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Items: 12


Genome-wide Phenotypic Profiling Identifies and Categorizes Genes Required for Mycobacterial Low Iron Fitness.

Dragset MS, Ioerger TR, Zhang YJ, Mærk M, Ginbot Z, Sacchettini JC, Flo TH, Rubin EJ, Steigedal M.

Sci Rep. 2019 Aug 6;9(1):11394. doi: 10.1038/s41598-019-47905-y.


Genetic Variation/Evolution and Differential Host Responses Resulting from In-Patient Adaptation of Mycobacterium avium.

Kannan N, Lai YP, Haug M, Lilleness MK, Bakke SS, Marstad A, Hov H, Naustdal T, Afset JE, Ioerger TR, Flo TH, Steigedal M.

Infect Immun. 2019 Mar 25;87(4). pii: e00323-18. doi: 10.1128/IAI.00323-18. Print 2019 Apr.


Benzoic Acid-Inducible Gene Expression in Mycobacteria.

Dragset MS, Barczak AK, Kannan N, Mærk M, Flo TH, Valla S, Rubin EJ, Steigedal M.

PLoS One. 2015 Sep 8;10(9):e0134544. doi: 10.1371/journal.pone.0134544. eCollection 2015.


Keap1 regulates inflammatory signaling in Mycobacterium avium-infected human macrophages.

Awuh JA, Haug M, Mildenberger J, Marstad A, Do CP, Louet C, Stenvik J, Steigedal M, Damås JK, Halaas Ø, Flo TH.

Proc Natl Acad Sci U S A. 2015 Aug 4;112(31):E4272-80. doi: 10.1073/pnas.1423449112. Epub 2015 Jul 20.


A novel antimycobacterial compound acts as an intracellular iron chelator.

Dragset MS, Poce G, Alfonso S, Padilla-Benavides T, Ioerger TR, Kaneko T, Sacchettini JC, Biava M, Parish T, Argüello JM, Steigedal M, Rubin EJ.

Antimicrob Agents Chemother. 2015 Apr;59(4):2256-64. doi: 10.1128/AAC.05114-14. Epub 2015 Feb 2.


Lipocalin 2 imparts selective pressure on bacterial growth in the bladder and is elevated in women with urinary tract infection.

Steigedal M, Marstad A, Haug M, Damås JK, Strong RK, Roberts PL, Himpsl SD, Stapleton A, Hooton TM, Mobley HL, Hawn TR, Flo TH.

J Immunol. 2014 Dec 15;193(12):6081-9. doi: 10.4049/jimmunol.1401528. Epub 2014 Nov 14.


Mycobacterial Esx-3 requires multiple components for iron acquisition.

Siegrist MS, Steigedal M, Ahmad R, Mehra A, Dragset MS, Schuster BM, Philips JA, Carr SA, Rubin EJ.

MBio. 2014 May 6;5(3):e01073-14. doi: 10.1128/mBio.01073-14.


Dynamics of immune effector mechanisms during infection with Mycobacterium avium in C57BL/6 mice.

Haug M, Awuh JA, Steigedal M, Frengen Kojen J, Marstad A, Nordrum IS, Halaas Ø, Flo TH.

Immunology. 2013 Oct;140(2):232-43. doi: 10.1111/imm.12131.


Intracellular Mycobacterium avium intersect transferrin in the Rab11(+) recycling endocytic pathway and avoid lipocalin 2 trafficking to the lysosomal pathway.

Halaas O, Steigedal M, Haug M, Awuh JA, Ryan L, Brech A, Sato S, Husebye H, Cangelosi GA, Akira S, Strong RK, Espevik T, Flo TH.

J Infect Dis. 2010 Mar;201(5):783-92. doi: 10.1086/650493.


The Azotobacter vinelandii AlgE mannuronan C-5-epimerase family is essential for the in vivo control of alginate monomer composition and for functional cyst formation.

Steigedal M, Sletta H, Moreno S, Maerk M, Christensen BE, Bjerkan T, Ellingsen TE, Espìn G, Ertesvåg H, Valla S.

Environ Microbiol. 2008 Jul;10(7):1760-70. doi: 10.1111/j.1462-2920.2008.01597.x. Epub 2008 Mar 28.


Identification and characterization of an Azotobacter vinelandii type I secretion system responsible for export of the AlgE-type mannuronan C-5-epimerases.

Gimmestad M, Steigedal M, Ertesvåg H, Moreno S, Christensen BE, Espín G, Valla S.

J Bacteriol. 2006 Aug;188(15):5551-60.

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