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Items: 11


Targeting Oncogenic Signaling in Mutant FLT3 Acute Myeloid Leukemia: The Path to Least Resistance.

Staudt D, Murray HC, McLachlan T, Alvaro F, Enjeti AK, Verrills NM, Dun MD.

Int J Mol Sci. 2018 Oct 16;19(10). pii: E3198. doi: 10.3390/ijms19103198. Review.


In Vivo Visualization of Cardiomyocyte Apicobasal Polarity Reveals Epithelial to Mesenchymal-like Transition during Cardiac Trabeculation.

Jiménez-Amilburu V, Rasouli SJ, Staudt DW, Nakajima H, Chiba A, Mochizuki N, Stainier DYR.

Cell Rep. 2016 Dec 6;17(10):2687-2699. doi: 10.1016/j.celrep.2016.11.023.


CYP3A4*22 is related to increased plasma levels of 4-hydroxytamoxifen and partially compensates for reduced CYP2D6 activation of tamoxifen.

Antunes MV, de Oliveira V, Raymundo S, Staudt DE, Gössling G, Biazús JV, Cavalheiro JA, Rosa DD, Mathy G, Wallemacq P, Linden R, Schwartsmann G, Haufroid V.

Pharmacogenomics. 2015;16(6):601-17. doi: 10.2217/pgs.15.13. Epub 2015 Apr 20.


Influence of CYP2D6 and CYP3A4 Phenotypes, Drug Interactions, and Vitamin D Status on Tamoxifen Biotransformation.

Antunes MV, Timm TA, de Oliveira V, Staudt DE, Raymundo S, Gössling G, Biazús JV, Cavalheiro JA, Rosa DD, Wallemacq P, Haufroid V, Linden R, Schwartsmann G.

Ther Drug Monit. 2015 Dec;37(6):733-44. doi: 10.1097/FTD.0000000000000212.


Ultra-high performance liquid chromatography tandem mass spectrometric method for the determination of tamoxifen, N-desmethyltamoxifen, 4-hydroxytamoxifen and endoxifen in dried blood spots--development, validation and clinical application during breast cancer adjuvant therapy.

Antunes MV, Raymundo S, de Oliveira V, Staudt DE, Gössling G, Peteffi GP, Biazús JV, Cavalheiro JA, Tre-Hardy M, Capron A, Haufroid V, Wallemacq P, Schwartsmann G, Linden R.

Talanta. 2015 Jan;132:775-84. doi: 10.1016/j.talanta.2014.10.040. Epub 2014 Oct 29.


Development, validation and clinical application of a HPLC-FL method for CYP2D6 phenotyping in South Brazilian breast cancer patients.

Antunes MV, Staudt DE, Raymundo S, de Oliveira V, Gössling G, Pirolli R, Biazús JV, Cavalheiro JA, Rosa DD, Schwartsmann G, Linden R.

Clin Biochem. 2014 Aug;47(12):1084-90. doi: 10.1016/j.clinbiochem.2014.04.008. Epub 2014 Apr 18.


High-resolution imaging of cardiomyocyte behavior reveals two distinct steps in ventricular trabeculation.

Staudt DW, Liu J, Thorn KS, Stuurman N, Liebling M, Stainier DY.

Development. 2014 Feb;141(3):585-93. doi: 10.1242/dev.098632. Epub 2014 Jan 8.


Uncovering the molecular and cellular mechanisms of heart development using the zebrafish.

Staudt D, Stainier D.

Annu Rev Genet. 2012;46:397-418. doi: 10.1146/annurev-genet-110711-155646. Epub 2012 Sep 4. Review.


A dual role for ErbB2 signaling in cardiac trabeculation.

Liu J, Bressan M, Hassel D, Huisken J, Staudt D, Kikuchi K, Poss KD, Mikawa T, Stainier DY.

Development. 2010 Nov;137(22):3867-75. doi: 10.1242/dev.053736.


Competitive control of independent programs of tumor necrosis factor receptor-induced cell death by TRADD and RIP1.

Zheng L, Bidere N, Staudt D, Cubre A, Orenstein J, Chan FK, Lenardo M.

Mol Cell Biol. 2006 May;26(9):3505-13.


Histone H2AX phosphorylation is dispensable for the initial recognition of DNA breaks.

Celeste A, Fernandez-Capetillo O, Kruhlak MJ, Pilch DR, Staudt DW, Lee A, Bonner RF, Bonner WM, Nussenzweig A.

Nat Cell Biol. 2003 Jul;5(7):675-9.


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