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Items: 1 to 50 of 95

1.

MIDD0301 - A first-in-class anti-inflammatory asthma drug targets GABAA receptors without causing systemic immune suppression.

Zahn NM, Huber AT, Mikulsky BN, Stepanski ME, Kehoe AS, Li G, Schussman M, Rashid Roni MS, Kodali R, Cook JM, Stafford DC, Steeber DA, Arnold LA.

Basic Clin Pharmacol Toxicol. 2019 Jul;125(1):75-84. doi: 10.1111/bcpt.13206. Epub 2019 Feb 21.

PMID:
30694594
2.

A Novel Orally Available Asthma Drug Candidate That Reduces Smooth Muscle Constriction and Inflammation by Targeting GABAA Receptors in the Lung.

Forkuo GS, Nieman AN, Kodali R, Zahn NM, Li G, Rashid Roni MS, Stephen MR, Harris TW, Jahan R, Guthrie ML, Yu OB, Fisher JL, Yocum GT, Emala CW, Steeber DA, Stafford DC, Cook JM, Arnold LA.

Mol Pharm. 2018 May 7;15(5):1766-1777. doi: 10.1021/acs.molpharmaceut.7b01013. Epub 2018 Apr 2.

3.

Alleviation of Multiple Asthmatic Pathologic Features with Orally Available and Subtype Selective GABAA Receptor Modulators.

Forkuo GS, Nieman AN, Yuan NY, Kodali R, Yu OB, Zahn NM, Jahan R, Li G, Stephen MR, Guthrie ML, Poe MM, Hartzler BD, Harris TW, Yocum GT, Emala CW, Steeber DA, Stafford DC, Cook JM, Arnold LA.

Mol Pharm. 2017 Jun 5;14(6):2088-2098. doi: 10.1021/acs.molpharmaceut.7b00183. Epub 2017 May 1.

4.

Tumor-induced MDSC act via remote control to inhibit L-selectin-dependent adaptive immunity in lymph nodes.

Ku AW, Muhitch JB, Powers CA, Diehl M, Kim M, Fisher DT, Sharda AP, Clements VK, O'Loughlin K, Minderman H, Messmer MN, Ma J, Skitzki JJ, Steeber DA, Walcheck B, Ostrand-Rosenberg S, Abrams SI, Evans SS.

Elife. 2016 Dec 8;5. pii: e17375. doi: 10.7554/eLife.17375.

5.

Nickel oxide hollow microsphere for non-enzyme glucose detection.

Ci S, Huang T, Wen Z, Cui S, Mao S, Steeber DA, Chen J.

Biosens Bioelectron. 2014 Apr 15;54:251-7. doi: 10.1016/j.bios.2013.11.006. Epub 2013 Nov 12.

PMID:
24287412
6.
7.

Direct growth of vertically-oriented graphene for field-effect transistor biosensor.

Mao S, Yu K, Chang J, Steeber DA, Ocola LE, Chen J.

Sci Rep. 2013;3:1696. doi: 10.1038/srep01696.

8.

Single-walled carbon nanotube field-effect transistors with graphene oxide passivation for fast, sensitive, and selective protein detection.

Chang J, Mao S, Zhang Y, Cui S, Steeber DA, Chen J.

Biosens Bioelectron. 2013 Apr 15;42:186-92. doi: 10.1016/j.bios.2012.10.041. Epub 2012 Oct 23.

PMID:
23202350
9.

Gold Nanorods Conjugated with Doxorubicin and cRGD for Combined Anticancer Drug Delivery and PET Imaging.

Xiao Y, Hong H, Matson VZ, Javadi A, Xu W, Yang Y, Zhang Y, Engle JW, Nickles RJ, Cai W, Steeber DA, Gong S.

Theranostics. 2012;2(8):757-68. doi: 10.7150/thno.4756. Epub 2012 Aug 6.

10.

Signaling through L-selectin mediates enhanced chemotaxis of lymphocyte subsets to secondary lymphoid tissue chemokine.

Subramanian H, Grailer JJ, Ohlrich KC, Rymaszewski AL, Loppnow JJ, Kodera M, Conway RM, Steeber DA.

J Immunol. 2012 Apr 1;188(7):3223-36. doi: 10.4049/jimmunol.1101032. Epub 2012 Mar 2.

11.

Cell individuality: the bistable gene expression of the type III secretion system in Dickeya dadantii 3937.

Zeng Q, Laiosa MD, Steeber DA, Biddle EM, Peng Q, Yang CH.

Mol Plant Microbe Interact. 2012 Jan;25(1):37-47. doi: 10.1094/MPMI-05-11-0105.

12.

cRGD-functionalized, DOX-conjugated, and ⁶⁴Cu-labeled superparamagnetic iron oxide nanoparticles for targeted anticancer drug delivery and PET/MR imaging.

Yang X, Hong H, Grailer JJ, Rowland IJ, Javadi A, Hurley SA, Xiao Y, Yang Y, Zhang Y, Nickles RJ, Cai W, Steeber DA, Gong S.

Biomaterials. 2011 Jun;32(17):4151-60. doi: 10.1016/j.biomaterials.2011.02.006. Epub 2011 Mar 2.

13.

α4β7 Integrin is essential for contact hypersensitivity by regulating migration of T cells to skin.

Ohmatsu H, Kadono T, Sugaya M, Tomita M, Kai H, Miyagaki T, Saeki H, Tamaki K, Steeber DA, Tedder TF, Sato S.

J Allergy Clin Immunol. 2010 Dec;126(6):1267-76. doi: 10.1016/j.jaci.2010.08.048. Epub 2010 Nov 3.

PMID:
21047673
14.

Multifunctional stable and pH-responsive polymer vesicles formed by heterofunctional triblock copolymer for targeted anticancer drug delivery and ultrasensitive MR imaging.

Yang X, Grailer JJ, Rowland IJ, Javadi A, Hurley SA, Matson VZ, Steeber DA, Gong S.

ACS Nano. 2010 Nov 23;4(11):6805-17. doi: 10.1021/nn101670k. Epub 2010 Oct 19.

PMID:
20958084
15.

Multifunctional SPIO/DOX-loaded wormlike polymer vesicles for cancer therapy and MR imaging.

Yang X, Grailer JJ, Rowland IJ, Javadi A, Hurley SA, Steeber DA, Gong S.

Biomaterials. 2010 Dec;31(34):9065-73. doi: 10.1016/j.biomaterials.2010.08.039. Epub 2010 Sep 9.

PMID:
20828811
16.

Multifunctional polymeric vesicles for targeted drug delivery and imaging.

Yang X, Grailer JJ, Pilla S, Steeber DA, Gong S, Shuai X.

Biofabrication. 2010 Jun;2(2):025004. doi: 10.1088/1758-5082/2/2/025004. Epub 2010 Jun 9.

PMID:
20811132
17.

Tumor-targeting, pH-responsive, and stable unimolecular micelles as drug nanocarriers for targeted cancer therapy.

Yang X, Grailer JJ, Pilla S, Steeber DA, Gong S.

Bioconjug Chem. 2010 Mar 17;21(3):496-504. doi: 10.1021/bc900422j. Epub 2010 Feb 17.

PMID:
20163170
18.

L-selectin: role in regulating homeostasis and cutaneous inflammation.

Grailer JJ, Kodera M, Steeber DA.

J Dermatol Sci. 2009 Dec;56(3):141-7. doi: 10.1016/j.jdermsci.2009.10.001. Epub 2009 Nov 3. Review.

19.

Gold nanoparticles with a monolayer of doxorubicin-conjugated amphiphilic block copolymer for tumor-targeted drug delivery.

Prabaharan M, Grailer JJ, Pilla S, Steeber DA, Gong S.

Biomaterials. 2009 Oct;30(30):6065-75. doi: 10.1016/j.biomaterials.2009.07.048. Epub 2009 Aug 12.

PMID:
19674777
20.

Amphiphilic multi-arm-block copolymer conjugated with doxorubicin via pH-sensitive hydrazone bond for tumor-targeted drug delivery.

Prabaharan M, Grailer JJ, Pilla S, Steeber DA, Gong S.

Biomaterials. 2009 Oct;30(29):5757-66. doi: 10.1016/j.biomaterials.2009.07.020. Epub 2009 Jul 29.

PMID:
19643472
21.

Biodegradable hydrogels based on novel photopolymerizable guar gum-methacrylate macromonomers for in situ fabrication of tissue engineering scaffolds.

Tiwari A, Grailer JJ, Pilla S, Steeber DA, Gong S.

Acta Biomater. 2009 Nov;5(9):3441-52. doi: 10.1016/j.actbio.2009.06.001. Epub 2009 Jun 6.

PMID:
19505599
22.

Thermosensitive micelles based on folate-conjugated poly(N-vinylcaprolactam)-block-poly(ethylene glycol) for tumor-targeted drug delivery.

Prabaharan M, Grailer JJ, Steeber DA, Gong S.

Macromol Biosci. 2009 Aug 11;9(8):744-53. doi: 10.1002/mabi.200800366.

PMID:
19370751
23.

Folate-conjugated amphiphilic hyperbranched block copolymers based on Boltorn H40, poly(L-lactide) and poly(ethylene glycol) for tumor-targeted drug delivery.

Prabaharan M, Grailer JJ, Pilla S, Steeber DA, Gong S.

Biomaterials. 2009 Jun;30(16):3009-19. doi: 10.1016/j.biomaterials.2009.02.011. Epub 2009 Feb 27.

PMID:
19250665
24.

Fabrication and characterization of microwave immunosensors based on organic semiconductors with nanogold-labeled antibody.

Li F, Klemer DP, Kimani JK, Mao S, Chen J, Steeber DA.

Conf Proc IEEE Eng Med Biol Soc. 2008;2008:2381-4. doi: 10.1109/IEMBS.2008.4649678.

PMID:
19163181
25.

Amphiphilic multi-arm block copolymer based on hyperbranched polyester, poly(L-lactide) and poly(ethylene glycol) as a drug delivery carrier.

Prabaharan M, Grailer JJ, Pilla S, Steeber DA, Gong S.

Macromol Biosci. 2009 May 13;9(5):515-24. doi: 10.1002/mabi.200800269.

PMID:
19089867
26.

Stimuli-responsive chitosan-graft-poly(N-vinylcaprolactam) as a promising material for controlled hydrophobic drug delivery.

Prabaharan M, Grailer JJ, Steeber DA, Gong S.

Macromol Biosci. 2008 Sep 9;8(9):843-51. doi: 10.1002/mabi.200800010.

PMID:
18504806
27.

T lymphocyte migration to lymph nodes is maintained during homeostatic proliferation.

Kodera M, Grailer JJ, Karalewitz AP, Subramanian H, Steeber DA.

Microsc Microanal. 2008 Jun;14(3):211-24. doi: 10.1017/S1431927608080215. Epub 2008 Mar 3.

PMID:
18312727
28.

The loss of MCP-1 attenuates cutaneous ischemia-reperfusion injury in a mouse model of pressure ulcer.

Saito Y, Hasegawa M, Fujimoto M, Matsushita T, Horikawa M, Takenaka M, Ogawa F, Sugama J, Steeber DA, Sato S, Takehara K.

J Invest Dermatol. 2008 Jul;128(7):1838-51. doi: 10.1038/sj.jid.5701258. Epub 2008 Jan 24.

29.

Polymer semiconductors as a biosensing platform: peroxidase activity of enzyme bound to organic semiconducting films.

Omari EA, Klemer DP, Steeber DA, Gaertner WF.

Conf Proc IEEE Eng Med Biol Soc. 2007;2007:107-10.

PMID:
18001900
30.

B cell depletion delays collagen-induced arthritis in mice: arthritis induction requires synergy between humoral and cell-mediated immunity.

Yanaba K, Hamaguchi Y, Venturi GM, Steeber DA, St Clair EW, Tedder TF.

J Immunol. 2007 Jul 15;179(2):1369-80.

31.

Endothelial selectins regulate skin wound healing in cooperation with L-selectin and ICAM-1.

Yukami T, Hasegawa M, Matsushita Y, Fujita T, Matsushita T, Horikawa M, Komura K, Yanaba K, Hamaguchi Y, Nagaoka T, Ogawa F, Fujimoto M, Steeber DA, Tedder TF, Takehara K, Sato S.

J Leukoc Biol. 2007 Sep;82(3):519-31. Epub 2007 Jun 26.

PMID:
17595378
32.

Intercellular adhesion molecule-1 deficiency attenuates the development of skin fibrosis in tight-skin mice.

Matsushita Y, Hasegawa M, Matsushita T, Fujimoto M, Horikawa M, Fujita T, Kawasuji A, Ogawa F, Steeber DA, Tedder TF, Takehara K, Sato S.

J Immunol. 2007 Jul 1;179(1):698-707.

33.
34.

E- and P-selectins synergistically inhibit bleomycin-induced pulmonary fibrosis.

Horikawa M, Fujimoto M, Hasegawa M, Matsushita T, Hamaguchi Y, Kawasuji A, Matsushita Y, Fujita T, Ogawa F, Takehara K, Steeber DA, Sato S.

Am J Pathol. 2006 Sep;169(3):740-9.

35.

Population behavior analysis of dspE and pelD regulation in Erwinia chrysanthemi 3937.

Peng Q, Yang S, Charkowski AO, Yap MN, Steeber DA, Keen NT, Yang CH.

Mol Plant Microbe Interact. 2006 Apr;19(4):451-7.

36.

L-selectin and intercellular adhesion molecule-1 regulate the development of Concanavalin A-induced liver injury.

Kawasuji A, Hasegawa M, Horikawa M, Fujita T, Matsushita Y, Matsushita T, Fujimoto M, Steeber DA, Tedder TF, Takehara K, Sato S.

J Leukoc Biol. 2006 Apr;79(4):696-705. Epub 2006 Feb 3.

PMID:
16461740
37.

Neonate-primed CD8+ memory cells rival adult-primed memory cells in antigen-driven expansion and anti-viral protection.

Fadel SA, Cowell LG, Cao S, Ozaki DA, Kepler TB, Steeber DA, Sarzotti M.

Int Immunol. 2006 Feb;18(2):249-57. Epub 2006 Jan 17.

PMID:
16418189
38.

Regulation of local and metastatic host-mediated anti-tumour mechanisms by L-selectin and intercellular adhesion molecule-1.

Yamada M, Yanaba K, Hasegawa M, Matsushita Y, Horikawa M, Komura K, Matsushita T, Kawasuji A, Fujita T, Takehara K, Steeber DA, Tedder TF, Sato S.

Clin Exp Immunol. 2006 Feb;143(2):216-27.

40.

A new twist to the leukocyte adhesion cascade: intimate cooperation is key.

Steeber DA, Venturi GM, Tedder TF.

Trends Immunol. 2005 Jan;26(1):9-12. Review.

PMID:
15629403
41.

Mouse CD20 expression and function.

Uchida J, Lee Y, Hasegawa M, Liang Y, Bradney A, Oliver JA, Bowen K, Steeber DA, Haas KM, Poe JC, Tedder TF.

Int Immunol. 2004 Jan;16(1):119-29.

PMID:
14688067
42.

Leukocyte migration is regulated by L-selectin endoproteolytic release.

Venturi GM, Tu L, Kadono T, Khan AI, Fujimoto Y, Oshel P, Bock CB, Miller AS, Albrecht RM, Kubes P, Steeber DA, Tedder TF.

Immunity. 2003 Nov;19(5):713-24.

43.

Ultraviolet light exposure suppresses contact hypersensitivity by abrogating endothelial intercellular adhesion molecule-1 up-regulation at the elicitation site.

Komura K, Hasegawa M, Hamaguchi Y, Saito E, Kaburagi Y, Yanaba K, Kawara S, Takehara K, Seki M, Steeber DA, Tedder TF, Sato S.

J Immunol. 2003 Sep 15;171(6):2855-62.

44.

Relative contributions of selectins and intercellular adhesion molecule-1 to tissue injury induced by immune complex deposition.

Yanaba K, Kaburagi Y, Takehara K, Steeber DA, Tedder TF, Sato S.

Am J Pathol. 2003 May;162(5):1463-73.

45.

L-selectin or ICAM-1 deficiency reduces an immediate-type hypersensitivity response by preventing mast cell recruitment in repeated elicitation of contact hypersensitivity.

Shimada Y, Hasegawa M, Kaburagi Y, Hamaguchi Y, Komura K, Saito E, Takehara K, Steeber DA, Tedder TF, Sato S.

J Immunol. 2003 Apr 15;170(8):4325-34.

46.

Complement receptors CD21/35 link innate and protective immunity during Streptococcus pneumoniae infection by regulating IgG3 antibody responses.

Haas KM, Hasegawa M, Steeber DA, Poe JC, Zabel MD, Bock CB, Karp DR, Briles DE, Weis JH, Tedder TF.

Immunity. 2002 Dec;17(6):713-23.

47.

Intercellular adhesion molecule-1 and L-selectin regulate bleomycin-induced lung fibrosis.

Hamaguchi Y, Nishizawa Y, Yasui M, Hasegawa M, Kaburagi Y, Komura K, Nagaoka T, Saito E, Shimada Y, Takehara K, Kadono T, Steeber DA, Tedder TF, Sato S.

Am J Pathol. 2002 Nov;161(5):1607-18.

48.
49.

A functional role for circulating mouse L-selectin in regulating leukocyte/endothelial cell interactions in vivo.

Tu L, Poe JC, Kadono T, Venturi GM, Bullard DC, Tedder TF, Steeber DA.

J Immunol. 2002 Aug 15;169(4):2034-43.

50.

CD83 expression influences CD4+ T cell development in the thymus.

Fujimoto Y, Tu L, Miller AS, Bock C, Fujimoto M, Doyle C, Steeber DA, Tedder TF.

Cell. 2002 Mar 22;108(6):755-67.

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