Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 17

1.

A generalized HIV vaccine design strategy for priming of broadly neutralizing antibody responses.

Steichen JM, Lin YC, Havenar-Daughton C, Pecetta S, Ozorowski G, Willis JR, Toy L, Sok D, Liguori A, Kratochvil S, Torres JL, Kalyuzhniy O, Melzi E, Kulp DW, Raemisch S, Hu X, Bernard SM, Georgeson E, Phelps N, Adachi Y, Kubitz M, Landais E, Umotoy J, Robinson A, Briney B, Wilson IA, Burton DR, Ward AB, Crotty S, Batista FD, Schief WR.

Science. 2019 Dec 6;366(6470). pii: eaax4380. doi: 10.1126/science.aax4380. Epub 2019 Oct 31.

PMID:
31672916
2.

Innate immune recognition of glycans targets HIV nanoparticle immunogens to germinal centers.

Tokatlian T, Read BJ, Jones CA, Kulp DW, Menis S, Chang JYH, Steichen JM, Kumari S, Allen JD, Dane EL, Liguori A, Sangesland M, Lingwood D, Crispin M, Schief WR, Irvine DJ.

Science. 2019 Feb 8;363(6427):649-654. doi: 10.1126/science.aat9120. Epub 2018 Dec 20.

3.

One-step CRISPR/Cas9 method for the rapid generation of human antibody heavy chain knock-in mice.

Lin YC, Pecetta S, Steichen JM, Kratochvil S, Melzi E, Arnold J, Dougan SK, Wu L, Kirsch KH, Nair U, Schief WR, Batista FD.

EMBO J. 2018 Sep 14;37(18). pii: e99243. doi: 10.15252/embj.201899243. Epub 2018 Aug 7.

4.

Structure-based design of native-like HIV-1 envelope trimers to silence non-neutralizing epitopes and eliminate CD4 binding.

Kulp DW, Steichen JM, Pauthner M, Hu X, Schiffner T, Liguori A, Cottrell CA, Havenar-Daughton C, Ozorowski G, Georgeson E, Kalyuzhniy O, Willis JR, Kubitz M, Adachi Y, Reiss SM, Shin M, de Val N, Ward AB, Crotty S, Burton DR, Schief WR.

Nat Commun. 2017 Nov 21;8(1):1655. doi: 10.1038/s41467-017-01549-6.

5.

Elicitation of Robust Tier 2 Neutralizing Antibody Responses in Nonhuman Primates by HIV Envelope Trimer Immunization Using Optimized Approaches.

Pauthner M, Havenar-Daughton C, Sok D, Nkolola JP, Bastidas R, Boopathy AV, Carnathan DG, Chandrashekar A, Cirelli KM, Cottrell CA, Eroshkin AM, Guenaga J, Kaushik K, Kulp DW, Liu J, McCoy LE, Oom AL, Ozorowski G, Post KW, Sharma SK, Steichen JM, de Taeye SW, Tokatlian T, Torrents de la Peña A, Butera ST, LaBranche CC, Montefiori DC, Silvestri G, Wilson IA, Irvine DJ, Sanders RW, Schief WR, Ward AB, Wyatt RT, Barouch DH, Crotty S, Burton DR.

Immunity. 2017 Jun 20;46(6):1073-1088.e6. doi: 10.1016/j.immuni.2017.05.007.

6.

HIV Vaccine Design to Target Germline Precursors of Glycan-Dependent Broadly Neutralizing Antibodies.

Steichen JM, Kulp DW, Tokatlian T, Escolano A, Dosenovic P, Stanfield RL, McCoy LE, Ozorowski G, Hu X, Kalyuzhniy O, Briney B, Schiffner T, Garces F, Freund NT, Gitlin AD, Menis S, Georgeson E, Kubitz M, Adachi Y, Jones M, Mutafyan AA, Yun DS, Mayer CT, Ward AB, Burton DR, Wilson IA, Irvine DJ, Nussenzweig MC, Schief WR.

Immunity. 2016 Sep 20;45(3):483-496. doi: 10.1016/j.immuni.2016.08.016. Epub 2016 Sep 8.

7.

Sequential Immunization Elicits Broadly Neutralizing Anti-HIV-1 Antibodies in Ig Knockin Mice.

Escolano A, Steichen JM, Dosenovic P, Kulp DW, Golijanin J, Sok D, Freund NT, Gitlin AD, Oliveira T, Araki T, Lowe S, Chen ST, Heinemann J, Yao KH, Georgeson E, Saye-Francisco KL, Gazumyan A, Adachi Y, Kubitz M, Burton DR, Schief WR, Nussenzweig MC.

Cell. 2016 Sep 8;166(6):1445-1458.e12. doi: 10.1016/j.cell.2016.07.030.

8.

PKA: lessons learned after twenty years.

Taylor SS, Zhang P, Steichen JM, Keshwani MM, Kornev AP.

Biochim Biophys Acta. 2013 Jul;1834(7):1271-8. doi: 10.1016/j.bbapap.2013.03.007. Epub 2013 Mar 25. Review.

9.

Phosphoryl transfer by protein kinase A is captured in a crystal lattice.

Bastidas AC, Deal MS, Steichen JM, Guo Y, Wu J, Taylor SS.

J Am Chem Soc. 2013 Mar 27;135(12):4788-98. doi: 10.1021/ja312237q. Epub 2013 Mar 12.

10.

Evolution of the eukaryotic protein kinases as dynamic molecular switches.

Taylor SS, Keshwani MM, Steichen JM, Kornev AP.

Philos Trans R Soc Lond B Biol Sci. 2012 Sep 19;367(1602):2517-28. doi: 10.1098/rstb.2012.0054. Review.

11.

Role of N-terminal myristylation in the structure and regulation of cAMP-dependent protein kinase.

Bastidas AC, Deal MS, Steichen JM, Keshwani MM, Guo Y, Taylor SS.

J Mol Biol. 2012 Sep 14;422(2):215-29. doi: 10.1016/j.jmb.2012.05.021. Epub 2012 May 19.

12.

Structural basis for the regulation of protein kinase A by activation loop phosphorylation.

Steichen JM, Kuchinskas M, Keshwani MM, Yang J, Adams JA, Taylor SS.

J Biol Chem. 2012 Apr 27;287(18):14672-80. doi: 10.1074/jbc.M111.335091. Epub 2012 Feb 10.

13.

A conserved Glu-Arg salt bridge connects coevolved motifs that define the eukaryotic protein kinase fold.

Yang J, Wu J, Steichen JM, Kornev AP, Deal MS, Li S, Sankaran B, Woods VL Jr, Taylor SS.

J Mol Biol. 2012 Jan 27;415(4):666-79. doi: 10.1016/j.jmb.2011.11.035. Epub 2011 Nov 25.

14.

Global consequences of activation loop phosphorylation on protein kinase A.

Steichen JM, Iyer GH, Li S, Saldanha SA, Deal MS, Woods VL Jr, Taylor SS.

J Biol Chem. 2010 Feb 5;285(6):3825-32. doi: 10.1074/jbc.M109.061820. Epub 2009 Dec 4.

15.

Domain characterization of a 4-alpha-glucanotransferase essential for maltose metabolism in photosynthetic leaves.

Steichen JM, Petty RV, Sharkey TD.

J Biol Chem. 2008 Jul 25;283(30):20797-804. doi: 10.1074/jbc.M803051200. Epub 2008 May 22.

16.
17.

Cellular and organ level localization of maltose in maltose-excess Arabidopsis mutants.

Lu Y, Steichen JM, Weise SE, Sharkey TD.

Planta. 2006 Sep;224(4):935-43. Epub 2006 Apr 5.

PMID:
16596410

Supplemental Content

Loading ...
Support Center