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Items: 1 to 50 of 118

1.

Vibro-Dissociation Method for Isolation of Defined Nephron Segments from Human and Rodent Kidneys.

Isaeva E, Fedoriuk M, Bohovyk R, Klemens CA, Khedr S, Golosova D, Levchenko V, El-Meanawy A, Palygin O, Staruschenko A.

Am J Physiol Renal Physiol. 2019 Oct 7. doi: 10.1152/ajprenal.00448.2019. [Epub ahead of print]

PMID:
31588797
2.

Postprandial effects on electrolyte homeostasis in the kidney.

Klemens CA, Brands MW, Staruschenko A.

Am J Physiol Renal Physiol. 2019 Sep 30. doi: 10.1152/ajprenal.00350.2019. [Epub ahead of print]

PMID:
31566434
3.

Progression of diabetic kidney disease in T2DN rats.

Palygin O, Spires D, Levchenko V, Bohovyk R, Fedoriuk M, Klemens CA, Sykes O, Bukowy JD, Cowley AW Jr, Lazar J, Ilatovskaya DV, Staruschenko A.

Am J Physiol Renal Physiol. 2019 Sep 30. doi: 10.1152/ajprenal.00246.2019. [Epub ahead of print]

PMID:
31566426
4.

Ion channels and transporters in diabetic kidney disease.

Spires D, Manis AD, Staruschenko A.

Curr Top Membr. 2019;83:353-396. doi: 10.1016/bs.ctm.2019.01.001. Epub 2019 Feb 18.

PMID:
31196609
5.

Role of TRPC6 in Progression of Diabetic Kidney Disease.

Staruschenko A, Spires D, Palygin O.

Curr Hypertens Rep. 2019 May 21;21(7):48. doi: 10.1007/s11906-019-0960-9. Review.

PMID:
31115705
6.

Increased ENaC activity during kidney preservation in Wisconsin solution.

Khedr S, Palygin O, Pavlov TS, Blass G, Levchenko V, Alsheikh A, Brands MW, El-Meanawy A, Staruschenko A.

BMC Nephrol. 2019 Apr 29;20(1):145. doi: 10.1186/s12882-019-1329-7.

7.

Postprandial Effects on ENaC-Mediated Sodium Absorption.

Blass G, Klemens CA, Brands MW, Palygin O, Staruschenko A.

Sci Rep. 2019 Mar 12;9(1):4296. doi: 10.1038/s41598-019-40639-x.

8.

Salt-deficient diet exacerbates cystogenesis in ARPKD via epithelial sodium channel (ENaC).

Ilatovskaya DV, Levchenko V, Pavlov TS, Isaeva E, Klemens CA, Johnson J, Liu P, Kriegel AJ, Staruschenko A.

EBioMedicine. 2019 Feb;40:663-674. doi: 10.1016/j.ebiom.2019.01.006. Epub 2019 Feb 8.

9.

TRPC6 in diabetic kidney disease: good guy or bad guy?

Staruschenko A.

Kidney Int. 2019 Feb;95(2):256-258. doi: 10.1016/j.kint.2018.10.027.

PMID:
30665563
10.

Genetic mutation of Kcnj16 identifies Kir5.1-containing channels as key regulators of acute and chronic pH homeostasis.

Puissant MM, Muere C, Levchenko V, Manis AD, Martino P, Forster HV, Palygin O, Staruschenko A, Hodges MR.

FASEB J. 2019 Apr;33(4):5067-5075. doi: 10.1096/fj.201802257R. Epub 2019 Jan 3.

PMID:
30605394
11.

Visualization and quantification of mitochondrial structure in the endothelium of intact arteries.

Durand MJ, Ait-Aissa K, Levchenko V, Staruschenko A, Gutterman DD, Beyer AM.

Cardiovasc Res. 2019 Aug 1;115(10):1546-1556. doi: 10.1093/cvr/cvy294.

PMID:
30476208
12.

Characterization of purinergic receptor expression in ARPKD cystic epithelia.

Palygin O, Ilatovskaya DV, Levchenko V, Klemens CA, Dissanayake L, Williams AM, Pavlov TS, Staruschenko A.

Purinergic Signal. 2018 Dec;14(4):485-497. doi: 10.1007/s11302-018-9632-5. Epub 2018 Nov 11.

13.

Endothelin receptor A and p66Shc regulate spontaneous Ca2+ oscillations in smooth muscle cells controlling renal arterial spontaneous motion.

Palygin O, Miller BS, Nishijima Y, Zhang DX, Staruschenko A, Sorokin A.

FASEB J. 2019 Feb;33(2):2636-2645. doi: 10.1096/fj.201800776RR. Epub 2018 Oct 10.

PMID:
30303741
14.

Inactivation of p66Shc Decreases Afferent Arteriolar KATP Channel Activity and Decreases Renal Damage in Diabetic Dahl SS Rats.

Miller BS, Blumenthal SR, Shalygin A, Wright KD, Staruschenko A, Imig JD, Sorokin A.

Diabetes. 2018 Nov;67(11):2206-2212. doi: 10.2337/db18-0308. Epub 2018 Aug 21.

15.

Role of the Scaffold Protein MIM in the Actin-Dependent Regulation of Epithelial Sodium Channels (ENaC).

Shuyskiy LS, Levchenko VV, Negulyaev YA, Staruschenko AV, Ilatovskaya DV.

Acta Naturae. 2018 Apr-Jun;10(2):97-103.

16.

A mutation affecting polycystin-1 mediated heterotrimeric G-protein signaling causes PKD.

Parnell SC, Magenheimer BS, Maser RL, Pavlov TS, Havens MA, Hastings ML, Jackson SF, Ward CJ, Peterson KR, Staruschenko A, Calvet JP.

Hum Mol Genet. 2018 Oct 1;27(19):3313-3324. doi: 10.1093/hmg/ddy223.

17.

Protective role of Trpc6 knockout in the progression of diabetic kidney disease.

Spires D, Ilatovskaya DV, Levchenko V, North PE, Geurts AM, Palygin O, Staruschenko A.

Am J Physiol Renal Physiol. 2018 Oct 1;315(4):F1091-F1097. doi: 10.1152/ajprenal.00155.2018. Epub 2018 Jun 20.

18.

Region-Based Convolutional Neural Nets for Localization of Glomeruli in Trichrome-Stained Whole Kidney Sections.

Bukowy JD, Dayton A, Cloutier D, Manis AD, Staruschenko A, Lombard JH, Solberg Woods LC, Beard DA, Cowley AW Jr.

J Am Soc Nephrol. 2018 Aug;29(8):2081-2088. doi: 10.1681/ASN.2017111210. Epub 2018 Jun 19.

19.

Distal tubule basolateral potassium channels: cellular and molecular mechanisms of regulation.

Palygin O, Pochynyuk O, Staruschenko A.

Curr Opin Nephrol Hypertens. 2018 Sep;27(5):373-378. doi: 10.1097/MNH.0000000000000437. Review.

20.

β1Pix exchange factor stabilizes the ubiquitin ligase Nedd4-2 and plays a critical role in ENaC regulation by AMPK in kidney epithelial cells.

Ho PY, Li H, Pavlov TS, Tuerk RD, Tabares D, Brunisholz R, Neumann D, Staruschenko A, Hallows KR.

J Biol Chem. 2018 Jul 20;293(29):11612-11624. doi: 10.1074/jbc.RA118.003082. Epub 2018 Jun 1.

21.

A NOX4/TRPC6 Pathway in Podocyte Calcium Regulation and Renal Damage in Diabetic Kidney Disease.

Ilatovskaya DV, Blass G, Palygin O, Levchenko V, Pavlov TS, Grzybowski MN, Winsor K, Shuyskiy LS, Geurts AM, Cowley AW Jr, Birnbaumer L, Staruschenko A.

J Am Soc Nephrol. 2018 Jul;29(7):1917-1927. doi: 10.1681/ASN.2018030280. Epub 2018 May 23.

22.

Beneficial Effects of High Potassium: Contribution of Renal Basolateral K+ Channels.

Staruschenko A.

Hypertension. 2018 Jun;71(6):1015-1022. doi: 10.1161/HYPERTENSIONAHA.118.10267. Epub 2018 Apr 30. Review. No abstract available.

23.

Nitric oxide production by glomerular podocytes.

Palygin O, Ilatovskaya DV, Levchenko V, Endres BT, Geurts AM, Staruschenko A.

Nitric Oxide. 2018 Jan 30;72:24-31. doi: 10.1016/j.niox.2017.11.005. Epub 2017 Nov 8.

24.

Role of adaptor protein p66Shc in renal pathologies.

Wright KD, Staruschenko A, Sorokin A.

Am J Physiol Renal Physiol. 2018 Feb 1;314(2):F143-F153. doi: 10.1152/ajprenal.00414.2017. Epub 2017 Oct 4. Review.

25.

Essential role of Kir5.1 channels in renal salt handling and blood pressure control.

Palygin O, Levchenko V, Ilatovskaya DV, Pavlov TS, Pochynyuk OM, Jacob HJ, Geurts AM, Hodges MR, Staruschenko A.

JCI Insight. 2017 Sep 21;2(18). pii: 92331. doi: 10.1172/jci.insight.92331. eCollection 2017 Sep 21.

26.

Acute In Vivo Analysis of ATP Release in Rat Kidneys in Response to Changes of Renal Perfusion Pressure.

Palygin O, Evans LC, Cowley AW Jr, Staruschenko A.

J Am Heart Assoc. 2017 Sep 12;6(9). pii: e006658. doi: 10.1161/JAHA.117.006658.

27.

Lack of Effects of Metformin and AICAR Chronic Infusion on the Development of Hypertension in Dahl Salt-Sensitive Rats.

Pavlov TS, Levchenko V, Ilatovskaya DV, Li H, Palygin O, Pastor-Soler NM, Hallows KR, Staruschenko A.

Front Physiol. 2017 Apr 20;8:227. doi: 10.3389/fphys.2017.00227. eCollection 2017.

28.

Intravital imaging of the kidney in a rat model of salt-sensitive hypertension.

Endres BT, Sandoval RM, Rhodes GJ, Campos-Bilderback SB, Kamocka MM, McDermott-Roe C, Staruschenko A, Molitoris BA, Geurts AM, Palygin O.

Am J Physiol Renal Physiol. 2017 Aug 1;313(2):F163-F173. doi: 10.1152/ajprenal.00466.2016. Epub 2017 Apr 12.

29.

Hypertension and Diabetes Mellitus: The Chicken and Egg Problem.

Staruschenko A.

Hypertension. 2017 May;69(5):787-788. doi: 10.1161/HYPERTENSIONAHA.117.08671. Epub 2017 Apr 3. No abstract available.

30.

The Role of Angiotensin II in Glomerular Volume Dynamics and Podocyte Calcium Handling.

Ilatovskaya DV, Palygin O, Levchenko V, Endres BT, Staruschenko A.

Sci Rep. 2017 Mar 22;7(1):299. doi: 10.1038/s41598-017-00406-2.

31.

The normal increase in insulin after a meal may be required to prevent postprandial renal sodium and volume losses.

Irsik DL, Blazer-Yost BL, Staruschenko A, Brands MW.

Am J Physiol Regul Integr Comp Physiol. 2017 Jun 1;312(6):R965-R972. doi: 10.1152/ajpregu.00354.2016. Epub 2017 Mar 22.

32.

Involvement of ENaC in the development of salt-sensitive hypertension.

Pavlov TS, Staruschenko A.

Am J Physiol Renal Physiol. 2017 Aug 1;313(2):F135-F140. doi: 10.1152/ajprenal.00427.2016. Epub 2016 Dec 21. Review.

33.

High salt diet and caffeine: food for thought.

Staruschenko A, Ilatovskaya DV, Pavlov TS.

J Thorac Dis. 2016 Oct;8(10):E1410-E1412. No abstract available.

34.

Protease-activated receptors in kidney disease progression.

Palygin O, Ilatovskaya DV, Staruschenko A.

Am J Physiol Renal Physiol. 2016 Dec 1;311(6):F1140-F1144. doi: 10.1152/ajprenal.00460.2016. Epub 2016 Oct 12. Review.

35.

Functional and therapeutic importance of purinergic signaling in polycystic kidney disease.

Ilatovskaya DV, Palygin O, Staruschenko A.

Am J Physiol Renal Physiol. 2016 Dec 1;311(6):F1135-F1139. doi: 10.1152/ajprenal.00406.2016. Epub 2016 Sep 21. Review.

36.

Chronic cathepsin inhibition by E-64 in Dahl salt-sensitive rats.

Blass G, Levchenko V, Ilatovskaya DV, Staruschenko A.

Physiol Rep. 2016 Sep;4(17). pii: e12950. doi: 10.14814/phy2.12950.

37.

Regulation of Polycystin-1 Function by Calmodulin Binding.

Doerr N, Wang Y, Kipp KR, Liu G, Benza JJ, Pletnev V, Pavlov TS, Staruschenko A, Mohieldin AM, Takahashi M, Nauli SM, Weimbs T.

PLoS One. 2016 Aug 25;11(8):e0161525. doi: 10.1371/journal.pone.0161525. eCollection 2016.

38.

Renal sodium transport in renin-deficient Dahl salt-sensitive rats.

Pavlov TS, Levchenko V, Ilatovskaya DV, Moreno C, Staruschenko A.

J Renin Angiotensin Aldosterone Syst. 2016 Jul 21;17(3). pii: 1470320316653858. doi: 10.1177/1470320316653858. Print 2016 Jul.

39.

The function of SH2B3 (LNK) in the kidney.

Blass G, Mattson DL, Staruschenko A.

Am J Physiol Renal Physiol. 2016 Oct 1;311(4):F682-F685. doi: 10.1152/ajprenal.00373.2016. Epub 2016 Jul 20. Review.

40.

p66Shc regulates renal vascular tone in hypertension-induced nephropathy.

Miller B, Palygin O, Rufanova VA, Chong A, Lazar J, Jacob HJ, Mattson D, Roman RJ, Williams JM, Cowley AW Jr, Geurts AM, Staruschenko A, Imig JD, Sorokin A.

J Clin Invest. 2016 Jul 1;126(7):2533-46. doi: 10.1172/JCI75079. Epub 2016 Jun 6.

41.

Role and mechanisms of regulation of the basolateral Kir 4.1/Kir 5.1K+ channels in the distal tubules.

Palygin O, Pochynyuk O, Staruschenko A.

Acta Physiol (Oxf). 2017 Jan;219(1):260-273. doi: 10.1111/apha.12703. Epub 2016 May 20. Review.

42.

Mechanosensory and ATP Release Deficits following Keratin14-Cre-Mediated TRPA1 Deletion Despite Absence of TRPA1 in Murine Keratinocytes.

Zappia KJ, Garrison SR, Palygin O, Weyer AD, Barabas ME, Lawlor MW, Staruschenko A, Stucky CL.

PLoS One. 2016 Mar 15;11(3):e0151602. doi: 10.1371/journal.pone.0151602. eCollection 2016.

43.

Two-photon imaging of endothelin-1-mediated intracellular Ca(2+) handling in smooth muscle cells of rat renal resistance arteries.

Palygin O, Miller B, Ilatovskaya DV, Sorokin A, Staruschenko A.

Life Sci. 2016 Aug 15;159:140-143. doi: 10.1016/j.lfs.2015.12.022. Epub 2015 Dec 10.

44.

Podocyte injury in diabetic nephropathy: implications of angiotensin II-dependent activation of TRPC channels.

Ilatovskaya DV, Levchenko V, Lowing A, Shuyskiy LS, Palygin O, Staruschenko A.

Sci Rep. 2015 Dec 10;5:17637. doi: 10.1038/srep17637.

45.

Evidence of the Importance of Nox4 in Production of Hypertension in Dahl Salt-Sensitive Rats.

Cowley AW Jr, Yang C, Zheleznova NN, Staruschenko A, Kurth T, Rein L, Kumar V, Sadovnikov K, Dayton A, Hoffman M, Ryan RP, Skelton MM, Salehpour F, Ranji M, Geurts A.

Hypertension. 2016 Feb;67(2):440-50. doi: 10.1161/HYPERTENSIONAHA.115.06280. Epub 2015 Dec 7.

46.

Insulin and IGF-1 activate Kir4.1/5.1 channels in cortical collecting duct principal cells to control basolateral membrane voltage.

Zaika O, Palygin O, Tomilin V, Mamenko M, Staruschenko A, Pochynyuk O.

Am J Physiol Renal Physiol. 2016 Feb 15;310(4):F311-21. doi: 10.1152/ajprenal.00436.2015. Epub 2015 Dec 2.

47.

Use of Enzymatic Biosensors to Quantify Endogenous ATP or H2O2 in the Kidney.

Palygin O, Levchenko V, Evans LC, Blass G, Cowley AW Jr, Staruschenko A.

J Vis Exp. 2015 Oct 12;(104). doi: 10.3791/53059.

48.

S&R Foundation 15th Anniversary.

Staruschenko A, Weber CR, Pochynyuk O, McCole DF.

Physiologist. 2015 Sep;58(5):241-2. No abstract available.

PMID:
26442383
49.

Implementing Patch Clamp and Live Fluorescence Microscopy to Monitor Functional Properties of Freshly Isolated PKD Epithelium.

Pavlov TS, Ilatovskaya DV, Palygin O, Levchenko V, Pochynyuk O, Staruschenko A.

J Vis Exp. 2015 Sep 1;(103). doi: 10.3791/53035.

50.

Single-channel Analysis and Calcium Imaging in the Podocytes of the Freshly Isolated Glomeruli.

Ilatovskaya DV, Palygin O, Levchenko V, Staruschenko A.

J Vis Exp. 2015 Jun 27;(100):e52850. doi: 10.3791/52850.

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