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Items: 1 to 50 of 157

1.

Tissue Architectural Cues Drive Organ Targeting of Tumor Cells in Zebrafish.

Paul CD, Bishop K, Devine A, Paine EL, Staunton JR, Thomas SM, Thomas JR, Doyle AD, Miller Jenkins LM, Morgan NY, Sood R, Tanner K.

Cell Syst. 2019 Aug 28;9(2):187-206.e16. doi: 10.1016/j.cels.2019.07.005. Epub 2019 Aug 21.

PMID:
31445892
2.

High-frequency microrheology in 3D reveals mismatch between cytoskeletal and extracellular matrix mechanics.

Staunton JR, So WY, Paul CD, Tanner K.

Proc Natl Acad Sci U S A. 2019 Jul 16;116(29):14448-14455. doi: 10.1073/pnas.1814271116. Epub 2019 Jul 2.

PMID:
31266897
3.

Crystal field coefficients for yttrium analogues of rare-earth/transition-metal magnets using density-functional theory in the projector-augmented wave formalism.

Patrick CE, Staunton JB.

J Phys Condens Matter. 2019 Jul 31;31(30):305901. doi: 10.1088/1361-648X/ab18f3. Epub 2019 Apr 12.

PMID:
30978708
4.

Human macrophages survive and adopt activated genotypes in living zebrafish.

Paul CD, Devine A, Bishop K, Xu Q, Wulftange WJ, Burr H, Daly KM, Lewis C, Green DS, Staunton JR, Choksi S, Liu ZG, Sood R, Tanner K.

Sci Rep. 2019 Feb 11;9(1):1759. doi: 10.1038/s41598-018-38186-y.

5.

Probing cellular response to topography in three dimensions.

Paul CD, Hruska A, Staunton JR, Burr HA, Daly KM, Kim J, Jiang N, Tanner K.

Biomaterials. 2019 Mar;197:101-118. doi: 10.1016/j.biomaterials.2019.01.009. Epub 2019 Jan 8.

PMID:
30641262
6.

Field-induced canting of magnetic moments in GdCo5 at finite temperature: first-principles calculations and high-field measurements.

Patrick CE, Kumar S, Götze K, Pearce MJ, Singleton J, Rowlands G, Balakrishnan G, Lees MR, Goddard PA, Staunton JB.

J Phys Condens Matter. 2018 Aug 15;30(32):32LT01. doi: 10.1088/1361-648X/aad029. Epub 2018 Jun 29.

PMID:
29957599
7.

A comparison of methods to assess cell mechanical properties.

Wu PH, Aroush DR, Asnacios A, Chen WC, Dokukin ME, Doss BL, Durand-Smet P, Ekpenyong A, Guck J, Guz NV, Janmey PA, Lee JSH, Moore NM, Ott A, Poh YC, Ros R, Sander M, Sokolov I, Staunton JR, Wang N, Whyte G, Wirtz D.

Nat Methods. 2018 Jul;15(7):491-498. doi: 10.1038/s41592-018-0015-1. Epub 2018 Jun 18.

8.

Calculating the Magnetic Anisotropy of Rare-Earth-Transition-Metal Ferrimagnets.

Patrick CE, Kumar S, Balakrishnan G, Edwards RS, Lees MR, Petit L, Staunton JB.

Phys Rev Lett. 2018 Mar 2;120(9):097202. doi: 10.1103/PhysRevLett.120.097202.

PMID:
29547338
9.

Structure-based Design of Pyridone-Aminal eFT508 Targeting Dysregulated Translation by Selective Mitogen-activated Protein Kinase Interacting Kinases 1 and 2 (MNK1/2) Inhibition.

Reich SH, Sprengeler PA, Chiang GG, Appleman JR, Chen J, Clarine J, Eam B, Ernst JT, Han Q, Goel VK, Han EZR, Huang V, Hung INJ, Jemison A, Jessen KA, Molter J, Murphy D, Neal M, Parker GS, Shaghafi M, Sperry S, Staunton J, Stumpf CR, Thompson PA, Tran C, Webber SE, Wegerski CJ, Zheng H, Webster KR.

J Med Chem. 2018 Apr 26;61(8):3516-3540. doi: 10.1021/acs.jmedchem.7b01795. Epub 2018 Mar 29.

PMID:
29526098
10.

In situ calibration of position detection in an optical trap for active microrheology in viscous materials.

Staunton JR, Blehm B, Devine A, Tanner K.

Opt Express. 2017 Feb 6;25(3):1746-1761. doi: 10.1364/OE.25.001746.

11.

Hit-to-Lead Optimization and Discovery of 5-((5-([1,1'-Biphenyl]-4-yl)-6-chloro-1H-benzo[d]imidazol-2-yl)oxy)-2-methylbenzoic Acid (MK-3903): A Novel Class of Benzimidazole-Based Activators of AMP-Activated Protein Kinase.

Lan P, Romero FA, Wodka D, Kassick AJ, Dang Q, Gibson T, Cashion D, Zhou G, Chen Y, Zhang X, Zhang A, Li Y, Trujillo ME, Shao Q, Wu M, Xu S, He H, MacKenna D, Staunton J, Chapman KT, Weber A, Sebhat IK, Makara GM.

J Med Chem. 2017 Nov 9;60(21):9040-9052. doi: 10.1021/acs.jmedchem.7b01344. Epub 2017 Oct 25.

PMID:
29035567
12.

Theory of Magnetic Ordering in the Heavy Rare Earths: Ab Initio Electronic Origin of Pair- and Four-Spin Interactions.

Mendive-Tapia E, Staunton JB.

Phys Rev Lett. 2017 May 12;118(19):197202. doi: 10.1103/PhysRevLett.118.197202. Epub 2017 May 11.

PMID:
28548504
13.

Mechanical properties of the tumor stromal microenvironment probed in vitro and ex vivo by in situ-calibrated optical trap-based active microrheology.

Staunton JR, Vieira W, Fung KL, Lake R, Devine A, Tanner K.

Cell Mol Bioeng. 2016 Sep;9(3):398-417. Epub 2016 Aug 4.

14.

Verification of Anderson Superexchange in MnO via Magnetic Pair Distribution Function Analysis and ab initio Theory.

Frandsen BA, Brunelli M, Page K, Uemura YJ, Staunton JB, Billinge SJ.

Phys Rev Lett. 2016 May 13;116(19):197204. doi: 10.1103/PhysRevLett.116.197204. Epub 2016 May 11.

PMID:
27232042
15.
16.

In vivo tissue has non-linear rheological behavior distinct from 3D biomimetic hydrogels, as determined by AMOTIV microscopy.

Blehm BH, Devine A, Staunton JR, Tanner K.

Biomaterials. 2016 Mar;83:66-78. doi: 10.1016/j.biomaterials.2015.12.019. Epub 2015 Dec 21.

PMID:
26773661
17.

Complex Magnetism of Lanthanide Intermetallics and the Role of their Valence Electrons: Ab Initio Theory and Experiment.

Petit L, Paudyal D, Mudryk Y, Gschneidner KA Jr, Pecharsky VK, Lüders M, Szotek Z, Banerjee R, Staunton JB.

Phys Rev Lett. 2015 Nov 13;115(20):207201. doi: 10.1103/PhysRevLett.115.207201. Epub 2015 Nov 9.

PMID:
26613466
18.

Independent Control of Topography for 3D Patterning of the ECM Microenvironment.

Kim J, Staunton JR, Tanner K.

Adv Mater. 2016 Jan 6;28(1):132-7. doi: 10.1002/adma.201503950. Epub 2015 Nov 9.

19.

Assessing metal contamination from construction and demolition (C&D) waste used to infill wetlands: using Deroceras reticulatum (Mollusca: Gastropoda).

Staunton JA, Mc Donnell RJ, Gormally MJ, Williams CD, Henry T, Morrison L.

Environ Sci Process Impacts. 2014 Nov;16(11):2477-87. doi: 10.1039/c4em00300d.

PMID:
25298023
20.

Using density functional theory to describe slowly varying fluctuations at finite temperatures: local magnetic moments in Gd and the 'not so local' moments of Ni.

Staunton JB, Marmodoro A, Ernst A.

J Phys Condens Matter. 2014 Jul 9;26(27):274210. doi: 10.1088/0953-8984/26/27/274210. Epub 2014 Jun 17.

PMID:
24934388
21.

A physical sciences network characterization of non-tumorigenic and metastatic cells.

Physical Sciences - Oncology Centers Network, Agus DB, Alexander JF, Arap W, Ashili S, Aslan JE, Austin RH, Backman V, Bethel KJ, Bonneau R, Chen WC, Chen-Tanyolac C, Choi NC, Curley SA, Dallas M, Damania D, Davies PC, Decuzzi P, Dickinson L, Estevez-Salmeron L, Estrella V, Ferrari M, Fischbach C, Foo J, Fraley SI, Frantz C, Fuhrmann A, Gascard P, Gatenby RA, Geng Y, Gerecht S, Gillies RJ, Godin B, Grady WM, Greenfield A, Hemphill C, Hempstead BL, Hielscher A, Hillis WD, Holland EC, Ibrahim-Hashim A, Jacks T, Johnson RH, Joo A, Katz JE, Kelbauskas L, Kesselman C, King MR, Konstantopoulos K, Kraning-Rush CM, Kuhn P, Kung K, Kwee B, Lakins JN, Lambert G, Liao D, Licht JD, Liphardt JT, Liu L, Lloyd MC, Lyubimova A, Mallick P, Marko J, McCarty OJ, Meldrum DR, Michor F, Mumenthaler SM, Nandakumar V, O'Halloran TV, Oh S, Pasqualini R, Paszek MJ, Philips KG, Poultney CS, Rana K, Reinhart-King CA, Ros R, Semenza GL, Senechal P, Shuler ML, Srinivasan S, Staunton JR, Stypula Y, Subramanian H, Tlsty TD, Tormoen GW, Tseng Y, van Oudenaarden A, Verbridge SS, Wan JC, Weaver VM, Widom J, Will C, Wirtz D, Wojtkowiak J, Wu PH.

Sci Rep. 2013;3:1449. doi: 10.1038/srep01449.

22.

Atomic-scale engineering of magnetic anisotropy of nanostructures through interfaces and interlines.

Ouazi S, Vlaic S, Rusponi S, Moulas G, Buluschek P, Halleux K, Bornemann S, Mankovsky S, Minár J, Staunton JB, Ebert H, Brune H.

Nat Commun. 2012;3:1313. doi: 10.1038/ncomms2316.

23.

Mismatch in mechanical and adhesive properties induces pulsating cancer cell migration in epithelial monolayer.

Lee MH, Wu PH, Staunton JR, Ros R, Longmore GD, Wirtz D.

Biophys J. 2012 Jun 20;102(12):2731-41. doi: 10.1016/j.bpj.2012.05.005. Epub 2012 Jun 19.

24.

AFM stiffness nanotomography of normal, metaplastic and dysplastic human esophageal cells.

Fuhrmann A, Staunton JR, Nandakumar V, Banyai N, Davies PC, Ros R.

Phys Biol. 2011 Feb;8(1):015007. doi: 10.1088/1478-3975/8/1/015007. Epub 2011 Feb 7.

25.

Optimization of a Yellow fluorescent protein-based iodide influx high-throughput screening assay for cystic fibrosis transmembrane conductance regulator (CFTR) modulators.

Sui J, Cotard S, Andersen J, Zhu P, Staunton J, Lee M, Lin S.

Assay Drug Dev Technol. 2010 Dec;8(6):656-68. doi: 10.1089/adt.2010.0312. Epub 2010 Nov 4.

PMID:
21050066
26.

Identification of synergistic combinations of F508del cystic fibrosis transmembrane conductance regulator (CFTR) modulators.

Lin S, Sui J, Cotard S, Fung B, Andersen J, Zhu P, El Messadi N, Lehar J, Lee M, Staunton J.

Assay Drug Dev Technol. 2010 Dec;8(6):669-84. doi: 10.1089/adt.2010.0313. Epub 2010 Nov 4.

PMID:
21050065
27.

The changing patterns of covalent active site occupancy during catalysis on a modular polyketide synthase multienzyme revealed by ion-trap mass spectrometry.

Hong H, Leadlay PF, Staunton J.

FEBS J. 2009 Dec;276(23):7057-69. doi: 10.1111/j.1742-4658.2009.07418.x. Epub 2009 Oct 27.

28.

Synergistic drug combinations tend to improve therapeutically relevant selectivity.

Lehár J, Krueger AS, Avery W, Heilbut AM, Johansen LM, Price ER, Rickles RJ, Short GF 3rd, Staunton JE, Jin X, Lee MS, Zimmermann GR, Borisy AA.

Nat Biotechnol. 2009 Jul;27(7):659-66. doi: 10.1038/nbt.1549. Epub 2009 Jul 5. Erratum in: Nat Biotechnol. 2009 Sep;27(9):864.

29.

Magnetic ordering in Fe/Co sandwiches on Cu(100).

Razee SS, Staunton JB, Szunyogh L.

J Phys Condens Matter. 2009 Jul 1;21(26):265004. doi: 10.1088/0953-8984/21/26/265004. Epub 2009 Jun 11.

PMID:
21828468
30.

INT131: a selective modulator of PPAR gamma.

Motani A, Wang Z, Weiszmann J, McGee LR, Lee G, Liu Q, Staunton J, Fang Z, Fuentes H, Lindstrom M, Liu J, Biermann DH, Jaen J, Walker NP, Learned RM, Chen JL, Li Y.

J Mol Biol. 2009 Mar 13;386(5):1301-11.

PMID:
19452630
31.

Magnetism of FePt surface alloys.

Honolka J, Lee TY, Kuhnke K, Enders A, Skomski R, Bornemann S, Mankovsky S, Minár J, Staunton J, Ebert H, Hessler M, Fauth K, Schütz G, Buchsbaum A, Schmid M, Varga P, Kern K.

Phys Rev Lett. 2009 Feb 13;102(6):067207. Epub 2009 Feb 13.

PMID:
19257632
32.

A polylinker approach to reductive loop swaps in modular polyketide synthases.

Kellenberger L, Galloway IS, Sauter G, Böhm G, Hanefeld U, Cortés J, Staunton J, Leadlay PF.

Chembiochem. 2008 Nov 3;9(16):2740-9. doi: 10.1002/cbic.200800332.

PMID:
18937219
33.

Analysis of the tetronomycin gene cluster: insights into the biosynthesis of a polyether tetronate antibiotic.

Demydchuk Y, Sun Y, Hong H, Staunton J, Spencer JB, Leadlay PF.

Chembiochem. 2008 May 5;9(7):1136-45. doi: 10.1002/cbic.200700715.

PMID:
18404760
34.

Effect of pressure on magnetoelastic coupling in 3d metal alloys studied with x-ray absorption spectroscopy.

Pascarelli S, Ruffoni MP, Trapananti A, Mathon O, Aquilanti G, Ostanin S, Staunton JB, Pettifer RF.

Phys Rev Lett. 2007 Dec 7;99(23):237204. Epub 2007 Dec 6.

PMID:
18233406
35.

Lanthanide contraction and magnetism in the heavy rare earth elements.

Hughes ID, Däne M, Ernst A, Hergert W, Lüders M, Poulter J, Staunton JB, Svane A, Szotek Z, Temmerman WM.

Nature. 2007 Apr 5;446(7136):650-3.

PMID:
17410171
36.

Mn-stabilized zirconia: from imitation diamonds to a new potential high-Tc ferromagnetic spintronics material.

Ostanin S, Ernst A, Sandratskii LM, Bruno P, Däne M, Hughes ID, Staunton JB, Hergert W, Mertig I, Kudrnovský J.

Phys Rev Lett. 2007 Jan 5;98(1):016101. Epub 2007 Jan 4.

PMID:
17358488
37.

Evidence that a novel thioesterase is responsible for polyketide chain release during biosynthesis of the polyether ionophore monensin.

Harvey BM, Hong H, Jones MA, Hughes-Thomas ZA, Goss RM, Heathcote ML, Bolanos-Garcia VM, Kroutil W, Staunton J, Leadlay PF, Spencer JB.

Chembiochem. 2006 Sep;7(9):1435-42.

PMID:
16897798
38.

Evidence for the role of the monB genes in polyether ring formation during monensin biosynthesis.

Gallimore AR, Stark CB, Bhatt A, Harvey BM, Demydchuk Y, Bolanos-Garcia V, Fowler DJ, Staunton J, Leadlay PF, Spencer JB.

Chem Biol. 2006 Apr;13(4):453-60.

39.

Molecular basis of Celmer's rules: stereochemistry of catalysis by isolated ketoreductase domains from modular polyketide synthases.

Siskos AP, Baerga-Ortiz A, Bali S, Stein V, Mamdani H, Spiteller D, Popovic B, Spencer JB, Staunton J, Weissman KJ, Leadlay PF.

Chem Biol. 2005 Oct;12(10):1145-53.

40.

Accumulation of an E,E,E-triene by the monensin-producing polyketide synthase when oxidative cyclization is blocked.

Bhatt A, Stark CB, Harvey BM, Gallimore AR, Demydchuk YA, Spencer JB, Staunton J, Leadlay PF.

Angew Chem Int Ed Engl. 2005 Nov 4;44(43):7075-8. No abstract available.

PMID:
16217816
41.

Towards engineered polyketides.

Staunton J, Wilkinson B.

Expert Opin Investig Drugs. 1998 Sep;7(9):1369-87.

PMID:
15992038
42.

A new modular polyketide synthase in the erythromycin producer Saccharopolyspora erythraea.

Boakes S, Oliynyk M, Cortés J, Böhm I, Rudd BA, Revill WP, Staunton J, Leadlay PF.

J Mol Microbiol Biotechnol. 2004;8(2):73-80.

PMID:
15925898
43.

Chain initiation on type I modular polyketide synthases revealed by limited proteolysis and ion-trap mass spectrometry.

Hong H, Appleyard AN, Siskos AP, Garcia-Bernardo J, Staunton J, Leadlay PF.

FEBS J. 2005 May;272(10):2373-87.

44.

Temperature dependent magnetic anisotropy in metallic magnets from an ab initio electronic structure theory: L1(0)-ordered FePt.

Staunton JB, Ostanin S, Razee SS, Gyorffy BL, Szunyogh L, Ginatempo B, Bruno E.

Phys Rev Lett. 2004 Dec 17;93(25):257204. Epub 2004 Dec 14.

PMID:
15697934
45.

New rapamycin derivatives by precursor-directed biosynthesis.

Lowden PA, Böhm GA, Metcalfe S, Staunton J, Leadlay PF.

Chembiochem. 2004 Apr 2;5(4):535-8. No abstract available.

PMID:
15185378
46.

Isolation and characterization of pre-rapamycin, the first macrocyclic intermediate in the biosynthesis of the immunosuppressant rapamycin by S. hygroscopicus.

Gregory MA, Gaisser S, Lill RE, Hong H, Sheridan RM, Wilkinson B, Petkovic H, Weston AJ, Carletti I, Lee HL, Staunton J, Leadlay PF.

Angew Chem Int Ed Engl. 2004 May 3;43(19):2551-3. No abstract available.

PMID:
15127450
47.

Fragmentation studies on tetronasin by accurate-mass electrospray tandem mass spectrometry.

Fonseca T, Lopes NP, Gates PJ, Staunton J.

J Am Soc Mass Spectrom. 2004 Mar;15(3):325-35.

48.

Evidence for gas-phase redox chemistry inducing novel fragmentation in a complex natural product.

Lopes NP, Stark CB, Staunton J, Gates PJ.

Org Biomol Chem. 2004 Feb 7;2(3):358-63. Epub 2003 Dec 24.

PMID:
14747864
49.

Heterologous expression in Saccharopolyspora erythraea of a pentaketide synthase derived from the spinosyn polyketide synthase.

Martin CJ, Timoney MC, Sheridan RM, Kendrew SG, Wilkinson B, Staunton JC, Leadlay PF.

Org Biomol Chem. 2003 Dec 7;1(23):4144-7. Epub 2003 Oct 29.

PMID:
14685317
50.

Identification using LC-MSn of co-metabolites in the biosynthesis of the polyketide toxin mycolactone by a clinical isolate of Mycobacterium ulcerans.

Hong H, Gates PJ, Staunton J, Stinear T, Cole ST, Leadlay PF, Spencer JB.

Chem Commun (Camb). 2003 Nov 21;(22):2822-3.

PMID:
14651122

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