disease virus infections in cell cultures with antisense morpholino oligomers.

Vagnozzi A, Stein DA, Iversen PL, Rieder E.

J Virol. 2007 Nov;81(21):11669-80. Epub 2007 Aug 29.

41.

Cell-penetrating peptide-morpholino conjugates alter pre-mRNA splicing of DMD (Duchenne muscular dystrophy) and inhibit murine coronavirus replication in vivo.

Moulton HM, Fletcher S, Neuman BW, McClorey G, Stein DA, Abes S, Wilton SD, Buchmeier MJ, Lebleu B, Iversen PL.

Biochem Soc Trans. 2007 Aug;35(Pt 4):826-8. Review.

PMID:
17635157
42.

In vitro resistance selection and in vivo efficacy of morpholino oligomers against West Nile virus.

Deas TS, Bennett CJ, Jones SA, Tilgner M, Ren P, Behr MJ, Stein DA, Iversen PL, Kramer LD, Bernard KA, Shi PY.

Antimicrob Agents Chemother. 2007 Jul;51(7):2470-82. Epub 2007 May 7.

43.

Antiviral effects of antisense morpholino oligomers in murine coronavirus infection models.

Burrer R, Neuman BW, Ting JP, Stein DA, Moulton HM, Iversen PL, Kuhn P, Buchmeier MJ.

J Virol. 2007 Jun;81(11):5637-48. Epub 2007 Mar 7.

44.

Inhibition and escape of SARS-CoV treated with antisense morpholino oligomers.

Neuman BW, Stein DA, Kroeker AD, Moulton HM, Bestwick RK, Iversen PL, Buchmeier MJ.

Adv Exp Med Biol. 2006;581:567-71. Review. No abstract available.

PMID:
17037599
45.

Inhibition of coxsackievirus B3 in cell cultures and in mice by peptide-conjugated morpholino oligomers targeting the internal ribosome entry site.

Yuan J, Stein DA, Lim T, Qiu D, Coughlin S, Liu Z, Wang Y, Blouch R, Moulton HM, Iversen PL, Yang D.

J Virol. 2006 Dec;80(23):11510-9. Epub 2006 Sep 20.

46.

Inhibition of multiple subtypes of influenza A virus in cell cultures with morpholino oligomers.

Ge Q, Pastey M, Kobasa D, Puthavathana P, Lupfer C, Bestwick RK, Iversen PL, Chen J, Stein DA.

Antimicrob Agents Chemother. 2006 Nov;50(11):3724-33. Epub 2006 Sep 11.

47.

Patellofemoral arthritis.

Grelsamer RP, Stein DA.

J Bone Joint Surg Am. 2006 Aug;88(8):1849-60. Review. No abstract available.

PMID:
16882912
48.

Inhibition of replication and transcription activator and latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus by morpholino oligomers.

Zhang YJ, Wang KY, Stein DA, Patel D, Watkins R, Moulton HM, Iversen PL, Matson DO.

Antiviral Res. 2007 Jan;73(1):12-23. Epub 2006 Jun 14.

49.

Suppression of porcine reproductive and respiratory syndrome virus replication by morpholino antisense oligomers.

Zhang YJ, Stein DA, Fan SM, Wang KY, Kroeker AD, Meng XJ, Iversen PL, Matson DO.

Vet Microbiol. 2006 Oct 31;117(2-4):117-29. Epub 2006 Jul 12.

PMID:
16839712
50.

Age and ACL reconstruction revisited.

Stein DA, Brown H, Bartolozzi AR.

Orthopedics. 2006 Jun;29(6):533-6.

PMID:
16786946

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