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Daratumumab in Sensitized Kidney Transplantation: Potentials and Limitations of Experimental and Clinical Use.

Kwun J, Matignon M, Manook M, Guendouz S, Audard V, Kheav D, Poullot E, Gautreau C, Ezekian B, Bodez D, Damy T, Faivre L, Menouch D, Yoon J, Park J, Belhadj K, Chen D, Bilewski AM, Yi JS, Collins B, Stegall M, Farris AB, Knechtle S, Grimbert P.

J Am Soc Nephrol. 2019 Jul;30(7):1206-1219. doi: 10.1681/ASN.2018121254. Epub 2019 Jun 21.


Using computer-assisted morphometrics of 5-year biopsies to identify biomarkers of late renal allograft loss.

Denic A, Morales MC, Park WD, Smith BH, Kremers WK, Alexander MP, Cosio FG, Rule AD, Stegall MD.

Am J Transplant. 2019 Apr 4. doi: 10.1111/ajt.15380. [Epub ahead of print]


Safety and efficacy of eculizumab in the prevention of antibody-mediated rejection in living-donor kidney transplant recipients requiring desensitization therapy: A randomized trial.

Marks WH, Mamode N, Montgomery RA, Stegall MD, Ratner LE, Cornell LD, Rowshani AT, Colvin RB, Dain B, Boice JA, Glotz D; C10-001 Study Group.

Am J Transplant. 2019 Mar 19. doi: 10.1111/ajt.15364. [Epub ahead of print]


The Relationship Between Frailty and Decreased Physical Performance With Death on the Kidney Transplant Waiting List.

Lorenz EC, Cosio FG, Bernard SL, Bogard SD, Bjerke BR, Geissler EN, Hanna SW, Kremers WK, Cheng Y, Stegall MD, Cheville AL, LeBrasseur NK.

Prog Transplant. 2019 Jun;29(2):108-114. doi: 10.1177/1526924819835803. Epub 2019 Mar 17.


Use of Eculizumab for Active Antibody-Mediated Rejection that Occurs Early Post-Kidney Transplantation: A Consecutive Series of 15 Cases.

Tan EK, Bentall AJ, Dean PG, Shaheen MF, Stegall MD, Schinstock CA.

Transplantation. 2019 Feb 19. doi: 10.1097/TP.0000000000002639. [Epub ahead of print]


Modeling graft loss in patients with donor-specific antibody at baseline using the Birmingham-Mayo (BirMay) predictor: Implications for clinical trials.

Bentall A, Smith BH, Gonzales MM, Bonner K, Park WD, Cornell LD, Dean PG, Schinstock CA, Borrows R, Lefaucheur C, Loupy A, Stegall MD.

Am J Transplant. 2019 Aug;19(8):2274-2283. doi: 10.1111/ajt.15312. Epub 2019 Mar 13.


Patient experience after kidney transplant: a conceptual framework of treatment burden.

Lorenz EC, Egginton JS, Stegall MD, Cheville AL, Heilman RL, Nair SS, Mai ML, Eton DT.

J Patient Rep Outcomes. 2019 Jan 30;3(1):8. doi: 10.1186/s41687-019-0095-4.


Larger nephron size, low nephron number, and nephrosclerosis on biopsy as predictors of kidney function after donating a kidney.

Issa N, Vaughan LE, Denic A, Kremers WK, Chakkera HA, Park WD, Matas AJ, Taler SJ, Stegall MD, Augustine JJ, Rule AD.

Am J Transplant. 2019 Jul;19(7):1989-1998. doi: 10.1111/ajt.15259. Epub 2019 Feb 1.


Factors at de novo donor-specific antibody initial detection associated with allograft loss: a multicenter study.

Schinstock CA, Dadhania DM, Everly MJ, Smith B, Gandhi M, Farkash E, Sharma VK, Samaniego-Picota M, Stegall MD.

Transpl Int. 2019 May;32(5):502-515. doi: 10.1111/tri.13395. Epub 2019 Feb 8.


Routine Stenting of Extravesical Ureteroneocystostomy in Kidney Transplantation: A Systematic Review and Meta-analysis.

Abrol N, Dean PG, Prieto M, Stegall MD, Taner T.

Transplant Proc. 2018 Dec;50(10):3397-3404. doi: 10.1016/j.transproceed.2018.06.041. Epub 2018 Jun 30.


The importance of drug safety and tolerability in the development of new immunosuppressive therapy for transplant recipients: The Transplant Therapeutics Consortium's position statement.

Stegall MD, Troy Somerville K, Everly MJ, Mannon RB, Gaber AO, First MR, Agashivala N, Perez V, Newell KA, Morris RE, Sudan D, Romero K, Eremenco S, Mattera M, Spear N, Porter AC, O'Doherty I.

Am J Transplant. 2019 Mar;19(3):625-632. doi: 10.1111/ajt.15214. Epub 2019 Jan 23.


Long-term Immunosuppression Adherence After Kidney Transplant and Relationship to Allograft Histology.

Lorenz EC, Smith BH, Cosio FG, Schinstock CA, Shah ND, Groehler PN, Verdick JS, Park WD, Stegall MD.

Transplant Direct. 2018 Sep 7;4(10):e392. doi: 10.1097/TXD.0000000000000824. eCollection 2018 Oct.


Long-term outcomes of eculizumab-treated positive crossmatch recipients: Allograft survival, histologic findings, and natural history of the donor-specific antibodies.

Schinstock CA, Bentall AJ, Smith BH, Cornell LD, Everly M, Gandhi MJ, Stegall MD.

Am J Transplant. 2019 Jun;19(6):1671-1683. doi: 10.1111/ajt.15175. Epub 2018 Dec 15.


Comparison of high glomerular filtration rate thresholds for identifying hyperfiltration.

Chakkera HA, Denic A, Kremers WK, Stegall MD, Larson JJ, Ravipati H, Taler SJ, Lieske JC, Lerman LO, Augustine JJ, Rule AD.

Nephrol Dial Transplant. 2018 Nov 6. doi: 10.1093/ndt/gfy332. [Epub ahead of print]


A method to reduce variability in scoring antibody-mediated rejection in renal allografts: implications for clinical trials - a retrospective study.

Smith B, Cornell LD, Smith M, Cortese C, Geiger X, Alexander MP, Ryan M, Park W, Morales Alvarez MC, Schinstock C, Kremers W, Stegall M.

Transpl Int. 2019 Feb;32(2):173-183. doi: 10.1111/tri.13340. Epub 2018 Oct 2.


Obesity and Metabolic Syndrome in Kidney Transplantation: The Role of Dietary Fructose and Systemic Endotoxemia.

Chan W, Smith B, Stegall M, Borrows R.

Transplantation. 2019 Jan;103(1):191-201. doi: 10.1097/TP.0000000000002424.


Identifying Barriers to Preemptive Kidney Transplantation in a Living Donor Transplant Cohort.

Helmick RA, Jay CL, Price BA, Dean PG, Stegall MD.

Transplant Direct. 2018 Mar 20;4(4):e356. doi: 10.1097/TXD.0000000000000773. eCollection 2018 Apr.


Donor-specific hypo-responsiveness occurs in simultaneous liver-kidney transplant recipients after the first year.

Taner T, Gustafson MP, Hansen MJ, Park WD, Bornschlegl S, Dietz AB, Stegall MD.

Kidney Int. 2018 Jun;93(6):1465-1474. doi: 10.1016/j.kint.2018.01.022. Epub 2018 Apr 12.


De novo donor-specific antibody following BK nephropathy: The incidence and association with antibody-mediated rejection.

Cheungpasitporn W, Kremers WK, Lorenz E, Amer H, Cosio FG, Stegall MD, Gandhi MJ, Schinstock CA.

Clin Transplant. 2018 Mar;32(3):e13194. doi: 10.1111/ctr.13194. Epub 2018 Feb 11.


The Banff 2017 Kidney Meeting Report: Revised diagnostic criteria for chronic active T cell-mediated rejection, antibody-mediated rejection, and prospects for integrative endpoints for next-generation clinical trials.

Haas M, Loupy A, Lefaucheur C, Roufosse C, Glotz D, Seron D, Nankivell BJ, Halloran PF, Colvin RB, Akalin E, Alachkar N, Bagnasco S, Bouatou Y, Becker JU, Cornell LD, van Huyen JPD, Gibson IW, Kraus ES, Mannon RB, Naesens M, Nickeleit V, Nickerson P, Segev DL, Singh HK, Stegall M, Randhawa P, Racusen L, Solez K, Mengel M.

Am J Transplant. 2018 Feb;18(2):293-307. doi: 10.1111/ajt.14625. Epub 2018 Jan 21.


Comparison Between Total IgG, C1q, and C3d Single Antigen Bead Assays in Detecting Class I Complement-Binding Anti-HLA Antibodies.

Moreno Gonzales MA, Mitema DG, Smith BH, Schinstock CA, Stegall MD, Wakefield LL, Henderson NA, DeGoey SR, Kreuter JD, Gandhi MJ.

Transplant Proc. 2017 Nov;49(9):2031-2035. doi: 10.1016/j.transproceed.2017.09.040.


Hospital readmissions following HLA-incompatible live donor kidney transplantation: A multi-center study.

Orandi BJ, Luo X, King EA, Garonzik-Wang JM, Bae S, Montgomery RA, Stegall MD, Jordan SC, Oberholzer J, Dunn TB, Ratner LE, Kapur S, Pelletier RP, Roberts JP, Melcher ML, Singh P, Sudan DL, Posner MP, El-Amm JM, Shapiro R, Cooper M, Lipkowitz GS, Rees MA, Marsh CL, Sankari BR, Gerber DA, Nelson PW, Wellen J, Bozorgzadeh A, Osama Gaber A, Segev DL.

Am J Transplant. 2018 Mar;18(3):650-658. doi: 10.1111/ajt.14472. Epub 2017 Sep 23.


Renal Allograft Histology at 10 Years After Transplantation in the Tacrolimus Era: Evidence of Pervasive Chronic Injury.

Stegall MD, Cornell LD, Park WD, Smith BH, Cosio FG.

Am J Transplant. 2018 Jan;18(1):180-188. doi: 10.1111/ajt.14431. Epub 2017 Aug 18.


The Incremental Cost of Incompatible Living Donor Kidney Transplantation: A National Cohort Analysis.

Axelrod D, Lentine KL, Schnitzler MA, Luo X, Xiao H, Orandi BJ, Massie A, Garonzik-Wang J, Stegall MD, Jordan SC, Oberholzer J, Dunn TB, Ratner LE, Kapur S, Pelletier RP, Roberts JP, Melcher ML, Singh P, Sudan DL, Posner MP, El-Amm JM, Shapiro R, Cooper M, Lipkowitz GS, Rees MA, Marsh CL, Sankari BR, Gerber DA, Nelson PW, Wellen J, Bozorgzadeh A, Osama Gaber A, Montgomery RA, Segev DL.

Am J Transplant. 2017 Dec;17(12):3123-3130. doi: 10.1111/ajt.14392. Epub 2017 Jul 21.


Pancreas transplantation.

Dean PG, Kukla A, Stegall MD, Kudva YC.

BMJ. 2017 Apr 3;357:j1321. doi: 10.1136/bmj.j1321. Review.


Relationship between pre-transplant physical function and outcomes after kidney transplant.

Lorenz EC, Cheville AL, Amer H, Kotajarvi BR, Stegall MD, Petterson TM, Kremers WK, Cosio FG, LeBrasseur NK.

Clin Transplant. 2017 May;31(5). doi: 10.1111/ctr.12952. Epub 2017 Apr 17. Erratum in: Clin Transplant. 2017 Aug;31(8):.


Impact of CXCR4/CXCL12 Blockade on Normal Plasma Cells In Vivo.

Moore N, Moreno Gonzales M, Bonner K, Smith B, Park W, Stegall M.

Am J Transplant. 2017 Jun;17(6):1663-1669. doi: 10.1111/ajt.14236. Epub 2017 Mar 22.


Unique molecular changes in kidney allografts after simultaneous liver-kidney compared with solitary kidney transplantation.

Taner T, Park WD, Stegall MD.

Kidney Int. 2017 May;91(5):1193-1202. doi: 10.1016/j.kint.2016.12.016. Epub 2017 Feb 21.


Clinical Trials for Immunosuppression in Transplantation: The Case for Reform and Change in Direction.

OʼConnell PJ, Kuypers DR, Mannon RB, Abecassis M, Chadban SJ, Gill JS, Murphy B, Nickerson PW, Schold JD, Stock PG, Seron D, Alloway RR, Bromberg JS, Budde K, Jordan SC, Legendre C, Lefaucheur C, Sarwall M, Segev DL, Stegall MD, Tullius SG, Wong G, Woodle ES, Ascher N, Morris RE.

Transplantation. 2017 Jul;101(7):1527-1534. doi: 10.1097/TP.0000000000001648.


Kidney Transplant With Low Levels of DSA or Low Positive B-Flow Crossmatch: An Underappreciated Option for Highly Sensitized Transplant Candidates.

Schinstock CA, Gandhi M, Cheungpasitporn W, Mitema D, Prieto M, Dean P, Cornell L, Cosio F, Stegall M.

Transplantation. 2017 Oct;101(10):2429-2439. doi: 10.1097/TP.0000000000001619.


Effects of Aspirin Therapy on Ultrasound-Guided Renal Allograft Biopsy Bleeding Complications.

Baffour FI, Hickson LJ, Stegall MD, Dean PG, Gunderson TM, Atwell TD, Kurup AN, Schmitz JJ, Park WD, Schmit GD.

J Vasc Interv Radiol. 2017 Feb;28(2):188-194. doi: 10.1016/j.jvir.2016.10.021. Epub 2016 Dec 16.


The Value of Protocol Biopsies to Identify Patients With De Novo Donor-Specific Antibody at High Risk for Allograft Loss.

Schinstock CA, Cosio F, Cheungpasitporn W, Dadhania DM, Everly MJ, Samaniego-Picota MD, Cornell L, Stegall MD.

Am J Transplant. 2017 Jun;17(6):1574-1584. doi: 10.1111/ajt.14161. Epub 2017 Jan 25.


Why do we have the kidney allocation system we have today? A history of the 2014 kidney allocation system.

Stegall MD, Stock PG, Andreoni K, Friedewald JJ, Leichtman AB.

Hum Immunol. 2017 Jan;78(1):4-8. doi: 10.1016/j.humimm.2016.08.008. Epub 2016 Aug 21.


Survival Benefit in Older Patients Associated With Earlier Transplant With High KDPI Kidneys.

Jay CL, Washburn K, Dean PG, Helmick RA, Pugh JA, Stegall MD.

Transplantation. 2017 Apr;101(4):867-872. doi: 10.1097/TP.0000000000001405.


32 Doses of Bortezomib for Desensitization Is Not Well Tolerated and Is Associated With Only Modest Reductions in Anti-HLA Antibody.

Moreno Gonzales MA, Gandhi MJ, Schinstock CA, Moore NA, Smith BH, Braaten NY, Stegall MD.

Transplantation. 2017 Jun;101(6):1222-1227. doi: 10.1097/TP.0000000000001330.


Early subclinical inflammation correlates with outcomes in positive crossmatch kidney allografts.

Dean PG, Park WD, Cornell LD, Schinstock CA, Stegall MD.

Clin Transplant. 2016 Aug;30(8):925-33. doi: 10.1111/ctr.12766. Epub 2016 Jun 22.


Liver Allograft Provides Immunoprotection for the Cardiac Allograft in Combined Heart-Liver Transplantation.

Wong TW, Gandhi MJ, Daly RC, Kushwaha SS, Pereira NL, Rosen CB, Stegall MD, Heimbach JK, Taner T.

Am J Transplant. 2016 Dec;16(12):3522-3531. doi: 10.1111/ajt.13870. Epub 2016 Jun 24.


Interpreting Anti-HLA Antibody Testing Data: A Practical Guide for Physicians.

Schinstock CA, Gandhi MJ, Stegall MD.

Transplantation. 2016 Aug;100(8):1619-28. doi: 10.1097/TP.0000000000001203. Review.


Survival Benefit with Kidney Transplants from HLA-Incompatible Live Donors.

Orandi BJ, Luo X, Massie AB, Garonzik-Wang JM, Lonze BE, Ahmed R, Van Arendonk KJ, Stegall MD, Jordan SC, Oberholzer J, Dunn TB, Ratner LE, Kapur S, Pelletier RP, Roberts JP, Melcher ML, Singh P, Sudan DL, Posner MP, El-Amm JM, Shapiro R, Cooper M, Lipkowitz GS, Rees MA, Marsh CL, Sankari BR, Gerber DA, Nelson PW, Wellen J, Bozorgzadeh A, Gaber AO, Montgomery RA, Segev DL.

N Engl J Med. 2016 Mar 10;374(10):940-50. doi: 10.1056/NEJMoa1508380.


Predicting Individual Renal Allograft Outcomes Using Risk Models with 1-Year Surveillance Biopsy and Alloantibody Data.

Gonzales MM, Bentall A, Kremers WK, Stegall MD, Borrows R.

J Am Soc Nephrol. 2016 Oct;27(10):3165-3174. doi: 10.1681/ASN.2015070811. Epub 2016 Mar 9.


Decreased chronic cellular and antibody-mediated injury in the kidney following simultaneous liver-kidney transplantation.

Taner T, Heimbach JK, Rosen CB, Nyberg SL, Park WD, Stegall MD.

Kidney Int. 2016 Apr;89(4):909-17. doi: 10.1016/j.kint.2015.10.016. Epub 2016 Jan 23.


Detection and Clinical Patterns of Nephron Hypertrophy and Nephrosclerosis Among Apparently Healthy Adults.

Denic A, Alexander MP, Kaushik V, Lerman LO, Lieske JC, Stegall MD, Larson JJ, Kremers WK, Vrtiska TJ, Chakkera HA, Poggio ED, Rule AD.

Am J Kidney Dis. 2016 Jul;68(1):58-67. doi: 10.1053/j.ajkd.2015.12.029. Epub 2016 Feb 6.


Underutilization of Timely Kidney Transplants in Those With Living Donors.

Sakhuja A, Naik A, Amer H, Cibrik D, Eikstadt R, Schold JD, Stegall MD.

Am J Transplant. 2016 Mar;16(3):1007-14. doi: 10.1111/ajt.13592. Epub 2016 Feb 4.


Developing New Immunosuppression for the Next Generation of Transplant Recipients: The Path Forward.

Stegall MD, Morris RE, Alloway RR, Mannon RB.

Am J Transplant. 2016 Apr;16(4):1094-101. doi: 10.1111/ajt.13582. Epub 2016 Jan 5.


Reassessing Preemptive Kidney Transplantation in the United States: Are We Making Progress?

Jay CL, Dean PG, Helmick RA, Stegall MD.

Transplantation. 2016 May;100(5):1120-7. doi: 10.1097/TP.0000000000000944.


Computational Biology: Modeling Chronic Renal Allograft Injury.

Stegall MD, Borrows R.

Front Immunol. 2015 Aug 3;6:385. doi: 10.3389/fimmu.2015.00385. eCollection 2015. Review.


Changing Kidney Allograft Histology Early Posttransplant: Prognostic Implications of 1-Year Protocol Biopsies.

Cosio FG, El Ters M, Cornell LD, Schinstock CA, Stegall MD.

Am J Transplant. 2016 Jan;16(1):194-203. doi: 10.1111/ajt.13423. Epub 2015 Aug 14.


Intravitreal Antivascular Endothelial Growth Factor Therapy May Induce Proteinuria and Antibody Mediated Injury in Renal Allografts.

Cheungpasitporn W, Chebib FT, Cornell LD, Brodin ML, Nasr SH, Schinstock CA, Stegall MD, Amer H.

Transplantation. 2015 Nov;99(11):2382-6. doi: 10.1097/TP.0000000000000750.


Adherence to a pedometer-based physical activity intervention following kidney transplant and impact on metabolic parameters.

Lorenz EC, Amer H, Dean PG, Stegall MD, Cosio FG, Cheville AL.

Clin Transplant. 2015 Jun;29(6):560-8. doi: 10.1111/ctr.12553. Epub 2015 May 26.


Positive crossmatch kidney transplant recipients treated with eculizumab: outcomes beyond 1 year.

Cornell LD, Schinstock CA, Gandhi MJ, Kremers WK, Stegall MD.

Am J Transplant. 2015 May;15(5):1293-302. doi: 10.1111/ajt.13168. Epub 2015 Mar 2.

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