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Items: 1 to 50 of 194

1.

Glycan targeted polymeric antibiotic prodrugs for alveolar macrophage infections.

Chen J, Su FY, Das D, Srinivasan S, Son HN, Lee B, Radella F 2nd, Whittington D, Monroe-Jones T, West TE, Convertine AJ, Skerrett SJ, Stayton PS, Ratner DM.

Biomaterials. 2019 Mar;195:38-50. doi: 10.1016/j.biomaterials.2018.10.017. Epub 2018 Oct 16.

PMID:
30610992
2.

Temperature-Responsive Magnetic Nanoparticles for Enabling Affinity Separation of Extracellular Vesicles.

Jauregui R, Srinivasan S, Vojtech LN, Gammill HS, Chiu DT, Hladik F, Stayton PS, Lai JJ.

ACS Appl Mater Interfaces. 2018 Oct 10;10(40):33847-33856. doi: 10.1021/acsami.8b09751. Epub 2018 Sep 27.

3.

Macrophage-targeted drugamers with enzyme-cleavable linkers deliver high intracellular drug dosing and sustained drug pharmacokinetics against alveolar pulmonary infections.

Su FY, Srinivasan S, Lee B, Chen J, Convertine AJ, West TE, Ratner DM, Skerrett SJ, Stayton PS.

J Control Release. 2018 Oct 10;287:1-11. doi: 10.1016/j.jconrel.2018.08.014. Epub 2018 Aug 9.

4.

Polymer-augmented liposomes enhancing antibiotic delivery against intracellular infections.

Su FY, Chen J, Son HN, Kelly AM, Convertine AJ, West TE, Skerrett SJ, Ratner DM, Stayton PS.

Biomater Sci. 2018 Jun 25;6(7):1976-1985. doi: 10.1039/c8bm00282g.

5.

Core-Cross-Linked Nanoparticles Reduce Neuroinflammation and Improve Outcome in a Mouse Model of Traumatic Brain Injury.

Yoo D, Magsam AW, Kelly AM, Stayton PS, Kievit FM, Convertine AJ.

ACS Nano. 2017 Sep 26;11(9):8600-8611. doi: 10.1021/acsnano.7b03426. Epub 2017 Aug 16.

PMID:
28783305
6.

Orientation and conformation of osteocalcin adsorbed onto calcium phosphate and silica surfaces.

Scudeller LA, Srinivasan S, Rossi AM, Stayton PS, Drobny GP, Castner DG.

Biointerphases. 2017 May 18;12(2):02D411. doi: 10.1116/1.4983407.

7.

Synthetic Macromolecular Antibiotic Platform for Inhalable Therapy against Aerosolized Intracellular Alveolar Infections.

Das D, Chen J, Srinivasan S, Kelly AM, Lee B, Son HN, Radella F, West TE, Ratner DM, Convertine AJ, Skerrett SJ, Stayton PS.

Mol Pharm. 2017 Jun 5;14(6):1988-1997. doi: 10.1021/acs.molpharmaceut.7b00093. Epub 2017 May 9.

PMID:
28394614
8.

Enzyme-Cleavable Polymeric Micelles for the Intracellular Delivery of Proapoptotic Peptides.

Kern HB, Srinivasan S, Convertine AJ, Hockenbery D, Press OW, Stayton PS.

Mol Pharm. 2017 May 1;14(5):1450-1459. doi: 10.1021/acs.molpharmaceut.6b01178. Epub 2017 Mar 30.

9.

Reloadable multidrug capturing delivery system for targeted ischemic disease treatment.

Wu JP, Cheng B, Roffler SR, Lundy DJ, Yen CY, Chen P, Lai JJ, Pun SH, Stayton PS, Hsieh PC.

Sci Transl Med. 2016 Nov 16;8(365):365ra160.

PMID:
27856799
10.

Computationally designed high specificity inhibitors delineate the roles of BCL2 family proteins in cancer.

Berger S, Procko E, Margineantu D, Lee EF, Shen BW, Zelter A, Silva DA, Chawla K, Herold MJ, Garnier JM, Johnson R, MacCoss MJ, Lessene G, Davis TN, Stayton PS, Stoddard BL, Fairlie WD, Hockenbery DM, Baker D.

Elife. 2016 Nov 2;5. pii: e20352. doi: 10.7554/eLife.20352.

11.

A Stimuli-Responsive, Binary Reagent System for Rapid Isolation of Protein Biomarkers.

Nehilla BJ, Hill JJ, Srinivasan S, Chen YC, Schulte TH, Stayton PS, Lai JJ.

Anal Chem. 2016 Nov 1;88(21):10404-10410. Epub 2016 Oct 14.

12.

A Streptavidin Binding Site Mutation Yields an Unexpected Result: An Ionized Asp128 Residue Is Not Essential for Strong Biotin Binding.

Baugh L, Le Trong I, Stayton PS, Stenkamp RE, Lybrand TP.

Biochemistry. 2016 Sep 20;55(37):5201-3. doi: 10.1021/acs.biochem.6b00698. Epub 2016 Sep 8.

13.

Editorial.

Pun SH, Stayton PS.

J Control Release. 2016 Jun 10;231:1. doi: 10.1016/j.jconrel.2016.05.005. No abstract available.

PMID:
27184184
14.

Nanostructured glycopolymer augmented liposomes to elucidate carbohydrate-mediated targeting.

Chen J, Son HN, Hill JJ, Srinivasan S, Su FY, Stayton PS, Convertine AJ, Ratner DM.

Nanomedicine. 2016 Oct;12(7):2031-2041. doi: 10.1016/j.nano.2016.05.001. Epub 2016 May 14.

PMID:
27184097
15.

Antibody targeting facilitates effective intratumoral siRNA nanoparticle delivery to HER2-overexpressing cancer cells.

Palanca-Wessels MC, Booth GC, Convertine AJ, Lundy BB, Berguig GY, Press MF, Stayton PS, Press OW.

Oncotarget. 2016 Feb 23;7(8):9561-75. doi: 10.18632/oncotarget.7076.

16.

Three-dimensional localization of polymer nanoparticles in cells using ToF-SIMS.

Graham DJ, Wilson JT, Lai JJ, Stayton PS, Castner DG.

Biointerphases. 2015 Jun 3;11(2):02A304. doi: 10.1116/1.4934795.

17.

Nanoparticle distribution during systemic inflammation is size-dependent and organ-specific.

Chen KH, Lundy DJ, Toh EK, Chen CH, Shih C, Chen P, Chang HC, Lai JJ, Stayton PS, Hoffman AS, Hsieh PC.

Nanoscale. 2015 Oct 14;7(38):15863-72. doi: 10.1039/c5nr03626g. Epub 2015 Sep 11.

PMID:
26359216
18.

Polymer nanostructures synthesized by controlled living polymerization for tumor-targeted drug delivery.

Wang CE, Stayton PS, Pun SH, Convertine AJ.

J Control Release. 2015 Dec 10;219:345-354. doi: 10.1016/j.jconrel.2015.08.054. Epub 2015 Sep 2. Review.

19.

Well-defined single polymer nanoparticles for the antibody-targeted delivery of chemotherapeutic agents.

Lane DD, Chiu DY, Su FY, Srinivasan S, Kern HB, Press OW, Stayton PS, Convertine AJ.

Polym Chem. 2015 Feb 28;6(8):1286-1299.

20.

Dynamic intracellular delivery of antibiotics via pH-responsive polymersomes.

Lane DD, Su FY, Chiu DY, Srinivasan S, Wilson JT, Ratner DM, Stayton PS, Convertine AJ.

Polym Chem. 2015 Feb 28;6(8):1255-1266.

21.

Intracellular delivery system for antibody-Peptide drug conjugates.

Berguig GY, Convertine AJ, Frayo S, Kern HB, Procko E, Roy D, Srinivasan S, Margineantu DH, Booth G, Palanca-Wessels MC, Baker D, Hockenbery D, Press OW, Stayton PS.

Mol Ther. 2015 May;23(5):907-917. doi: 10.1038/mt.2015.22. Epub 2015 Feb 11.

22.

Improving lateral-flow immunoassay (LFIA) diagnostics via biomarker enrichment for mHealth.

Lai JJ, Stayton PS.

Methods Mol Biol. 2015;1256:71-84. doi: 10.1007/978-1-4939-2172-0_5.

PMID:
25626532
23.

Enhancement of MHC-I antigen presentation via architectural control of pH-responsive, endosomolytic polymer nanoparticles.

Wilson JT, Postma A, Keller S, Convertine AJ, Moad G, Rizzardo E, Meagher L, Chiefari J, Stayton PS.

AAPS J. 2015 Mar;17(2):358-69. doi: 10.1208/s12248-014-9697-1. Epub 2014 Dec 12.

24.

Stimuli-responsive reagent system for enabling microfluidic immunoassays with biomarker purification and enrichment.

Hoffman JM, Stayton PS, Hoffman AS, Lai JJ.

Bioconjug Chem. 2015 Jan 21;26(1):29-38. doi: 10.1021/bc500522k. Epub 2014 Dec 24.

25.
26.

A computationally designed inhibitor of an Epstein-Barr viral Bcl-2 protein induces apoptosis in infected cells.

Procko E, Berguig GY, Shen BW, Song Y, Frayo S, Convertine AJ, Margineantu D, Booth G, Correia BE, Cheng Y, Schief WR, Hockenbery DM, Press OW, Stoddard BL, Stayton PS, Baker D.

Cell. 2014 Jun 19;157(7):1644-1656. doi: 10.1016/j.cell.2014.04.034.

27.

Design of smart nanogels that respond to physiologically relevant pH values and temperatures.

Omura T, Ebara M, Lai JJ, Yin X, Hoffman AS, Stayton PS.

J Nanosci Nanotechnol. 2014 Mar;14(3):2557-62.

PMID:
24745263
28.

Neutral polymer micelle carriers with pH-responsive, endosome-releasing activity modulate antigen trafficking to enhance CD8(+) T cell responses.

Keller S, Wilson JT, Patilea GI, Kern HB, Convertine AJ, Stayton PS.

J Control Release. 2014 Oct 10;191:24-33. doi: 10.1016/j.jconrel.2014.03.041. Epub 2014 Mar 31.

29.

TOF-SIMS 3D imaging of native and non-native species within HeLa cells.

Brison J, Robinson MA, Benoit DS, Muramoto S, Stayton PS, Castner DG.

Anal Chem. 2013 Nov 19;85(22):10869-77. doi: 10.1021/ac402288d. Epub 2013 Nov 5.

30.

Structural consequences of cutting a binding loop: two circularly permuted variants of streptavidin.

Le Trong I, Chu V, Xing Y, Lybrand TP, Stayton PS, Stenkamp RE.

Acta Crystallogr D Biol Crystallogr. 2013 Jun;69(Pt 6):968-77. doi: 10.1107/S0907444913003855. Epub 2013 May 11.

31.

Functionalized nanoparticles provide early cardioprotection after acute myocardial infarction.

Chang MY, Yang YJ, Chang CH, Tang AC, Liao WY, Cheng FY, Yeh CS, Lai JJ, Stayton PS, Hsieh PC.

J Control Release. 2013 Sep 10;170(2):287-94. doi: 10.1016/j.jconrel.2013.04.022. Epub 2013 May 9.

PMID:
23665256
32.

pH-Responsive nanoparticle vaccines for dual-delivery of antigens and immunostimulatory oligonucleotides.

Wilson JT, Keller S, Manganiello MJ, Cheng C, Lee CC, Opara C, Convertine A, Stayton PS.

ACS Nano. 2013 May 28;7(5):3912-25. doi: 10.1021/nn305466z. Epub 2013 Apr 30.

33.

A photoinduced nanoparticle separation in microchannels via pH-sensitive surface traps.

Ebara M, Hoffman JM, Hoffman AS, Stayton PS, Lai JJ.

Langmuir. 2013 May 7;29(18):5388-93. doi: 10.1021/la400347r. Epub 2013 Apr 24.

34.

Neutral polymeric micelles for RNA delivery.

Lundy BB, Convertine A, Miteva M, Stayton PS.

Bioconjug Chem. 2013 Mar 20;24(3):398-407. doi: 10.1021/bc300486k. Epub 2013 Feb 22.

35.

Melittin-grafted HPMA-oligolysine based copolymers for gene delivery.

Schellinger JG, Pahang JA, Johnson RN, Chu DS, Sellers DL, Maris DO, Convertine AJ, Stayton PS, Horner PJ, Pun SH.

Biomaterials. 2013 Mar;34(9):2318-26. doi: 10.1016/j.biomaterials.2012.09.072. Epub 2012 Dec 20.

36.

Intracellular delivery and trafficking dynamics of a lymphoma-targeting antibody-polymer conjugate.

Berguig GY, Convertine AJ, Shi J, Palanca-Wessels MC, Duvall CL, Pun SH, Press OW, Stayton PS.

Mol Pharm. 2012 Dec 3;9(12):3506-14. doi: 10.1021/mp300338s. Epub 2012 Nov 5.

37.

Multiplexed enrichment and detection of malarial biomarkers using a stimuli-responsive iron oxide and gold nanoparticle reagent system.

Nash MA, Waitumbi JN, Hoffman AS, Yager P, Stayton PS.

ACS Nano. 2012 Aug 28;6(8):6776-85. doi: 10.1021/nn3015008. Epub 2012 Jul 24.

38.

Multifunctional triblock copolymers for intracellular messenger RNA delivery.

Cheng C, Convertine AJ, Stayton PS, Bryers JD.

Biomaterials. 2012 Oct;33(28):6868-76. doi: 10.1016/j.biomaterials.2012.06.020. Epub 2012 Jul 9.

39.

In vivo targeting of alveolar macrophages via RAFT-based glycopolymers.

Song EH, Manganiello MJ, Chow YH, Ghosn B, Convertine AJ, Stayton PS, Schnapp LM, Ratner DM.

Biomaterials. 2012 Oct;33(28):6889-97. doi: 10.1016/j.biomaterials.2012.06.025. Epub 2012 Jul 6.

40.

Application of living free radical polymerization for nucleic acid delivery.

Chu DS, Schellinger JG, Shi J, Convertine AJ, Stayton PS, Pun SH.

Acc Chem Res. 2012 Jul 17;45(7):1089-99. doi: 10.1021/ar200242z. Epub 2012 Jan 13.

41.

Diblock copolymers with tunable pH transitions for gene delivery.

Manganiello MJ, Cheng C, Convertine AJ, Bryers JD, Stayton PS.

Biomaterials. 2012 Mar;33(7):2301-9. doi: 10.1016/j.biomaterials.2011.11.019. Epub 2011 Dec 12.

42.

Probing the orientation of electrostatically immobilized Protein G B1 by time-of-flight secondary ion spectrometry, sum frequency generation, and near-edge X-ray adsorption fine structure spectroscopy.

Baio JE, Weidner T, Baugh L, Gamble LJ, Stayton PS, Castner DG.

Langmuir. 2012 Jan 31;28(4):2107-12. doi: 10.1021/la203907t. Epub 2011 Dec 22.

43.

Second-contact shell mutation diminishes streptavidin-biotin binding affinity through transmitted effects on equilibrium dynamics.

Baugh L, Le Trong I, Cerutti DS, Mehta N, G├╝lich S, Stayton PS, Stenkamp RE, Lybrand TP.

Biochemistry. 2012 Jan 17;51(2):597-607. doi: 10.1021/bi201221j. Epub 2012 Jan 3.

44.

ToF-SIMS imaging and depth profiling of HeLa cells treated with bromodeoxyuridine.

Brison J, Benoit DS, Muramoto S, Robinson M, Stayton PS, Castner DG.

Surf Interface Anal. 2011 Jan;43(1-2):354-357.

45.

Pretargeted radioimmunotherapy using genetically engineered antibody-streptavidin fusion proteins for treatment of non-hodgkin lymphoma.

Park SI, Shenoi J, Frayo SM, Hamlin DK, Lin Y, Wilbur DS, Stayton PS, Orgun N, Hylarides M, Buchegger F, Kenoyer AL, Axtman A, Gopal AK, Green DJ, Pagel JM, Press OW.

Clin Cancer Res. 2011 Dec 1;17(23):7373-82. doi: 10.1158/1078-0432.CCR-11-1204. Epub 2011 Oct 5.

46.

Streptavidin and its biotin complex at atomic resolution.

Le Trong I, Wang Z, Hyre DE, Lybrand TP, Stayton PS, Stenkamp RE.

Acta Crystallogr D Biol Crystallogr. 2011 Sep;67(Pt 9):813-21. doi: 10.1107/S0907444911027806. Epub 2011 Aug 9.

47.

RAFT-synthesized graft copolymers that enhance pH-dependent membrane destabilization and protein circulation times.

Crownover E, Duvall CL, Convertine A, Hoffman AS, Stayton PS.

J Control Release. 2011 Oct 30;155(2):167-74. doi: 10.1016/j.jconrel.2011.06.013. Epub 2011 Jun 15.

48.

Synthesis of folate-functionalized RAFT polymers for targeted siRNA delivery.

Benoit DS, Srinivasan S, Shubin AD, Stayton PS.

Biomacromolecules. 2011 Jul 11;12(7):2708-14. doi: 10.1021/bm200485b. Epub 2011 Jun 10.

49.

Anti-CD22 antibody targeting of pH-responsive micelles enhances small interfering RNA delivery and gene silencing in lymphoma cells.

Palanca-Wessels MC, Convertine AJ, Cutler-Strom R, Booth GC, Lee F, Berguig GY, Stayton PS, Press OW.

Mol Ther. 2011 Aug;19(8):1529-37. doi: 10.1038/mt.2011.104. Epub 2011 May 31.

50.

Efficient Intracellular Delivery of a Pro-Apoptotic Peptide With A pH-Responsive Carrier.

Albarran B, Hoffman AS, Stayton PS.

React Funct Polym. 2011 Mar 1;71(3):261-265.

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