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Items: 36

1.

Exome sequencing-based identification of novel type 2 diabetes risk allele loci in the Qatari population.

O'Beirne SL, Salit J, Rodriguez-Flores JL, Staudt MR, Abi Khalil C, Fakhro KA, Robay A, Ramstetter MD, Malek JA, Zirie M, Jayyousi A, Badii R, Al-Nabet Al-Marri A, Bener A, Mahmoud M, Chiuchiolo MJ, Al-Shakaki A, Chidiac O, Stadler D, Mezey JG, Crystal RG.

PLoS One. 2018 Sep 13;13(9):e0199837. doi: 10.1371/journal.pone.0199837. eCollection 2018.

2.

Ontogeny and Biology of Human Small Airway Epithelial Club Cells.

Zuo WL, Shenoy SA, Li S, O'Beirne SL, Strulovici-Barel Y, Leopold PL, Wang G, Staudt MR, Walters MS, Mason C, Kaner RJ, Mezey JG, Crystal RG.

Am J Respir Crit Care Med. 2018 Dec 1;198(11):1375-1388. doi: 10.1164/rccm.201710-2107OC.

PMID:
29874100
3.

Altered lung biology of healthy never smokers following acute inhalation of E-cigarettes.

Staudt MR, Salit J, Kaner RJ, Hollmann C, Crystal RG.

Respir Res. 2018 May 14;19(1):78. doi: 10.1186/s12931-018-0778-z.

4.

Mandatory role of HMGA1 in human airway epithelial normal differentiation and post-injury regeneration.

Zhang H, Yang J, Walters MS, Staudt MR, Strulovici-Barel Y, Salit J, Mezey JG, Leopold PL, Crystal RG.

Oncotarget. 2018 Feb 16;9(18):14324-14337. doi: 10.18632/oncotarget.24511. eCollection 2018 Mar 6.

5.

Role of OSGIN1 in mediating smoking-induced autophagy in the human airway epithelium.

Wang G, Zhou H, Strulovici-Barel Y, Al-Hijji M, Ou X, Salit J, Walters MS, Staudt MR, Kaner RJ, Crystal RG.

Autophagy. 2017 Jul 3;13(7):1205-1220. doi: 10.1080/15548627.2017.1301327. Epub 2017 May 26.

6.

Smoking-Dependent Distal-to-Proximal Repatterning of the Adult Human Small Airway Epithelium.

Yang J, Zuo WL, Fukui T, Chao I, Gomi K, Lee B, Staudt MR, Kaner RJ, Strulovici-Barel Y, Salit J, Crystal RG, Shaykhiev R.

Am J Respir Crit Care Med. 2017 Aug 1;196(3):340-352. doi: 10.1164/rccm.201608-1672OC.

7.

Waterpipe smoking induces epigenetic changes in the small airway epithelium.

Walters MS, Salit J, Ju JH, Staudt MR, Kaner RJ, Rogalski AM, Sodeinde TB, Rahim R, Strulovici-Barel Y, Mezey JG, Almulla AM, Sattar H, Mahmoud M, Crystal RG.

PLoS One. 2017 Mar 8;12(3):e0171112. doi: 10.1371/journal.pone.0171112. eCollection 2017.

8.

Correction: Type 2 Diabetes Risk Allele Loci in the Qatari Population.

O'Beirne SL, Salit J, Rodriguez-Flores JL, Staudt MR, Abi Khalil C, Fakhro KA, Robay A, Ramstetter MD, Al-Azwani IK, Malek JA, Zirie M, Jayyousi A, Badii R, Al-Nabet Al-Marri A, Chiuchiolo MJ, Al-Shakaki A, Chidiac O, Gharbiah M, Bener A, Stadler D, Hackett NR, Mezey JG, Crystal RG.

PLoS One. 2016 Aug 23;11(8):e0161910. doi: 10.1371/journal.pone.0161910. eCollection 2016.

9.

Persistence of circulating endothelial microparticles in COPD despite smoking cessation.

Strulovici-Barel Y, Staudt MR, Krause A, Gordon C, Tilley AE, Harvey BG, Kaner RJ, Hollmann C, Mezey JG, Bitter H, Pillai SG, Hilton H, Wolff G, Stevenson CS, Visvanathan S, Fine JS, Crystal RG.

Thorax. 2016 Dec;71(12):1137-1144. doi: 10.1136/thoraxjnl-2015-208274. Epub 2016 Jul 26.

10.

The Qatar genome: a population-specific tool for precision medicine in the Middle East.

Fakhro KA, Staudt MR, Ramstetter MD, Robay A, Malek JA, Badii R, Al-Marri AA, Abi Khalil C, Al-Shakaki A, Chidiac O, Stadler D, Zirie M, Jayyousi A, Salit J, Mezey JG, Crystal RG, Rodriguez-Flores JL.

Hum Genome Var. 2016 Jun 30;3:16016. doi: 10.1038/hgv.2016.16. eCollection 2016.

11.

Type 2 Diabetes Risk Allele Loci in the Qatari Population.

O'Beirne SL, Salit J, Rodriguez-Flores JL, Staudt MR, Abi Khalil C, Fakhro KA, Robay A, Ramstetter MD, Al-Azwani IK, Malek JA, Zirie M, Jayyousi A, Badii R, Al-Nabet Al-Marri A, Chiuchiolo MJ, Al-Shakaki A, Chidiac O, Gharbiah M, Bener A, Stadler D, Hackett NR, Mezey JG, Crystal RG.

PLoS One. 2016 Jul 6;11(7):e0156834. doi: 10.1371/journal.pone.0156834. eCollection 2016. Erratum in: PLoS One. 2016;11(8):e0161910.

12.

JAG1-Mediated Notch Signaling Regulates Secretory Cell Differentiation of the Human Airway Epithelium.

Gomi K, Staudt MR, Salit J, Kaner RJ, Heldrich J, Rogalski AM, Arbelaez V, Crystal RG, Walters MS.

Stem Cell Rev Rep. 2016 Aug;12(4):454-63. doi: 10.1007/s12015-016-9656-6.

13.

Pulmonary Abnormalities in Young, Light-Use Waterpipe (Hookah) Smokers.

Strulovici-Barel Y, Shaykhiev R, Salit J, Deeb RS, Krause A, Kaner RJ, Vincent TL, Agosto-Perez F, Wang G, Hollmann C, Shanmugam V, Almulla AM, Sattar H, Mahmoud M, Mezey JG, Gross SS, Staudt MR, Walters MS, Crystal RG.

Am J Respir Crit Care Med. 2016 Sep 1;194(5):587-95. doi: 10.1164/rccm.201512-2470OC.

14.

POU2AF1 Functions in the Human Airway Epithelium To Regulate Expression of Host Defense Genes.

Zhou H, Brekman A, Zuo WL, Ou X, Shaykhiev R, Agosto-Perez FJ, Wang R, Walters MS, Salit J, Strulovici-Barel Y, Staudt MR, Kaner RJ, Mezey JG, Crystal RG, Wang G.

J Immunol. 2016 Apr 1;196(7):3159-67. doi: 10.4049/jimmunol.1502400. Epub 2016 Feb 29.

15.

Cigarette Smoking Induces Changes in Airway Epithelial Expression of Genes Associated with Monogenic Lung Disorders.

Tilley AE, Staudt MR, Salit J, Van de Graaf B, Strulovici-Barel Y, Kaner RJ, Vincent T, Agosto-Perez F, Mezey JG, Raby BA, Crystal RG.

Am J Respir Crit Care Med. 2016 Jan 15;193(2):215-7. doi: 10.1164/rccm.201412-2290LE. No abstract available.

16.

Serum Metabolite Biomarkers Discriminate Healthy Smokers from COPD Smokers.

Chen Q, Deeb RS, Ma Y, Staudt MR, Crystal RG, Gross SS.

PLoS One. 2015 Dec 16;10(12):e0143937. doi: 10.1371/journal.pone.0143937. eCollection 2015.

17.

Copy number variations in the genome of the Qatari population.

Fakhro KA, Yousri NA, Rodriguez-Flores JL, Robay A, Staudt MR, Agosto-Perez F, Salit J, Malek JA, Suhre K, Jayyousi A, Zirie M, Stadler D, Mezey JG, Crystal RG.

BMC Genomics. 2015 Oct 22;16:834. doi: 10.1186/s12864-015-1991-5.

18.

Persistence of smoking-induced dysregulation of miRNA expression in the small airway epithelium despite smoking cessation.

Wang G, Wang R, Strulovici-Barel Y, Salit J, Staudt MR, Ahmed J, Tilley AE, Yee-Levin J, Hollmann C, Harvey BG, Kaner RJ, Mezey JG, Sridhar S, Pillai SG, Hilton H, Wolff G, Bitter H, Visvanathan S, Fine JS, Stevenson CS, Crystal RG.

PLoS One. 2015 Apr 17;10(4):e0120824. doi: 10.1371/journal.pone.0120824. eCollection 2015.

19.

Role of SLMAP genetic variants in susceptibility of diabetes and diabetic retinopathy in Qatari population.

Upadhyay R, Robay A, Fakhro K, Abi Khalil C, Zirie M, Jayyousi A, El-Shafei M, Kiss S, D'Amico DJ, Salit J, Staudt MR, O'Beirne SL, Chen X, Tuana B, Crystal RG, Ding H.

J Transl Med. 2015 Feb 15;13:61. doi: 10.1186/s12967-015-0411-6.

20.

Airway Basal stem/progenitor cells have diminished capacity to regenerate airway epithelium in chronic obstructive pulmonary disease.

Staudt MR, Buro-Auriemma LJ, Walters MS, Salit J, Vincent T, Shaykhiev R, Mezey JG, Tilley AE, Kaner RJ, Ho MW, Crystal RG.

Am J Respir Crit Care Med. 2014 Oct 15;190(8):955-8. doi: 10.1164/rccm.201406-1167LE. No abstract available.

21.

Smoking accelerates aging of the small airway epithelium.

Walters MS, De BP, Salit J, Buro-Auriemma LJ, Wilson T, Rogalski AM, Lief L, Hackett NR, Staudt MR, Tilley AE, Harvey BG, Kaner RJ, Mezey JG, Ashbridge B, Moore MA, Crystal RG.

Respir Res. 2014 Sep 24;15:94. doi: 10.1186/s12931-014-0094-1.

22.

Smoking dysregulates the human airway basal cell transcriptome at COPD risk locus 19q13.2.

Ryan DM, Vincent TL, Salit J, Walters MS, Agosto-Perez F, Shaykhiev R, Strulovici-Barel Y, Downey RJ, Buro-Auriemma LJ, Staudt MR, Hackett NR, Mezey JG, Crystal RG.

PLoS One. 2014 Feb 3;9(2):e88051. doi: 10.1371/journal.pone.0088051. eCollection 2014.

23.

Intraflagellar transport gene expression associated with short cilia in smoking and COPD.

Hessel J, Heldrich J, Fuller J, Staudt MR, Radisch S, Hollmann C, Harvey BG, Kaner RJ, Salit J, Yee-Levin J, Sridhar S, Pillai S, Hilton H, Wolff G, Bitter H, Visvanathan S, Fine J, Stevenson CS, Crystal RG, Tilley AE.

PLoS One. 2014 Jan 20;9(1):e85453. doi: 10.1371/journal.pone.0085453. eCollection 2014.

24.

Generation of a human airway epithelium derived basal cell line with multipotent differentiation capacity.

Walters MS, Gomi K, Ashbridge B, Moore MA, Arbelaez V, Heldrich J, Ding BS, Rafii S, Staudt MR, Crystal RG.

Respir Res. 2013 Dec 3;14:135. doi: 10.1186/1465-9921-14-135.

25.

Cigarette smoking induces small airway epithelial epigenetic changes with corresponding modulation of gene expression.

Buro-Auriemma LJ, Salit J, Hackett NR, Walters MS, Strulovici-Barel Y, Staudt MR, Fuller J, Mahmoud M, Stevenson CS, Hilton H, Ho MW, Crystal RG.

Hum Mol Genet. 2013 Dec 1;22(23):4726-38. doi: 10.1093/hmg/ddt326. Epub 2013 Jul 10.

26.

Nuclear factor kappa B pathway associated biomarkers in AIDS defining malignancies.

Ramos JC, Sin SH, Staudt MR, Roy D, Vahrson W, Dezube BJ, Harrington W Jr, Dittmer DP.

Int J Cancer. 2012 Jun 1;130(11):2728-33. doi: 10.1002/ijc.26302. Epub 2011 Aug 29.

27.

Distinct p53, p53:LANA, and LANA complexes in Kaposi's Sarcoma--associated Herpesvirus Lymphomas.

Chen W, Hilton IB, Staudt MR, Burd CE, Dittmer DP.

J Virol. 2010 Apr;84(8):3898-908. doi: 10.1128/JVI.01321-09. Epub 2010 Feb 3.

28.

Model cell culture system for defining the molecular and biochemical events mediating terminal differentiation of human melanoma cells.

Staudt MR, Depass AL, Sarkar D, Fisher PB.

J Cell Physiol. 2009 Feb;218(2):304-14. doi: 10.1002/jcp.21602.

PMID:
18844238
29.

mda-7/IL-24, novel anticancer cytokine: focus on bystander antitumor, radiosensitization and antiangiogenic properties and overview of the phase I clinical experience (Review).

Lebedeva IV, Emdad L, Su ZZ, Gupta P, Sauane M, Sarkar D, Staudt MR, Liu SJ, Taher MM, Xiao R, Barral P, Lee SG, Wang D, Vozhilla N, Park ES, Chatman L, Boukerche H, Ramesh R, Inoue S, Chada S, Li R, De Pass AL, Mahasreshti PJ, Dmitriev IP, Curiel DT, Yacoub A, Grant S, Dent P, Senzer N, Nemunaitis JJ, Fisher PB.

Int J Oncol. 2007 Nov;31(5):985-1007. Review.

PMID:
17912425
30.

The Rta/Orf50 transactivator proteins of the gamma-herpesviridae.

Staudt MR, Dittmer DP.

Curr Top Microbiol Immunol. 2007;312:71-100. Review.

PMID:
17089794
31.

Rapamycin is efficacious against primary effusion lymphoma (PEL) cell lines in vivo by inhibiting autocrine signaling.

Sin SH, Roy D, Wang L, Staudt MR, Fakhari FD, Patel DD, Henry D, Harrington WJ Jr, Damania BA, Dittmer DP.

Blood. 2007 Mar 1;109(5):2165-73. Epub 2006 Nov 2.

32.
33.

The tumor microenvironment controls primary effusion lymphoma growth in vivo.

Staudt MR, Kanan Y, Jeong JH, Papin JF, Hines-Boykin R, Dittmer DP.

Cancer Res. 2004 Jul 15;64(14):4790-9.

34.

Comparison of the Rta/Orf50 transactivator proteins of gamma-2-herpesviruses.

Damania B, Jeong JH, Bowser BS, DeWire SM, Staudt MR, Dittmer DP.

J Virol. 2004 May;78(10):5491-9.

35.

Real-time Quantitative PCR Arrays for Virally-associated Cancers.

Dittmer DP, Vahrson W, Staudt MR, Papin JF, Hines-Boykin R, Fakhari FD.

Cancer Genomics Proteomics. 2004 Mar-Apr;1(2):117-124. Epub 2004 Mar 1. Review.

36.

Viral latent proteins as targets for Kaposi's sarcoma and Kaposi's sarcoma-associated herpesvirus (KSHV/HHV-8) induced lymphoma.

Staudt MR, Dittmer DP.

Curr Drug Targets Infect Disord. 2003 Jun;3(2):129-35. Review.

PMID:
12769790

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