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Items: 20


Generation and function of progenitor T cells from StemRegenin-1-expanded CD34+ human hematopoietic progenitor cells.

Singh J, Chen ELY, Xing Y, Stefanski HE, Blazar BR, Zúñiga-Pflücker JC.

Blood Adv. 2019 Oct 22;3(20):2934-2948. doi: 10.1182/bloodadvances.2018026575.


Patient-reported quality of life after tisagenlecleucel infusion in children and young adults with relapsed or refractory B-cell acute lymphoblastic leukaemia: a global, single-arm, phase 2 trial.

Laetsch TW, Myers GD, Baruchel A, Dietz AC, Pulsipher MA, Bittencourt H, Buechner J, De Moerloose B, Davis KL, Nemecek E, Driscoll T, Mechinaud F, Boissel N, Rives S, Bader P, Peters C, Sabnis HS, Grupp SA, Yanik GA, Hiramatsu H, Stefanski HE, Rasouliyan L, Yi L, Shah S, Zhang J, Harris AC.

Lancet Oncol. 2019 Dec;20(12):1710-1718. doi: 10.1016/S1470-2045(19)30493-0. Epub 2019 Oct 9.


Thymic Epithelial Cell Support of Thymopoiesis Does Not Require Klotho.

Xing Y, Smith MJ, Goetz CA, McElmurry RT, Parker SL, Min D, Hollander GA, Weinberg KI, Tolar J, Stefanski HE, Blazar BR.

J Immunol. 2018 Dec 1;201(11):3320-3328. doi: 10.4049/jimmunol.1800670. Epub 2018 Oct 29.


Despite high levels of expression in thymic epithelial cells, miR-181a1 and miR-181b1 are not required for thymic development.

Stefanski HE, Xing Y, Taylor PA, Maio S, Henao-Meija J, Williams A, Flavell RA, Hollander GA, Blazar BR.

PLoS One. 2018 Jun 27;13(6):e0198871. doi: 10.1371/journal.pone.0198871. eCollection 2018.


A novel approach to improve immune effector responses post transplant by restoration of CCL21 expression.

Stefanski HE, Jonart L, Goren E, Mulé JJ, Blazar BR.

PLoS One. 2018 Apr 4;13(4):e0193461. doi: 10.1371/journal.pone.0193461. eCollection 2018.


Tisagenlecleucel in Children and Young Adults with B-Cell Lymphoblastic Leukemia.

Maude SL, Laetsch TW, Buechner J, Rives S, Boyer M, Bittencourt H, Bader P, Verneris MR, Stefanski HE, Myers GD, Qayed M, De Moerloose B, Hiramatsu H, Schlis K, Davis KL, Martin PL, Nemecek ER, Yanik GA, Peters C, Baruchel A, Boissel N, Mechinaud F, Balduzzi A, Krueger J, June CH, Levine BL, Wood P, Taran T, Leung M, Mueller KT, Zhang Y, Sen K, Lebwohl D, Pulsipher MA, Grupp SA.

N Engl J Med. 2018 Feb 1;378(5):439-448. doi: 10.1056/NEJMoa1709866.


T cell progenitor therapy-facilitated thymopoiesis depends upon thymic input and continued thymic microenvironment interaction.

Smith MJ, Reichenbach DK, Parker SL, Riddle MJ, Mitchell J, Osum KC, Mohtashami M, Stefanski HE, Fife BT, Bhandoola A, Hogquist KA, Holländer GA, Zúñiga-Pflücker JC, Tolar J, Blazar BR.

JCI Insight. 2017 May 18;2(10). pii: 92056. doi: 10.1172/jci.insight.92056. eCollection 2017 May 18.


Type 2 innate lymphoid cells treat and prevent acute gastrointestinal graft-versus-host disease.

Bruce DW, Stefanski HE, Vincent BG, Dant TA, Reisdorf S, Bommiasamy H, Serody DA, Wilson JE, McKinnon KP, Shlomchik WD, Armistead PM, Ting JPY, Woosley JT, Blazar BR, Zaiss DMW, McKenzie ANJ, Coghill JM, Serody JS.

J Clin Invest. 2017 May 1;127(5):1813-1825. doi: 10.1172/JCI91816. Epub 2017 Apr 4.


Fatal Myocarditis Associated With HHV-6 Following Immunosuppression in Two Children.

Stefanski HE, Thibert KA, Pritchett J, Prusty BK, Wagner JE, Lund TC.

Pediatrics. 2016 Jan;137(1). doi: 10.1542/peds.2015-1352. Epub 2015 Dec 17.


In Vitro T-Cell Generation From Adult, Embryonic, and Induced Pluripotent Stem Cells: Many Roads to One Destination.

Smith MJ, Webber BR, Mohtashami M, Stefanski HE, Zúñiga-Pflücker JC, Blazar BR.

Stem Cells. 2015 Nov;33(11):3174-80. doi: 10.1002/stem.2115. Epub 2015 Aug 11. Review.


Early hematopoietic stem cell transplant is associated with favorable outcomes in children with MDS.

Smith AR, Christiansen EC, Wagner JE, Cao Q, MacMillan ML, Stefanski HE, Trotz BA, Burke MJ, Verneris MR.

Pediatr Blood Cancer. 2013 Apr;60(4):705-10. doi: 10.1002/pbc.24390. Epub 2012 Nov 14.


MicroRNAs control the maintenance of thymic epithelia and their competence for T lineage commitment and thymocyte selection.

Zuklys S, Mayer CE, Zhanybekova S, Stefanski HE, Nusspaumer G, Gill J, Barthlott T, Chappaz S, Nitta T, Dooley J, Nogales-Cadenas R, Takahama Y, Finke D, Liston A, Blazar BR, Pascual-Montano A, Holländer GA.

J Immunol. 2012 Oct 15;189(8):3894-904. doi: 10.4049/jimmunol.1200783. Epub 2012 Sep 12.


FTY720 markedly increases alloengraftment but does not eliminate host anti-donor T cells that cause graft rejection on its withdrawal.

Taylor PA, Kelly RM, Bade ND, Smith MJ, Stefanski HE, Blazar BR.

Biol Blood Marrow Transplant. 2012 Sep;18(9):1341-52. doi: 10.1016/j.bbmt.2012.06.007. Epub 2012 Jun 19.


Mouse Ly49G2+ NK cells dominate early responses during both immune reconstitution and activation independently of MHC.

Barao I, Alvarez M, Ames E, Orr MT, Stefanski HE, Blazar BR, Lanier LL, Anderson SK, Redelman D, Murphy WJ.

Blood. 2011 Jun 30;117(26):7032-41. doi: 10.1182/blood-2010-11-316653. Epub 2011 Apr 15.


Short-term inhibition of p53 combined with keratinocyte growth factor improves thymic epithelial cell recovery and enhances T-cell reconstitution after murine bone marrow transplantation.

Kelly RM, Goren EM, Taylor PA, Mueller SN, Stefanski HE, Osborn MJ, Scott HS, Komarova EA, Gudkov AV, Holländer GA, Blazar BR.

Blood. 2010 Feb 4;115(5):1088-97. doi: 10.1182/blood-2009-05-223198. Epub 2009 Dec 4.


A spontaneous CD8 T cell-dependent autoimmune disease to an antigen expressed under the human keratin 14 promoter.

McGargill MA, Mayerova D, Stefanski HE, Koehn B, Parke EA, Jameson SC, Panoskaltsis-Mortari A, Hogquist KA.

J Immunol. 2002 Aug 15;169(4):2141-7.


A low affinity TCR ligand restores positive selection of CD8+ T cells in vivo.

Stefanski HE, Mayerova D, Jameson SC, Hogquist KA.

J Immunol. 2001 Jun 1;166(11):6602-7. Erratum in: J Immunol 2001 Jul 1;167(1):593.


Positive selection is limited by available peptide-dependent MHC conformations.

Stefanski HE, Jameson SC, Hogquist KA.

J Immunol. 2000 Apr 1;164(7):3519-26.


Identification of mimotopes for the H4 minor histocompatibility antigen.

Strausbauch MA, Nevala WK, Roopenian DC, Stefanski HE, Wettstein PJ.

Int Immunol. 1998 Apr;10(4):421-34.


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