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Mismatch repair gene pathogenic germline variants in a population-based cohort of breast cancer.

Nguyen-Dumont T, Steen JA, Winship I, Park DJ, Pope BJ, Hammet F, Mahmoodi M, Tsimiklis H, Theys D, Clendenning M, Giles GG, Hopper JL, Southey MC.

Fam Cancer. 2020 Feb 14. doi: 10.1007/s10689-020-00164-7. [Epub ahead of print]


Cell-Type-Specific Profiling of Alternative Translation Identifies Regulated Protein Isoform Variation in the Mouse Brain.

Sapkota D, Lake AM, Yang W, Yang C, Wesseling H, Guise A, Uncu C, Dalal JS, Kraft AW, Lee JM, Sands MS, Steen JA, Dougherty JD.

Cell Rep. 2019 Jan 15;26(3):594-607.e7. doi: 10.1016/j.celrep.2018.12.077.


A Fast and Quantitative Method for Post-translational Modification and Variant Enabled Mapping of Peptides to Genomes.

Schlaffner CN, Pirklbauer GJ, Bender A, Steen JAJ, Choudhary JS.

J Vis Exp. 2018 May 22;(135). doi: 10.3791/57633.


Atmospheric trace gases support primary production in Antarctic desert surface soil.

Ji M, Greening C, Vanwonterghem I, Carere CR, Bay SK, Steen JA, Montgomery K, Lines T, Beardall J, van Dorst J, Snape I, Stott MB, Hugenholtz P, Ferrari BC.

Nature. 2017 Dec 21;552(7685):400-403. doi: 10.1038/nature25014. Epub 2017 Dec 6.


Chemogenomic analysis reveals key role for lysine acetylation in regulating Arc stability.

Lalonde J, Reis SA, Sivakumaran S, Holland CS, Wesseling H, Sauld JF, Alural B, Zhao WN, Steen JA, Haggarty SJ.

Nat Commun. 2017 Nov 21;8(1):1659. doi: 10.1038/s41467-017-01750-7.


Human Rights: Its Meaning and Practice in Social Work Field Settings.

Steen JA, Mann M, Restivo N, Mazany S, Chapple R.

Soc Work. 2017 Jan 1;62(1):9-17. doi: 10.1093/sw/sww075.


Human iPSC-Derived Neuronal Model of Tau-A152T Frontotemporal Dementia Reveals Tau-Mediated Mechanisms of Neuronal Vulnerability.

Silva MC, Cheng C, Mair W, Almeida S, Fong H, Biswas MHU, Zhang Z, Huang Y, Temple S, Coppola G, Geschwind DH, Karydas A, Miller BL, Kosik KS, Gao FB, Steen JA, Haggarty SJ.

Stem Cell Reports. 2016 Sep 13;7(3):325-340. doi: 10.1016/j.stemcr.2016.08.001. Epub 2016 Sep 1.


Phosphorylation-Induced Motor Shedding Is Required at Mitosis for Proper Distribution and Passive Inheritance of Mitochondria.

Chung JY, Steen JA, Schwarz TL.

Cell Rep. 2016 Aug 23;16(8):2142-2155. doi: 10.1016/j.celrep.2016.07.055. Epub 2016 Aug 11.


Tetanus toxin production is triggered by the transition from amino acid consumption to peptides.

Licona-Cassani C, Steen JA, Zaragoza NE, Moonen G, Moutafis G, Hodson MP, Power J, Nielsen LK, Marcellin E.

Anaerobe. 2016 Oct;41:113-124. doi: 10.1016/j.anaerobe.2016.07.006. Epub 2016 Aug 1.


FLEXITau: Quantifying Post-translational Modifications of Tau Protein in Vitro and in Human Disease.

Mair W, Muntel J, Tepper K, Tang S, Biernat J, Seeley WW, Kosik KS, Mandelkow E, Steen H, Steen JA.

Anal Chem. 2016 Apr 5;88(7):3704-14. doi: 10.1021/acs.analchem.5b04509. Epub 2016 Mar 7.


Doublecortin-Like Kinases Promote Neuronal Survival and Induce Growth Cone Reformation via Distinct Mechanisms.

Nawabi H, Belin S, Cartoni R, Williams PR, Wang C, Latremolière A, Wang X, Zhu J, Taub DG, Fu X, Yu B, Gu X, Woolf CJ, Liu JS, Gabel CV, Steen JA, He Z.

Neuron. 2015 Nov 18;88(4):704-19. doi: 10.1016/j.neuron.2015.10.005. Epub 2015 Oct 29.


Injury-induced decline of intrinsic regenerative ability revealed by quantitative proteomics.

Belin S, Nawabi H, Wang C, Tang S, Latremoliere A, Warren P, Schorle H, Uncu C, Woolf CJ, He Z, Steen JA.

Neuron. 2015 May 20;86(4):1000-1014. doi: 10.1016/j.neuron.2015.03.060. Epub 2015 Apr 30.


ST2249-MRSA-III: a second major recombinant methicillin-resistant Staphylococcus aureus clone causing healthcare infection in the 1970s.

Nimmo GR, Steen JA, Monecke S, Ehricht R, Slickers P, Thomas JC, Appleton S, Goering RV, Robinson DA, Coombs GW.

Clin Microbiol Infect. 2015 May;21(5):444-50. doi: 10.1016/j.cmi.2014.12.018. Epub 2015 Jan 28.


Ferrets exclusively synthesize Neu5Ac and express naturally humanized influenza A virus receptors.

Ng PS, Böhm R, Hartley-Tassell LE, Steen JA, Wang H, Lukowski SW, Hawthorne PL, Trezise AE, Coloe PJ, Grimmond SM, Haselhorst T, von Itzstein M, Paton AW, Paton JC, Jennings MP.

Nat Commun. 2014 Dec 17;5:5750. doi: 10.1038/ncomms6750.


Quantitative comparison of a human cancer cell surface proteome between interphase and mitosis.

Özlü N, Qureshi MH, Toyoda Y, Renard BY, Mollaoglu G, Özkan NE, Bulbul S, Poser I, Timm W, Hyman AA, Mitchison TJ, Steen JA.

EMBO J. 2015 Jan 13;34(2):251-65. doi: 10.15252/embj.201385162. Epub 2014 Dec 4.


Quantitative profiling of peptides from RNAs classified as noncoding.

Prabakaran S, Hemberg M, Chauhan R, Winter D, Tweedie-Cullen RY, Dittrich C, Hong E, Gunawardena J, Steen H, Kreiman G, Steen JA.

Nat Commun. 2014 Nov 18;5:5429. doi: 10.1038/ncomms6429.


Characterization of the lipopolysaccharide produced by Pasteurella multocida serovars 6, 7 and 16: identification of lipopolysaccharide genotypes L4 and L8.

Harper M, St Michael F, Steen JA, John M, Wright A, van Dorsten L, Vinogradov E, Adler B, Cox AD, Boyce JD.

Glycobiology. 2015 Mar;25(3):294-302. doi: 10.1093/glycob/cwu110. Epub 2014 Oct 7.


Basal activity of a PARP1-NuA4 complex varies dramatically across cancer cell lines.

Krukenberg KA, Jiang R, Steen JA, Mitchison TJ.

Cell Rep. 2014 Sep 25;8(6):1808-1818. doi: 10.1016/j.celrep.2014.08.009. Epub 2014 Sep 4.


Production of the short peptide surfactant DAMP4 from glucose or sucrose in high cell density cultures of Escherichia coli BL21(DE3).

Bruschi M, Krömer JO, Steen JA, Nielsen LK.

Microb Cell Fact. 2014 Aug 19;13:99. doi: 10.1186/s12934-014-0099-y.


Characterization of an IncN2-type blaNDM-₁-carrying plasmid in Escherichia coli ST131 and Klebsiella pneumoniae ST11 and ST15 isolates in Thailand.

Netikul T, Sidjabat HE, Paterson DL, Kamolvit W, Tantisiriwat W, Steen JA, Kiratisin P.

J Antimicrob Chemother. 2014 Nov;69(11):3161-3. doi: 10.1093/jac/dku275. Epub 2014 Aug 4. No abstract available.


Insight into hyaluronic acid molecular weight control.

Marcellin E, Steen JA, Nielsen LK.

Appl Microbiol Biotechnol. 2014 Aug;98(16):6947-56. doi: 10.1007/s00253-014-5853-x. Epub 2014 Jun 24. Review.


Genome Sequence of Enterotoxigenic Escherichia coli Strain B2C.

Madhavan TP, Steen JA, Hugenholtz P, Sakellaris H.

Genome Announc. 2014 Apr 10;2(2). pii: e00247-14. doi: 10.1128/genomeA.00247-14.


An expanded genomic representation of the phylum cyanobacteria.

Soo RM, Skennerton CT, Sekiguchi Y, Imelfort M, Paech SJ, Dennis PG, Steen JA, Parks DH, Tyson GW, Hugenholtz P.

Genome Biol Evol. 2014 May;6(5):1031-45. doi: 10.1093/gbe/evu073.


The trehalose phosphotransferase system (PTS) in E. coli W can transport low levels of sucrose that are sufficient to facilitate induction of the csc sucrose catabolism operon.

Steen JA, Bohlke N, Vickers CE, Nielsen LK.

PLoS One. 2014 Feb 28;9(2):e88688. doi: 10.1371/journal.pone.0088688. eCollection 2014.


Single clinical isolates from acute uncomplicated urinary tract infections are representative of dominant in situ populations.

Willner D, Low S, Steen JA, George N, Nimmo GR, Schembri MA, Hugenholtz P.

mBio. 2014 Feb 25;5(2):e01064-13. doi: 10.1128/mBio.01064-13.


Co-regulation proteomics reveals substrates and mechanisms of APC/C-dependent degradation.

Singh SA, Winter D, Kirchner M, Chauhan R, Ahmed S, Ozlu N, Tzur A, Steen JA, Steen H.

EMBO J. 2014 Feb 18;33(4):385-99. doi: 10.1002/embj.201385876. Epub 2014 Feb 6.


Entryway into the child protection system: the impacts of child maltreatment reporting policies and reporting system structures.

Steen JA, Duran L.

Child Abuse Negl. 2014 May;38(5):868-74. doi: 10.1016/j.chiabu.2013.11.009. Epub 2013 Dec 31.


In-solution fluorescence in situ hybridization and fluorescence-activated cell sorting for single cell and population genome recovery.

Haroon MF, Skennerton CT, Steen JA, Lachner N, Hugenholtz P, Tyson GW.

Methods Enzymol. 2013;531:3-19. doi: 10.1016/B978-0-12-407863-5.00001-0.


In vivo evolution of antimicrobial resistance in a series of Staphylococcus aureus patient isolates: the entire picture or a cautionary tale?

van Hal SJ, Steen JA, Espedido BA, Grimmond SM, Cooper MA, Holden MT, Bentley SD, Gosbell IB, Jensen SO.

J Antimicrob Chemother. 2014 Feb;69(2):363-7. doi: 10.1093/jac/dkt354. Epub 2013 Sep 18.


Nonparametric Bayesian evaluation of differential protein quantification.

Serang O, Cansizoglu AE, Käll L, Steen H, Steen JA.

J Proteome Res. 2013 Oct 4;12(10):4556-65. doi: 10.1021/pr400678m. Epub 2013 Sep 11.


Pasteurella multocida Heddleston serovar 3 and 4 strains share a common lipopolysaccharide biosynthesis locus but display both inter- and intrastrain lipopolysaccharide heterogeneity.

Harper M, St Michael F, John M, Vinogradov E, Steen JA, van Dorsten L, Steen JA, Turni C, Blackall PJ, Adler B, Cox AD, Boyce JD.

J Bacteriol. 2013 Nov;195(21):4854-64. doi: 10.1128/JB.00779-13. Epub 2013 Aug 23.


The role of hyaluronic acid precursor concentrations in molecular weight control in Streptococcus zooepidemicus.

Chen WY, Marcellin E, Steen JA, Nielsen LK.

Mol Biotechnol. 2014 Feb;56(2):147-56. doi: 10.1007/s12033-013-9690-4.


Diaminothiazoles modify Tau phosphorylation and improve the tauopathy in mouse models.

Zhang X, Hernandez I, Rei D, Mair W, Laha JK, Cornwell ME, Cuny GD, Tsai LH, Steen JA, Kosik KS.

J Biol Chem. 2013 Jul 26;288(30):22042-56. doi: 10.1074/jbc.M112.436402. Epub 2013 Jun 4.


Novel keratin (KeraStat™) and polyurethane (Nanosan(R)-Sorb) biomaterials are hemostatic in a porcine lethal extremity hemorrhage model.

Burnett LR, Richter JG, Rahmany MB, Soler R, Steen JA, Orlando G, Abouswareb T, Van Dyke ME.

J Biomater Appl. 2014 Feb;28(6):869-79. doi: 10.1177/0885328213484975. Epub 2013 Apr 16.


Whole genome sequence analysis of the first Australian OXA-48-producing outbreak-associated Klebsiella pneumoniae isolates: the resistome and in vivo evolution.

Espedido BA, Steen JA, Ziochos H, Grimmond SM, Cooper MA, Gosbell IB, van Hal SJ, Jensen SO.

PLoS One. 2013;8(3):e59920. doi: 10.1371/journal.pone.0059920. Epub 2013 Mar 29.


Gas2l3, a novel constriction site-associated protein whose regulation is mediated by the APC/C Cdh1 complex.

Pe'er T, Lahmi R, Sharaby Y, Chorni E, Noach M, Vecsler M, Zlotorynski E, Steen H, Steen JA, Tzur A.

PLoS One. 2013;8(2):e57532. doi: 10.1371/journal.pone.0057532. Epub 2013 Feb 28.


SweetSEQer, simple de novo filtering and annotation of glycoconjugate mass spectra.

Serang O, Froehlich JW, Muntel J, McDowell G, Steen H, Lee RS, Steen JA.

Mol Cell Proteomics. 2013 Jun;12(6):1735-40. doi: 10.1074/mcp.O112.025940. Epub 2013 Feb 26.


A classifier based on accurate mass measurements to aid large scale, unbiased glycoproteomics.

Froehlich JW, Dodds ED, Wilhelm M, Serang O, Steen JA, Lee RS.

Mol Cell Proteomics. 2013 Apr;12(4):1017-25. doi: 10.1074/mcp.M112.025494. Epub 2013 Feb 25.


Saccharopolyspora erythraea's genome is organised in high-order transcriptional regions mediated by targeted degradation at the metabolic switch.

Marcellin E, Mercer TR, Licona-Cassani C, Palfreyman RW, Dinger ME, Steen JA, Mattick JS, Nielsen LK.

BMC Genomics. 2013 Jan 16;14:15. doi: 10.1186/1471-2164-14-15.


A non-parametric cutout index for robust evaluation of identified proteins.

Serang O, Paulo J, Steen H, Steen JA.

Mol Cell Proteomics. 2013 Mar;12(3):807-12. doi: 10.1074/mcp.O112.022863. Epub 2013 Jan 4.


Structure and biosynthetic locus of the lipopolysaccharide outer core produced by Pasteurella multocida serovars 8 and 13 and the identification of a novel phospho-glycero moiety.

Harper M, St Michael F, Vinogradov E, John M, Steen JA, van Dorsten L, Boyce JD, Adler B, Cox AD.

Glycobiology. 2013 Mar;23(3):286-94. doi: 10.1093/glycob/cws154. Epub 2012 Oct 31.


A practical guide to the FLEXIQuant method.

Singh S, Kirchner M, Steen JA, Steen H.

Methods Mol Biol. 2012;893:295-319. doi: 10.1007/978-1-61779-885-6_19.


FLEXIQinase, a mass spectrometry-based assay, to unveil multikinase mechanisms.

Singh SA, Winter D, Bilimoria PM, Bonni A, Steen H, Steen JA.

Nat Methods. 2012 Apr 8;9(5):504-8. doi: 10.1038/nmeth.1970.


Pleiotropic effects of miR-183~96~182 converge to regulate cell survival, proliferation and migration in medulloblastoma.

Weeraratne SD, Amani V, Teider N, Pierre-Francois J, Winter D, Kye MJ, Sengupta S, Archer T, Remke M, Bai AH, Warren P, Pfister SM, Steen JA, Pomeroy SL, Cho YJ.

Acta Neuropathol. 2012 Apr;123(4):539-52. doi: 10.1007/s00401-012-0969-5. Epub 2012 Mar 10.


Carriage of an ACME II variant may have contributed to methicillin-resistant Staphylococcus aureus sequence type 239-like strain replacement in Liverpool Hospital, Sydney, Australia.

Espedido BA, Steen JA, Barbagiannakos T, Mercer J, Paterson DL, Grimmond SM, Cooper MA, Gosbell IB, van Hal SJ, Jensen SO.

Antimicrob Agents Chemother. 2012 Jun;56(6):3380-3. doi: 10.1128/AAC.00013-12. Epub 2012 Mar 5.


MicroRNAs and their isomiRs function cooperatively to target common biological pathways.

Cloonan N, Wani S, Xu Q, Gu J, Lea K, Heater S, Barbacioru C, Steptoe AL, Martin HC, Nourbakhsh E, Krishnan K, Gardiner B, Wang X, Nones K, Steen JA, Matigian NA, Wood DL, Kassahn KS, Waddell N, Shepherd J, Lee C, Ichikawa J, McKernan K, Bramlett K, Kuersten S, Grimmond SM.

Genome Biol. 2011 Dec 30;12(12):R126. doi: 10.1186/gb-2011-12-12-r126.


Phasevarion mediated epigenetic gene regulation in Helicobacter pylori.

Srikhanta YN, Gorrell RJ, Steen JA, Gawthorne JA, Kwok T, Grimmond SM, Robins-Browne RM, Jennings MP.

PLoS One. 2011;6(12):e27569. doi: 10.1371/journal.pone.0027569. Epub 2011 Dec 5.


mz5: space- and time-efficient storage of mass spectrometry data sets.

Wilhelm M, Kirchner M, Steen JA, Steen H.

Mol Cell Proteomics. 2012 Jan;11(1):O111.011379. doi: 10.1074/mcp.O111.011379. Epub 2011 Sep 29.


NMDA mediated contextual conditioning changes miRNA expression.

Kye MJ, Neveu P, Lee YS, Zhou M, Steen JA, Sahin M, Kosik KS, Silva AJ.

PLoS One. 2011;6(9):e24682. doi: 10.1371/journal.pone.0024682. Epub 2011 Sep 12.

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