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Items: 1 to 50 of 86

1.

Novel mouse model of indwelling pleural catheter in mice with malignant pleural effusion.

Merrick C, Sherrill T, Kanellakis NI, Asciak R, Stathopoulos GT, Maldonado F, Rahman NM, Blackwell T, Psallidas I.

ERJ Open Res. 2019 May 28;5(2). pii: 00226-2018. doi: 10.1183/23120541.00226-2018. eCollection 2019 Apr.

2.

Interleukin-1β provided by KIT-competent mast cells is required for KRAS-mutant lung adenocarcinoma.

Lilis I, Ntaliarda G, Papaleonidopoulos V, Giotopoulou GA, Oplopoiou M, Marazioti A, Spella M, Marwitz S, Goldmann T, Bravou V, Giopanou I, Stathopoulos GT.

Oncoimmunology. 2019 Apr 11;8(7):1593802. doi: 10.1080/2162402X.2019.1593802. eCollection 2019.

3.

Club cells form lung adenocarcinomas and maintain the alveoli of adult mice.

Spella M, Lilis I, Pepe MA, Chen Y, Armaka M, Lamort AS, Zazara DE, Roumelioti F, Vreka M, Kanellakis NI, Wagner DE, Giannou AD, Armenis V, Arendt KA, Klotz LV, Toumpanakis D, Karavana V, Zakynthinos SG, Giopanou I, Marazioti A, Aidinis V, Sotillo R, Stathopoulos GT.

Elife. 2019 May 29;8. pii: e45571. doi: 10.7554/eLife.45571. [Epub ahead of print]

4.

Cellular Vesicles: New insights in engineering methods, interaction with cells and potential for brain targeting.

Marazioti A, Papadia K, Kannavou M, Spella M, Basta A, de Lastic AL, Rodi M, Mouzaki A, Samiotaki M, Panayotou G, Stathopoulos GT, Antimisiaris SG.

J Pharmacol Exp Ther. 2019 May 6. pii: jpet.119.257097. doi: 10.1124/jpet.119.257097. [Epub ahead of print]

5.

Wnt1 silences chemokine genes in dendritic cells and induces adaptive immune resistance in lung adenocarcinoma.

Kerdidani D, Chouvardas P, Arjo AR, Giopanou I, Ntaliarda G, Guo YA, Tsikitis M, Kazamias G, Potaris K, Stathopoulos GT, Zakynthinos S, Kalomenidis I, Soumelis V, Kollias G, Tsoumakidou M.

Nat Commun. 2019 Mar 29;10(1):1405. doi: 10.1038/s41467-019-09370-z.

6.

Risk of lung adenocarcinoma from smoking and radiation arises in distinct molecular pathways.

Castelletti N, Kaiser JC, Simonetto C, Furukawa K, Küchenhoff H, Stathopoulos GT.

Carcinogenesis. 2019 Feb 19. pii: bgz036. doi: 10.1093/carcin/bgz036. [Epub ahead of print]

PMID:
30915466
7.

Tobacco chemical-induced mouse lung adenocarcinoma cell lines pin the prolactin orthologue proliferin as a lung tumour promoter.

Kanellakis NI, Giannou AD, Pepe MA, Αgalioti T, Zazara DE, Giopanou I, Psallidas I, Spella M, Μarazioti A, Arendt KAM, Lamort AS, Tsaniras SC, Taraviras S, Papadaki H, Lilis I, Stathopoulos GT.

Carcinogenesis. 2019 Mar 4. pii: bgz047. doi: 10.1093/carcin/bgz047. [Epub ahead of print]

PMID:
30828726
8.

Comprehensive clinical profiling of the Gauting locoregional lung adenocarcinoma donors.

Klotz LV, Courty Y, Lindner M, Petit-Courty A, Stowasser A, Koch I, Eichhorn ME, Lilis I, Morresi-Hauf A, Arendt KAM, Pepe M, Giopanou I, Ntaliarda G, Behrend SJ, Oplopoiou M, Gissot V, Guyetant S, Marchand-Adam S, Behr J, Kaiser JC, Hatz RA, Lamort AS, Stathopoulos GT.

Cancer Med. 2019 Apr;8(4):1486-1499. doi: 10.1002/cam4.2031. Epub 2019 Feb 25.

9.

Inhibition of B cell-dependent lymphoid follicle formation prevents lymphocytic bronchiolitis after lung transplantation.

Smirnova NF, Conlon TM, Morrone C, Dorfmuller P, Humbert M, Stathopoulos GT, Umkehrer S, Pfeiffer F, Yildirim AÖ, Eickelberg O.

JCI Insight. 2019 Feb 7;4(3). pii: 123971. doi: 10.1172/jci.insight.123971. [Epub ahead of print]

10.

Geminin ablation in vivo enhances tumorigenesis through increased genomic instability.

Champeris Tsaniras S, Villiou M, Giannou AD, Nikou S, Petropoulos M, Pateras IS, Tserou P, Karousi F, Lalioti ME, Gorgoulis VG, Patmanidi AL, Stathopoulos GT, Bravou V, Lygerou Z, Taraviras S.

J Pathol. 2018 Oct;246(2):134-140. doi: 10.1002/path.5128. Epub 2018 Aug 21.

PMID:
29952003
11.

Development and validation of response markers to predict survival and pleurodesis success in patients with malignant pleural effusion (PROMISE): a multicohort analysis.

Psallidas I, Kanellakis NI, Gerry S, Thézénas ML, Charles PD, Samsonova A, Schiller HB, Fischer R, Asciak R, Hallifax RJ, Mercer R, Dobson M, Dong T, Pavord ID, Collins GS, Kessler BM, Pass HI, Maskell N, Stathopoulos GT, Rahman NM.

Lancet Oncol. 2018 Jul;19(7):930-939. doi: 10.1016/S1470-2045(18)30294-8. Epub 2018 Jun 13.

PMID:
29908990
12.

RANK-c attenuates aggressive properties of ER-negative breast cancer by inhibiting NF-κB activation and EGFR signaling.

Sirinian C, Papanastasiou AD, Schizas M, Spella M, Stathopoulos GT, Repanti M, Zarkadis IK, King TA, Kalofonos HP.

Oncogene. 2018 Sep;37(37):5101-5114. doi: 10.1038/s41388-018-0324-y. Epub 2018 May 29.

PMID:
29844572
13.

The Autotaxin-Lysophosphatidic Acid Axis Promotes Lung Carcinogenesis.

Magkrioti C, Oikonomou N, Kaffe E, Mouratis MA, Xylourgidis N, Barbayianni I, Megadoukas P, Harokopos V, Valavanis C, Chun J, Kosma A, Stathopoulos GT, Bouros E, Bouros D, Syrigos K, Aidinis V.

Cancer Res. 2018 Jul 1;78(13):3634-3644. doi: 10.1158/0008-5472.CAN-17-3797. Epub 2018 May 3.

PMID:
29724718
14.

p52 expression enhances lung cancer progression.

Saxon JA, Yu H, Polosukhin VV, Stathopoulos GT, Gleaves LA, McLoed AG, Massion PP, Yull FE, Zhao Z, Blackwell TS.

Sci Rep. 2018 Apr 17;8(1):6078. doi: 10.1038/s41598-018-24488-8.

15.

IκB Kinase α Is Required for Development and Progression of KRAS-Mutant Lung Adenocarcinoma.

Vreka M, Lilis I, Papageorgopoulou M, Giotopoulou GA, Lianou M, Giopanou I, Kanellakis NI, Spella M, Agalioti T, Armenis V, Goldmann T, Marwitz S, Yull FE, Blackwell TS, Pasparakis M, Marazioti A, Stathopoulos GT.

Cancer Res. 2018 Jun 1;78(11):2939-2951. doi: 10.1158/0008-5472.CAN-17-1944. Epub 2018 Mar 27.

16.

Myeloid-derived interleukin-1β drives oncogenic KRAS-NF-κΒ addiction in malignant pleural effusion.

Marazioti A, Lilis I, Vreka M, Apostolopoulou H, Kalogeropoulou A, Giopanou I, Giotopoulou GA, Krontira AC, Iliopoulou M, Kanellakis NI, Agalioti T, Giannou AD, Jones-Paris C, Iwakura Y, Kardamakis D, Blackwell TS, Taraviras S, Spella M, Stathopoulos GT.

Nat Commun. 2018 Feb 14;9(1):672. doi: 10.1038/s41467-018-03051-z.

17.

A link between RelB expression and tumor progression in laryngeal cancer.

Giopanou I, Lilis I, Papadaki H, Papadas T, Stathopoulos GT.

Oncotarget. 2017 Dec 9;8(69):114019-114030. doi: 10.18632/oncotarget.23109. eCollection 2017 Dec 26.

18.

Cancer cells induce interleukin-22 production from memory CD4+ T cells via interleukin-1 to promote tumor growth.

Voigt C, May P, Gottschlich A, Markota A, Wenk D, Gerlach I, Voigt S, Stathopoulos GT, Arendt KAM, Heise C, Rataj F, Janssen KP, Königshoff M, Winter H, Himsl I, Thasler WE, Schnurr M, Rothenfußer S, Endres S, Kobold S.

Proc Natl Acad Sci U S A. 2017 Dec 5;114(49):12994-12999. doi: 10.1073/pnas.1705165114. Epub 2017 Nov 17.

19.

RAS oncogenes direct metastasis.

Spella M, Marazioti A, Arendt KAM, Stathopoulos GT.

Mol Cell Oncol. 2017 Jul 5;4(5):e1345711. doi: 10.1080/23723556.2017.1345711. eCollection 2017.

20.

Shared epithelial pathways to lung repair and disease.

Spella M, Lilis I, Stathopoulos GT.

Eur Respir Rev. 2017 Jun 28;26(144). pii: 170048. doi: 10.1183/16000617.0048-2017. Print 2017 Jun 30. Review.

21.

Mutant KRAS promotes malignant pleural effusion formation.

Agalioti T, Giannou AD, Krontira AC, Kanellakis NI, Kati D, Vreka M, Pepe M, Spella M, Lilis I, Zazara DE, Nikolouli E, Spiropoulou N, Papadakis A, Papadia K, Voulgaridis A, Harokopos V, Stamou P, Meiners S, Eickelberg O, Snyder LA, Antimisiaris SG, Kardamakis D, Psallidas I, Marazioti A, Stathopoulos GT.

Nat Commun. 2017 May 16;8:15205. doi: 10.1038/ncomms15205.

22.

BNN-20, a synthetic microneurotrophin, strongly protects dopaminergic neurons in the "weaver" mouse, a genetic model of dopamine-denervation, acting through the TrkB neurotrophin receptor.

Botsakis K, Mourtzi T, Panagiotakopoulou V, Vreka M, Stathopoulos GT, Pediaditakis I, Charalampopoulos I, Gravanis A, Delis F, Antoniou K, Zisimopoulos D, Georgiou CD, Panagopoulos NT, Matsokis N, Angelatou F.

Neuropharmacology. 2017 Jul 15;121:140-157. doi: 10.1016/j.neuropharm.2017.04.043. Epub 2017 Apr 28.

PMID:
28461162
23.

Lung carcinogenesis and fibrosis taken together: just coincidence?

Giopanou I, Arendt KAM, Stathopoulos GT.

Curr Opin Pulm Med. 2017 Jul;23(4):290-297. doi: 10.1097/MCP.0000000000000390. Review.

24.

NRAS destines tumor cells to the lungs.

Giannou AD, Marazioti A, Kanellakis NI, Giopanou I, Lilis I, Zazara DE, Ntaliarda G, Kati D, Armenis V, Giotopoulou GA, Krontira AC, Lianou M, Agalioti T, Vreka M, Papageorgopoulou M, Fouzas S, Kardamakis D, Psallidas I, Spella M, Stathopoulos GT.

EMBO Mol Med. 2017 May;9(5):672-686. doi: 10.15252/emmm.201606978.

25.

Multifunctional LUV liposomes decorated for BBB and amyloid targeting - B. In vivo brain targeting potential in wild-type and APP/PS1 mice.

Papadia K, Giannou AD, Markoutsa E, Bigot C, Vanhoute G, Mourtas S, Van der Linded A, Stathopoulos GT, Antimisiaris SG.

Eur J Pharm Sci. 2017 May 1;102:180-187. doi: 10.1016/j.ejps.2017.03.010. Epub 2017 Mar 8.

PMID:
28285172
26.

Tumor-derived osteopontin isoforms cooperate with TRP53 and CCL2 to promote lung metastasis.

Giopanou I, Lilis I, Papaleonidopoulos V, Agalioti T, Kanellakis NI, Spiropoulou N, Spella M, Stathopoulos GT.

Oncoimmunology. 2016 Nov 18;6(1):e1256528. doi: 10.1080/2162402X.2016.1256528. eCollection 2017.

27.

Multifunctional LUV liposomes decorated for BBB and amyloid targeting. A. In vitro proof-of-concept.

Papadia K, Markoutsa E, Mourtas S, Giannou AD, La Ferla B, Nicotra F, Salmona M, Klepetsanis P, Stathopoulos GT, Antimisiaris SG.

Eur J Pharm Sci. 2017 Apr 1;101:140-148. doi: 10.1016/j.ejps.2017.02.019. Epub 2017 Feb 11.

PMID:
28193538
28.

Translational Research in Pleural Infection and Beyond.

Lee YC, Idell S, Stathopoulos GT.

Chest. 2016 Dec;150(6):1361-1370. doi: 10.1016/j.chest.2016.07.030. Epub 2016 Aug 10. Review.

PMID:
27521736
29.

Neutrophil-Derived IL-1β Impairs the Efficacy of NF-κB Inhibitors against Lung Cancer.

McLoed AG, Sherrill TP, Cheng DS, Han W, Saxon JA, Gleaves LA, Wu P, Polosukhin VV, Karin M, Yull FE, Stathopoulos GT, Georgoulias V, Zaynagetdinov R, Blackwell TS.

Cell Rep. 2016 Jun 28;16(1):120-132. doi: 10.1016/j.celrep.2016.05.085. Epub 2016 Jun 16.

30.

Malignant pleural effusion: from bench to bedside.

Psallidas I, Kalomenidis I, Porcel JM, Robinson BW, Stathopoulos GT.

Eur Respir Rev. 2016 Jun;25(140):189-98. doi: 10.1183/16000617.0019-2016. Review. Erratum in: Eur Respir Rev. 2016 Sep;25(141):360. Eur Respir Rev. 2016 Sep;25(141):360.

31.

"Scar-cinoma": viewing the fibrotic lung mesenchymal cell in the context of cancer biology.

Horowitz JC, Osterholzer JJ, Marazioti A, Stathopoulos GT.

Eur Respir J. 2016 Jun;47(6):1842-54. doi: 10.1183/13993003.01201-2015. Epub 2016 Mar 30.

32.

Pleural involvement in lung cancer.

Agalioti T, Giannou AD, Stathopoulos GT.

J Thorac Dis. 2015 Jun;7(6):1021-30. doi: 10.3978/j.issn.2072-1439.2015.04.23. Review.

33.

Switching off malignant pleural effusion formation-fantasy or future?

Spella M, Giannou AD, Stathopoulos GT.

J Thorac Dis. 2015 Jun;7(6):1009-20. doi: 10.3978/j.issn.2072-1439.2015.05.20. Review.

34.

Comprehensive Evaluation of Nuclear Factor-κΒ Expression Patterns in Non-Small Cell Lung Cancer.

Giopanou I, Lilis I, Papaleonidopoulos V, Marazioti A, Spella M, Vreka M, Papadaki H, Stathopoulos GT.

PLoS One. 2015 Jul 6;10(7):e0132527. doi: 10.1371/journal.pone.0132527. eCollection 2015.

35.

Mast cells mediate malignant pleural effusion formation.

Giannou AD, Marazioti A, Spella M, Kanellakis NI, Apostolopoulou H, Psallidas I, Prijovich ZM, Vreka M, Zazara DE, Lilis I, Papaleonidopoulos V, Kairi CA, Patmanidi AL, Giopanou I, Spiropoulou N, Harokopos V, Aidinis V, Spyratos D, Teliousi S, Papadaki H, Taraviras S, Snyder LA, Eickelberg O, Kardamakis D, Iwakura Y, Feyerabend TB, Rodewald HR, Kalomenidis I, Blackwell TS, Agalioti T, Stathopoulos GT.

J Clin Invest. 2015 Jun;125(6):2317-34. doi: 10.1172/JCI79840. Epub 2015 Apr 27.

36.

Bosentan for patients with echocardiographic evidence of pulmonary hypertension due to long-standing rheumatic mitral stenosis.

Vlachogeorgos GS, Daskalopoulos N, Blatsiotis P, Kourbeti IS, Mantas I, Stathopoulos GT.

Hellenic J Cardiol. 2015 Jan-Feb;56(1):36-43.

37.

Interleukin-5 facilitates lung metastasis by modulating the immune microenvironment.

Zaynagetdinov R, Sherrill TP, Gleaves LA, McLoed AG, Saxon JA, Habermann AC, Connelly L, Dulek D, Peebles RS Jr, Fingleton B, Yull FE, Stathopoulos GT, Blackwell TS.

Cancer Res. 2015 Apr 15;75(8):1624-1634. doi: 10.1158/0008-5472.CAN-14-2379. Epub 2015 Feb 17.

38.

Staphylococcus aureus bio-products: new biological roles for a pleurodesis agent.

Psallidas I, Stathopoulos GT.

Respirology. 2014 Oct;19(7):948-9. doi: 10.1111/resp.12354. Epub 2014 Aug 19. No abstract available.

39.

Monoclonal antibody targeting of mononuclear cell chemokines driving malignant pleural effusion.

Marazioti A, Stathopoulos GT.

Oncoimmunology. 2014 Jun 11;3:e29195. eCollection 2014.

40.

The lymphatic system in malignant pleural effusion. Drain or immune switch?

Marazioti A, Blackwell TS, Stathopoulos GT.

Am J Respir Crit Care Med. 2014 Mar 15;189(6):626-7. doi: 10.1164/rccm.201401-0140ED. No abstract available.

PMID:
24628311
41.

Mono and dually decorated nanoliposomes for brain targeting, in vitro and in vivo studies.

Markoutsa E, Papadia K, Giannou AD, Spella M, Cagnotto A, Salmona M, Stathopoulos GT, Antimisiaris SG.

Pharm Res. 2014 May;31(5):1275-89. doi: 10.1007/s11095-013-1249-3. Epub 2013 Dec 13.

PMID:
24338512
42.

Beneficial impact of CCL2 and CCL12 neutralization on experimental malignant pleural effusion.

Marazioti A, Kairi CA, Spella M, Giannou AD, Magkouta S, Giopanou I, Papaleonidopoulos V, Kalomenidis I, Snyder LA, Kardamakis D, Stathopoulos GT.

PLoS One. 2013 Aug 14;8(8):e71207. doi: 10.1371/journal.pone.0071207. eCollection 2013.

43.

Pulmonary embolism visible on unenhanced chest computed tomography.

Stratiki M, Gianniou N, Zakynthinos SG, Stathopoulos GT.

Am J Respir Crit Care Med. 2012 Jun 1;185(11):e15. doi: 10.1164/rccm.201106-0957IM. No abstract available.

PMID:
22661531
44.

Malignant pleural effusion: tumor-host interactions unleashed.

Stathopoulos GT, Kalomenidis I.

Am J Respir Crit Care Med. 2012 Sep 15;186(6):487-92. doi: 10.1164/rccm.201203-0465PP. Epub 2012 May 31. Review.

45.

Secreted phosphoprotein-1 directly provokes vascular leakage to foster malignant pleural effusion.

Psallidas I, Stathopoulos GT, Maniatis NA, Magkouta S, Moschos C, Karabela SP, Kollintza A, Simoes DC, Kardara M, Vassiliou S, Papiris SA, Roussos C, Kalomenidis I.

Oncogene. 2013 Jan 24;32(4):528-35. doi: 10.1038/onc.2012.57. Epub 2012 Feb 27.

PMID:
22370646
46.

Opposing effects of bortezomib-induced nuclear factor-κB inhibition on chemical lung carcinogenesis.

Karabela SP, Psallidas I, Sherrill TP, Kairi CA, Zaynagetdinov R, Cheng DS, Vassiliou S, McMahon F, Gleaves LA, Han W, Stathopoulos I, Zakynthinos SG, Yull FE, Roussos C, Kalomenidis I, Blackwell TS, Stathopoulos GT.

Carcinogenesis. 2012 Apr;33(4):859-67. doi: 10.1093/carcin/bgs024. Epub 2012 Jan 27.

47.

Neutralization of tumor necrosis factor bioactivity ameliorates urethane-induced pulmonary oncogenesis in mice.

Karabela SP, Kairi CA, Magkouta S, Psallidas I, Moschos C, Stathopoulos I, Zakynthinos SG, Roussos C, Kalomenidis I, Stathopoulos GT.

Neoplasia. 2011 Dec;13(12):1143-51.

48.

A critical role for macrophages in promotion of urethane-induced lung carcinogenesis.

Zaynagetdinov R, Sherrill TP, Polosukhin VV, Han W, Ausborn JA, McLoed AG, McMahon FB, Gleaves LA, Degryse AL, Stathopoulos GT, Yull FE, Blackwell TS.

J Immunol. 2011 Dec 1;187(11):5703-11. doi: 10.4049/jimmunol.1100558. Epub 2011 Nov 2.

49.

Atypical pulmonary carcinoid tumour in a 28-year-old nonsmoker with Prader-Willi syndrome.

Nenekidis I, Stathopoulos GT, Anagnostakou V, Kokkori A, Dedeilias P, Kokotsakis J, Argiriou M, Zisis C.

Eur Respir J. 2011 Nov;38(5):1230-3. doi: 10.1183/09031936.00034711. No abstract available.

50.

Epithelial nuclear factor-κB signaling promotes lung carcinogenesis via recruitment of regulatory T lymphocytes.

Zaynagetdinov R, Stathopoulos GT, Sherrill TP, Cheng DS, McLoed AG, Ausborn JA, Polosukhin VV, Connelly L, Zhou W, Fingleton B, Peebles RS, Prince LS, Yull FE, Blackwell TS.

Oncogene. 2012 Jun 28;31(26):3164-76. doi: 10.1038/onc.2011.480. Epub 2011 Oct 17.

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