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Chronic Elevation of Endothelin-1 Alone May Not Be Sufficient to Impair Endothelium-Dependent Relaxation.

Grunewald ZI, Jurrissen TJ, Woodford ML, Ramirez-Perez FI, Park LK, Pettit-Mee R, Ghiarone T, Brown SM, Morales-Quinones M, Ball JR, Staveley-O'Carroll KF, Aroor AR, Fadel PJ, Paradis P, Schiffrin EL, Bender SB, Martinez-Lemus LA, Padilla J.

Hypertension. 2019 Dec;74(6):1409-1419. doi: 10.1161/HYPERTENSIONAHA.119.13676. Epub 2019 Oct 21.


An Oncogenic Hepatocyte-Induced Orthotopic Mouse Model of Hepatocellular Cancer Arising in the Setting of Hepatic Inflammation and Fibrosis.

Qi X, Schepers E, Avella D, Kimchi ET, Kaifi JT, Staveley-O'Carroll KF, Li G.

J Vis Exp. 2019 Sep 12;(151). doi: 10.3791/59368.


Circulating tumor cell clusters are a potential biomarker for detection of non-small cell lung cancer.

Manjunath Y, Upparahalli SV, Suvilesh KN, Avella DM, Kimchi ET, Staveley-O'Carroll KF, Li G, Kaifi JT.

Lung Cancer. 2019 Aug;134:147-150. doi: 10.1016/j.lungcan.2019.06.016. Epub 2019 Jun 17.


Overproduction of endothelin-1 impairs glucose tolerance but does not promote visceral adipose tissue inflammation or limit metabolic adaptations to exercise.

Jurrissen TJ, Grunewald ZI, Woodford ML, Winn NC, Ball JR, Smith TN, Wheeler AA, Rawlings AL, Staveley-O'Carroll KF, Ji Y, Fay WP, Paradis P, Schiffrin EL, Vieira-Potter VJ, Fadel PJ, Martinez-Lemus LA, Padilla J.

Am J Physiol Endocrinol Metab. 2019 Sep 1;317(3):E548-E558. doi: 10.1152/ajpendo.00178.2019. Epub 2019 Jul 16.


PD-L1 Expression with Epithelial Mesenchymal Transition of Circulating Tumor Cells Is Associated with Poor Survival in Curatively Resected Non-Small Cell Lung Cancer.

Manjunath Y, Upparahalli SV, Avella DM, Deroche CB, Kimchi ET, Staveley-O'Carroll KF, Smith CJ, Li G, Kaifi JT.

Cancers (Basel). 2019 Jun 11;11(6). pii: E806. doi: 10.3390/cancers11060806.


Targeted and Immune-Based Therapies for Hepatocellular Carcinoma.

Greten TF, Lai CW, Li G, Staveley-O'Carroll KF.

Gastroenterology. 2019 Jan;156(2):510-524. doi: 10.1053/j.gastro.2018.09.051. Epub 2018 Oct 1. Review.


Sunitinib and Sorafenib Modulating Antitumor Immunity in Hepatocellular Cancer.

Liu D, Qi X, Manjunath Y, Kimchi ET, Ma L, Kaifi JT, Staveley-O'Carroll KF, Li G.

J Immunol Res Ther. 2018;3(1):115-123. Epub 2018 Jun 8.


Nanoliposome C6-Ceramide Increases the Anti-tumor Immune Response and Slows Growth of Liver Tumors in Mice.

Li G, Liu D, Kimchi ET, Kaifi JT, Qi X, Manjunath Y, Liu X, Deering T, Avella DM, Fox T, Rockey DC, Schell TD, Kester M, Staveley-O'Carroll KF.

Gastroenterology. 2018 Mar;154(4):1024-1036.e9. doi: 10.1053/j.gastro.2017.10.050. Epub 2018 Jan 31.


Sunitinib represses regulatory T cells to overcome immunotolerance in a murine model of hepatocellular cancer.

Liu D, Li G, Avella DM, Kimchi ET, Kaifi JT, Rubinstein MP, Camp ER, Rockey DC, Schell TD, Staveley-O'Carroll KF.

Oncoimmunology. 2017 Sep 21;7(1):e1372079. doi: 10.1080/2162402X.2017.1372079. eCollection 2017.


Antibody-mediated neutralization of soluble MIC significantly enhances CTLA4 blockade therapy.

Zhang J, Liu D, Li G, Staveley-O'Carroll KF, Graff JN, Li Z, Wu JD.

Sci Adv. 2017 May 17;3(5):e1602133. doi: 10.1126/sciadv.1602133. eCollection 2017 May.


Galectin-1-driven upregulation of SDF-1 in pancreatic stellate cells promotes pancreatic cancer metastasis.

Qian D, Lu Z, Xu Q, Wu P, Tian L, Zhao L, Cai B, Yin J, Wu Y, Staveley-O'Carroll KF, Jiang K, Miao Y, Li G.

Cancer Lett. 2017 Jul 1;397:43-51. doi: 10.1016/j.canlet.2017.03.024. Epub 2017 Mar 21.


Potential of Radiofrequency Ablation in Combination with Immunotherapy in the Treatment of Hepatocellular Carcinoma.

Li G, Staveley-O'Carroll KF, Kimchi ET.

J Clin Trials. 2016 Apr;6(2). pii: 257. doi: 10.4172/2167-0870.1000257. Epub 2016 Apr 5.


Development of inCVAX, In situ Cancer Vaccine, and Its Immune Response in Mice with Hepatocellular Cancer.

Qi X, Lam SS, Liu D, Kim DY, Ma L, Alleruzzo L, Chen W, Hode T, Henry CJ, Kaifi J, Kimchi ET, Li G, Staveley-O'Carroll KF.

J Clin Cell Immunol. 2016 Aug;7(4). pii: 438. doi: 10.4172/2155-9899.1000438. Epub 2016 Jul 18.


Successful chemoimmunotherapy against hepatocellular cancer in a novel murine model.

Li G, Liu D, Cooper TK, Kimchi ET, Qi X, Avella DM, Li N, Yang QX, Kester M, Rountree CB, Kaifi JT, Cole DJ, Rockey DC, Schell TD, Staveley-O'Carroll KF.

J Hepatol. 2017 Jan;66(1):75-85. doi: 10.1016/j.jhep.2016.07.044. Epub 2016 Aug 9.


The impact of metabolic syndrome on outcome and response to neoadjuvant chemoradiation in locally advanced rectal cancer patients.

Anderson BJ, Wahlquist AE, Hill EG, Marshall DT, Kimchi ET, Staveley O'Carroll KF, Camp ER.

Int J Surg. 2016 Sep;33 Pt A:8-12. doi: 10.1016/j.ijsu.2016.07.011. Epub 2016 Jul 16.


Qualities and characteristics of successfully matched North American HPB surgery fellowship candidates.

Baker EH, Dowden JE, Cochran AR, Iannitti DA, Kimchi ET, Staveley-O'Carroll KF, Jeyarajah DR.

HPB (Oxford). 2016 May;18(5):479-84. doi: 10.1016/j.hpb.2015.12.001. Epub 2016 Feb 18.


Perioperative circulating tumor cell detection: Current perspectives.

Kaifi JT, Li G, Clawson G, Kimchi ET, Staveley-O'Carroll KF.

Cancer Biol Ther. 2016 Aug 2;17(8):859-69. doi: 10.1080/15384047.2016.1167296. Epub 2016 Apr 5. Review.


A Selenium Containing Inhibitor for the Treatment of Hepatocellular Cancer.

Tagaram HR, Desai D, Li G, Liu D, Rountree CB, Gowda K, Berg A, Amin S, Staveley-O'Carroll KF, Kimchi ET.

Pharmaceuticals (Basel). 2016 Mar 24;9(2). pii: E18. doi: 10.3390/ph9020018.


Immune-based Therapy Clinical Trials in Hepatocellular Carcinoma.

Liu D, Staveley-O'Carroll KF, Li G.

J Clin Cell Immunol. 2015 Dec;6(6). pii: 376. Epub 2015 Dec 10.


Central Pancreatectomy with Pancreaticogastrostomy for the Treatment of a Solid-pseudopapillary Neoplasm.

Dowden JE, Kimchi ET, Camp ER, Morgan KA, Adams DB, Staveley-O'Carroll KF.

Am Surg. 2015 Nov;81(11):E383-4. No abstract available.


Ampullary Gangliocytic Paraganglioma with Lymph Node Metastasis.

Dowden JE, Staveley-O'Carroll KF, Kimchi ET, Camp ER, Morgan KA, Adams DB.

Am Surg. 2015 Nov;81(11):E359-60. No abstract available.


Advances in the Pharmacologic Treatment of Hepatocellular Carcinoma.

Bhayani NH, Jiang Y, Hamed O, Kimchi ET, Staveley-O'Carroll KF, Gusani NJ.

Curr Clin Pharmacol. 2015;10(4):299-304. Review.


Development of a radiofrequency ablation platform in a clinically relevant murine model of hepatocellular cancer.

Qi X, Li G, Liu D, Motamarry A, Huang X, Wolfe AM, Helke KL, Haemmerich D, Staveley-O'Carroll KF, Kimchi ET.

Cancer Biol Ther. 2015;16(12):1812-9. doi: 10.1080/15384047.2015.1095412.


Effector CD8+ T-cell Engraftment and Antitumor Immunity in Lymphodepleted Hosts Is IL7Rα Dependent.

Johnson CB, Riesenberg BP, May BR, Gilreath SC, Li G, Staveley-O'Carroll KF, Garrett-Mayer E, Mehrotra S, Cole DJ, Rubinstein MP.

Cancer Immunol Res. 2015 Dec;3(12):1364-74. doi: 10.1158/2326-6066.CIR-15-0087-T. Epub 2015 Aug 21.


Nonblocking Monoclonal Antibody Targeting Soluble MIC Revamps Endogenous Innate and Adaptive Antitumor Responses and Eliminates Primary and Metastatic Tumors.

Lu S, Zhang J, Liu D, Li G, Staveley-O'Carroll KF, Li Z, Wu JD.

Clin Cancer Res. 2015 Nov 1;21(21):4819-30. doi: 10.1158/1078-0432.CCR-15-0845. Epub 2015 Jun 23.


The impact of surgical diversion before neoadjuvant therapy for rectal cancer.

Anderson BJ, Hill EG, Sweeney RE, Wahlquist AE, Marshall DT, Staveley O'Carroll KF, Cole DJ, Camp ER.

Am Surg. 2015 May;81(5):444-9.


Pleural space infections after image-guided percutaneous drainage of infected intraabdominal fluid collections: a retrospective single institution analysis.

Avella DM, Toth JW, Reed MF, Gusani NJ, Kimchi ET, Mahraj RP, Staveley-O'Carroll KF, Kaifi JT.

BMC Surg. 2015 Apr 11;15:42. doi: 10.1186/s12893-015-0030-4.


Circulating tumor cell isolation during resection of colorectal cancer lung and liver metastases: a prospective trial with different detection techniques.

Kaifi JT, Kunkel M, Das A, Harouaka RA, Dicker DT, Li G, Zhu J, Clawson GA, Yang Z, Reed MF, Gusani NJ, Kimchi ET, Staveley-O'Carroll KF, Zheng SY, El-Deiry WS.

Cancer Biol Ther. 2015;16(5):699-708. doi: 10.1080/15384047.2015.1030556.


Circulating tumor cell levels are elevated in colorectal cancer patients with high tumor burden in the liver.

Kaifi JT, Kunkel M, Dicker DT, Joude J, Allen JE, Das A, Zhu J, Yang Z, Sarwani NE, Li G, Staveley-O'Carroll KF, El-Deiry WS.

Cancer Biol Ther. 2015;16(5):690-8. doi: 10.1080/15384047.2015.1026508.


SNAI2 modulates colorectal cancer 5-fluorouracil sensitivity through miR145 repression.

Findlay VJ, Wang C, Nogueira LM, Hurst K, Quirk D, Ethier SP, Staveley O'Carroll KF, Watson DK, Camp ER.

Mol Cancer Ther. 2014 Nov;13(11):2713-26. doi: 10.1158/1535-7163.MCT-14-0207. Epub 2014 Sep 23.


Determinants of repeat curative intent surgery in colorectal liver metastasis.

Kulaylat AN, Bhayani NH, Stokes AL, Schubart JR, Wong J, Kimchi ET, Staveley-O'Carroll KF, Kaifi JT, Gusani NJ.

J Gastrointest Surg. 2014 Nov;18(11):1894-901. doi: 10.1007/s11605-014-2580-7. Epub 2014 Jun 21.


Phase I dose escalation study of capecitabine and erlotinib concurrent with radiation in locally advanced pancreatic cancer.

Jiang Y, Mackley HB, Kimchi ET, Zhu J, Gusani N, Kaifi J, Staveley-O'Carroll KF, Belani CP.

Cancer Chemother Pharmacol. 2014 Jul;74(1):205-10. doi: 10.1007/s00280-014-2488-7. Epub 2014 Jun 8.


Multivisceral and extended resections during pancreatoduodenectomy increase morbidity and mortality.

Bhayani NH, Enomoto LM, James BC, Ortenzi G, Kaifi JT, Kimchi ET, Staveley-O'Carroll KF, Gusani NJ.

Surgery. 2014 Mar;155(3):567-74. doi: 10.1016/j.surg.2013.12.020. Epub 2013 Dec 25.


Perioperative outcomes of pancreaticoduodenectomy compared to total pancreatectomy for neoplasia.

Bhayani NH, Miller JL, Ortenzi G, Kaifi JT, Kimchi ET, Staveley-O'Carroll KF, Gusani NJ.

J Gastrointest Surg. 2014 Mar;18(3):549-54. doi: 10.1007/s11605-013-2393-0. Epub 2013 Oct 29.


Circulating tumor cells are associated with diffuse spread in stage IV colorectal cancer patients.

Kaifi JT, Kunkel M, Zhu J, Dicker DT, Gusani N, Yang Z, Sarwani NE, Li G, Kimchi ET, Staveley-O'Carroll KF, El-Deiry WS.

Cancer Biol Ther. 2013 Dec;14(12):1174-81. doi: 10.4161/cbt.26884. Epub 2013 Oct 23.


Morbidity of total pancreatectomy with islet cell auto-transplantation compared to total pancreatectomy alone.

Bhayani NH, Enomoto LM, Miller JL, Ortenzi G, Kaifi JT, Kimchi ET, Staveley-O'Carroll KF, Gusani NJ.

HPB (Oxford). 2014 Jun;16(6):522-7. doi: 10.1111/hpb.12168. Epub 2013 Aug 29.


Reconstructive options for gastroesophageal junction adenocarcinoma after Roux-en-Y gastric bypass.

Kulaylat AN, Sahajwani S, Staveley-O'Carroll KF, Kaifi JT.

J Thorac Cardiovasc Surg. 2013 Nov;146(5):1296-8. doi: 10.1016/j.jtcvs.2013.07.007. Epub 2013 Aug 26. No abstract available.


Do patients' outcomes suffer when surgical fellows are involved in hepatic resection?

Bhayani NH, Hamed OH, Gupta A, Ortenzi G, Kaifi JT, Kimchi ET, Staveley-O'Carroll KF, Gusani NJ.

Surgery. 2013 Nov;154(5):1024-30. doi: 10.1016/j.surg.2013.05.024. Epub 2013 Jul 25.


Lymphoepithelial cysts of the pancreas. Can preoperative imaging distinguish this benign lesion from malignant or pre-malignant cystic pancreatic lesions?

Kavuturu S, Sarwani NE, Ruggeiro FM, Deshaies I, Kimchi ET, Kaifi JT, Staveley-O'Carroll KF, Gusani NJ.

JOP. 2013 May 10;14(3):250-5. doi: 10.6092/1590-8577/1229.


Scientific impact of Association for Academic Surgery and Society of University Surgeons plenary session abstracts increases in the era of the Academic Surgical Congress from 2006 to 2010.

Kaifi JT, Kibbe MR, LeMaire SA, Staveley-O'Carroll KF, Kao LS, Sosa JA, Kimchi ET, Pawlik TM, Gusani NJ.

J Surg Res. 2013 Jun 1;182(1):6-10. doi: 10.1016/j.jss.2012.08.021. Epub 2012 Aug 28.


A handy tool to teach segmental liver anatomy to surgical trainees.

Pauli EM, Staveley-O'Carroll KF, Brock MV, Efron DT, Efron G.

Arch Surg. 2012 Aug;147(8):692-3. doi: 10.1001/archsurg.2012.689. No abstract available.


Circulating tumor cells in melanoma patients.

Clawson GA, Kimchi E, Patrick SD, Xin P, Harouaka R, Zheng S, Berg A, Schell T, Staveley-O'Carroll KF, Neves RI, Mosca PJ, Thiboutot D.

PLoS One. 2012;7(7):e41052. doi: 10.1371/journal.pone.0041052. Epub 2012 Jul 19.


Budd-Chiari syndrome and post-traumatic diaphragmatic hernia.

Kaifi JT, Kavuturu S, Judelson D, Staveley-O'Carroll KF.

J Thorac Cardiovasc Surg. 2012 Apr;143(4):e21-2. doi: 10.1016/j.jtcvs.2012.01.041. Epub 2012 Feb 15. No abstract available.


Multidisciplinary management of malignant pleural effusion.

Kaifi JT, Toth JW, Gusani NJ, Kimchi ET, Staveley-O'Carroll KF, Belani CP, Reed MF.

J Surg Oncol. 2012 Jun 1;105(7):731-8. doi: 10.1002/jso.22100. Epub 2011 Sep 29. Review.


Regression of established hepatocellular carcinoma is induced by chemoimmunotherapy in an orthotopic murine model.

Avella DM, Li G, Schell TD, Liu D, Zhang SS, Lou X, Berg A, Kimchi ET, Tagaram HR, Yang Q, Shereef S, Garcia LS, Kester M, Isom HC, Rountree CB, Staveley-O'Carroll KF.

Hepatology. 2012 Jan;55(1):141-52. doi: 10.1002/hep.24652.


Combinatorial therapies improve the therapeutic efficacy of nanoliposomal ceramide for pancreatic cancer.

Jiang Y, DiVittore NA, Kaiser JM, Shanmugavelandy SS, Fritz JL, Heakal Y, Tagaram HR, Cheng H, Cabot MC, Staveley-O'Carroll KF, Tran MA, Fox TE, Barth BM, Kester M.

Cancer Biol Ther. 2011 Oct 1;12(7):574-85. Epub 2011 Oct 1.


Laparoscopic repair of post-esophagectomy diaphragmatic hernias using human acellular dermal matrix.

Avella DM, Podany A, Staveley-O'Carroll KF, Kaifi JT.

Interact Cardiovasc Thorac Surg. 2011 Aug;13(2):248-9. doi: 10.1510/icvts.2011.272310. Epub 2011 May 23.


Complete surgical resection of giant mucinous hepatic cystadenomas.

Nikfarjam M, Kimchi ET, Gusani NJ, Staveley-O'Carroll KF.

Am Surg. 2010 May;76(5):E17-9. No abstract available.


Multidisciplinary management of early and locally advanced esophageal cancer.

Kaifi JT, Gusani NJ, Jiang Y, Mackley HB, Dye CE, Mathew A, Kimchi ET, Reed MF, Staveley-O'Carroll KF.

J Clin Gastroenterol. 2011 May-Jun;45(5):391-9. doi: 10.1097/MCG.0b013e3182049949. Review.


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