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Items: 50

1.

Loop-Mediated Isothermal Amplification (LAMP) for Rapid Detection and Quantification of Dehalococcoides Biomarker Genes in Commercial Reductive Dechlorinating Cultures KB-1 and SDC-9.

Kanitkar YH, Stedtfeld RD, Steffan RJ, Hashsham SA, Cupples AM.

Appl Environ Microbiol. 2016 Jan 8;82(6):1799-1806. doi: 10.1128/AEM.03660-15.

2.

Indole trimers with antibacterial activity against Gram-positive organisms produced using combinatorial biocatalysis.

McClay K, Mehboob S, Yu J, Santarsiero BD, Deng J, Cook JL, Jeong H, Johnson ME, Steffan RJ.

AMB Express. 2015 Dec;5(1):125. doi: 10.1186/s13568-015-0125-4. Epub 2015 Jun 26.

3.

DNA extraction-free quantification of Dehalococcoides spp. in groundwater using a hand-held device.

Stedtfeld RD, Stedtfeld TM, Kronlein M, Seyrig G, Steffan RJ, Cupples AM, Hashsham SA.

Environ Sci Technol. 2014 Dec 2;48(23):13855-63.

PMID:
25360694
4.

Detection of Dehalococcoides spp. by peptide nucleic acid fluorescent in situ hybridization.

Danko AS, Fontenete SJ, de Aquino Leite D, Leitão PO, Almeida C, Schaefer CE, Vainberg S, Steffan RJ, Azevedo NF.

J Mol Microbiol Biotechnol. 2014;24(3):142-9. doi: 10.1159/000362790. Epub 2014 Jun 26.

PMID:
24970105
5.

Environmental biotechnology.

Steffan RJ, Ramos JL.

Curr Opin Biotechnol. 2013 Jun;24(3):421-2. doi: 10.1016/j.copbio.2013.04.002. Epub 2013 May 1. No abstract available.

PMID:
23642786
6.

Biodegradation of tetrahydrofuran and 1,4-dioxane by soluble diiron monooxygenase in Pseudonocardia sp. strain ENV478.

Masuda H, McClay K, Steffan RJ, Zylstra GJ.

J Mol Microbiol Biotechnol. 2012;22(5):312-6. doi: 10.1159/000343817. Epub 2012 Nov 6.

PMID:
23147387
7.

Characterization of three propane-inducible oxygenases in Mycobacterium sp. strain ENV421.

Masuda H, McClay K, Steffan RJ, Zylstra GJ.

Lett Appl Microbiol. 2012 Sep;55(3):175-81. doi: 10.1111/j.1472-765X.2012.03290.x. Epub 2012 Jul 31.

8.

Anaerobic biodegradation of iso-butanol and ethanol and their relative effects on BTEX biodegradation in aquifer materials.

Schaefer CE, Yang X, Pelz O, Tsao DT, Streger SH, Steffan RJ.

Chemosphere. 2010 Nov;81(9):1111-7. doi: 10.1016/j.chemosphere.2010.09.002. Epub 2010 Sep 27.

PMID:
20875669
9.

Aerobic biodegradation of iso-butanol and ethanol and their relative effects on BTEX biodegradation in aquifer materials.

Schaefer CE, Yang X, Pelz O, Tsao DT, Streger SH, Steffan RJ.

Chemosphere. 2010 Nov;81(9):1104-10. doi: 10.1016/j.chemosphere.2010.09.003. Epub 2010 Sep 26.

PMID:
20875664
10.

Bioaugmentation for treatment of dense non-aqueous phase liquid in fractured sandstone blocks.

Schaefer CE, Towne RM, Vainberg S, McCray JE, Steffan RJ.

Environ Sci Technol. 2010 Jul 1;44(13):4958-64. doi: 10.1021/es1002428.

PMID:
20524648
11.

Evaluation of a peat moss plus soybean oil (PMSO) technology for reducing explosive residue transport to groundwater at military training ranges under field conditions.

Fuller ME, Schaefer CE, Steffan RJ.

Chemosphere. 2009 Nov;77(8):1076-83. doi: 10.1016/j.chemosphere.2009.08.044. Epub 2009 Sep 17.

PMID:
19765798
12.

Large-scale production of bacterial consortia for remediation of chlorinated solvent-contaminated groundwater.

Vainberg S, Condee CW, Steffan RJ.

J Ind Microbiol Biotechnol. 2009 Sep;36(9):1189-97. doi: 10.1007/s10295-009-0600-5. Epub 2009 Jun 12.

PMID:
19521729
13.

Transformation of RDX and other energetic compounds by xenobiotic reductases XenA and XenB.

Fuller ME, McClay K, Hawari J, Paquet L, Malone TE, Fox BG, Steffan RJ.

Appl Microbiol Biotechnol. 2009 Sep;84(3):535-44. doi: 10.1007/s00253-009-2024-6. Epub 2009 May 20.

14.

LXR ligand lowers LDL cholesterol in primates, is lipid neutral in hamster, and reduces atherosclerosis in mouse.

Quinet EM, Basso MD, Halpern AR, Yates DW, Steffan RJ, Clerin V, Resmini C, Keith JC, Berrodin TJ, Feingold I, Zhong W, Hartman HB, Evans MJ, Gardell SJ, DiBlasio-Smith E, Mounts WM, LaVallie ER, Wrobel J, Nambi P, Vlasuk GP.

J Lipid Res. 2009 Dec;50(12):2358-70. doi: 10.1194/jlr.M900037-JLR200. Epub 2009 Mar 24.

15.

Bioaugmentation for chlorinated ethenes using Dehalococcoides sp.: comparison between batch and column experiments.

Schaefer CE, Condee CW, Vainberg S, Steffan RJ.

Chemosphere. 2009 Apr;75(2):141-8. doi: 10.1016/j.chemosphere.2008.12.041. Epub 2009 Jan 25.

PMID:
19171368
16.

Biodegradation of bis(2-chloroethyl) ether by Xanthobacter sp. strain ENV481.

McClay K, Schaefer CE, Vainberg S, Steffan RJ.

Appl Environ Microbiol. 2007 Nov;73(21):6870-5. Epub 2007 Sep 14.

17.

Biodegradation of ether pollutants by Pseudonocardia sp. strain ENV478.

Vainberg S, McClay K, Masuda H, Root D, Condee C, Zylstra GJ, Steffan RJ.

Appl Environ Microbiol. 2006 Aug;72(8):5218-24.

18.

Control of chronic inflammation with pathway selective estrogen receptor ligands.

Steffan RJ, Matelan E, Ashwell MA, Moore WJ, Solvibile WR, Trybulski E, Chadwick CC, Chippari S, Kenney T, Winneker RC, Eckert A, Borges-Marcucci L, Adelman SJ, Xu Z, Mosyak L, Harnish DC.

Curr Top Med Chem. 2006;6(2):103-11. Review.

PMID:
16454762
19.

Synthesis and activity of a new class of pathway-selective estrogen receptor ligands: hydroxybenzoyl-3,4-dihydroquinoxalin-2(1H)-ones.

Mahaney PE, Webb MB, Ye F, Sabatucci JP, Steffan RJ, Chadwick CC, Harnish DC, Trybulski EJ.

Bioorg Med Chem. 2006 May 15;14(10):3455-66. Epub 2006 Jan 19.

PMID:
16427291
20.

The activity of pathway-selective estrogen receptor ligands in experimental septic shock.

Opal SM, Palardy JE, Cristofaro P, Parejo N, Jhung JW, Keith JC Jr, Chippari S, Caggiano TJ, Steffan RJ, Chadwick CC, Harnish DC.

Shock. 2005 Dec;24(6):535-40.

PMID:
16317384
21.

Pyridobenzodiazepines: a novel class of orally active, vasopressin V2 receptor selective agonists.

Failli AA, Shumsky JS, Steffan RJ, Caggiano TJ, Williams DK, Trybulski EJ, Ning X, Lock Y, Tanikella T, Hartmann D, Chan PS, Park CH.

Bioorg Med Chem Lett. 2006 Feb 15;16(4):954-9. Epub 2005 Nov 15.

PMID:
16297621
22.
23.

The utility of pathway selective estrogen receptor ligands that inhibit nuclear factor-kappa B transcriptional activity in models of rheumatoid arthritis.

Keith JC Jr, Albert LM, Leathurby Y, Follettie M, Wang L, Borges-Marcucci L, Chadwick CC, Steffan RJ, Harnish DC.

Arthritis Res Ther. 2005;7(3):R427-38. Epub 2005 Feb 21.

24.

Identification of pathway-selective estrogen receptor ligands that inhibit NF-kappaB transcriptional activity.

Chadwick CC, Chippari S, Matelan E, Borges-Marcucci L, Eckert AM, Keith JC Jr, Albert LM, Leathurby Y, Harris HA, Bhat RA, Ashwell M, Trybulski E, Winneker RC, Adelman SJ, Steffan RJ, Harnish DC.

Proc Natl Acad Sci U S A. 2005 Feb 15;102(7):2543-8. Epub 2005 Feb 7.

25.

Synthesis and activity of substituted 4-(indazol-3-yl)phenols as pathway-selective estrogen receptor ligands useful in the treatment of rheumatoid arthritis.

Steffan RJ, Matelan E, Ashwell MA, Moore WJ, Solvibile WR, Trybulski E, Chadwick CC, Chippari S, Kenney T, Eckert A, Borges-Marcucci L, Keith JC, Xu Z, Mosyak L, Harnish DC.

J Med Chem. 2004 Dec 16;47(26):6435-8.

PMID:
15588074
26.

Enhancing the attenuation of explosives in surface soils at military facilities: combined sorption and biodegradation.

Fuller ME, Hatzinger PB, Rungmakol D, Schuster RL, Steffan RJ.

Environ Toxicol Chem. 2004 Feb;23(2):313-24.

PMID:
14982377
27.

Enhancing the attenuation of explosives in surface soils at military facilities: sorption-desorption isotherms.

Hatzinger PB, Fuller ME, Rungmakol D, Schuster RL, Steffan RJ.

Environ Toxicol Chem. 2004 Feb;23(2):306-12.

PMID:
14982376
28.

Novel substituted 4-aminomethylpiperidines as potent and selective human beta3-agonists. Part 2: arylethanolaminomethylpiperidines.

Steffan RJ, Ashwell MA, Solvibile WR, Matelan E, Largis E, Han S, Tillet J, Mulvey R.

Bioorg Med Chem Lett. 2002 Oct 21;12(20):2963-7.

PMID:
12270184
29.

Novel substituted 4-aminomethylpiperidines as potent and selective human beta3-agonists. Part 1: aryloxypropanolaminomethylpiperidines.

Steffan RJ, Ashwell MA, Solvibile WR, Matelan E, Largis E, Han S, Tillet J, Mulvey R.

Bioorg Med Chem Lett. 2002 Oct 21;12(20):2957-61.

PMID:
12270183
30.

Biodegradation of methyl tert-butyl ether by a pure bacterial culture.

Hatzinger PB, McClay K, Vainberg S, Tugusheva M, Condee CW, Steffan RJ.

Appl Environ Microbiol. 2001 Dec;67(12):5601-7.

31.

Optimized expression and purification of toluene 4-monooxygenase hydroxylase.

Studts JM, Mitchell KH, Pikus JD, McClay K, Steffan RJ, Fox BG.

Protein Expr Purif. 2000 Oct;20(1):58-65.

PMID:
11035951
32.

Toluene monooxygenase-catalyzed epoxidation of alkenes.

McClay K, Fox BG, Steffan RJ.

Appl Environ Microbiol. 2000 May;66(5):1877-82.

33.

Adaptive response to cold temperatures and characterization of cspA in Salmonella typhimurium LT2.

Horton AJ, Hak KM, Steffan RJ, Foster JW, Bej AK.

Antonie Van Leeuwenhoek. 2000 Jan;77(1):13-20.

PMID:
10696873
34.

Threonine 201 in the diiron enzyme toluene 4-monooxygenase is not required for catalysis.

Pikus JD, Mitchell KH, Studts JM, McClay K, Steffan RJ, Fox BG.

Biochemistry. 2000 Feb 1;39(4):791-9.

PMID:
10651645
35.

Adaptive response to cold temperatures in Vibrio vulnificus.

Bryan PJ, Steffan RJ, DePaola A, Foster JW, Bej AK.

Curr Microbiol. 1999 Mar;38(3):168-75.

PMID:
9922468
36.

Detection and classification of hyperfine-shifted 1H, 2H, and 15N resonances of the Rieske ferredoxin component of toluene 4-monooxygenase.

Xia B, Pikus JD, Xia W, McClay K, Steffan RJ, Chae YK, Westler WM, Markley JL, Fox BG.

Biochemistry. 1999 Jan 12;38(2):727-39.

PMID:
9888813
37.

Growth, survival and characterization of cspA in Salmonella enteritidis following cold shock.

Jeffreys AG, Hak KM, Steffan RJ, Foster JW, Bej AK.

Curr Microbiol. 1998 Jan;36(1):29-35.

PMID:
9405743
38.
39.

Changes in the regiospecificity of aromatic hydroxylation produced by active site engineering in the diiron enzyme toluene 4-monooxygenase.

Pikus JD, Studts JM, McClay K, Steffan RJ, Fox BG.

Biochemistry. 1997 Aug 5;36(31):9283-9.

PMID:
9280437
40.

Chloroform mineralization by toluene-oxidizing bacteria.

McClay K, Fox BG, Steffan RJ.

Appl Environ Microbiol. 1996 Aug;62(8):2716-22.

41.

Recombinant toluene-4-monooxygenase: catalytic and Mössbauer studies of the purified diiron and rieske components of a four-protein complex.

Pikus JD, Studts JM, Achim C, Kauffmann KE, Münck E, Steffan RJ, McClay K, Fox BG.

Biochemistry. 1996 Jul 16;35(28):9106-19.

PMID:
8703915
42.
43.

Inducible cell lysis system for the study of natural transformation and environmental fate of DNA released by cell death.

Kloos DU, Strätz M, Güttler A, Steffan RJ, Timmis KN.

J Bacteriol. 1994 Dec;176(23):7352-61.

44.

Designing microorganisms for the treatment of toxic wastes.

Timmis KN, Steffan RJ, Unterman R.

Annu Rev Microbiol. 1994;48:525-57. Review.

PMID:
7826017
45.

A nonimmunosuppressive triene-modified rapamycin analog is a potent inhibitor of peptidyl prolyl cis-trans isomerase.

Ocain TD, Longhi D, Steffan RJ, Caccese RG, Sehgal SN.

Biochem Biophys Res Commun. 1993 May 14;192(3):1340-6.

PMID:
7685167
46.

Polymerase chain reaction: applications in environmental microbiology.

Steffan RJ, Atlas RM.

Annu Rev Microbiol. 1991;45:137-61. Review. No abstract available.

PMID:
1741613
47.

Detection of coliform bacteria in water by polymerase chain reaction and gene probes.

Bej AK, Steffan RJ, DiCesare J, Haff L, Atlas RM.

Appl Environ Microbiol. 1990 Feb;56(2):307-14.

48.

Recovery of DNA from soils and sediments.

Steffan RJ, Goksøyr J, Bej AK, Atlas RM.

Appl Environ Microbiol. 1988 Dec;54(12):2908-15.

49.
50.

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