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Items: 30


AMPK activation caused by reduced liver lactate metabolism protects against hepatic steatosis in MCT1 haploinsufficient mice.

Carneiro L, Asrih M, Repond C, Sempoux C, Stehle JC, Leloup C, Jornayvaz FR, Pellerin L.

Mol Metab. 2017 Dec;6(12):1625-1633. doi: 10.1016/j.molmet.2017.10.005. Epub 2017 Oct 20.


Acidic tumor microenvironment abrogates the efficacy of mTORC1 inhibitors.

Faes S, Duval AP, Planche A, Uldry E, Santoro T, Pythoud C, Stehle JC, Horlbeck J, Letovanec I, Riggi N, Demartines N, Dormond O.

Mol Cancer. 2016 Dec 5;15(1):78.


Targeting carbonic anhydrase IX improves the anti-cancer efficacy of mTOR inhibitors.

Faes S, Planche A, Uldry E, Santoro T, Pythoud C, Stehle JC, Horlbeck J, Letovanec I, Riggi N, Datta D, Demartines N, Dormond O.

Oncotarget. 2016 Jun 14;7(24):36666-36680. doi: 10.18632/oncotarget.9134.


Severe pneumonia due to Parachlamydia acanthamoebae following intranasal inoculation: a mice model.

Pilloux L, Casson N, Sommer K, Klos A, Stehle JC, Pusztaszeri M, Greub G.

Microbes Infect. 2015 Nov-Dec;17(11-12):755-60. doi: 10.1016/j.micinf.2015.08.007. Epub 2015 Sep 1.


Effects of Sucroferric Oxyhydroxide Compared to Lanthanum Carbonate and Sevelamer Carbonate on Phosphate Homeostasis and Vascular Calcifications in a Rat Model of Chronic Kidney Failure.

Phan O, Maillard M, Malluche HH, Stehle JC, Funk F, Burnier M.

Biomed Res Int. 2015;2015:515606. doi: 10.1155/2015/515606. Epub 2015 Jun 29.


Resistance to diet-induced obesity and associated metabolic perturbations in haploinsufficient monocarboxylate transporter 1 mice.

Lengacher S, Nehiri-Sitayeb T, Steiner N, Carneiro L, Favrod C, Preitner F, Thorens B, Stehle JC, Dix L, Pralong F, Magistretti PJ, Pellerin L.

PLoS One. 2013 Dec 18;8(12):e82505. doi: 10.1371/journal.pone.0082505. eCollection 2013.


PA21, a new iron-based noncalcium phosphate binder, prevents vascular calcification in chronic renal failure rats.

Phan O, Maillard M, Peregaux C, Mordasini D, Stehle JC, Funk F, Burnier M.

J Pharmacol Exp Ther. 2013 Aug;346(2):281-9. doi: 10.1124/jpet.113.204792. Epub 2013 May 22.


The channel-activating protease CAP1/Prss8 is required for placental labyrinth maturation.

Hummler E, Dousse A, Rieder A, Stehle JC, Rubera I, Osterheld MC, Beermann F, Frateschi S, Charles RP.

PLoS One. 2013;8(2):e55796. doi: 10.1371/journal.pone.0055796. Epub 2013 Feb 6.


Inhibition of the Kit ligand/c-Kit axis attenuates metastasis in a mouse model mimicking local breast cancer relapse after radiotherapy.

Kuonen F, Laurent J, Secondini C, Lorusso G, Stehle JC, Rausch T, Faes-Van't Hull E, Bieler G, Alghisi GC, Schwendener R, Andrejevic-Blant S, Mirimanoff RO, Rüegg C.

Clin Cancer Res. 2012 Aug 15;18(16):4365-74. Epub 2012 Jun 18.


The glucocorticoid-induced leucine zipper (gilz/Tsc22d3-2) gene locus plays a crucial role in male fertility.

Suarez PE, Rodriguez EG, Soundararajan R, Mérillat AM, Stehle JC, Rotman S, Roger T, Voirol MJ, Wang J, Gross O, Pétrilli V, Nadra K, Wilson A, Beermann F, Pralong FP, Maillard M, Pearce D, Chrast R, Rossier BC, Hummler E.

Mol Endocrinol. 2012 Jun;26(6):1000-13. doi: 10.1210/me.2011-1249. Epub 2012 May 3.


Myeloid-derived suppressor cells are implicated in regulating permissiveness for tumor metastasis during mouse gestation.

Mauti LA, Le Bitoux MA, Baumer K, Stehle JC, Golshayan D, Provero P, Stamenkovic I.

J Clin Invest. 2011 Jul;121(7):2794-807. doi: 10.1172/JCI41936. Epub 2011 Jun 6.


Identification of prognostic molecular features in the reactive stroma of human breast and prostate cancer.

Planche A, Bacac M, Provero P, Fusco C, Delorenzi M, Stehle JC, Stamenkovic I.

PLoS One. 2011;6(5):e18640. doi: 10.1371/journal.pone.0018640. Epub 2011 May 18.


PAR2 absence completely rescues inflammation and ichthyosis caused by altered CAP1/Prss8 expression in mouse skin.

Frateschi S, Camerer E, Crisante G, Rieser S, Membrez M, Charles RP, Beermann F, Stehle JC, Breiden B, Sandhoff K, Rotman S, Haftek M, Wilson A, Ryser S, Steinhoff M, Coughlin SR, Hummler E.

Nat Commun. 2011 Jan 18;2:161.


alphaENaC-mediated lithium absorption promotes nephrogenic diabetes insipidus.

Christensen BM, Zuber AM, Loffing J, Stehle JC, Deen PM, Rossier BC, Hummler E.

J Am Soc Nephrol. 2011 Feb;22(2):253-61. doi: 10.1681/ASN.2010070734. Epub 2010 Nov 4.


Sodium and potassium balance depends on αENaC expression in connecting tubule.

Christensen BM, Perrier R, Wang Q, Zuber AM, Maillard M, Mordasini D, Malsure S, Ronzaud C, Stehle JC, Rossier BC, Hummler E.

J Am Soc Nephrol. 2010 Nov;21(11):1942-51. doi: 10.1681/ASN.2009101077. Epub 2010 Oct 14.


Bcl9/Bcl9l are critical for Wnt-mediated regulation of stem cell traits in colon epithelium and adenocarcinomas.

Deka J, Wiedemann N, Anderle P, Murphy-Seiler F, Bultinck J, Eyckerman S, Stehle JC, André S, Vilain N, Zilian O, Robine S, Delorenzi M, Basler K, Aguet M.

Cancer Res. 2010 Aug 15;70(16):6619-28. doi: 10.1158/0008-5472.CAN-10-0148. Epub 2010 Aug 3.


A novel mucosal orthotopic murine model of human papillomavirus-associated genital cancers.

Decrausaz L, Gonçalves AR, Domingos-Pereira S, Pythoud C, Stehle JC, Schiller J, Jichlinski P, Nardelli-Haefliger D.

Int J Cancer. 2011 May 1;128(9):2105-13. doi: 10.1002/ijc.25561.


EWS-FLI-1 modulates miRNA145 and SOX2 expression to initiate mesenchymal stem cell reprogramming toward Ewing sarcoma cancer stem cells.

Riggi N, Suvà ML, De Vito C, Provero P, Stehle JC, Baumer K, Cironi L, Janiszewska M, Petricevic T, Suvà D, Tercier S, Joseph JM, Guillou L, Stamenkovic I.

Genes Dev. 2010 May;24(9):916-32. doi: 10.1101/gad.1899710. Epub 2010 Apr 9.


EZH2 is essential for glioblastoma cancer stem cell maintenance.

Suvà ML, Riggi N, Janiszewska M, Radovanovic I, Provero P, Stehle JC, Baumer K, Le Bitoux MA, Marino D, Cironi L, Marquez VE, Clément V, Stamenkovic I.

Cancer Res. 2009 Dec 15;69(24):9211-8. doi: 10.1158/0008-5472.CAN-09-1622.


Malarial hemozoin is a Nalp3 inflammasome activating danger signal.

Dostert C, Guarda G, Romero JF, Menu P, Gross O, Tardivel A, Suva ML, Stehle JC, Kopf M, Stamenkovic I, Corradin G, Tschopp J.

PLoS One. 2009 Aug 4;4(8):e6510. doi: 10.1371/journal.pone.0006510.


Identification of cancer stem cells in Ewing's sarcoma.

Suvà ML, Riggi N, Stehle JC, Baumer K, Tercier S, Joseph JM, Suvà D, Clément V, Provero P, Cironi L, Osterheld MC, Guillou L, Stamenkovic I.

Cancer Res. 2009 Mar 1;69(5):1776-81. doi: 10.1158/0008-5472.CAN-08-2242. Epub 2009 Feb 10.


CYR61 and alphaVbeta5 integrin cooperate to promote invasion and metastasis of tumors growing in preirradiated stroma.

Monnier Y, Farmer P, Bieler G, Imaizumi N, Sengstag T, Alghisi GC, Stehle JC, Ciarloni L, Andrejevic-Blant S, Moeckli R, Mirimanoff RO, Goodman SL, Delorenzi M, Rüegg C.

Cancer Res. 2008 Sep 15;68(18):7323-31. doi: 10.1158/0008-5472.CAN-08-0841.


EWS-FLI-1 expression triggers a Ewing's sarcoma initiation program in primary human mesenchymal stem cells.

Riggi N, Suvà ML, Suvà D, Cironi L, Provero P, Tercier S, Joseph JM, Stehle JC, Baumer K, Kindler V, Stamenkovic I.

Cancer Res. 2008 Apr 1;68(7):2176-85. doi: 10.1158/0008-5472.CAN-07-1761.


Intravaginal immunization of mice with recombinant Salmonella enterica serovar Typhimurium expressing human papillomavirus type 16 antigens as a potential route of vaccination against cervical cancer.

Echchannaoui H, Bianchi M, Baud D, Bobst M, Stehle JC, Nardelli-Haefliger D.

Infect Immun. 2008 May;76(5):1940-51. doi: 10.1128/IAI.01484-07. Epub 2008 Mar 10.


Postnatal requirement of the epithelial sodium channel for maintenance of epidermal barrier function.

Charles RP, Guitard M, Leyvraz C, Breiden B, Haftek M, Haftek-Terreau Z, Stehle JC, Sandhoff K, Hummler E.

J Biol Chem. 2008 Feb 1;283(5):2622-30. Epub 2007 Nov 26.


A mouse stromal response to tumor invasion predicts prostate and breast cancer patient survival.

Bacac M, Provero P, Mayran N, Stehle JC, Fusco C, Stamenkovic I.

PLoS One. 2006 Dec 20;1:e32.


Expression of the FUS-CHOP fusion protein in primary mesenchymal progenitor cells gives rise to a model of myxoid liposarcoma.

Riggi N, Cironi L, Provero P, Suvà ML, Stehle JC, Baumer K, Guillou L, Stamenkovic I.

Cancer Res. 2006 Jul 15;66(14):7016-23.


A gene expression signature that distinguishes desmoid tumours from nodular fasciitis.

Bacac M, Migliavacca E, Stehle JC, McKee T, Delorenzi M, Coindre JM, Guillou L, Stamenkovic I.

J Pathol. 2006 Mar;208(4):543-53.


Immunohistochemical localization of hTERT protein in human tissues.

Yan P, Benhattar J, Seelentag W, Stehle JC, Bosman FT.

Histochem Cell Biol. 2004 May;121(5):391-7. Epub 2004 May 7.


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