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Items: 1 to 50 of 298

1.

Trends in Obesity Among Low-Income Young Children.

Stefan N, Schulze MB.

JAMA. 2019 Nov 5;322(17):1713-1714. doi: 10.1001/jama.2019.14220. No abstract available.

PMID:
31688877
2.

The WW1 Domain Enhances Autoinhibition in Smurf Ubiquitin Ligases.

Ruetalo N, Anders S, Stollmaier C, Jäckl M, Schütz-Stoffregen MC, Stefan N, Wolf C, Wiesner S.

J Mol Biol. 2019 Oct 16. pii: S0022-2836(19)30573-X. doi: 10.1016/j.jmb.2019.09.018. [Epub ahead of print]

PMID:
31628949
3.

Empagliflozin Effectively Lowers Liver Fat Content in Well-Controlled Type 2 Diabetes: A Randomized, Double-Blind, Phase 4, Placebo-Controlled Trial.

Kahl S, Gancheva S, Straßburger K, Herder C, Machann J, Katsuyama H, Kabisch S, Henkel E, Kopf S, Lagerpusch M, Kantartzis K, Kupriyanova Y, Markgraf D, van Gemert T, Knebel B, Wolkersdorfer MF, Kuss O, Hwang JH, Bornstein SR, Kasperk C, Stefan N, Pfeiffer A, Birkenfeld AL, Roden M.

Diabetes Care. 2019 Sep 20. pii: dc190641. doi: 10.2337/dc19-0641. [Epub ahead of print]

PMID:
31540903
4.

AMPK subunits harbor largely non-overlapping genetic determinants for body fat mass, glucose- and cholesterol metabolism.

Randrianarisoa E, Lehn-Stefan A, Krier J, Böhm A, Heni M, Hrabě de Angelis M, Fritsche A, Häring HU, Stefan N, Staiger H.

J Clin Endocrinol Metab. 2019 Sep 12. pii: dgz020. doi: 10.1210/clinem/dgz020. [Epub ahead of print]

PMID:
31512724
5.

Associations of short stature and components of height with incidence of type 2 diabetes: mediating effects of cardiometabolic risk factors.

Wittenbecher C, Kuxhaus O, Boeing H, Stefan N, Schulze MB.

Diabetologia. 2019 Dec;62(12):2211-2221. doi: 10.1007/s00125-019-04978-8. Epub 2019 Sep 9.

6.

Pulsed Laser Fabrication of TiO2 Buffer Layers for Dye Sensitized Solar Cells.

Lungu J, Socol G, Stan GE, Ştefan N, Luculescu C, Georgescu A, Popescu-Pelin G, Prodan G, Gîrţu MA, Mihăilescu IN.

Nanomaterials (Basel). 2019 May 15;9(5). pii: E746. doi: 10.3390/nano9050746.

7.

Metabolomic Characteristics of Fatty Pancreas.

Jaghutriz BA, Wagner R, Heni M, Lehmann R, Machann J, Stefan N, Häring HU, Fritsche A.

Exp Clin Endocrinol Diabetes. 2019 May 16. doi: 10.1055/a-0896-8671. [Epub ahead of print]

PMID:
31096268
8.

Effect of SGLT2 inhibitors on body composition, fluid status and renin-angiotensin-aldosterone system in type 2 diabetes: a prospective study using bioimpedance spectroscopy.

Schork A, Saynisch J, Vosseler A, Jaghutriz BA, Heyne N, Peter A, Häring HU, Stefan N, Fritsche A, Artunc F.

Cardiovasc Diabetol. 2019 Apr 5;18(1):46. doi: 10.1186/s12933-019-0852-y.

9.

Sex-Specific Associations of Testosterone With Metabolic Traits.

Lutz SZ, Wagner R, Fritsche L, Peter A, Rettig I, Willmann C, Fehlert E, Martus P, Todenhöfer T, Stefan N, Fritsche A, Häring HU, Heni M.

Front Endocrinol (Lausanne). 2019 Mar 13;10:90. doi: 10.3389/fendo.2019.00090. eCollection 2019.

10.

Visceral Adiposity Index as an Independent Marker of Subclinical Atherosclerosis in Individuals Prone to Diabetes Mellitus.

Randrianarisoa E, Lehn-Stefan A, Hieronimus A, Rietig R, Fritsche A, Machann J, Balletshofer B, Häring HU, Stefan N, Rittig K.

J Atheroscler Thromb. 2019 Sep 1;26(9):821-834. doi: 10.5551/jat.47274. Epub 2019 Feb 19.

11.

Impact of diverse chemotherapeutic agents and external factors on activation of brown adipose tissue in a large patient collective.

Brendle C, Stefan N, Stef I, Ripkens S, Soekler M, la Fougère C, Nikolaou K, Pfannenberg C.

Sci Rep. 2019 Feb 13;9(1):1901. doi: 10.1038/s41598-018-37924-6.

12.

Potential effects of reduced red meat compared with increased fiber intake on glucose metabolism and liver fat content: a randomized and controlled dietary intervention study.

Willmann C, Heni M, Linder K, Wagner R, Stefan N, Machann J, Schulze MB, Joost HG, Häring HU, Fritsche A.

Am J Clin Nutr. 2019 Feb 1;109(2):288-296. doi: 10.1093/ajcn/nqy307.

PMID:
30721948
13.

Dietary Niacin Intake Predicts the Decrease of Liver Fat Content During a Lifestyle Intervention.

Linder K, Willmann C, Kantartzis K, Machann J, Schick F, Graf M, Kümmerle S, Häring HU, Fritsche A, Stefan N, Wagner R.

Sci Rep. 2019 Feb 4;9(1):1303. doi: 10.1038/s41598-018-38002-7.

14.

A Polygenic Risk Score of Lipolysis-Increasing Alleles Determines Visceral Fat Mass and Proinsulin Conversion.

Kempe-Teufel D, Machicao F, Machann J, Böhm A, Schick F, Fritsche A, Stefan N, Hrabě de Angelis M, Häring HU, Staiger H.

J Clin Endocrinol Metab. 2019 Apr 1;104(4):1090-1098. doi: 10.1210/jc.2018-02042.

PMID:
30649496
15.

[New aspects of nonalcoholic steatohepatitis].

Stefan N.

Internist (Berl). 2019 Feb;60(2):128-132. doi: 10.1007/s00108-018-0550-y. Review. German.

PMID:
30645665
16.

The Gly385(388)Arg Polymorphism of the FGFR4 Receptor Regulates Hepatic Lipogenesis Under Healthy Diet.

Lutz SZ, Hennige AM, Peter A, Kovarova M, Totsikas C, Machann J, Kröber SM, Sperl B, Schleicher E, Schick F, Heni M, Ullrich A, Häring HU, Stefan N.

J Clin Endocrinol Metab. 2019 Jun 1;104(6):2041-2053. doi: 10.1210/jc.2018-01573.

PMID:
30541128
17.

Genetic variation in TCF7L2 rs7903146 and history of GDM negatively and independently impact on diabetes-associated metabolic traits.

Fritsche L, Sarief M, Wagner R, Stefan N, Lehmann R, Häring HU, Grallert H, Fritsche A, Lechner A.

Diabetes Res Clin Pract. 2018 Dec;146:251-257. doi: 10.1016/j.diabres.2018.11.003. Epub 2018 Nov 10.

PMID:
30419301
18.

Genome-Wide and Abdominal MRI Data Provide Evidence That a Genetically Determined Favorable Adiposity Phenotype Is Characterized by Lower Ectopic Liver Fat and Lower Risk of Type 2 Diabetes, Heart Disease, and Hypertension.

Ji Y, Yiorkas AM, Frau F, Mook-Kanamori D, Staiger H, Thomas EL, Atabaki-Pasdar N, Campbell A, Tyrrell J, Jones SE, Beaumont RN, Wood AR, Tuke MA, Ruth KS, Mahajan A, Murray A, Freathy RM, Weedon MN, Hattersley AT, Hayward C, Machann J, Häring HU, Franks P, de Mutsert R, Pearson E, Stefan N, Frayling TM, Allebrandt KV, Bell JD, Blakemore AI, Yaghootkar H.

Diabetes. 2019 Jan;68(1):207-219. doi: 10.2337/db18-0708. Epub 2018 Oct 23.

19.

Non-alcoholic fatty liver disease: causes, diagnosis, cardiometabolic consequences, and treatment strategies.

Stefan N, Häring HU, Cusi K.

Lancet Diabetes Endocrinol. 2019 Apr;7(4):313-324. doi: 10.1016/S2213-8587(18)30154-2. Epub 2018 Aug 30. Review.

PMID:
30174213
20.

School-supervised use of a once-daily inhaled corticosteroid regimen: A cluster randomized trial.

Gerald JK, Fisher JM, Brown MA, Clemens CJ, Moore MA, Carvajal SC, Bryson D, Stefan N, Billheimer D, Gerald LB.

J Allergy Clin Immunol. 2019 Feb;143(2):755-764. doi: 10.1016/j.jaci.2018.06.048. Epub 2018 Aug 14.

21.

Transition from metabolic healthy to unhealthy phenotypes and association with cardiovascular disease risk across BMI categories in 90 257 women (the Nurses' Health Study): 30 year follow-up from a prospective cohort study.

Eckel N, Li Y, Kuxhaus O, Stefan N, Hu FB, Schulze MB.

Lancet Diabetes Endocrinol. 2018 Sep;6(9):714-724. doi: 10.1016/S2213-8587(18)30137-2. Epub 2018 May 31.

PMID:
29859908
22.

Single Nucleotide Polymorphisms in the G-Protein Coupled Receptor Kinase 5 (GRK5) Gene are associated with Plasma LDL-Cholesterol Levels in Humans.

Lutz SZ, Falcenberg M, Machicao F, Peter A, Kächele M, Randrianarisoa E, Lehn-Stefan A, Wagner R, Machann J, Schick F, Heni M, Ullrich A, Fritsche A, Stefan N, Häring HU, Staiger H, Kantartzis K.

Sci Rep. 2018 May 17;8(1):7745. doi: 10.1038/s41598-018-26055-7.

23.

Circulating Fetuin-A and Risk of Type 2 Diabetes: A Mendelian Randomization Analysis.

Kröger J, Meidtner K, Stefan N, Guevara M, Kerrison ND, Ardanaz E, Aune D, Boeing H, Dorronsoro M, Dow C, Fagherazzi G, Franks PW, Freisling H, Gunter MJ, Huerta JM, Kaaks R, Key TJ, Khaw KT, Krogh V, Kühn T, Mancini FR, Mattiello A, Nilsson PM, Olsen A, Overvad K, Palli D, Quirós JR, Rolandsson O, Sacerdote C, Sala N, Salamanca-Fernández E, Sluijs I, Spijkerman AMW, Tjonneland A, Tsilidis KK, Tumino R, van der Schouw YT, Forouhi NG, Sharp SJ, Langenberg C, Riboli E, Schulze MB, Wareham NJ.

Diabetes. 2018 Jun;67(6):1200-1205. doi: 10.2337/db17-1268. Epub 2018 Mar 9.

24.

Effects of resveratrol supplementation on liver fat content in overweight and insulin-resistant subjects: A randomized, double-blind, placebo-controlled clinical trial.

Kantartzis K, Fritsche L, Bombrich M, Machann J, Schick F, Staiger H, Kunz I, Schoop R, Lehn-Stefan A, Heni M, Peter A, Fritsche A, Häring HU, Stefan N.

Diabetes Obes Metab. 2018 Jul;20(7):1793-1797. doi: 10.1111/dom.13268. Epub 2018 Mar 22.

PMID:
29484808
25.

Nonalcoholic Fatty Liver Disease and Mortality.

Stefan N.

Clin Gastroenterol Hepatol. 2018 Jul;16(7):1043-1045. doi: 10.1016/j.cgh.2018.02.016. Epub 2018 Feb 21. No abstract available.

PMID:
29474973
26.

Periaortic Adipose Tissue Compared With Peribrachial Adipose Tissue Mass as Markers and Possible Modulators of Cardiometabolic Risk.

Randrianarisoa E, Stefan N, Fritsche A, Reis-Damaschk N, Hieronimus A, Balletshofer B, Machann J, Siegel-Axel D, Häring HU, Rittig K.

Angiology. 2018 Nov;69(10):854-860. doi: 10.1177/0003319718755581. Epub 2018 Feb 14. Erratum in: Angiology. 2019 Aug;70(7):677. Reis-Damaschk N [added].

PMID:
29444588
27.

Serine/threonine protein kinase 25 antisense oligonucleotide treatment reverses glucose intolerance, insulin resistance, and nonalcoholic fatty liver disease in mice.

Nuñez-Durán E, Aghajan M, Amrutkar M, Sütt S, Cansby E, Booten SL, Watt A, Ståhlman M, Stefan N, Häring HU, Staiger H, Borén J, Marschall HU, Mahlapuu M.

Hepatol Commun. 2017 Nov 20;2(1):69-83. doi: 10.1002/hep4.1128. eCollection 2018 Jan.

28.

The hepatokines fetuin-A and fetuin-B are upregulated in the state of hepatic steatosis and may differently impact on glucose homeostasis in humans.

Peter A, Kovarova M, Staiger H, Machann J, Schick F, Königsrainer A, Königsrainer I, Schleicher E, Fritsche A, Häring HU, Stefan N.

Am J Physiol Endocrinol Metab. 2018 Mar 1;314(3):E266-E273. doi: 10.1152/ajpendo.00262.2017. Epub 2017 Nov 14.

29.

Correlation of Brown Adipose Tissue with Other Body Fat Compartments and Patient Characteristics: A Retrospective Analysis in a Large Patient Cohort Using PET/CT.

Brendle C, Werner MK, Schmadl M, la Fougère C, Nikolaou K, Stefan N, Pfannenberg C.

Acad Radiol. 2018 Jan;25(1):102-110. doi: 10.1016/j.acra.2017.09.007. Epub 2017 Nov 3.

PMID:
29108812
30.

Elevated hepatic DPP4 activity promotes insulin resistance and non-alcoholic fatty liver disease.

Baumeier C, Schlüter L, Saussenthaler S, Laeger T, Rödiger M, Alaze SA, Fritsche L, Häring HU, Stefan N, Fritsche A, Schwenk RW, Schürmann A.

Mol Metab. 2017 Oct;6(10):1254-1263. doi: 10.1016/j.molmet.2017.07.016. Epub 2017 Aug 4.

31.

Metabolically healthy obesity: the low-hanging fruit in obesity treatment?

Stefan N, Häring HU, Schulze MB.

Lancet Diabetes Endocrinol. 2018 Mar;6(3):249-258. doi: 10.1016/S2213-8587(17)30292-9. Epub 2017 Sep 14. Review.

PMID:
28919065
32.

Non-alcoholic fatty liver disease and impaired proinsulin conversion as newly identified predictors of the long-term non-response to a lifestyle intervention for diabetes prevention: results from the TULIP study.

Schmid V, Wagner R, Sailer C, Fritsche L, Kantartzis K, Peter A, Heni M, Häring HU, Stefan N, Fritsche A.

Diabetologia. 2017 Dec;60(12):2341-2351. doi: 10.1007/s00125-017-4407-z. Epub 2017 Aug 24.

PMID:
28840257
33.

Metabolic crosstalk between fatty pancreas and fatty liver: effects on local inflammation and insulin secretion.

Gerst F, Wagner R, Kaiser G, Panse M, Heni M, Machann J, Bongers MN, Sartorius T, Sipos B, Fend F, Thiel C, Nadalin S, Königsrainer A, Stefan N, Fritsche A, Häring HU, Ullrich S, Siegel-Axel D.

Diabetologia. 2017 Nov;60(11):2240-2251. doi: 10.1007/s00125-017-4385-1. Epub 2017 Aug 8.

PMID:
28791439
34.

Causes, Characteristics, and Consequences of Metabolically Unhealthy Normal Weight in Humans.

Stefan N, Schick F, Häring HU.

Cell Metab. 2017 Aug 1;26(2):292-300. doi: 10.1016/j.cmet.2017.07.008. Review.

35.

DPP4 gene variation affects GLP-1 secretion, insulin secretion, and glucose tolerance in humans with high body adiposity.

Böhm A, Wagner R, Machicao F, Holst JJ, Gallwitz B, Stefan N, Fritsche A, Häring HU, Staiger H.

PLoS One. 2017 Jul 27;12(7):e0181880. doi: 10.1371/journal.pone.0181880. eCollection 2017.

36.

Genetic Predisposition to Abdominal Adiposity and Cardiometabolic Risk.

Schulze MB, Stefan N.

JAMA. 2017 Jun 13;317(22):2334. doi: 10.1001/jama.2017.5041. No abstract available.

PMID:
28609526
37.

Genetic determination of body fat distribution and the attributive influence on metabolism.

Fehlert E, Wagner R, Ketterer C, Böhm A, Machann J, Fritsche L, Machicao F, Schick F, Staiger H, Stefan N, Häring HU, Fritsche A, Heni M.

Obesity (Silver Spring). 2017 Jul;25(7):1277-1283. doi: 10.1002/oby.21874. Epub 2017 May 25.

38.

Intra- and interindividual variability of fatty acid unsaturation in six different human adipose tissue compartments assessed by 1 H-MRS in vivo at 3 T.

Machann J, Stefan N, Wagner R, Bongers M, Schleicher E, Fritsche A, Häring HU, Nikolaou K, Schick F.

NMR Biomed. 2017 Sep;30(9). doi: 10.1002/nbm.3744. Epub 2017 May 25.

PMID:
28543814
39.

The protective effect of human renal sinus fat on glomerular cells is reversed by the hepatokine fetuin-A.

Wagner R, Machann J, Guthoff M, Nawroth PP, Nadalin S, Saleem MA, Heyne N, Königsrainer A, Fend F, Schick F, Fritsche A, Stefan N, Häring HU, Schleicher E, Siegel-Axel DI.

Sci Rep. 2017 May 23;7(1):2261. doi: 10.1038/s41598-017-02210-4.

40.

Erratum to: A novel insulin sensitivity index particularly suitable to measure insulin sensitivity during gestation.

Wagner R, Fritsche L, Heni M, Fehlert E, Stefan N, Staiger H, Häring HU, Fritsche A.

Acta Diabetol. 2017 Jul;54(7):713-714. doi: 10.1007/s00592-017-1002-1. No abstract available.

PMID:
28534066
41.

Common variation in the sodium/glucose cotransporter 2 gene SLC5A2 does neither affect fasting nor glucose-suppressed plasma glucagon concentrations.

Ordelheide AM, Böhm A, Kempe-Teufel D, Wagner R, Machicao F, Heni M, Stefan N, Fritsche A, Häring HU, Staiger H.

PLoS One. 2017 May 4;12(5):e0177148. doi: 10.1371/journal.pone.0177148. eCollection 2017.

42.

Highly Potent, Anthracycline-based Antibody-Drug Conjugates Generated by Enzymatic, Site-specific Conjugation.

Stefan N, Gébleux R, Waldmeier L, Hell T, Escher M, Wolter FI, Grawunder U, Beerli RR.

Mol Cancer Ther. 2017 May;16(5):879-892. doi: 10.1158/1535-7163.MCT-16-0688. Epub 2017 Mar 3.

43.

Hypothalamic and Striatal Insulin Action Suppresses Endogenous Glucose Production and May Stimulate Glucose Uptake During Hyperinsulinemia in Lean but Not in Overweight Men.

Heni M, Wagner R, Kullmann S, Gancheva S, Roden M, Peter A, Stefan N, Preissl H, Häring HU, Fritsche A.

Diabetes. 2017 Jul;66(7):1797-1806. doi: 10.2337/db16-1380. Epub 2017 Feb 7.

44.

An extended fatty liver index to predict non-alcoholic fatty liver disease.

Kantartzis K, Rettig I, Staiger H, Machann J, Schick F, Scheja L, Gastaldelli A, Bugianesi E, Peter A, Schulze MB, Fritsche A, Häring HU, Stefan N.

Diabetes Metab. 2017 Jun;43(3):229-239. doi: 10.1016/j.diabet.2016.11.006. Epub 2017 Jan 12.

45.

Nonsuppressed Glucagon After Glucose Challenge as a Potential Predictor for Glucose Tolerance.

Wagner R, Hakaste LH, Ahlqvist E, Heni M, Machann J, Schick F, Van Obberghen E, Stefan N, Gallwitz B, Tuomi T, Häring HU, Groop L, Fritsche A.

Diabetes. 2017 May;66(5):1373-1379. doi: 10.2337/db16-0354. Epub 2016 Dec 16.

46.

The impact of insulin resistance on the kidney and vasculature.

Artunc F, Schleicher E, Weigert C, Fritsche A, Stefan N, Häring HU.

Nat Rev Nephrol. 2016 Dec;12(12):721-737. doi: 10.1038/nrneph.2016.145. Epub 2016 Oct 17. Review.

PMID:
27748389
47.

A novel insulin sensitivity index particularly suitable to measure insulin sensitivity during gestation.

Wagner R, Fritsche L, Heni M, Fehlert E, Stefan N, Staiger H, Häring HU, Fritsche A.

Acta Diabetol. 2016 Dec;53(6):1037-1044. doi: 10.1007/s00592-016-0930-5. Epub 2016 Oct 22. Erratum in: Acta Diabetol. 2017 Jul;54(7):713-714.

PMID:
27771766
48.

Structural and Magnetoresistive Properties of Nanometric Films Based on Iron and Chromium Oxides on the Si Substrate.

Smirnov AB, Kryvyi SB, Mulenko SA, Sadovnikova ML, Savkina RK, Stefan N.

Nanoscale Res Lett. 2016 Dec;11(1):467. Epub 2016 Oct 20.

49.

Genetic Variation in the 11β-hydroxysteroid-dehydrogenase 1 Gene Determines NAFLD and Visceral Obesity.

Lutz SZ, Peter A, Machicao F, Lamprinou A, Machann J, Schick F, Königsrainer I, Königsrainer A, Fritsche A, Staiger H, Häring HU, Stefan N, Kantartzis K.

J Clin Endocrinol Metab. 2016 Dec;101(12):4743-4751. Epub 2016 Oct 7.

PMID:
27715400
50.

Genome-Wide Association Study of the Modified Stumvoll Insulin Sensitivity Index Identifies BCL2 and FAM19A2 as Novel Insulin Sensitivity Loci.

Walford GA, Gustafsson S, Rybin D, Stančáková A, Chen H, Liu CT, Hong J, Jensen RA, Rice K, Morris AP, Mägi R, Tönjes A, Prokopenko I, Kleber ME, Delgado G, Silbernagel G, Jackson AU, Appel EV, Grarup N, Lewis JP, Montasser ME, Landenvall C, Staiger H, Luan J, Frayling TM, Weedon MN, Xie W, Morcillo S, Martínez-Larrad MT, Biggs ML, Chen YD, Corbaton-Anchuelo A, Færch K, Gómez-Zumaquero JM, Goodarzi MO, Kizer JR, Koistinen HA, Leong A, Lind L, Lindgren C, Machicao F, Manning AK, Martín-Núñez GM, Rojo-Martínez G, Rotter JI, Siscovick DS, Zmuda JM, Zhang Z, Serrano-Rios M, Smith U, Soriguer F, Hansen T, Jørgensen TJ, Linnenberg A, Pedersen O, Walker M, Langenberg C, Scott RA, Wareham NJ, Fritsche A, Häring HU, Stefan N, Groop L, O'Connell JR, Boehnke M, Bergman RN, Collins FS, Mohlke KL, Tuomilehto J, März W, Kovacs P, Stumvoll M, Psaty BM, Kuusisto J, Laakso M, Meigs JB, Dupuis J, Ingelsson E, Florez JC.

Diabetes. 2016 Oct;65(10):3200-11. doi: 10.2337/db16-0199. Epub 2016 Jul 14.

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