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Items: 1 to 50 of 152


Increased Myocyte Calcium Sensitivity in End-Stage Pediatric Dilated Cardiomyopathy.

Nakano SJ, Walker JS, Walker LA, Li X, Du Y, Miyamoto SD, Sucharov CC, Garcia AM, Mitchell MB, Ambardekar AV, Stauffer BL.

Am J Physiol Heart Circ Physiol. 2019 Oct 18. doi: 10.1152/ajpheart.00409.2019. [Epub ahead of print]


The Impact of Timing of Exercise Initiation on Weight Loss: An 18-Month Randomized Clinical Trial.

Catenacci VA, Ostendorf DM, Pan Z, Bing K, Wayland LT, Seyoum E, Stauffer BL, Phelan S, Creasy SA, Caldwell AE, Wyatt HR, Bessesen DH, Melanson EL.

Obesity (Silver Spring). 2019 Sep 29. doi: 10.1002/oby.22624. [Epub ahead of print]


VX-770-mediated potentiation of numerous human CFTR disease mutants is influenced by phosphorylation level.

Cui G, Stauffer BB, Imhoff BR, Rab A, Hong JS, Sorscher EJ, McCarty NA.

Sci Rep. 2019 Sep 17;9(1):13460. doi: 10.1038/s41598-019-49921-4.


Obesity and cardiovascular outcomes: another look at a meta-analysis of Mendelian randomization studies.

Kelley GA, Kelley KS, Stauffer BL.

J Investig Med. 2019 Jul 21. pii: jim-2019-001069. doi: 10.1136/jim-2019-001069. [Epub ahead of print]


Elamipretide Improves Mitochondrial Function in the Failing Human Heart.

Chatfield KC, Sparagna GC, Chau S, Phillips EK, Ambardekar AV, Aftab M, Mitchell MB, Sucharov CC, Miyamoto SD, Stauffer BL.

JACC Basic Transl Sci. 2019 Apr 29;4(2):147-157. doi: 10.1016/j.jacbts.2018.12.005. eCollection 2019 Apr.


Insufficient sleep is associated with a pro-atherogenic circulating microRNA signature.

Hijmans JG, Levy M, Garcia V, Lincenberg GM, Diehl KJ, Greiner JJ, Stauffer BL, DeSouza CA.

Exp Physiol. 2019 Jun;104(6):975-982. doi: 10.1113/EP087469. Epub 2019 Apr 30.


Circulating Microparticles Are Elevated in Treated HIV -1 Infection and Are Deleterious to Endothelial Cell Function.

Hijmans JG, Stockelman KA, Garcia V, Levy MV, Brewster LM, Bammert TD, Greiner JJ, Stauffer BL, Connick E, DeSouza CA.

J Am Heart Assoc. 2019 Feb 19;8(4):e011134. doi: 10.1161/JAHA.118.011134.


Phosphodiesterase-5 Is Elevated in Failing Single Ventricle Myocardium and Affects Cardiomyocyte Remodeling In Vitro.

Garcia AM, Nakano SJ, Karimpour-Fard A, Nunley K, Blain-Nelson P, Stafford NM, Stauffer BL, Sucharov CC, Miyamoto SD.

Circ Heart Fail. 2018 Sep;11(9):e004571. doi: 10.1161/CIRCHEARTFAILURE.117.004571.


Acute isoproterenol leads to age-dependent arrhythmogenesis in guinea pigs.

Woulfe KC, Wilson CE, Nau S, Chau S, Phillips EK, Zang S, Tompkins C, Sucharov CC, Miyamoto SD, Stauffer BL.

Am J Physiol Heart Circ Physiol. 2018 Oct 1;315(4):H1051-H1062. doi: 10.1152/ajpheart.00061.2018. Epub 2018 Jul 20.


Optimization of phenol-chloroform RNA extraction.

Toni LS, Garcia AM, Jeffrey DA, Jiang X, Stauffer BL, Miyamoto SD, Sucharov CC.

MethodsX. 2018 May 30;5:599-608. doi: 10.1016/j.mex.2018.05.011. eCollection 2018.


Improved Detection of Circulating miRNAs in Serum and Plasma Following Rapid Heat/Freeze Cycling.

Mariner PD, Korst A, Karimpour-Fard A, Stauffer BL, Miyamoto SD, Sucharov CC.

Microrna. 2018;7(2):138-147. doi: 10.2174/2211536607666180416152112.


Association between hypertension and circulating vascular-related microRNAs.

Hijmans JG, Diehl KJ, Bammert TD, Kavlich PJ, Lincenberg GM, Greiner JJ, Stauffer BL, DeSouza CA.

J Hum Hypertens. 2018 Jun;32(6):440-447. doi: 10.1038/s41371-018-0061-2. Epub 2018 Apr 4.


Influence of Overweight and Obesity on Circulating Inflammation-Related microRNA.

Hijmans JG, Diehl KJ, Bammert TD, Kavlich PJ, Lincenberg GM, Greiner JJ, Stauffer BL, DeSouza CA.

Microrna. 2018;7(2):148-154. doi: 10.2174/2211536607666180402120806.


Nebivolol, But Not Metoprolol, Treatment Improves Endothelial Fibrinolytic Capacity in Adults With Elevated Blood Pressure.

Stauffer BL, Dow CA, Diehl KJ, Bammert TD, Greiner JJ, DeSouza CA.

J Am Heart Assoc. 2017 Nov 9;6(11). pii: e007437. doi: 10.1161/JAHA.117.007437.


Fibrosis-Related Gene Expression in Single Ventricle Heart Disease.

Nakano SJ, Siomos AK, Garcia AM, Nguyen H, SooHoo M, Galambos C, Nunley K, Stauffer BL, Sucharov CC, Miyamoto SD.

J Pediatr. 2017 Dec;191:82-90.e2. doi: 10.1016/j.jpeds.2017.08.055. Epub 2017 Oct 16.


Insufficient sleep is associated with impaired nitric oxide-mediated endothelium-dependent vasodilation.

Bain AR, Weil BR, Diehl KJ, Greiner JJ, Stauffer BL, DeSouza CA.

Atherosclerosis. 2017 Oct;265:41-46. doi: 10.1016/j.atherosclerosis.2017.08.001. Epub 2017 Aug 18.


Pediatric dilated cardiomyopathy hearts display a unique gene expression profile.

Tatman PD, Woulfe KC, Karimpour-Fard A, Jeffrey DA, Jaggers J, Cleveland JC, Nunley K, Taylor MR, Miyamoto SD, Stauffer BL, Sucharov CC.

JCI Insight. 2017 Jul 20;2(14). pii: 94249. doi: 10.1172/jci.insight.94249. eCollection 2017 Jul 20.


Regular aerobic exercise reduces endothelin-1-mediated vasoconstrictor tone in overweight and obese adults.

Dow CA, Stauffer BL, Brunjes DL, Greiner JJ, DeSouza CA.

Exp Physiol. 2017 Sep 1;102(9):1133-1142. doi: 10.1113/EP086454. Epub 2017 Jul 16.


Bacterial Sphingomyelinase is a State-Dependent Inhibitor of the Cystic Fibrosis Transmembrane conductance Regulator (CFTR).

Stauffer BB, Cui G, Cottrill KA, Infield DT, McCarty NA.

Sci Rep. 2017 Jun 7;7(1):2931. doi: 10.1038/s41598-017-03103-2.


Influence of sex on the number of circulating endothelial microparticles and microRNA expression in middle-aged adults.

Bammert TD, Hijmans JG, Kavlich PJ, Lincenberg GM, Reiakvam WR, Fay RT, Greiner JJ, Stauffer BL, DeSouza CA.

Exp Physiol. 2017 Aug 1;102(8):894-900. doi: 10.1113/EP086359. Epub 2017 Jun 30.


Refractory Cardiogenic Shock from Right Ventricular Infarction Successfully Managed with Inhaled Epoprostenol.

Held N, Little N, Krantz MJ, Stauffer BL.

Am J Case Rep. 2017 Mar 16;18:271-275.


Exosomes from pediatric dilated cardiomyopathy patients modulate a pathological response in cardiomyocytes.

Jiang X, Sucharov J, Stauffer BL, Miyamoto SD, Sucharov CC.

Am J Physiol Heart Circ Physiol. 2017 Apr 1;312(4):H818-H826. doi: 10.1152/ajpheart.00673.2016. Epub 2017 Jan 27.


Expert consensus document: Mitochondrial function as a therapeutic target in heart failure.

Brown DA, Perry JB, Allen ME, Sabbah HN, Stauffer BL, Shaikh SR, Cleland JG, Colucci WS, Butler J, Voors AA, Anker SD, Pitt B, Pieske B, Filippatos G, Greene SJ, Gheorghiade M.

Nat Rev Cardiol. 2017 Apr;14(4):238-250. doi: 10.1038/nrcardio.2016.203. Epub 2016 Dec 22. Review.


Molecular Changes in Children with Heart Failure Undergoing Left Ventricular Assist Device Therapy.

Medina E, Sucharov CC, Nelson P, Miyamoto SD, Stauffer BL.

J Pediatr. 2017 Mar;182:184-189.e1. doi: 10.1016/j.jpeds.2016.11.011. Epub 2016 Nov 29.


Fibrosis and Fibrotic Gene Expression in Pediatric and Adult Patients With Idiopathic Dilated Cardiomyopathy.

Woulfe KC, Siomos AK, Nguyen H, SooHoo M, Galambos C, Stauffer BL, Sucharov C, Miyamoto S.

J Card Fail. 2017 Apr;23(4):314-324. doi: 10.1016/j.cardfail.2016.11.006. Epub 2016 Nov 24.


Endothelial vasodilator function in normal-weight adults with metabolic syndrome.

Dow CA, Lincenberg GM, Greiner JJ, Stauffer BL, DeSouza CA.

Appl Physiol Nutr Metab. 2016 Oct;41(10):1013-1017. Epub 2016 May 25.


Cardiac Adenylyl Cyclase and Phosphodiesterase Expression Profiles Vary by Age, Disease, and Chronic Phosphodiesterase Inhibitor Treatment.

Nakano SJ, Sucharov J, van Dusen R, Cecil M, Nunley K, Wickers S, Karimpur-Fard A, Stauffer BL, Miyamoto SD, Sucharov CC.

J Card Fail. 2017 Jan;23(1):72-80. doi: 10.1016/j.cardfail.2016.07.429. Epub 2016 Jul 15.


Potentiators exert distinct effects on human, murine, and Xenopus CFTR.

Cui G, Khazanov N, Stauffer BB, Infield DT, Imhoff BR, Senderowitz H, McCarty NA.

Am J Physiol Lung Cell Mol Physiol. 2016 Aug 1;311(2):L192-207. doi: 10.1152/ajplung.00056.2016. Epub 2016 Jun 10.


Target of rapamycin signaling mediates vacuolar fragmentation.

Stauffer B, Powers T.

Curr Genet. 2017 Feb;63(1):35-42. doi: 10.1007/s00294-016-0616-0. Epub 2016 May 27. Review.


Chronic Nebivolol Treatment Suppresses Endothelin-1-Mediated Vasoconstrictor Tone in Adults With Elevated Blood Pressure.

Diehl KJ, Stauffer BL, Dow CA, Bammert TD, Brunjes DL, Greiner JJ, DeSouza CA.

Hypertension. 2016 Jun;67(6):1196-204. doi: 10.1161/HYPERTENSIONAHA.115.06979. Epub 2016 Apr 25.


Elevations in C-reactive protein and endothelin-1 system activity in humans.

Dow CA, Templeton DL, Lincenberg GM, Greiner JJ, Stauffer BL, DeSouza CA.

Life Sci. 2016 Aug 15;159:66-70. doi: 10.1016/j.lfs.2015.12.030. Epub 2015 Dec 11.


Target of rapamycin signaling mediates vacuolar fission caused by endoplasmic reticulum stress in Saccharomyces cerevisiae.

Stauffer B, Powers T.

Mol Biol Cell. 2015 Dec 15;26(25):4618-30. doi: 10.1091/mbc.E15-06-0344. Epub 2015 Oct 14.


In Response to 'Intravenous Lipid Emulsion Given to Volunteers Does Not Affect Symptoms of Lidocaine Brain Toxicity'.

Kircher J, Stauffer B, Kessler BD, Su M.

Basic Clin Pharmacol Toxicol. 2015 Dec;117(6):361. doi: 10.1111/bcpt.12450. Epub 2015 Aug 13. No abstract available.


Junctional abnormalities in human airway epithelial cells expressing F508del CFTR.

Molina SA, Stauffer B, Moriarty HK, Kim AH, McCarty NA, Koval M.

Am J Physiol Lung Cell Mol Physiol. 2015 Sep 1;309(5):L475-87. doi: 10.1152/ajplung.00060.2015. Epub 2015 Jun 26.


Cold Regime interannual variability of primary and secondary producer community composition in the southeastern Bering Sea.

Stauffer BA, Miksis-Olds J, Goes JI.

PLoS One. 2015 Jun 25;10(6):e0131246. doi: 10.1371/journal.pone.0131246. eCollection 2015.


Influence of habitual high dietary fat intake on endothelium-dependent vasodilation.

Dow CA, Stauffer BL, Greiner JJ, DeSouza CA.

Appl Physiol Nutr Metab. 2015 Jul;40(7):711-5. doi: 10.1139/apnm-2015-0006. Epub 2015 Mar 3.


Transgenic over-expression of YY1 induces pathologic cardiac hypertrophy in a sex-specific manner.

Stauffer BL, Dockstader K, Russell G, Hijmans J, Walker L, Cecil M, Demos-Davies K, Medway A, McKinsey TA, Sucharov CC.

Biochem Biophys Res Commun. 2015 Jun 26;462(2):131-7. doi: 10.1016/j.bbrc.2015.04.106. Epub 2015 Apr 29.


Circulating microRNA as a biomarker for recovery in pediatric dilated cardiomyopathy.

Miyamoto SD, Karimpour-Fard A, Peterson V, Auerbach SR, Stenmark KR, Stauffer BL, Sucharov CC.

J Heart Lung Transplant. 2015 May;34(5):724-33. doi: 10.1016/j.healun.2015.01.979. Epub 2015 Jan 30.


Biosynthesis and transport of the lantibiotic mutacin 1140 produced by Streptococcus mutans.

Escano J, Stauffer B, Brennan J, Bullock M, Smith L.

J Bacteriol. 2015 Apr;197(7):1173-84. doi: 10.1128/JB.02531-14. Epub 2015 Jan 20.


Impaired endogenous fibrinolytic capacity in prehypertensive men.

Diehl KJ, Weil BR, Greiner JJ, Wright KP, Stauffer BL, DeSouza CA.

J Hum Hypertens. 2015 Aug;29(8):468-72. doi: 10.1038/jhh.2014.120. Epub 2015 Jan 8.


The leader peptide of mutacin 1140 has distinct structural components compared to related class I lantibiotics.

Escano J, Stauffer B, Brennan J, Bullock M, Smith L.

Microbiologyopen. 2014 Dec;3(6):961-72. doi: 10.1002/mbo3.222. Epub 2014 Nov 17.


Diet and sex modify exercise and cardiac adaptation in the mouse.

Konhilas JP, Chen H, Luczak E, McKee LA, Regan J, Watson PA, Stauffer BL, Khalpey ZI, Mckinsey TA, Horn T, LaFleur B, Leinwand LA.

Am J Physiol Heart Circ Physiol. 2015 Jan 15;308(2):H135-45. doi: 10.1152/ajpheart.00532.2014. Epub 2014 Nov 14.


Micro-RNA expression in hypoplastic left heart syndrome.

Sucharov CC, Sucharov J, Karimpour-Fard A, Nunley K, Stauffer BL, Miyamoto SD.

J Card Fail. 2015 Jan;21(1):83-8. doi: 10.1016/j.cardfail.2014.09.013. Epub 2014 Oct 5.


Age-related differences in phosphodiesterase activity and effects of chronic phosphodiesterase inhibition in idiopathic dilated cardiomyopathy.

Nakano SJ, Miyamoto SD, Movsesian M, Nelson P, Stauffer BL, Sucharov CC.

Circ Heart Fail. 2015 Jan;8(1):57-63. doi: 10.1161/CIRCHEARTFAILURE.114.001218. Epub 2014 Oct 2.



Diehl KJ, Stauffer BL, Greiner JJ, DeSouza CA.

Artery Res. 2014 Sep 1;8(3):115-118.


Influence of dietary saturated fat intake on endothelial fibrinolytic capacity in adults.

Dow CA, Stauffer BL, Greiner JJ, DeSouza CA.

Am J Cardiol. 2014 Sep 1;114(5):783-8. doi: 10.1016/j.amjcard.2014.05.066. Epub 2014 Jun 19.


New mechanistic and therapeutic targets for pediatric heart failure: report from a National Heart, Lung, and Blood Institute working group.

Burns KM, Byrne BJ, Gelb BD, Kühn B, Leinwand LA, Mital S, Pearson GD, Rodefeld M, Rossano JW, Stauffer BL, Taylor MD, Towbin JA, Redington AN.

Circulation. 2014 Jul 1;130(1):79-86. doi: 10.1161/CIRCULATIONAHA.113.007980. No abstract available.


Dysregulation of cardiolipin biosynthesis in pediatric heart failure.

Chatfield KC, Sparagna GC, Sucharov CC, Miyamoto SD, Grudis JE, Sobus RD, Hijmans J, Stauffer BL.

J Mol Cell Cardiol. 2014 Sep;74:251-9. doi: 10.1016/j.yjmcc.2014.06.002. Epub 2014 Jun 14.


Metabolic syndrome and endothelin-1 mediated vasoconstrictor tone in overweight/obese adults.

Rocha NG, Templeton DL, Greiner JJ, Stauffer BL, DeSouza CA.

Metabolism. 2014 Jul;63(7):951-6. doi: 10.1016/j.metabol.2014.04.007. Epub 2014 Apr 18.


Gene expression and β-adrenergic signaling are altered in hypoplastic left heart syndrome.

Miyamoto SD, Stauffer BL, Polk J, Medway A, Friedrich M, Haubold K, Peterson V, Nunley K, Nelson P, Sobus R, Stenmark KR, Sucharov CC.

J Heart Lung Transplant. 2014 Aug;33(8):785-93. doi: 10.1016/j.healun.2014.02.030. Epub 2014 Mar 5.

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