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Items: 1 to 50 of 116

1.

Genomic and expression analyses define MUC17 and PCNX1 as predictors of chemotherapy response in breast cancer.

Al Amri WS, Allinson LM, Baxter DE, Bell SM, Hanby AM, Jones SJ, Shaaban AM, Stead LF, Verghese ET, Hughes TA.

Mol Cancer Ther. 2019 Dec 26. pii: molcanther.0940.2019. doi: 10.1158/1535-7163.MCT-19-0940. [Epub ahead of print]

PMID:
31879365
2.

Expression profiling of single cells and patient cohorts identifies multiple immunosuppressive pathways and an altered NK cell phenotype in glioblastoma.

Close HJ, Stead LF, Nsengimana J, Reilly KA, Droop A, Wurdak H, Mathew RK, Corns R, Newton-Bishop J, Melcher AA, Short SC, Cook GP, Wilson EB.

Clin Exp Immunol. 2019 Nov 30. doi: 10.1111/cei.13403. [Epub ahead of print]

PMID:
31784984
3.

Longitudinal molecular trajectories of diffuse glioma in adults.

Barthel FP, Johnson KC, Varn FS, Moskalik AD, Tanner G, Kocakavuk E, Anderson KJ, Abiola O, Aldape K, Alfaro KD, Alpar D, Amin SB, Ashley DM, Bandopadhayay P, Barnholtz-Sloan JS, Beroukhim R, Bock C, Brastianos PK, Brat DJ, Brodbelt AR, Bruns AF, Bulsara KR, Chakrabarty A, Chakravarti A, Chuang JH, Claus EB, Cochran EJ, Connelly J, Costello JF, Finocchiaro G, Fletcher MN, French PJ, Gan HK, Gilbert MR, Gould PV, Grimmer MR, Iavarone A, Ismail A, Jenkinson MD, Khasraw M, Kim H, Kouwenhoven MCM, LaViolette PS, Li M, Lichter P, Ligon KL, Lowman AK, Malta TM, Mazor T, McDonald KL, Molinaro AM, Nam DH, Nayyar N, Ng HK, Ngan CY, Niclou SP, Niers JM, Noushmehr H, Noorbakhsh J, Ormond DR, Park CK, Poisson LM, Rabadan R, Radlwimmer B, Rao G, Reifenberger G, Sa JK, Schuster M, Shaw BL, Short SC, Smitt PAS, Sloan AE, Smits M, Suzuki H, Tabatabai G, Van Meir EG, Watts C, Weller M, Wesseling P, Westerman BA, Widhalm G, Woehrer A, Yung WKA, Zadeh G, Huse JT, De Groot JF, Stead LF, Verhaak RGW; GLASS Consortium.

Nature. 2019 Dec;576(7785):112-120. doi: 10.1038/s41586-019-1775-1. Epub 2019 Nov 20.

PMID:
31748746
4.

Chemically induced neurite-like outgrowth reveals a multicellular network function in patient-derived glioblastoma cells.

da Silva B, Irving BK, Polson ES, Droop A, Griffiths HBS, Mathew RK, Stead LF, Marrison J, Williams C, Williams J, Short SC, Scarcia M, O'Toole PJ, Allison SJ, Mavria G, Wurdak H.

J Cell Sci. 2019 Oct 10;132(19). pii: jcs228452. doi: 10.1242/jcs.228452.

PMID:
31515278
5.

Doomed from the TERT? A Two-Stage Model of Tumorigenesis in IDH-Wild-Type Glioblastoma.

Stead LF, Verhaak RGW.

Cancer Cell. 2019 Apr 15;35(4):542-544. doi: 10.1016/j.ccell.2019.03.009.

PMID:
30991024
6.

Simulation of heterogeneous tumour genomes with HeteroGenesis and in silico whole exome sequencing.

Tanner G, Westhead DR, Droop A, Stead LF.

Bioinformatics. 2019 Aug 15;35(16):2850-2852. doi: 10.1093/bioinformatics/bty1063.

7.

Intravenous delivery of oncolytic reovirus to brain tumor patients immunologically primes for subsequent checkpoint blockade.

Samson A, Scott KJ, Taggart D, West EJ, Wilson E, Nuovo GJ, Thomson S, Corns R, Mathew RK, Fuller MJ, Kottke TJ, Thompson JM, Ilett EJ, Cockle JV, van Hille P, Sivakumar G, Polson ES, Turnbull SJ, Appleton ES, Migneco G, Rose AS, Coffey MC, Beirne DA, Collinson FJ, Ralph C, Alan Anthoney D, Twelves CJ, Furness AJ, Quezada SA, Wurdak H, Errington-Mais F, Pandha H, Harrington KJ, Selby PJ, Vile RG, Griffin SD, Stead LF, Short SC, Melcher AA.

Sci Transl Med. 2018 Jan 3;10(422). pii: eaam7577. doi: 10.1126/scitranslmed.aam7577.

8.

How to analyse the spatiotemporal tumour samples needed to investigate cancer evolution: A case study using paired primary and recurrent glioblastoma.

Droop A, Bruns A, Tanner G, Rippaus N, Morton R, Harrison S, King H, Ashton K, Syed K, Jenkinson MD, Brodbelt A, Chakrabarty A, Ismail A, Short S, Stead LF.

Int J Cancer. 2018 Apr 15;142(8):1620-1626. doi: 10.1002/ijc.31184. Epub 2017 Dec 14.

9.

Genomic Subtypes of Non-invasive Bladder Cancer with Distinct Metabolic Profile and Female Gender Bias in KDM6A Mutation Frequency.

Hurst CD, Alder O, Platt FM, Droop A, Stead LF, Burns JE, Burghel GJ, Jain S, Klimczak LJ, Lindsay H, Roulson JA, Taylor CF, Thygesen H, Cameron AJ, Ridley AJ, Mott HR, Gordenin DA, Knowles MA.

Cancer Cell. 2017 Nov 13;32(5):701-715.e7. doi: 10.1016/j.ccell.2017.08.005.

10.

Group behaviour therapy programmes for smoking cessation.

Stead LF, Carroll AJ, Lancaster T.

Cochrane Database Syst Rev. 2017 Mar 31;3:CD001007. doi: 10.1002/14651858.CD001007.pub3. Review.

11.

Individual behavioural counselling for smoking cessation.

Lancaster T, Stead LF.

Cochrane Database Syst Rev. 2017 Mar 31;3:CD001292. doi: 10.1002/14651858.CD001292.pub3. Review.

12.

Upregulated WEE1 protects endothelial cells of colorectal cancer liver metastases.

Webster PJ, Littlejohns AT, Gaunt HJ, Young RS, Rode B, Ritchie JE, Stead LF, Harrison S, Droop A, Martin HL, Tomlinson DC, Hyman AJ, Appleby HL, Boxall S, Bruns AF, Li J, Prasad RK, Lodge JPA, Burke DA, Beech DJ.

Oncotarget. 2017 Jun 27;8(26):42288-42299. doi: 10.18632/oncotarget.15039.

13.

RAD51 Is a Selective DNA Repair Target to Radiosensitize Glioma Stem Cells.

King HO, Brend T, Payne HL, Wright A, Ward TA, Patel K, Egnuni T, Stead LF, Patel A, Wurdak H, Short SC.

Stem Cell Reports. 2017 Jan 10;8(1):125-139. doi: 10.1016/j.stemcr.2016.12.005.

14.

A Case-Matched Gender Comparison Transcriptomic Screen Identifies eIF4E and eIF5 as Potential Prognostic Markers in Male Breast Cancer.

Humphries MP, Sundara Rajan S, Droop A, Suleman CAB, Carbone C, Nilsson C, Honarpisheh H, Cserni G, Dent J, Fulford L, Jordan LB, Jones JL, Kanthan R, Litwiniuk M, Di Benedetto A, Mottolese M, Provenzano E, Shousha S, Stephens M, Walker RA, Kulka J, Ellis IO, Jeffery M, Thygesen HH, Cappelletti V, Daidone MG, Hedenfalk IA, Fjällskog ML, Melisi D, Stead LF, Shaaban AM, Speirs V.

Clin Cancer Res. 2017 May 15;23(10):2575-2583. doi: 10.1158/1078-0432.CCR-16-1952. Epub 2016 Dec 16.

15.

Is nicotine replacement really ineffective? A reply to Stanley and Massey.

Hughes JR, Fanshawe TR, Stead LF.

J Clin Epidemiol. 2017 Jan;81:143-144. doi: 10.1016/j.jclinepi.2016.08.013. Epub 2016 Sep 20. No abstract available.

PMID:
27663610
16.

Electronic cigarettes for smoking cessation.

Hartmann-Boyce J, McRobbie H, Bullen C, Begh R, Stead LF, Hajek P.

Cochrane Database Syst Rev. 2016 Sep 14;9:CD010216. doi: 10.1002/14651858.CD010216.pub3. Review.

17.

Combined pharmacotherapy and behavioural interventions for smoking cessation.

Stead LF, Koilpillai P, Fanshawe TR, Lancaster T.

Cochrane Database Syst Rev. 2016 Mar 24;3:CD008286. doi: 10.1002/14651858.CD008286.pub3. Review.

PMID:
27009521
18.

Exploring the surfaceome of Ewing sarcoma identifies a new and unique therapeutic target.

Town J, Pais H, Harrison S, Stead LF, Bataille C, Bunjobpol W, Zhang J, Rabbitts TH.

Proc Natl Acad Sci U S A. 2016 Mar 29;113(13):3603-8. doi: 10.1073/pnas.1521251113. Epub 2016 Mar 15.

19.

Elucidating drivers of oral epithelial dysplasia formation and malignant transformation to cancer using RNAseq.

Conway C, Graham JL, Chengot P, Daly C, Chalkley R, Ross L, Droop A, Rabbitts P, Stead LF.

Oncotarget. 2015 Nov 24;6(37):40186-201. doi: 10.18632/oncotarget.5529.

20.

Interventions for smokeless tobacco use cessation.

Ebbert JO, Elrashidi MY, Stead LF.

Cochrane Database Syst Rev. 2015 Oct 26;(10):CD004306. doi: 10.1002/14651858.CD004306.pub5. Review.

21.

Additional behavioural support as an adjunct to pharmacotherapy for smoking cessation.

Stead LF, Koilpillai P, Lancaster T.

Cochrane Database Syst Rev. 2015 Oct 12;(10):CD009670. doi: 10.1002/14651858.CD009670.pub3. Review. Update in: Cochrane Database Syst Rev. 2019 Jun 05;6:CD009670.

PMID:
26457723
22.

Down-Regulation of miR-92 in Breast Epithelial Cells and in Normal but Not Tumour Fibroblasts Contributes to Breast Carcinogenesis.

Smith L, Baxter EW, Chambers PA, Green CA, Hanby AM, Hughes TA, Nash CE, Millican-Slater RA, Stead LF, Verghese ET, Speirs V.

PLoS One. 2015 Oct 5;10(10):e0139698. doi: 10.1371/journal.pone.0139698. eCollection 2015.

23.

Efficacy of interventions to combat tobacco addiction: Cochrane update of 2013 reviews.

Hartmann-Boyce J, Stead LF, Cahill K, Lancaster T.

Addiction. 2014 Sep;109(9):1414-25. doi: 10.1111/add.12633. Epub 2014 Jul 4. Review.

PMID:
24995905
24.

Print-based self-help interventions for smoking cessation.

Hartmann-Boyce J, Lancaster T, Stead LF.

Cochrane Database Syst Rev. 2014 Jun 3;(6):CD001118. doi: 10.1002/14651858.CD001118.pub3. Review. Update in: Cochrane Database Syst Rev. 2019 Jan 09;1:CD001118.

PMID:
24888233
25.

Using common variants to indicate cancer genes.

Stead LF, Thygesen H, Westhead DR, Rabbitts P.

Int J Cancer. 2015 Jan 1;136(1):241-5. doi: 10.1002/ijc.28951. Epub 2014 May 14.

26.

Systematic review and meta-analysis of opioid antagonists for smoking cessation.

David SP, Chu IM, Lancaster T, Stead LF, Evins AE, Prochaska JJ.

BMJ Open. 2014 Mar 14;4(3):e004393. doi: 10.1136/bmjopen-2013-004393. Review.

27.

Acupuncture and related interventions for smoking cessation.

White AR, Rampes H, Liu JP, Stead LF, Campbell J.

Cochrane Database Syst Rev. 2014 Jan 23;(1):CD000009. doi: 10.1002/14651858.CD000009.pub4. Review.

PMID:
24459016
28.

Antidepressants for smoking cessation.

Hughes JR, Stead LF, Hartmann-Boyce J, Cahill K, Lancaster T.

Cochrane Database Syst Rev. 2014 Jan 8;(1):CD000031. doi: 10.1002/14651858.CD000031.pub4. Review.

PMID:
24402784
29.

An integrated inspection of the somatic mutations in a lung squamous cell carcinoma using next-generation sequencing.

Stead LF, Egan P, Devery A, Conway C, Daly C, Berri S, Wood H, Belvedere O, Papagiannopoulos K, Ryan A, Rabbitts P.

PLoS One. 2013 Nov 11;8(11):e78823. doi: 10.1371/journal.pone.0078823. eCollection 2013.

30.

Relapse prevention interventions for smoking cessation.

Hajek P, Stead LF, West R, Jarvis M, Hartmann-Boyce J, Lancaster T.

Cochrane Database Syst Rev. 2013 Aug 20;(8):CD003999. doi: 10.1002/14651858.CD003999.pub4. Review. Update in: Cochrane Database Syst Rev. 2019 Feb 13;2:CD003999.

PMID:
23963584
31.

Nursing interventions for smoking cessation.

Rice VH, Hartmann-Boyce J, Stead LF.

Cochrane Database Syst Rev. 2013 Aug 12;(8):CD001188. doi: 10.1002/14651858.CD001188.pub4. Review. Update in: Cochrane Database Syst Rev. 2017 Dec 15;12 :CD001188.

PMID:
23939719
32.

Telephone counselling for smoking cessation.

Stead LF, Hartmann-Boyce J, Perera R, Lancaster T.

Cochrane Database Syst Rev. 2013 Aug 12;(8):CD002850. doi: 10.1002/14651858.CD002850.pub3. Review. Update in: Cochrane Database Syst Rev. 2019 May 02;5:CD002850.

PMID:
23934971
33.

Internet-based interventions for smoking cessation.

Civljak M, Stead LF, Hartmann-Boyce J, Sheikh A, Car J.

Cochrane Database Syst Rev. 2013 Jul 10;(7):CD007078. doi: 10.1002/14651858.CD007078.pub4. Review. Update in: Cochrane Database Syst Rev. 2017 Sep 04;9:CD007078.

PMID:
23839868
34.

Efficacy of interventions to combat tobacco addiction: Cochrane update of 2012 reviews.

Hartmann-Boyce J, Stead LF, Cahill K, Lancaster T.

Addiction. 2013 Oct;108(10):1711-21. doi: 10.1111/add.12291. Epub 2013 Aug 14.

PMID:
23834141
35.

Accurately identifying low-allelic fraction variants in single samples with next-generation sequencing: applications in tumor subclone resolution.

Stead LF, Sutton KM, Taylor GR, Quirke P, Rabbitts P.

Hum Mutat. 2013 Oct;34(10):1432-8. doi: 10.1002/humu.22365. Epub 2013 Jul 11.

PMID:
23766071
36.

Opioid antagonists for smoking cessation.

David SP, Lancaster T, Stead LF, Evins AE, Prochaska JJ.

Cochrane Database Syst Rev. 2013 Jun 6;(6):CD003086. doi: 10.1002/14651858.CD003086.pub3. Review.

37.

Physician advice for smoking cessation.

Stead LF, Buitrago D, Preciado N, Sanchez G, Hartmann-Boyce J, Lancaster T.

Cochrane Database Syst Rev. 2013 May 31;(5):CD000165. doi: 10.1002/14651858.CD000165.pub4. Review.

PMID:
23728631
38.

Behavioural interventions as adjuncts to pharmacotherapy for smoking cessation.

Stead LF, Lancaster T.

Cochrane Database Syst Rev. 2012 Dec 12;12:CD009670. doi: 10.1002/14651858.CD009670.pub2. Review. Update in: Cochrane Database Syst Rev. 2015;10:CD009670.

PMID:
23235680
39.

The transcriptional consequences of somatic amplifications, deletions, and rearrangements in a human lung squamous cell carcinoma.

Stead LF, Berri S, Wood HM, Egan P, Conway C, Daly C, Papagiannopoulos K, Rabbitts P.

Neoplasia. 2012 Nov;14(11):1075-86.

40.

Nicotine replacement therapy for smoking cessation.

Stead LF, Perera R, Bullen C, Mant D, Hartmann-Boyce J, Cahill K, Lancaster T.

Cochrane Database Syst Rev. 2012 Nov 14;11:CD000146. doi: 10.1002/14651858.CD000146.pub4. Review. Update in: Cochrane Database Syst Rev. 2018 May 31;5:CD000146.

PMID:
23152200
41.

Combined pharmacotherapy and behavioural interventions for smoking cessation.

Stead LF, Lancaster T.

Cochrane Database Syst Rev. 2012 Oct 17;10:CD008286. doi: 10.1002/14651858.CD008286.pub2. Review. Update in: Cochrane Database Syst Rev. 2016;3:CD008286.

PMID:
23076944
42.

Silver acetate for smoking cessation.

Lancaster T, Stead LF.

Cochrane Database Syst Rev. 2012 Sep 12;(9):CD000191. doi: 10.1002/14651858.CD000191.pub2. Review.

PMID:
22972041
43.

Mutation detection by clonal sequencing of PCR amplicons and grouped read typing is applicable to clinical diagnostics.

Chambers PA, Stead LF, Morgan JE, Carr IM, Sutton KM, Watson CM, Crowe V, Dickinson H, Roberts P, Mulatero C, Seymour M, Markham AF, Waring PM, Quirke P, Taylor GR.

Hum Mutat. 2013 Jan;34(1):248-54. doi: 10.1002/humu.22207. Epub 2012 Oct 11.

PMID:
22915446
44.

Interventions for smoking cessation in hospitalised patients.

Rigotti NA, Clair C, Munafò MR, Stead LF.

Cochrane Database Syst Rev. 2012 May 16;(5):CD001837. doi: 10.1002/14651858.CD001837.pub3. Review.

45.

Nicotine receptor partial agonists for smoking cessation.

Cahill K, Stead LF, Lancaster T.

Cochrane Database Syst Rev. 2012 Apr 18;(4):CD006103. doi: 10.1002/14651858.CD006103.pub6. Review. Update in: Cochrane Database Syst Rev. 2016;(5):CD006103.

PMID:
22513936
46.

Lobeline for smoking cessation.

Stead LF, Hughes JR.

Cochrane Database Syst Rev. 2012 Feb 15;(2):CD000124. doi: 10.1002/14651858.CD000124.pub2. Review.

PMID:
22336780
47.

Impact of tobacco advertising and promotion on increasing adolescent smoking behaviours.

Lovato C, Watts A, Stead LF.

Cochrane Database Syst Rev. 2011 Oct 5;(10):CD003439. doi: 10.1002/14651858.CD003439.pub2. Review.

PMID:
21975739
48.

KvSNP: accurately predicting the effect of genetic variants in voltage-gated potassium channels.

Stead LF, Wood IC, Westhead DR.

Bioinformatics. 2011 Aug 15;27(16):2181-6. doi: 10.1093/bioinformatics/btr365. Epub 2011 Jun 17.

PMID:
21685056
49.

Nicotine receptor partial agonists for smoking cessation.

Cahill K, Stead LF, Lancaster T.

Cochrane Database Syst Rev. 2011 Feb 16;(2):CD006103. doi: 10.1002/14651858.CD006103.pub5. Review. Update in: Cochrane Database Syst Rev. 2012;4:CD006103.

PMID:
21328282
50.

Interventions for smokeless tobacco use cessation.

Ebbert J, Montori VM, Erwin PJ, Stead LF.

Cochrane Database Syst Rev. 2011 Feb 16;(2):CD004306. doi: 10.1002/14651858.CD004306.pub4. Review. Update in: Cochrane Database Syst Rev. 2015;10:CD004306.

PMID:
21328266

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