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Items: 19


The INNs and outs of antibody nonproprietary names.

Jones TD, Carter PJ, Plückthun A, Vásquez M, Holgate RG, Hötzel I, Popplewell AG, Parren PW, Enzelberger M, Rademaker HJ, Clark MR, Lowe DC, Dahiyat BI, Smith V, Lambert JM, Wu H, Reilly M, Haurum JS, Dübel S, Huston JS, Schirrmann T, Janssen RA, Steegmaier M, Gross JA, Bradbury AR, Burton DR, Dimitrov DS, Chester KA, Glennie MJ, Davies J, Walker A, Martin S, McCafferty J, Baker MP.

MAbs. 2016;8(1):1-9. doi: 10.1080/19420862.2015.1114320.


BI 6727, a Polo-like kinase inhibitor with improved pharmacokinetic profile and broad antitumor activity.

Rudolph D, Steegmaier M, Hoffmann M, Grauert M, Baum A, Quant J, Haslinger C, Garin-Chesa P, Adolf GR.

Clin Cancer Res. 2009 May 1;15(9):3094-102. doi: 10.1158/1078-0432.CCR-08-2445. Epub 2009 Apr 21.


The small-molecule inhibitor BI 2536 reveals novel insights into mitotic roles of polo-like kinase 1.

Lénárt P, Petronczki M, Steegmaier M, Di Fiore B, Lipp JJ, Hoffmann M, Rettig WJ, Kraut N, Peters JM.

Curr Biol. 2007 Feb 20;17(4):304-15. Epub 2007 Feb 8.


BI 2536, a potent and selective inhibitor of polo-like kinase 1, inhibits tumor growth in vivo.

Steegmaier M, Hoffmann M, Baum A, Lénárt P, Petronczki M, Krssák M, Gürtler U, Garin-Chesa P, Lieb S, Quant J, Grauert M, Adolf GR, Kraut N, Peters JM, Rettig WJ.

Curr Biol. 2007 Feb 20;17(4):316-22. Epub 2007 Feb 8.


BI-D1870 is a specific inhibitor of the p90 RSK (ribosomal S6 kinase) isoforms in vitro and in vivo.

Sapkota GP, Cummings L, Newell FS, Armstrong C, Bain J, Frodin M, Grauert M, Hoffmann M, Schnapp G, Steegmaier M, Cohen P, Alessi DR.

Biochem J. 2007 Jan 1;401(1):29-38.


SNARE protein trafficking in polarized MDCK cells.

Steegmaier M, Lee KC, Prekeris R, Scheller RH.

Traffic. 2000 Jul;1(7):553-60.


Syntaxin 17 is abundant in steroidogenic cells and implicated in smooth endoplasmic reticulum membrane dynamics.

Steegmaier M, Oorschot V, Klumperman J, Scheller RH.

Mol Biol Cell. 2000 Aug;11(8):2719-31.


nSec1 binds a closed conformation of syntaxin1A.

Yang B, Steegmaier M, Gonzalez LC Jr, Scheller RH.

J Cell Biol. 2000 Jan 24;148(2):247-52.


Vesicle-associated membrane protein 4 is implicated in trans-Golgi network vesicle trafficking.

Steegmaier M, Klumperman J, Foletti DL, Yoo JS, Scheller RH.

Mol Biol Cell. 1999 Jun;10(6):1957-72.


SNARE interactions are not selective. Implications for membrane fusion specificity.

Yang B, Gonzalez L Jr, Prekeris R, Steegmaier M, Advani RJ, Scheller RH.

J Biol Chem. 1999 Feb 26;274(9):5649-53.


Three novel proteins of the syntaxin/SNAP-25 family.

Steegmaier M, Yang B, Yoo JS, Huang B, Shen M, Yu S, Luo Y, Scheller RH.

J Biol Chem. 1998 Dec 18;273(51):34171-9.


Localization, dynamics, and protein interactions reveal distinct roles for ER and Golgi SNAREs.

Hay JC, Klumperman J, Oorschot V, Steegmaier M, Kuo CS, Scheller RH.

J Cell Biol. 1998 Jun 29;141(7):1489-502. Erratum in: J Cell Biol 1998 Aug 10;142(3):following 881.


The binding of T cell-expressed P-selectin glycoprotein ligand-1 to E- and P-selectin is differentially regulated.

Borges E, Pendl G, Eytner R, Steegmaier M, Zöllner O, Vestweber D.

J Biol Chem. 1997 Nov 7;272(45):28786-92.


The P-selectin glycoprotein ligand-1 is important for recruitment of neutrophils into inflamed mouse peritoneum.

Borges E, Eytner R, Moll T, Steegmaier M, Campbell MA, Ley K, Mossmann H, Vestweber D.

Blood. 1997 Sep 1;90(5):1934-42.


The E-selectin-ligand ESL-1 is located in the Golgi as well as on microvilli on the cell surface.

Steegmaier M, Borges E, Berger J, Schwarz H, Vestweber D.

J Cell Sci. 1997 Mar;110 ( Pt 6):687-94.


L-selectin from human, but not from mouse neutrophils binds directly to E-selectin.

Zöllner O, Lenter MC, Blanks JE, Borges E, Steegmaier M, Zerwes HG, Vestweber D.

J Cell Biol. 1997 Feb 10;136(3):707-16.


P-selectin glycoprotein ligand-1 (PSGL-1) on T helper 1 but not on T helper 2 cells binds to P-selectin and supports migration into inflamed skin.

Borges E, Tietz W, Steegmaier M, Moll T, Hallmann R, Hamann A, Vestweber D.

J Exp Med. 1997 Feb 3;185(3):573-8.


The E-selectin-ligand ESL-1 is a variant of a receptor for fibroblast growth factor.

Steegmaier M, Levinovitz A, Isenmann S, Borges E, Lenter M, Kocher HP, Kleuser B, Vestweber D.

Nature. 1995 Feb 16;373(6515):615-20.


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