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Items: 39

1.

Tumor Heterogeneity and Testing Discrepancy Confound ROS1 Detection in NSCLC.

Sun TY, Stehr H, Suarez CJ, Wakelee HA.

J Thorac Oncol. 2019 Jun;14(6):e111-e113. doi: 10.1016/j.jtho.2019.03.011. Epub 2019 Mar 23. No abstract available.

PMID:
30914313
2.

Reply to J. Wang et al.

Kurtz DM, Scherer F, Jin MC, Soo J, Craig AFM, Esfahani MS, Chabon JJ, Stehr H, Liu CL, Tibshirani R, Maeda LS, Gupta NK, Khodadoust MS, Advani RH, Newman AM, Dührsen U, Hüttmann A, Meignan M, Casasnovas O, Westin JR, Roschewski M, Wilson WH, Gaidano G, Rossi D, Diehn M, Alizadeh AA.

J Clin Oncol. 2019 Mar 20;37(9):755-757. doi: 10.1200/JCO.18.01907. Epub 2019 Feb 12. No abstract available.

PMID:
30753108
3.

Detection and Surveillance of Bladder Cancer Using Urine Tumor DNA.

Dudley JC, Schroers-Martin J, Lazzareschi DV, Shi WY, Chen SB, Esfahani MS, Trivedi D, Chabon JJ, Chaudhuri AA, Stehr H, Liu CL, Lim H, Costa HA, Nabet BY, Sin MLY, Liao JC, Alizadeh AA, Diehn M.

Cancer Discov. 2019 Apr;9(4):500-509. doi: 10.1158/2159-8290.CD-18-0825. Epub 2018 Dec 21.

PMID:
30578357
4.

Comparison of Genomic Driver Oncogenes in Vietnamese Patients With Non-Small-Cell Lung Cancer in the United States and Vietnam.

Nguyen KH, Stehr H, Zhou L, Nguyen AH, Hiep PN, Van Cau N, Duy PC, Thorp R, Wakelee HA, Diehn M, Neal JW.

J Glob Oncol. 2018 Nov;4:1-9. doi: 10.1200/JGO.18.00086.

PMID:
30422746
5.

Circulating Tumor DNA Measurements As Early Outcome Predictors in Diffuse Large B-Cell Lymphoma.

Kurtz DM, Scherer F, Jin MC, Soo J, Craig AFM, Esfahani MS, Chabon JJ, Stehr H, Liu CL, Tibshirani R, Maeda LS, Gupta NK, Khodadoust MS, Advani RH, Levy R, Newman AM, Dührsen U, Hüttmann A, Meignan M, Casasnovas RO, Westin JR, Roschewski M, Wilson WH, Gaidano G, Rossi D, Diehn M, Alizadeh AA.

J Clin Oncol. 2018 Oct 1;36(28):2845-2853. doi: 10.1200/JCO.2018.78.5246. Epub 2018 Aug 20.

PMID:
30125215
6.

Comprehensive Genomic Profiling of Malignant Effusions in Patients with Metastatic Lung Adenocarcinoma.

Yang SR, Lin CY, Stehr H, Long SR, Kong CS, Berry GJ, Zehnder JL, Kunder CA.

J Mol Diagn. 2018 Mar;20(2):184-194. doi: 10.1016/j.jmoldx.2017.10.007. Epub 2017 Dec 19.

PMID:
29269277
7.

Early Detection of Molecular Residual Disease in Localized Lung Cancer by Circulating Tumor DNA Profiling.

Chaudhuri AA, Chabon JJ, Lovejoy AF, Newman AM, Stehr H, Azad TD, Khodadoust MS, Esfahani MS, Liu CL, Zhou L, Scherer F, Kurtz DM, Say C, Carter JN, Merriott DJ, Dudley JC, Binkley MS, Modlin L, Padda SK, Gensheimer MF, West RB, Shrager JB, Neal JW, Wakelee HA, Loo BW Jr, Alizadeh AA, Diehn M.

Cancer Discov. 2017 Dec;7(12):1394-1403. doi: 10.1158/2159-8290.CD-17-0716. Epub 2017 Sep 24.

8.

Antigen presentation profiling reveals recognition of lymphoma immunoglobulin neoantigens.

Khodadoust MS, Olsson N, Wagar LE, Haabeth OA, Chen B, Swaminathan K, Rawson K, Liu CL, Steiner D, Lund P, Rao S, Zhang L, Marceau C, Stehr H, Newman AM, Czerwinski DK, Carlton VE, Moorhead M, Faham M, Kohrt HE, Carette J, Green MR, Davis MM, Levy R, Elias JE, Alizadeh AA.

Nature. 2017 Mar 30;543(7647):723-727. doi: 10.1038/nature21433. Epub 2017 Mar 22.

9.

Mutations of the aminoacyl-tRNA-synthetases SARS and WARS2 are implicated in the etiology of autosomal recessive intellectual disability.

Musante L, Püttmann L, Kahrizi K, Garshasbi M, Hu H, Stehr H, Lipkowitz B, Otto S, Jensen LR, Tzschach A, Jamali P, Wienker T, Najmabadi H, Ropers HH, Kuss AW.

Hum Mutat. 2017 Jun;38(6):621-636. doi: 10.1002/humu.23205. Epub 2017 Mar 23.

PMID:
28236339
10.

ERBB2-Mutated Metastatic Non-Small Cell Lung Cancer: Response and Resistance to Targeted Therapies.

Chuang JC, Stehr H, Liang Y, Das M, Huang J, Diehn M, Wakelee HA, Neal JW.

J Thorac Oncol. 2017 May;12(5):833-842. doi: 10.1016/j.jtho.2017.01.023. Epub 2017 Feb 4.

11.

Reprogramming the immunological microenvironment through radiation and targeting Axl.

Aguilera TA, Rafat M, Castellini L, Shehade H, Kariolis MS, Hui AB, Stehr H, von Eyben R, Jiang D, Ellies LG, Koong AC, Diehn M, Rankin EB, Graves EE, Giaccia AJ.

Nat Commun. 2016 Dec 23;7:13898. doi: 10.1038/ncomms13898.

12.

Corrigendum: Circulating tumour DNA profiling reveals heterogeneity of EGFR inhibitor resistance mechanisms in lung cancer patients.

Chabon JJ, Simmons AD, Lovejoy AF, Esfahani MS, Newman AM, Haringsma HJ, Kurtz DM, Stehr H, Scherer F, Karlovich CA, Harding TC, Durkin KA, Otterson GA, Thomas Purcell W, Ross Camidge D, Goldman JW, Sequist LV, Piotrowska Z, Wakelee HA, Neal JW, Alizadeh AA, Diehn M.

Nat Commun. 2016 Nov 14;7:13513. doi: 10.1038/ncomms13513. No abstract available.

13.

Distinct biological subtypes and patterns of genome evolution in lymphoma revealed by circulating tumor DNA.

Scherer F, Kurtz DM, Newman AM, Stehr H, Craig AF, Esfahani MS, Lovejoy AF, Chabon JJ, Klass DM, Liu CL, Zhou L, Glover C, Visser BC, Poultsides GA, Advani RH, Maeda LS, Gupta NK, Levy R, Ohgami RS, Kunder CA, Diehn M, Alizadeh AA.

Sci Transl Med. 2016 Nov 9;8(364):364ra155.

14.

Role of KEAP1/NRF2 and TP53 Mutations in Lung Squamous Cell Carcinoma Development and Radiation Resistance.

Jeong Y, Hoang NT, Lovejoy A, Stehr H, Newman AM, Gentles AJ, Kong W, Truong D, Martin S, Chaudhuri A, Heiser D, Zhou L, Say C, Carter JN, Hiniker SM, Loo BW Jr, West RB, Beachy P, Alizadeh AA, Diehn M.

Cancer Discov. 2017 Jan;7(1):86-101. doi: 10.1158/2159-8290.CD-16-0127. Epub 2016 Sep 23.

15.

Circulating tumour DNA profiling reveals heterogeneity of EGFR inhibitor resistance mechanisms in lung cancer patients.

Chabon JJ, Simmons AD, Lovejoy AF, Esfahani MS, Newman AM, Haringsma HJ, Kurtz DM, Stehr H, Scherer F, Karlovich CA, Harding TC, Durkin KA, Otterson GA, Purcell WT, Camidge DR, Goldman JW, Sequist LV, Piotrowska Z, Wakelee HA, Neal JW, Alizadeh AA, Diehn M.

Nat Commun. 2016 Jun 10;7:11815. doi: 10.1038/ncomms11815. Erratum in: Nat Commun. 2016 Nov 14;7:13513.

16.

Integrated digital error suppression for improved detection of circulating tumor DNA.

Newman AM, Lovejoy AF, Klass DM, Kurtz DM, Chabon JJ, Scherer F, Stehr H, Liu CL, Bratman SV, Say C, Zhou L, Carter JN, West RB, Sledge GW, Shrager JB, Loo BW Jr, Neal JW, Wakelee HA, Diehn M, Alizadeh AA.

Nat Biotechnol. 2016 May;34(5):547-555. doi: 10.1038/nbt.3520. Epub 2016 Mar 28.

17.

Long-Term Survival of a Patient With Non-Small-Cell Lung Cancer Harboring a V600E Mutation in the BRAF Oncogene.

Myall NJ, Neal JW, Cho-Phan CD, Zhou LY, Stehr H, Zhou L, Diehn M, Wakelee HA.

Clin Lung Cancer. 2016 Mar;17(2):e17-21. doi: 10.1016/j.cllc.2015.12.001. Epub 2015 Dec 18. No abstract available.

PMID:
26776917
18.

Mutations in the histamine N-methyltransferase gene, HNMT, are associated with nonsyndromic autosomal recessive intellectual disability.

Heidari A, Tongsook C, Najafipour R, Musante L, Vasli N, Garshasbi M, Hu H, Mittal K, McNaughton AJ, Sritharan K, Hudson M, Stehr H, Talebi S, Moradi M, Darvish H, Arshad Rafiq M, Mozhdehipanah H, Rashidinejad A, Samiei S, Ghadami M, Windpassinger C, Gillessen-Kaesbach G, Tzschach A, Ahmed I, Mikhailov A, Stavropoulos DJ, Carter MT, Keshavarz S, Ayub M, Najmabadi H, Liu X, Ropers HH, Macheroux P, Vincent JB.

Hum Mol Genet. 2015 Oct 15;24(20):5697-710. doi: 10.1093/hmg/ddv286. Epub 2015 Jul 23.

19.

The Art of Service Learning.

Condon BB, Grimsley C, Knaack L, Pitz J, Stehr HJ.

Nurs Sci Q. 2015 Jul;28(3):195-200. doi: 10.1177/0894318415585624.

PMID:
26109693
20.

Mutations in early follicular lymphoma progenitors are associated with suppressed antigen presentation.

Green MR, Kihira S, Liu CL, Nair RV, Salari R, Gentles AJ, Irish J, Stehr H, Vicente-Dueñas C, Romero-Camarero I, Sanchez-Garcia I, Plevritis SK, Arber DA, Batzoglou S, Levy R, Alizadeh AA.

Proc Natl Acad Sci U S A. 2015 Mar 10;112(10):E1116-25. doi: 10.1073/pnas.1501199112. Epub 2015 Feb 23.

21.

FACTERA: a practical method for the discovery of genomic rearrangements at breakpoint resolution.

Newman AM, Bratman SV, Stehr H, Lee LJ, Liu CL, Diehn M, Alizadeh AA.

Bioinformatics. 2014 Dec 1;30(23):3390-3. doi: 10.1093/bioinformatics/btu549. Epub 2014 Aug 20.

22.

A novel ALDH5A1 mutation is associated with succinic semialdehyde dehydrogenase deficiency and severe intellectual disability in an Iranian family.

Püttmann L, Stehr H, Garshasbi M, Hu H, Kahrizi K, Lipkowitz B, Jamali P, Tzschach A, Najmabadi H, Ropers HH, Musante L, Kuss AW.

Am J Med Genet A. 2013 Aug;161A(8):1915-22. doi: 10.1002/ajmg.a.36030. Epub 2013 Jul 4.

PMID:
23825041
23.

Integrative genomic analyses reveal an androgen-driven somatic alteration landscape in early-onset prostate cancer.

Weischenfeldt J, Simon R, Feuerbach L, Schlangen K, Weichenhan D, Minner S, Wuttig D, Warnatz HJ, Stehr H, Rausch T, Jäger N, Gu L, Bogatyrova O, Stütz AM, Claus R, Eils J, Eils R, Gerhäuser C, Huang PH, Hutter B, Kabbe R, Lawerenz C, Radomski S, Bartholomae CC, Fälth M, Gade S, Schmidt M, Amschler N, Haß T, Galal R, Gjoni J, Kuner R, Baer C, Masser S, von Kalle C, Zichner T, Benes V, Raeder B, Mader M, Amstislavskiy V, Avci M, Lehrach H, Parkhomchuk D, Sultan M, Burkhardt L, Graefen M, Huland H, Kluth M, Krohn A, Sirma H, Stumm L, Steurer S, Grupp K, Sültmann H, Sauter G, Plass C, Brors B, Yaspo ML, Korbel JO, Schlomm T.

Cancer Cell. 2013 Feb 11;23(2):159-70. doi: 10.1016/j.ccr.2013.01.002.

24.

Hsp90 inhibition differentially destabilises MAP kinase and TGF-beta signalling components in cancer cells revealed by kinase-targeted chemoproteomics.

Haupt A, Joberty G, Bantscheff M, Fröhlich H, Stehr H, Schweiger MR, Fischer A, Kerick M, Boerno ST, Dahl A, Lappe M, Lehrach H, Gonzalez C, Drewes G, Lange BM.

BMC Cancer. 2012 Jan 25;12:38. doi: 10.1186/1471-2407-12-38.

25.

The structural impact of cancer-associated missense mutations in oncogenes and tumor suppressors.

Stehr H, Jang SH, Duarte JM, Wierling C, Lehrach H, Lappe M, Lange BM.

Mol Cancer. 2011 May 16;10:54. doi: 10.1186/1476-4598-10-54.

26.

CMView: interactive contact map visualization and analysis.

Vehlow C, Stehr H, Winkelmann M, Duarte JM, Petzold L, Dinse J, Lappe M.

Bioinformatics. 2011 Jun 1;27(11):1573-4. doi: 10.1093/bioinformatics/btr163. Epub 2011 Apr 5.

PMID:
21471016
27.

PDBWiki: added value through community annotation of the Protein Data Bank.

Stehr H, Duarte JM, Lappe M, Bhak J, Bolser DM.

Database (Oxford). 2010 Jul 6;2010:baq009. doi: 10.1093/database/baq009.

28.

Optimal contact definition for reconstruction of contact maps.

Duarte JM, Sathyapriya R, Stehr H, Filippis I, Lappe M.

BMC Bioinformatics. 2010 May 27;11:283. doi: 10.1186/1471-2105-11-283.

29.

Defining an essence of structure determining residue contacts in proteins.

Sathyapriya R, Duarte JM, Stehr H, Filippis I, Lappe M.

PLoS Comput Biol. 2009 Dec;5(12):e1000584. doi: 10.1371/journal.pcbi.1000584. Epub 2009 Dec 4.

30.

Designing evolvable libraries using multi-body potentials.

Lappe M, Bagler G, Filippis I, Stehr H, Duarte JM, Sathyapriya R.

Curr Opin Biotechnol. 2009 Aug;20(4):437-46. doi: 10.1016/j.copbio.2009.07.008. Epub 2009 Aug 26. Review.

PMID:
19713097
31.

Residue contact-count potentials are as effective as residue-residue contact-type potentials for ranking protein decoys.

Bolser DM, Filippis I, Stehr H, Duarte J, Lappe M.

BMC Struct Biol. 2008 Dec 8;8:53. doi: 10.1186/1472-6807-8-53.

32.
33.

[Research and development in medical technology industry--status in Germany].

Stehr H.

Langenbecks Arch Chir Suppl Kongressbd. 1996;113:651-3. German.

PMID:
9101961
34.
35.

[Economic and structural aspects of modern medical technology].

Stehr H.

Aktuelle Radiol. 1993 Sep;3(5):323-9. Review. German.

PMID:
8399425
36.

[Global cost analysis of radiological procedures].

Stehr H.

Aktuelle Radiol. 1991 Sep;1(5):271-6. German.

PMID:
1751567
37.

[Long-term results after local thrombolysis in acute massive pulmonary embolism].

Schwarz F, Stehr H, Zimmermann R, Manthey J, Harenberg J, Kübler W.

Dtsch Med Wochenschr. 1985 Feb 22;110(8):293-7. German.

PMID:
3971880
38.
39.

[Local thrombolysis with urokinase in acute massive pulmonary embolism].

Schwarz F, Zimmermann R, Stehr H, Harenberg J, Kübler W.

Dtsch Med Wochenschr. 1984 Jan 13;109(2):55-8. German.

PMID:
6692763

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