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Items: 1 to 50 of 77

1.

High Frequency Spectral Ultrasound Imaging to Detect Metastasis in Implanted Biomaterial Scaffolds.

Bushnell GG, Hong X, Hartfield RM, Zhang Y, Oakes RS, Rao SS, Jeruss JS, Stegemann JP, Deng CX, Shea LD.

Ann Biomed Eng. 2019 Sep 23. doi: 10.1007/s10439-019-02366-2. [Epub ahead of print]

PMID:
31549327
2.

Injectable osteogenic microtissues containing mesenchymal stromal cells conformally fill and repair critical-size defects.

Annamalai RT, Hong X, Schott NG, Tiruchinapally G, Levi B, Stegemann JP.

Biomaterials. 2019 Jul;208:32-44. doi: 10.1016/j.biomaterials.2019.04.001. Epub 2019 Apr 4.

PMID:
30991216
3.

Development of Modular, Dual-Perfused Osteochondral Constructs for Cartilage Repair.

Daley ELH, Kuttig J, Stegemann JP.

Tissue Eng Part C Methods. 2019 Mar;25(3):127-136. doi: 10.1089/ten.TEC.2018.0356.

PMID:
30724134
4.

Spatiotemporally-controlled transgene expression in hydroxyapatite-fibrin composite scaffolds using high intensity focused ultrasound.

Moncion A, Harmon JS, Li Y, Natla S, Farrell EC, Kripfgans OD, Stegemann JP, Martín-Saavedra FM, Vilaboa N, Franceschi RT, Fabiilli ML.

Biomaterials. 2019 Feb;194:14-24. doi: 10.1016/j.biomaterials.2018.12.011. Epub 2018 Dec 13.

PMID:
30572283
5.

Multimode ultrasound viscoelastography for three-dimensional interrogation of microscale mechanical properties in heterogeneous biomaterials.

Hong X, Annamalai RT, Kemerer TS, Deng CX, Stegemann JP.

Biomaterials. 2018 Sep;178:11-22. doi: 10.1016/j.biomaterials.2018.05.057. Epub 2018 Jun 2.

PMID:
29902533
6.

Biofabrication of injectable fibrin microtissues for minimally-invasive therapies: application of surfactants.

Annamalai RT, Naik TN, Prout HP, Putnam AJ, Stegemann JP.

Biomed Mater. 2018 Apr 16;13(4):045005. doi: 10.1088/1748-605X/aab66f.

7.

Harnessing macrophage-mediated degradation of gelatin microspheres for spatiotemporal control of BMP2 release.

Annamalai RT, Turner PA, Carson WF 4th, Levi B, Kunkel S, Stegemann JP.

Biomaterials. 2018 Apr;161:216-227. doi: 10.1016/j.biomaterials.2018.01.040. Epub 2018 Feb 3.

8.

High-frequency spectral ultrasound imaging (SUSI) visualizes early post-traumatic heterotopic ossification (HO) in a mouse model.

Ranganathan K, Hong X, Cholok D, Habbouche J, Priest C, Breuler C, Chung M, Li J, Kaura A, Hsieh HHS, Butts J, Ucer S, Schwartz E, Buchman SR, Stegemann JP, Deng CX, Levi B.

Bone. 2018 Apr;109:49-55. doi: 10.1016/j.bone.2018.01.034. Epub 2018 Feb 14.

9.

Engineering the geometrical shape of mesenchymal stromal cells through defined cyclic stretch regimens.

Walters B, Uynuk-Ool T, Rothdiener M, Palm J, Hart ML, Stegemann JP, Rolauffs B.

Sci Rep. 2017 Jul 26;7(1):6640. doi: 10.1038/s41598-017-06794-9.

10.

Growth factor sequestration and enzyme-mediated release from genipin-crosslinked gelatin microspheres.

Turner PA, Thiele JS, Stegemann JP.

J Biomater Sci Polym Ed. 2017 Nov;28(16):1826-1846. doi: 10.1080/09205063.2017.1354672. Epub 2017 Jul 20.

11.

The geometrical shape of mesenchymal stromal cells measured by quantitative shape descriptors is determined by the stiffness of the biomaterial and by cyclic tensile forces.

Uynuk-Ool T, Rothdiener M, Walters B, Hegemann M, Palm J, Nguyen P, Seeger T, Stöckle U, Stegemann JP, Aicher WK, Kurz B, Hart ML, Klein G, Rolauffs B.

J Tissue Eng Regen Med. 2017 Dec;11(12):3508-3522. doi: 10.1002/term.2263. Epub 2017 Mar 29.

12.

Distributed vasculogenesis from modular agarose-hydroxyapatite-fibrinogen microbeads.

Rioja AY, Daley ELH, Habif JC, Putnam AJ, Stegemann JP.

Acta Biomater. 2017 Jun;55:144-152. doi: 10.1016/j.actbio.2017.03.050. Epub 2017 Mar 29.

13.

Vascular Network Formation by Human Microvascular Endothelial Cells in Modular Fibrin Microtissues.

Tiruvannamalai Annamalai R, Rioja AY, Putnam AJ, Stegemann JP.

ACS Biomater Sci Eng. 2016 Nov 14;2(11):1914-1925. doi: 10.1021/acsbiomaterials.6b00274. Epub 2016 Sep 27.

14.
15.

Stretching human mesenchymal stromal cells on stiffness-customized collagen type I generates a smooth muscle marker profile without growth factor addition.

Rothdiener M, Hegemann M, Uynuk-Ool T, Walters B, Papugy P, Nguyen P, Claus V, Seeger T, Stoeckle U, Boehme KA, Aicher WK, Stegemann JP, Hart ML, Kurz B, Klein G, Rolauffs B.

Sci Rep. 2016 Oct 24;6:35840. doi: 10.1038/srep35840.

16.

Tissue engineering and regenerative approaches to improving the healing of large bone defects.

Verrier S, Alini M, Alsberg E, Buchman SR, Kelly D, Laschke MW, Menger MD, Murphy WL, Stegemann JP, Schütz M, Miclau T, Stoddart MJ, Evans C.

Eur Cell Mater. 2016 Jul 19;32:87-110. Review.

17.

Microscale characterization of the viscoelastic properties of hydrogel biomaterials using dual-mode ultrasound elastography.

Hong X, Stegemann JP, Deng CX.

Biomaterials. 2016 May;88:12-24. doi: 10.1016/j.biomaterials.2016.02.019. Epub 2016 Feb 18.

18.

Collagen Type II enhances chondrogenic differentiation in agarose-based modular microtissues.

Tiruvannamalai Annamalai R, Mertz DR, Daley EL, Stegemann JP.

Cytotherapy. 2016 Feb;18(2):263-77. doi: 10.1016/j.jcyt.2015.10.015.

19.

Ultrasound Imaging Techniques for Spatiotemporal Characterization of Composition, Microstructure, and Mechanical Properties in Tissue Engineering.

Deng CX, Hong X, Stegemann JP.

Tissue Eng Part B Rev. 2016 Aug;22(4):311-21. doi: 10.1089/ten.TEB.2015.0453. Epub 2016 Mar 14. Review.

20.

Biomimetic microbeads containing a chondroitin sulfate/chitosan polyelectrolyte complex for cell-based cartilage therapy.

Daley EL, Coleman RM, Stegemann JP.

J Mater Chem B. 2015 Oct 28;3(40):7920-7929. Epub 2015 Jul 24.

21.

Endothelial sprouting and network formation in collagen- and fibrin-based modular microbeads.

Rioja AY, Tiruvannamalai Annamalai R, Paris S, Putnam AJ, Stegemann JP.

Acta Biomater. 2016 Jan;29:33-41. doi: 10.1016/j.actbio.2015.10.022. Epub 2015 Oct 23.

22.

Using a 3D Culture System to Differentiate Visceral Adipocytes In Vitro.

Emont MP, Yu H, Jun H, Hong X, Maganti N, Stegemann JP, Wu J.

Endocrinology. 2015 Dec;156(12):4761-8. doi: 10.1210/en.2015-1567. Epub 2015 Oct 1.

23.

Dual-phase osteogenic and vasculogenic engineered tissue for bone formation.

Rao RR, Vigen ML, Peterson AW, Caldwell DJ, Putnam AJ, Stegemann JP.

Tissue Eng Part A. 2015 Feb;21(3-4):530-40. doi: 10.1089/ten.TEA.2013.0740. Epub 2014 Oct 17.

24.

Vasculogenesis and Angiogenesis in Modular Collagen-Fibrin Microtissues.

Peterson AW, Caldwell DJ, Rioja AY, Rao RR, Putnam AJ, Stegemann JP.

Biomater Sci. 2014 Oct 1;2(10):1497-1508.

25.

Cell therapy for bone repair: narrowing the gap between vision and practice.

Stegemann JP, Verrier S, Gebhard F, Laschke MW, Martin I, Simpson H, Miclau T.

Eur Cell Mater. 2014 May 6;27:1-4.

26.

Injection of mesenchymal stromal cells into a mechanically stimulated in vitro model of cardiac fibrosis has paracrine effects on resident fibroblasts.

Galie PA, Stegemann JP.

Cytotherapy. 2014 Jul;16(7):906-14. doi: 10.1016/j.jcyt.2014.01.416. Epub 2014 Apr 6.

27.

Effects of hydroxyapatite on endothelial network formation in collagen/fibrin composite hydrogels in vitro and in vivo.

Rao RR, Ceccarelli J, Vigen ML, Gudur M, Singh R, Deng CX, Putnam AJ, Stegemann JP.

Acta Biomater. 2014 Jul;10(7):3091-7. doi: 10.1016/j.actbio.2014.03.010. Epub 2014 Mar 18.

28.

Noninvasive quantification of in vitro osteoblastic differentiation in 3D engineered tissue constructs using spectral ultrasound imaging.

Gudur MS, Rao RR, Peterson AW, Caldwell DJ, Stegemann JP, Deng CX.

PLoS One. 2014 Jan 22;9(1):e85749. doi: 10.1371/journal.pone.0085749. eCollection 2014.

29.

A poroelastic model describing nutrient transport and cell stresses within a cyclically strained collagen hydrogel.

Vaughan BL Jr, Galie PA, Stegemann JP, Grotberg JB.

Biophys J. 2013 Nov 5;105(9):2188-98. doi: 10.1016/j.bpj.2013.08.048.

30.

Strategies for directing the structure and function of three-dimensional collagen biomaterials across length scales.

Walters BD, Stegemann JP.

Acta Biomater. 2014 Apr;10(4):1488-501. doi: 10.1016/j.actbio.2013.08.038. Epub 2013 Sep 6. Review.

31.

Cell-based approaches to the engineering of vascularized bone tissue.

Rao RR, Stegemann JP.

Cytotherapy. 2013 Nov;15(11):1309-22. doi: 10.1016/j.jcyt.2013.06.005. Epub 2013 Aug 31. Review.

32.

Comparison of uncultured marrow mononuclear cells and culture-expanded mesenchymal stem cells in 3D collagen-chitosan microbeads for orthopedic tissue engineering.

Wise JK, Alford AI, Goldstein SA, Stegemann JP.

Tissue Eng Part A. 2014 Jan;20(1-2):210-24. doi: 10.1089/ten.TEA.2013.0151. Epub 2013 Sep 26.

33.

Delivery of mesenchymal stem cells in chitosan/collagen microbeads for orthopedic tissue repair.

Wang L, Rao RR, Stegemann JP.

Cells Tissues Organs. 2013;197(5):333-43. doi: 10.1159/000348359. Epub 2013 Apr 3.

35.

Substrate stiffness affects sarcomere and costamere structure and electrophysiological function of isolated adult cardiomyocytes.

Galie PA, Khalid N, Carnahan KE, Westfall MV, Stegemann JP.

Cardiovasc Pathol. 2013 May-Jun;22(3):219-27. doi: 10.1016/j.carpath.2012.10.003. Epub 2012 Dec 21.

36.

Assembly of discrete collagen-chitosan microenvironments into multiphase tissue constructs.

Caldwell DJ, Rao RR, Stegemann JP.

Adv Healthc Mater. 2013 May;2(5):673-7. doi: 10.1002/adhm.201200346. Epub 2012 Nov 26.

37.

Use of micro-computed tomography to nondestructively characterize biomineral coatings on solid freeform fabricated poly (L-lactic acid) and poly ((ε-caprolactone) scaffolds in vitro and in vivo.

Saito E, Suarez-Gonzalez D, Rao RR, Stegemann JP, Murphy WL, Hollister SJ.

Tissue Eng Part C Methods. 2013 Jul;19(7):507-17. doi: 10.1089/ten.TEC.2012.0495. Epub 2013 Mar 11.

38.

Wrapping and dispersion of multiwalled carbon nanotubes improves electrical conductivity of protein-nanotube composite biomaterials.

Voge CM, Johns J, Raghavan M, Morris MD, Stegemann JP.

J Biomed Mater Res A. 2013 Jan;101(1):231-8. doi: 10.1002/jbm.a.34310. Epub 2012 Aug 3.

PMID:
22865813
39.

Noninvasive, quantitative, spatiotemporal characterization of mineralization in three-dimensional collagen hydrogels using high-resolution spectral ultrasound imaging.

Gudur M, Rao RR, Hsiao YS, Peterson AW, Deng CX, Stegemann JP.

Tissue Eng Part C Methods. 2012 Dec;18(12):935-46. doi: 10.1089/ten.TEC.2012.0180. Epub 2012 Jul 16.

40.

Matrix composition regulates three-dimensional network formation by endothelial cells and mesenchymal stem cells in collagen/fibrin materials.

Rao RR, Peterson AW, Ceccarelli J, Putnam AJ, Stegemann JP.

Angiogenesis. 2012 Jun;15(2):253-64. doi: 10.1007/s10456-012-9257-1. Epub 2012 Mar 2.

41.

Exogenous mineralization of cell-seeded and unseeded collagen-chitosan hydrogels using modified culture medium.

Rao RR, Jiao A, Kohn DH, Stegemann JP.

Acta Biomater. 2012 Apr;8(4):1560-5. doi: 10.1016/j.actbio.2012.01.001. Epub 2012 Jan 10. Erratum in: Acta Biomater. 2012 Jul;8(6):2417.

42.

Interstitial fluid flow and cyclic strain differentially regulate cardiac fibroblast activation via AT1R and TGF-β1.

Galie PA, Russell MW, Westfall MV, Stegemann JP.

Exp Cell Res. 2012 Jan 1;318(1):75-84. doi: 10.1016/j.yexcr.2011.10.008. Epub 2011 Oct 14.

43.

A linear, biphasic model incorporating a brinkman term to describe the mechanics of cell-seeded collagen hydrogels.

Galie PA, Spilker RL, Stegemann JP.

Ann Biomed Eng. 2011 Nov;39(11):2767-79. doi: 10.1007/s10439-011-0371-9. Epub 2011 Aug 6.

44.

Phase-separated chitosan-fibrin microbeads for cell delivery.

Chen Z, Wang L, Stegemann JP.

J Microencapsul. 2011;28(5):344-52. doi: 10.3109/02652048.2011.569764.

45.

Glyoxal crosslinking of cell-seeded chitosan/collagen hydrogels for bone regeneration.

Wang L, Stegemann JP.

Acta Biomater. 2011 Jun;7(6):2410-7. doi: 10.1016/j.actbio.2011.02.029. Epub 2011 Feb 21.

46.

Reduced serum content and increased matrix stiffness promote the cardiac myofibroblast transition in 3D collagen matrices.

Galie PA, Westfall MV, Stegemann JP.

Cardiovasc Pathol. 2011 Nov-Dec;20(6):325-33. doi: 10.1016/j.carpath.2010.10.001. Epub 2011 Feb 8.

47.

Carbon nanotubes in neural interfacing applications.

Voge CM, Stegemann JP.

J Neural Eng. 2011 Feb;8(1):011001. doi: 10.1088/1741-2560/8/1/011001. Epub 2011 Jan 19. Review.

PMID:
21245526
48.

Simultaneous application of interstitial flow and cyclic mechanical strain to a three-dimensional cell-seeded hydrogel.

Galie PA, Stegemann JP.

Tissue Eng Part C Methods. 2011 May;17(5):527-36. doi: 10.1089/ten.TEC.2010.0547. Epub 2011 Feb 3.

49.

Gelatin microspheres crosslinked with genipin for local delivery of growth factors.

Solorio L, Zwolinski C, Lund AW, Farrell MJ, Stegemann JP.

J Tissue Eng Regen Med. 2010 Oct;4(7):514-23. doi: 10.1002/term.267.

50.

Thermogelling chitosan and collagen composite hydrogels initiated with beta-glycerophosphate for bone tissue engineering.

Wang L, Stegemann JP.

Biomaterials. 2010 May;31(14):3976-85. doi: 10.1016/j.biomaterials.2010.01.131. Epub 2010 Feb 18.

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