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Items: 29

1.

Tobacco-Related Alterations in Airway Gene Expression are Rapidly Reversed Within Weeks Following Smoking-Cessation.

Hijazi K, Malyszko B, Steiling K, Xiao X, Liu G, Alekseyev YO, Dumas YM, Hertsgaard L, Jensen J, Hatsukami D, Brooks DR, O'Connor G, Beane J, Lenburg ME, Spira A.

Sci Rep. 2019 May 6;9(1):6978. doi: 10.1038/s41598-019-43295-3.

2.

Effect of long-term corticosteroid treatment on microRNA and gene-expression profiles in COPD.

Faiz A, Steiling K, Roffel MP, Postma DS, Spira A, Lenburg ME, Borggrewe M, Eijgenraam TR, Jonker MR, Koppelman GH, Pouwels SD, Liu G, Alekseyev YO, Lam S, Hiemstra PS, Sterk PJ, Timens W, Brandsma CA, Heijink IH, van den Berge M.

Eur Respir J. 2019 Apr 25;53(4). pii: 1801202. doi: 10.1183/13993003.01202-2018. Print 2019 Apr.

PMID:
30846474
3.

High-Throughput Sequencing in Respiratory, Critical Care, and Sleep Medicine Research. An Official American Thoracic Society Workshop Report.

Hersh CP, Adcock IM, Celedón JC, Cho MH, Christiani DC, Himes BE, Kaminski N, Mathias RA, Meyers DA, Quackenbush J, Redline S, Steiling KA, Tabor HK, Tobin MD, Wurfel MM, Yang IV, Koppelman GH.

Ann Am Thorac Soc. 2019 Jan;16(1):1-16. doi: 10.1513/AnnalsATS.201810-716WS.

4.

Lung Cancer Screening in a Safety-Net Hospital: Implications of Screening a Real-World Population versus the National Lung Screening Trial.

Iaccarino JM, Steiling KA, Wiener RS.

Ann Am Thorac Soc. 2018 Dec;15(12):1493-1495. doi: 10.1513/AnnalsATS.201806-389RL. No abstract available.

PMID:
30199643
5.

Breath of relief: apparent pulmonary nodule due to heterotopic ossification.

Abston E, Novaco R, Hon S, Scalera J, Steiling K.

Clin Case Rep. 2018 Apr 6;6(6):1174-1175. doi: 10.1002/ccr3.1378. eCollection 2018 Jun.

6.

Initial surgical experience following implementation of lung cancer screening at an urban safety net hospital.

Muñoz-Largacha JA, Steiling KA, Kathuria H, Charlot M, Fitzgerald C, Suzuki K, Litle VR.

J Thorac Cardiovasc Surg. 2018 Jun;155(6):2674-2681. doi: 10.1016/j.jtcvs.2017.12.135. Epub 2018 Feb 9.

PMID:
29534906
7.

Nasal gene expression differentiates COPD from controls and overlaps bronchial gene expression.

Boudewijn IM, Faiz A, Steiling K, van der Wiel E, Telenga ED, Hoonhorst SJM, Ten Hacken NHT, Brandsma CA, Kerstjens HAM, Timens W, Heijink IH, Jonker MR, de Bruin HG, Sebastiaan Vroegop J, Pasma HR, Boersma WG, Wielders P, van den Elshout F, Mansour K, Spira A, Lenburg ME, Guryev V, Postma DS, van den Berge M.

Respir Res. 2017 Dec 21;18(1):213. doi: 10.1186/s12931-017-0696-5.

8.

Shifting from Correlation to Causation: Challenges for the Future of Unbiased Molecular Studies in Inflammatory Lung Disease.

Christenson SA, Steiling K.

Am J Respir Crit Care Med. 2017 Jan 1;195(1):5-7. doi: 10.1164/rccm.201608-1751ED. No abstract available.

9.

Extranodal Marginal Zone Endobronchial Lymphoma Associated With Hepatitis C.

Bhatt N, Sloan JM, O'Hara CJ, Oommen R, Steiling K, Litle VR.

Ann Thorac Surg. 2016 Nov;102(5):e407-e408. doi: 10.1016/j.athoracsur.2016.04.060.

PMID:
27772593
10.

Gene-expression profiling of buccal epithelium among non-smoking women exposed to household air pollution from smoky coal.

Wang TW, Vermeulen RC, Hu W, Liu G, Xiao X, Alekseyev Y, Xu J, Reiss B, Steiling K, Downward GS, Silverman DT, Wei F, Wu G, Li J, Lenburg ME, Rothman N, Spira A, Lan Q.

Carcinogenesis. 2015 Dec;36(12):1494-501. doi: 10.1093/carcin/bgv150. Epub 2015 Oct 14.

11.

Targeting 'types: Precision Medicine in Pulmonary Disease.

Steiling K, Christenson SA.

Am J Respir Crit Care Med. 2015 May 15;191(10):1093-4. doi: 10.1164/rccm.201503-0613ED. No abstract available.

PMID:
25978565
12.

Defining the nasal transcriptome in granulomatosis with polyangiitis (Wegener's).

Grayson PC, Steiling K, Platt M, Berman JS, Zhang X, Xiao J, Alekseyev YO, Liu G, Monach PA, Kaplan MJ, Spira A, Merkel PA.

Arthritis Rheumatol. 2015 May;67(8):2233-9. doi: 10.1002/art.39185.

13.

Translating the transcriptome into tools for the early detection and prevention of lung cancer.

Gesthalter YB, Vick J, Steiling K, Spira A.

Thorax. 2015 May;70(5):476-81. doi: 10.1136/thoraxjnl-2014-206605. Epub 2015 Jan 27. Review.

PMID:
25628310
14.

Asthma-COPD overlap. Clinical relevance of genomic signatures of type 2 inflammation in chronic obstructive pulmonary disease.

Christenson SA, Steiling K, van den Berge M, Hijazi K, Hiemstra PS, Postma DS, Lenburg ME, Spira A, Woodruff PG.

Am J Respir Crit Care Med. 2015 Apr 1;191(7):758-66. doi: 10.1164/rccm.201408-1458OC.

15.

Catamenial hemothorax in a patient with multiple sclerosis.

Stevenson EK, Sloan KA, Narsule CK, Kretschman DM, Sarita-Reyes CD, Steiling K, Ebright MI.

Am J Respir Crit Care Med. 2014 Dec 15;190(12):e69-70. doi: 10.1164/rccm.201407-1283IM. No abstract available.

PMID:
25496111
16.

Genetic regulation of gene expression in the lung identifies CST3 and CD22 as potential causal genes for airflow obstruction.

Lamontagne M, Timens W, Hao K, Bossé Y, Laviolette M, Steiling K, Campbell JD, Couture C, Conti M, Sherwood K, Hogg JC, Brandsma CA, van den Berge M, Sandford A, Lam S, Lenburg ME, Spira A, Paré PD, Nickle D, Sin DD, Postma DS.

Thorax. 2014 Nov;69(11):997-1004. doi: 10.1136/thoraxjnl-2014-205630. Epub 2014 Sep 2.

PMID:
25182044
17.

Updates and controversies in the rapidly evolving field of lung cancer screening, early detection, and chemoprevention.

Kathuria H, Gesthalter Y, Spira A, Brody JS, Steiling K.

Cancers (Basel). 2014 May 16;6(2):1157-79. doi: 10.3390/cancers6021157.

18.

DNA methylation is globally disrupted and associated with expression changes in chronic obstructive pulmonary disease small airways.

Vucic EA, Chari R, Thu KL, Wilson IM, Cotton AM, Kennett JY, Zhang M, Lonergan KM, Steiling K, Brown CJ, McWilliams A, Ohtani K, Lenburg ME, Sin DD, Spira A, Macaulay CE, Lam S, Lam WL.

Am J Respir Cell Mol Biol. 2014 May;50(5):912-22. doi: 10.1165/rcmb.2013-0304OC.

19.

Personalized management of chronic obstructive pulmonary disease via transcriptomic profiling of the airway and lung.

Steiling K, Lenburg ME, Spira A.

Ann Am Thorac Soc. 2013 Dec;10 Suppl:S190-6. doi: 10.1513/AnnalsATS.201306-190AW. Review.

20.

Airway gene expression in COPD is dynamic with inhaled corticosteroid treatment and reflects biological pathways associated with disease activity.

van den Berge M, Steiling K, Timens W, Hiemstra PS, Sterk PJ, Heijink IH, Liu G, Alekseyev YO, Lenburg ME, Spira A, Postma DS.

Thorax. 2014 Jan;69(1):14-23. doi: 10.1136/thoraxjnl-2012-202878. Epub 2013 Aug 7.

21.

A dynamic bronchial airway gene expression signature of chronic obstructive pulmonary disease and lung function impairment.

Steiling K, van den Berge M, Hijazi K, Florido R, Campbell J, Liu G, Xiao J, Zhang X, Duclos G, Drizik E, Si H, Perdomo C, Dumont C, Coxson HO, Alekseyev YO, Sin D, Pare P, Hogg JC, McWilliams A, Hiemstra PS, Sterk PJ, Timens W, Chang JT, Sebastiani P, O'Connor GT, Bild AH, Postma DS, Lam S, Spira A, Lenburg ME.

Am J Respir Crit Care Med. 2013 May 1;187(9):933-42. doi: 10.1164/rccm.201208-1449OC.

22.

Transcriptomic studies of the airway field of injury associated with smoking-related lung disease.

Gower AC, Steiling K, Brothers JF 2nd, Lenburg ME, Spira A.

Proc Am Thorac Soc. 2011 May;8(2):173-9. doi: 10.1513/pats.201011-066MS.

23.

Interaction of cigarette exposure and airway epithelial cell gene expression.

Brody JS, Steiling K.

Annu Rev Physiol. 2011;73:437-56. doi: 10.1146/annurev-physiol-012110-142219. Review.

PMID:
21090967
24.

Airway gene expression in chronic obstructive pulmonary disease.

Steiling K, Lenburg ME, Spira A.

Proc Am Thorac Soc. 2009 Dec;6(8):697-700. doi: 10.1513/pats.200907-076DP. Review.

25.

Comparison of proteomic and transcriptomic profiles in the bronchial airway epithelium of current and never smokers.

Steiling K, Kadar AY, Bergerat A, Flanigon J, Sridhar S, Shah V, Ahmad QR, Brody JS, Lenburg ME, Steffen M, Spira A.

PLoS One. 2009;4(4):e5043. doi: 10.1371/journal.pone.0005043. Epub 2009 Apr 9.

26.

The field of tissue injury in the lung and airway.

Steiling K, Ryan J, Brody JS, Spira A.

Cancer Prev Res (Phila). 2008 Nov;1(6):396-403. doi: 10.1158/1940-6207.CAPR-08-0174. Review.

27.

A prediction model for lung cancer diagnosis that integrates genomic and clinical features.

Beane J, Sebastiani P, Whitfield TH, Steiling K, Dumas YM, Lenburg ME, Spira A.

Cancer Prev Res (Phila). 2008 Jun;1(1):56-64. doi: 10.1158/1940-6207.CAPR-08-0011. Epub 2008 Mar 31.

28.

Smoking-induced gene expression changes in the bronchial airway are reflected in nasal and buccal epithelium.

Sridhar S, Schembri F, Zeskind J, Shah V, Gustafson AM, Steiling K, Liu G, Dumas YM, Zhang X, Brody JS, Lenburg ME, Spira A.

BMC Genomics. 2008 May 30;9:259. doi: 10.1186/1471-2164-9-259.

29.

Airway epithelial gene expression in the diagnostic evaluation of smokers with suspect lung cancer.

Spira A, Beane JE, Shah V, Steiling K, Liu G, Schembri F, Gilman S, Dumas YM, Calner P, Sebastiani P, Sridhar S, Beamis J, Lamb C, Anderson T, Gerry N, Keane J, Lenburg ME, Brody JS.

Nat Med. 2007 Mar;13(3):361-6. Epub 2007 Mar 4.

PMID:
17334370

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