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Items: 1 to 50 of 157

1.

Motor function and the probability of prodromal Parkinson's disease in older adults.

Maraki MI, Stefanis L, Yannakoulia M, Kosmidis MH, Xiromerisiou G, Dardiotis E, Hadjigeorgiou GM, Sakka P, Scarmeas N, Stamelou M.

Mov Disord. 2019 Jul 17. doi: 10.1002/mds.27792. [Epub ahead of print]

PMID:
31314148
2.

Serotonergic pathology and disease burden in the premotor and motor phase of A53T α-synuclein parkinsonism: a cross-sectional study.

Wilson H, Dervenoulas G, Pagano G, Koros C, Yousaf T, Picillo M, Polychronis S, Simitsi A, Giordano B, Chappell Z, Corcoran B, Stamelou M, Gunn RN, Pellecchia MT, Rabiner EA, Barone P, Stefanis L, Politis M.

Lancet Neurol. 2019 Aug;18(8):748-759. doi: 10.1016/S1474-4422(19)30140-1. Epub 2019 Jun 19.

PMID:
31229470
3.

MOG antibody-associated demyelinating disease mimicking typical multiple sclerosis: A case for expanding anti-MOG testing?

Breza M, Koutsis G, Tzartos JS, Velonakis G, Evangelopoulos ME, Tzanetakos D, Karagiorgou K, Angelopoulou G, Kasselimis D, Potagas C, Anagnostouli M, Stefanis L, Kilidireas C.

Mult Scler Relat Disord. 2019 Aug;33:67-69. doi: 10.1016/j.msard.2019.05.021. Epub 2019 May 28.

PMID:
31158804
4.

How is alpha-synuclein cleared from the cell?

Stefanis L, Emmanouilidou E, Pantazopoulou M, Kirik D, Vekrellis K, Tofaris GK.

J Neurochem. 2019 May 8. doi: 10.1111/jnc.14704. [Epub ahead of print] Review.

PMID:
31069800
5.

Endogenous oligodendroglial alpha-synuclein and TPPP/p25α orchestrate alpha-synuclein pathology in experimental multiple system atrophy models.

Mavroeidi P, Arvanitaki F, Karakitsou AK, Vetsi M, Kloukina I, Zweckstetter M, Giller K, Becker S, Sorrentino ZA, Giasson BI, Jensen PH, Stefanis L, Xilouri M.

Acta Neuropathol. 2019 Apr 22. doi: 10.1007/s00401-019-02014-y. [Epub ahead of print]

PMID:
31011860
6.

Autophagy dysfunction in peripheral blood mononuclear cells of Parkinson's disease patients.

Papagiannakis N, Xilouri M, Koros C, Simitsi AM, Stamelou M, Maniati M, Stefanis L.

Neurosci Lett. 2019 Jun 21;704:112-115. doi: 10.1016/j.neulet.2019.04.003. Epub 2019 Apr 4.

PMID:
30954606
7.

Higher probability of prodromal Parkinson disease is related to lower cognitive performance.

Bougea A, Maraki MI, Yannakoulia M, Stamelou M, Xiromerisiou G, Kosmidis MH, Ntanasi E, Dardiotis E, Hadjigeorgiou GM, Sakka P, Anastasiou CA, Stefanis L, Scarmeas N.

Neurology. 2019 May 7;92(19):e2261-e2272. doi: 10.1212/WNL.0000000000007453. Epub 2019 Apr 3.

PMID:
30944240
8.

Clinical and neuropathological differences between Parkinson's disease, Parkinson's disease dementia and dementia with Lewy bodies - current issues and future directions.

Walker L, Stefanis L, Attems J.

J Neurochem. 2019 Mar 20. doi: 10.1111/jnc.14698. [Epub ahead of print] Review.

PMID:
30892688
9.

Long Non-coding RNAs Associated With Neurodegeneration-Linked Genes Are Reduced in Parkinson's Disease Patients.

Elkouris M, Kouroupi G, Vourvoukelis A, Papagiannakis N, Kaltezioti V, Matsas R, Stefanis L, Xilouri M, Politis PK.

Front Cell Neurosci. 2019 Feb 22;13:58. doi: 10.3389/fncel.2019.00058. eCollection 2019.

10.

Plasma alpha-synuclein levels in patients with Parkinson's disease: a systematic review and meta-analysis.

Bougea A, Stefanis L, Paraskevas GP, Emmanouilidou E, Vekrelis K, Kapaki E.

Neurol Sci. 2019 May;40(5):929-938. doi: 10.1007/s10072-019-03738-1. Epub 2019 Feb 4.

PMID:
30715632
11.

Clinical, neuropsychological and imaging characteristics of Alzheimer's disease patients presenting as corticobasal syndrome.

Constantinides VC, Paraskevas GP, Efthymiopoulou E, Stefanis L, Kapaki E.

J Neurol Sci. 2019 Mar 15;398:142-147. doi: 10.1016/j.jns.2019.01.046. Epub 2019 Jan 29.

PMID:
30711771
12.

Quantifying apraxia and ophthalmokinetic abnormalities in patients with atypical Parkinsonism: A new way to differential diagnosis?

Constantinides VC, Paraskevas GP, Potagas C, Stefanis L, Kapaki E.

Parkinsonism Relat Disord. 2019 Apr;61:39-44. doi: 10.1016/j.parkreldis.2018.12.006. Epub 2018 Dec 12. No abstract available.

PMID:
30563744
13.

Impairment of chaperone-mediated autophagy affects neuronal homeostasis through altered expression of DJ-1 and CRMP-2 proteins.

Brekk OR, Makridakis M, Mavroeidi P, Vlahou A, Xilouri M, Stefanis L.

Mol Cell Neurosci. 2019 Mar;95:1-12. doi: 10.1016/j.mcn.2018.12.006. Epub 2018 Dec 15.

PMID:
30562574
14.

Frontotemporal dementia spectrum: first genetic screen in a Greek cohort.

Ramos EM, Koros C, Dokuru DR, Van Berlo V, Kroupis C, Wojta K, Wang Q, Andronas N, Matsi S, Beratis IN, Huang AY, Lee SE, Bonakis A, Florou-Hatziyiannidou C, Fragkiadaki S, Kontaxopoulou D, Agiomyrgiannakis D, Kamtsadeli V, Tsinia N, Papastefanopoulou V, Stamelou M, Miller BL, Stefanis L, Papatriantafyllou JD, Papageorgiou SG, Coppola G.

Neurobiol Aging. 2019 Mar;75:224.e1-224.e8. doi: 10.1016/j.neurobiolaging.2018.10.029. Epub 2018 Nov 3.

PMID:
30528349
15.

Age-dependent variation of female preponderance across different phenotypes of multiple sclerosis: A retrospective cross-sectional study.

Miclea A, Salmen A, Zoehner G, Diem L, Kamm CP, Chaloulos-Iakovidis P, Miclea M, Briner M, Kilidireas K, Stefanis L, Chan A, Evangelopoulos ME, Hoepner R.

CNS Neurosci Ther. 2019 Apr;25(4):527-531. doi: 10.1111/cns.13083. Epub 2018 Nov 8.

16.

A case of Alemtuzumab-induced neutropenia in multiple sclerosis in association with the expansion of large granular lymphocytes.

Vakrakou AG, Tzanetakos D, Valsami S, Grigoriou E, Psarra K, Tzartos J, Anagnostouli M, Andreadou E, Evangelopoulos ME, Koutsis G, Chrysovitsanou C, Gialafos E, Dimitrakopoulos A, Stefanis L, Kilidireas C.

BMC Neurol. 2018 Oct 29;18(1):178. doi: 10.1186/s12883-018-1183-4.

17.

Mediterranean diet adherence is related to reduced probability of prodromal Parkinson's disease.

Maraki MI, Yannakoulia M, Stamelou M, Stefanis L, Xiromerisiou G, Kosmidis MH, Dardiotis E, Hadjigeorgiou GM, Sakka P, Anastasiou CA, Simopoulou E, Scarmeas N.

Mov Disord. 2019 Jan;34(1):48-57. doi: 10.1002/mds.27489. Epub 2018 Oct 10.

PMID:
30306634
18.

123I-FP-CIT SPECT [(123) I-2β-carbomethoxy-3β-(4-iodophenyl)-N-(3-fluoropropyl) nortropane single photon emission computed tomography] Imaging in a p.A53T α-synuclein Parkinson's disease cohort versus Parkinson's disease.

Koros C, Simitsi A, Prentakis A, Beratis I, Papadimitriou D, Kontaxopoulou D, Fragkiadaki S, Papagiannakis N, Seibyl J, Marek K, Papageorgiou SG, Trapali XG, Stamelou M, Stefanis L.

Mov Disord. 2018 Nov;33(11):1734-1739. doi: 10.1002/mds.27451. Epub 2018 Oct 4.

PMID:
30288781
19.

Three new case reports of Arteriovenous malformation-related Amyotrophic Lateral Sclerosis.

Chondrogianni M, Bregianni M, Frantzeskaki F, Giamarellos-Bourboulis E, Anagnostou E, Kararizou E, Karadima G, Koutsis G, Moschovos C, Bonakis A, Stefanis L.

J Neurol Sci. 2018 Oct 15;393:58-62. doi: 10.1016/j.jns.2018.08.011. Epub 2018 Aug 9.

PMID:
30114551
20.

Neuropsychiatric symptoms and α-Synuclein profile of patients with Parkinson's disease dementia, dementia with Lewy bodies and Alzheimer's disease.

Bougea A, Stefanis L, Paraskevas GP, Emmanouilidou E, Efthymiopoulou E, Vekrelis K, Kapaki E.

J Neurol. 2018 Oct;265(10):2295-2301. doi: 10.1007/s00415-018-8992-7. Epub 2018 Aug 6.

PMID:
30083953
21.

Intrafamilial variability in a polish family harbouring a frameshift THAP1 mutation.

Stamelou M, Petrucci S, Ginevrino M, Pons R, Papagiannakis N, Stefanis L, Valente EM.

J Neurol Sci. 2018 May 15;388:158. doi: 10.1016/j.jns.2018.03.026. Epub 2018 Mar 16. No abstract available.

PMID:
29627013
22.

Identification of a prospective early motor progression cluster of Parkinson's disease: Data from the PPMI study.

Vavougios GD, Doskas T, Kormas C, Krogfelt KA, Zarogiannis SG, Stefanis L.

J Neurol Sci. 2018 Apr 15;387:103-108. doi: 10.1016/j.jns.2018.01.025. Epub 2018 Jan 31.

PMID:
29571843
23.

Modulation of β-glucocerebrosidase increases α-synuclein secretion and exosome release in mouse models of Parkinson's disease.

Papadopoulos VE, Nikolopoulou G, Antoniadou I, Karachaliou A, Arianoglou G, Emmanouilidou E, Sardi SP, Stefanis L, Vekrellis K.

Hum Mol Genet. 2018 May 15;27(10):1696-1710. doi: 10.1093/hmg/ddy075.

PMID:
29547959
24.

Phenotypic Characteristics in GBA-Associated Parkinson's Disease: A Study in a Greek Population.

Simitsi A, Koros C, Moraitou M, Papagiannakis N, Antonellou R, Bozi M, Angelopoulou E, Stamelou M, Michelakakis H, Stefanis L.

J Parkinsons Dis. 2018;8(1):101-105. doi: 10.3233/JPD-171221.

PMID:
29480223
25.

A motif within the armadillo repeat of Parkinson's-linked LRRK2 interacts with FADD to hijack the extrinsic death pathway.

Antoniou N, Vlachakis D, Memou A, Leandrou E, Valkimadi PE, Melachroinou K, Re DB, Przedborski S, Dauer WT, Stefanis L, Rideout HJ.

Sci Rep. 2018 Feb 22;8(1):3455. doi: 10.1038/s41598-018-21931-8.

26.

Selective cognitive impairment and hyposmia in p.A53T SNCA PD vs typical PD.

Koros C, Stamelou M, Simitsi A, Beratis I, Papadimitriou D, Papagiannakis N, Fragkiadaki S, Kontaxopoulou D, Papageorgiou SG, Stefanis L.

Neurology. 2018 Mar 6;90(10):e864-e869. doi: 10.1212/WNL.0000000000005063. Epub 2018 Feb 7.

PMID:
29438043
27.

Progressive striatonigral degeneration in a transgenic mouse model of multiple system atrophy: translational implications for interventional therapies.

Refolo V, Bez F, Polissidis A, Kuzdas-Wood D, Sturm E, Kamaratou M, Poewe W, Stefanis L, Angela Cenci M, Romero-Ramos M, Wenning GK, Stefanova N.

Acta Neuropathol Commun. 2018 Jan 3;6(1):2. doi: 10.1186/s40478-017-0504-y.

28.

The different faces of the p. A53T alpha-synuclein mutation: A screening of Greek patients with parkinsonism and/or dementia.

Breza M, Koutsis G, Karadima G, Potagas C, Kartanou C, Papageorgiou SG, Paraskevas GP, Kapaki E, Stefanis L, Panas M.

Neurosci Lett. 2018 Apr 13;672:136-139. doi: 10.1016/j.neulet.2017.12.015. Epub 2017 Dec 9.

PMID:
29233723
29.

Alpha-synuclein dimerization in erythrocytes of patients with genetic and non-genetic forms of Parkinson's Disease.

Papagiannakis N, Koros C, Stamelou M, Simitsi AM, Maniati M, Antonelou R, Papadimitriou D, Dermentzaki G, Moraitou M, Michelakakis H, Stefanis L.

Neurosci Lett. 2018 Apr 13;672:145-149. doi: 10.1016/j.neulet.2017.11.012. Epub 2017 Nov 10.

PMID:
29129675
30.

Clinical rating scale for pantothenate kinase-associated neurodegeneration: A pilot study.

Darling A, Tello C, Martí MJ, Garrido C, Aguilera-Albesa S, Tomás Vila M, Gastón I, Madruga M, González Gutiérrez L, Ramos Lizana J, Pujol M, Gavilán Iglesias T, Tustin K, Lin JP, Zorzi G, Nardocci N, Martorell L, Lorenzo Sanz G, Gutiérrez F, García PJ, Vela L, Hernández Lahoz C, Ortigoza Escobar JD, Martí Sánchez L, Moreira F, Coelho M, Correia Guedes L, Castro Caldas A, Ferreira J, Pires P, Costa C, Rego P, Magalhães M, Stamelou M, Cuadras Pallejà D, Rodríguez-Blazquez C, Martínez-Martín P, Lupo V, Stefanis L, Pons R, Espinós C, Temudo T, Pérez Dueñas B.

Mov Disord. 2017 Nov;32(11):1620-1630. doi: 10.1002/mds.27129. Epub 2017 Aug 28.

PMID:
28845923
31.

Toll-like receptor 4 stimulation with monophosphoryl lipid A ameliorates motor deficits and nigral neurodegeneration triggered by extraneuronal α-synucleinopathy.

Venezia S, Refolo V, Polissidis A, Stefanis L, Wenning GK, Stefanova N.

Mol Neurodegener. 2017 Jul 4;12(1):52. doi: 10.1186/s13024-017-0195-7.

32.

Genetics of Parkinson's Disease: Genotype-Phenotype Correlations.

Koros C, Simitsi A, Stefanis L.

Int Rev Neurobiol. 2017;132:197-231. doi: 10.1016/bs.irn.2017.01.009. Epub 2017 Mar 1. Review.

PMID:
28554408
33.

ADCY5-related movement disorders: Frequency, disease course and phenotypic variability in a cohort of paediatric patients.

Carecchio M, Mencacci NE, Iodice A, Pons R, Panteghini C, Zorzi G, Zibordi F, Bonakis A, Dinopoulos A, Jankovic J, Stefanis L, Bhatia KP, Monti V, R'Bibo L, Veneziano L, Garavaglia B, Fusco C, Wood N, Stamelou M, Nardocci N.

Parkinsonism Relat Disord. 2017 Aug;41:37-43. doi: 10.1016/j.parkreldis.2017.05.004. Epub 2017 May 10.

34.

Duration of paroxysmal atrial fibrillation in cryptogenic stroke is not associated with stroke severity and early outcomes.

Liantinioti C, Tympas K, Katsanos AH, Parissis J, Chondrogianni M, Zompola C, Papadimitropoulos G, Ioakeimidis M, Triantafyllou S, Roussopoulou A, Voumvourakis K, Lekakis J, Filippatos G, Stefanis L, Tsivgoulis G.

J Neurol Sci. 2017 May 15;376:191-195. doi: 10.1016/j.jns.2017.03.038. Epub 2017 Mar 23. Review.

PMID:
28431610
35.

Defective synaptic connectivity and axonal neuropathology in a human iPSC-based model of familial Parkinson's disease.

Kouroupi G, Taoufik E, Vlachos IS, Tsioras K, Antoniou N, Papastefanaki F, Chroni-Tzartou D, Wrasidlo W, Bohl D, Stellas D, Politis PK, Vekrellis K, Papadimitriou D, Stefanis L, Bregestovski P, Hatzigeorgiou AG, Masliah E, Matsas R.

Proc Natl Acad Sci U S A. 2017 May 2;114(18):E3679-E3688. doi: 10.1073/pnas.1617259114. Epub 2017 Apr 17.

36.

Frontotemporal dementia as the presenting phenotype of p.A53T mutation carriers in the alpha-synuclein gene.

Bougea A, Koros C, Stamelou M, Simitsi A, Papagiannakis N, Antonelou R, Papadimitriou D, Breza M, Tasios K, Fragkiadaki S, Geronicola Trapali X, Bourbouli M, Koutsis G, Papageorgiou SG, Kapaki E, Paraskevas GP, Stefanis L.

Parkinsonism Relat Disord. 2017 Feb;35:82-87. doi: 10.1016/j.parkreldis.2016.12.002. Epub 2016 Dec 6.

PMID:
28012952
37.

Activation of FADD-Dependent Neuronal Death Pathways as a Predictor of Pathogenicity for LRRK2 Mutations.

Melachroinou K, Leandrou E, Valkimadi PE, Memou A, Hadjigeorgiou G, Stefanis L, Rideout HJ.

PLoS One. 2016 Nov 10;11(11):e0166053. doi: 10.1371/journal.pone.0166053. eCollection 2016.

38.

Evaluation of the interaction between LRRK2 and PARK16 loci in determining risk of Parkinson's disease: analysis of a large multicenter study.

Wang L, Heckman MG, Aasly JO, Annesi G, Bozi M, Chung SJ, Clarke C, Crosiers D, Eckstein G, Garraux G, Hadjigeorgiou GM, Hattori N, Jeon B, Kim YJ, Kubo M, Lesage S, Lin JJ, Lynch T, Lichtner P, Mellick GD, Mok V, Morrison KE, Quattrone A, Satake W, Silburn PA, Stefanis L, Stockton JD, Tan EK, Toda T, Brice A, Van Broeckhoven C, Uitti RJ, Wirdefeldt K, Wszolek Z, Xiromerisiou G, Maraganore DM, Gasser T, Krüger R, Farrer MJ, Ross OA, Sharma M; GEOPD Consortium.

Neurobiol Aging. 2017 Jan;49:217.e1-217.e4. doi: 10.1016/j.neurobiolaging.2016.09.022. Epub 2016 Oct 6.

39.

Impairment of chaperone-mediated autophagy induces dopaminergic neurodegeneration in rats.

Xilouri M, Brekk OR, Polissidis A, Chrysanthou-Piterou M, Kloukina I, Stefanis L.

Autophagy. 2016 Nov;12(11):2230-2247. Epub 2016 Aug 19.

40.

Analysis of a founder mutation in the TH gene in a cohort of greek patients with Parkinson's disease.

Pons R, Kekou K, Antonellou R, Svingou M, Kanavakis E, Stefanis L.

Mov Disord. 2016 Nov;31(11):1753-1754. doi: 10.1002/mds.26807. Epub 2016 Sep 26. No abstract available.

PMID:
27666733
41.

Chaperone mediated autophagy in aging: Starve to prosper.

Xilouri M, Stefanis L.

Ageing Res Rev. 2016 Dec;32:13-21. doi: 10.1016/j.arr.2016.07.001. Epub 2016 Jul 30. Review.

PMID:
27484893
42.

Motor and Nonmotor Features of Carriers of the p.A53T Alpha-Synuclein Mutation: A Longitudinal Study.

Papadimitriou D, Antonelou R, Miligkos M, Maniati M, Papagiannakis N, Bostantjopoulou S, Leonardos A, Koros C, Simitsi A, Papageorgiou SG, Kapaki E, Alcalay RN, Papadimitriou A, Athanassiadou A, Stamelou M, Stefanis L.

Mov Disord. 2016 Aug;31(8):1226-30. doi: 10.1002/mds.26615. Epub 2016 Mar 29.

PMID:
27028329
43.

Complex Effects of the ZSCAN21 Transcription Factor on Transcriptional Regulation of α-Synuclein in Primary Neuronal Cultures and in Vivo.

Dermentzaki G, Paschalidis N, Politis PK, Stefanis L.

J Biol Chem. 2016 Apr 15;291(16):8756-72. doi: 10.1074/jbc.M115.704973. Epub 2016 Feb 23.

44.

Autophagy and Alpha-Synuclein: Relevance to Parkinson's Disease and Related Synucleopathies.

Xilouri M, Brekk OR, Stefanis L.

Mov Disord. 2016 Feb;31(2):178-92. doi: 10.1002/mds.26477. Epub 2016 Jan 27. Review.

PMID:
26813776
45.

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).

Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, Agnello M, Agostinis P, Aguilar PV, Aguirre-Ghiso J, Airoldi EM, Ait-Si-Ali S, Akematsu T, Akporiaye ET, Al-Rubeai M, Albaiceta GM, Albanese C, Albani D, Albert ML, Aldudo J, Algül H, Alirezaei M, Alloza I, Almasan A, Almonte-Beceril M, Alnemri ES, Alonso C, Altan-Bonnet N, Altieri DC, Alvarez S, Alvarez-Erviti L, Alves S, Amadoro G, Amano A, Amantini C, Ambrosio S, Amelio I, Amer AO, Amessou M, Amon A, An Z, Anania FA, Andersen SU, Andley UP, Andreadi CK, Andrieu-Abadie N, Anel A, Ann DK, Anoopkumar-Dukie S, Antonioli M, Aoki H, Apostolova N, Aquila S, Aquilano K, Araki K, Arama E, Aranda A, Araya J, Arcaro A, Arias E, Arimoto H, Ariosa AR, Armstrong JL, Arnould T, Arsov I, Asanuma K, Askanas V, Asselin E, Atarashi R, Atherton SS, Atkin JD, Attardi LD, Auberger P, Auburger G, Aurelian L, Autelli R, Avagliano L, Avantaggiati ML, Avrahami L, Awale S, Azad N, Bachetti T, Backer JM, Bae DH, Bae JS, Bae ON, Bae SH, Baehrecke EH, Baek SH, Baghdiguian S, Bagniewska-Zadworna A, Bai H, Bai J, Bai XY, Bailly Y, Balaji KN, Balduini W, Ballabio A, Balzan R, Banerjee R, Bánhegyi G, Bao H, Barbeau B, Barrachina MD, Barreiro E, Bartel B, Bartolomé A, Bassham DC, Bassi MT, Bast RC Jr, Basu A, Batista MT, Batoko H, Battino M, Bauckman K, Baumgarner BL, Bayer KU, Beale R, Beaulieu JF, Beck GR Jr, Becker C, Beckham JD, Bédard PA, Bednarski PJ, Begley TJ, Behl C, Behrends C, Behrens GM, Behrns KE, Bejarano E, Belaid A, Belleudi F, Bénard G, Berchem G, Bergamaschi D, Bergami M, Berkhout B, Berliocchi L, Bernard A, Bernard M, Bernassola F, Bertolotti A, Bess AS, Besteiro S, Bettuzzi S, Bhalla S, Bhattacharyya S, Bhutia SK, Biagosch C, Bianchi MW, Biard-Piechaczyk M, Billes V, Bincoletto C, Bingol B, Bird SW, Bitoun M, Bjedov I, Blackstone C, Blanc L, Blanco GA, Blomhoff HK, Boada-Romero E, Böckler S, Boes M, 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