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Items: 35

1.

Genomic landscape of pediatric B-other acute lymphoblastic leukemia in a consecutive European cohort.

Zaliova M, Stuchly J, Winkowska L, Musilova A, Fiser K, Slamova M, Starkova J, Vaskova M, Hrusak O, Sramkova L, Stary J, Zuna J, Trka J.

Haematologica. 2019 Jul;104(7):1396-1406. doi: 10.3324/haematol.2018.204974. Epub 2019 Jan 10.

2.

ERG deletions in childhood acute lymphoblastic leukemia with DUX4 rearrangements are mostly polyclonal, prognostically relevant and their detection rate strongly depends on screening method sensitivity.

Zaliova M, Potuckova E, Hovorkova L, Musilova A, Winkowska L, Fiser K, Stuchly J, Mejstrikova E, Starkova J, Zuna J, Stary J, Trka J.

Haematologica. 2019 Jul;104(7):1407-1416. doi: 10.3324/haematol.2018.204487. Epub 2019 Jan 10.

3.

Assessment of the Metabolic Profile of Primary Leukemia Cells.

Hlozková K, Starková J.

J Vis Exp. 2018 Nov 21;(141). doi: 10.3791/58426.

PMID:
30531719
4.

Integrative analysis of transcriptomics and clinical data uncovers the tumor-suppressive activity of MITF in prostate cancer.

Valcarcel-Jimenez L, Macchia A, Martín-Martín N, Cortazar AR, Schaub-Clerigué A, Pujana-Vaquerizo M, Fernández-Ruiz S, Lacasa-Viscasillas I, Santos-Martin A, Loizaga-Iriarte A, Unda-Urzaiz M, Hermanova I, Astobiza I, Graupera M, Starkova J, Sutherland J, Barrio R, Aransay AM, Carracedo A, Torrano V.

Cell Death Dis. 2018 Oct 11;9(10):1041. doi: 10.1038/s41419-018-1096-6.

5.

Inhibition of the precursor and mature forms of HIV-1 protease as a tool for drug evaluation.

Humpolíčková J, Weber J, Starková J, Mašínová E, Günterová J, Flaisigová I, Konvalinka J, Majerová T.

Sci Rep. 2018 Jul 11;8(1):10438. doi: 10.1038/s41598-018-28638-w.

6.

Two novel fusion genes, AIF1L-ETV6 and ABL1-AIF1L, result together with ETV6-ABL1 from a single chromosomal rearrangement in acute lymphoblastic leukemia with prenatal origin.

Lukes J Jr, Potuckova E, Sramkova L, Stary J, Starkova J, Trka J, Votava F, Zuna J, Zaliova M.

Genes Chromosomes Cancer. 2018 Sep;57(9):471-477. doi: 10.1002/gcc.6. Epub 2018 Jul 30.

PMID:
29726059
7.

Altered Metabolism of Leukemic Cells: New Therapeutic Opportunity.

Starkova J, Hermanova I, Hlozkova K, Hararova A, Trka J.

Int Rev Cell Mol Biol. 2018;336:93-147. doi: 10.1016/bs.ircmb.2017.07.012. Epub 2017 Sep 18. Review.

PMID:
29413894
8.

A triad of NRP2, DLX and p53 proteins in lung cancer metastasis.

Drabkin HA, Starkova J, Gemmill RM.

Oncotarget. 2017 Oct 26;8(57):96464-96465. doi: 10.18632/oncotarget.22097. eCollection 2017 Nov 14. No abstract available.

9.

Low HOX gene expression in PML-RARα-positive leukemia results from suppressed histone demethylation.

Rejlova K, Musilova A, Kramarzova KS, Zaliova M, Fiser K, Alberich-Jorda M, Trka J, Starkova J.

Epigenetics. 2018;13(1):73-84. doi: 10.1080/15592294.2017.1413517. Epub 2018 Feb 7.

10.

An activating mutation of GNB1 is associated with resistance to tyrosine kinase inhibitors in ETV6-ABL1-positive leukemia.

Zimmermannova O, Doktorova E, Stuchly J, Kanderova V, Kuzilkova D, Strnad H, Starkova J, Alberich-Jorda M, Falkenburg JHF, Trka J, Petrak J, Zuna J, Zaliova M.

Oncogene. 2017 Oct 26;36(43):5985-5994. doi: 10.1038/onc.2017.210. Epub 2017 Jun 26.

11.

Distinct bilineal leukemia immunophenotypes are not genetically determined.

Kotrova M, Musilova A, Stuchly J, Fiser K, Starkova J, Mejstrikova E, Stary J, Zuna J, Hrusak O, Trka J, Zaliova M.

Blood. 2016 Nov 3;128(18):2263-2266. Epub 2016 Sep 13. No abstract available.

12.

Intragenic ERG Deletions Do Not Explain the Biology of ERG-Related Acute Lymphoblastic Leukemia.

Potuckova E, Zuna J, Hovorkova L, Starkova J, Stary J, Trka J, Zaliova M.

PLoS One. 2016 Aug 5;11(8):e0160385. doi: 10.1371/journal.pone.0160385. eCollection 2016.

13.

Human DNA-Damage-Inducible 2 Protein Is Structurally and Functionally Distinct from Its Yeast Ortholog.

Sivá M, Svoboda M, Veverka V, Trempe JF, Hofmann K, Kožíšek M, Hexnerová R, Sedlák F, Belza J, Brynda J, Šácha P, Hubálek M, Starková J, Flaisigová I, Konvalinka J, Šašková KG.

Sci Rep. 2016 Jul 27;6:30443. doi: 10.1038/srep30443.

14.

Characterization of leukemias with ETV6-ABL1 fusion.

Zaliova M, Moorman AV, Cazzaniga G, Stanulla M, Harvey RC, Roberts KG, Heatley SL, Loh ML, Konopleva M, Chen IM, Zimmermannova O, Schwab C, Smith O, Mozziconacci MJ, Chabannon C, Kim M, Frederik Falkenburg JH, Norton A, Marshall K, Haas OA, Starkova J, Stuchly J, Hunger SP, White D, Mullighan CG, Willman CL, Stary J, Trka J, Zuna J.

Haematologica. 2016 Sep;101(9):1082-93. doi: 10.3324/haematol.2016.144345. Epub 2016 May 26.

15.

Pharmacological inhibition of fatty-acid oxidation synergistically enhances the effect of l-asparaginase in childhood ALL cells.

Hermanova I, Arruabarrena-Aristorena A, Valis K, Nuskova H, Alberich-Jorda M, Fiser K, Fernandez-Ruiz S, Kavan D, Pecinova A, Niso-Santano M, Zaliova M, Novak P, Houstek J, Mracek T, Kroemer G, Carracedo A, Trka J, Starkova J.

Leukemia. 2016 Jan;30(1):209-18. doi: 10.1038/leu.2015.213. Epub 2015 Aug 4.

PMID:
26239197
16.

Design of highly potent urea-based, exosite-binding inhibitors selective for glutamate carboxypeptidase II.

Tykvart J, Schimer J, Jančařík A, Bařinková J, Navrátil V, Starková J, Šrámková K, Konvalinka J, Majer P, Šácha P.

J Med Chem. 2015 May 28;58(10):4357-63. doi: 10.1021/acs.jmedchem.5b00278. Epub 2015 May 7.

PMID:
25923815
17.

Homeobox gene expression in acute myeloid leukemia is linked to typical underlying molecular aberrations.

Skvarova Kramarzova K, Fiser K, Mejstrikova E, Rejlova K, Zaliova M, Fornerod M, Drabkin HA, van den Heuvel-Eibrink MM, Stary J, Trka J, Starkova J.

J Hematol Oncol. 2014 Dec 24;7:94. doi: 10.1186/s13045-014-0094-0.

18.

[Optimization of technological processes for the preparation of tablets with a low content of warfarin by direct compression].

Muselík J, Franc A, Starková J, Matějková Z.

Ceska Slov Farm. 2014 Oct;63(5):217-21. Czech.

PMID:
25354742
19.

Structural and biochemical characterization of the folyl-poly-γ-l-glutamate hydrolyzing activity of human glutamate carboxypeptidase II.

Navrátil M, Ptáček J, Šácha P, Starková J, Lubkowski J, Bařinka C, Konvalinka J.

FEBS J. 2014 Jul;281(14):3228-42. doi: 10.1111/febs.12857. Epub 2014 Jun 17.

20.

CD2-positive B-cell precursor acute lymphoblastic leukemia with an early switch to the monocytic lineage.

Slamova L, Starkova J, Fronkova E, Zaliova M, Reznickova L, van Delft FW, Vodickova E, Volejnikova J, Zemanova Z, Polgarova K, Cario G, Figueroa M, Kalina T, Fiser K, Bourquin JP, Bornhauser B, Dworzak M, Zuna J, Trka J, Stary J, Hrusak O, Mejstrikova E.

Leukemia. 2014 Mar;28(3):609-20. doi: 10.1038/leu.2013.354. Epub 2013 Nov 25.

PMID:
24270736
21.

Low expression of asparagine synthetase in lymphoid blasts precludes its role in sensitivity to L-asparaginase.

Hermanova I, Zaliova M, Trka J, Starkova J.

Exp Hematol. 2012 Aug;40(8):657-65. doi: 10.1016/j.exphem.2012.04.005. Epub 2012 Apr 25.

PMID:
22542578
22.

Valproic acid triggers differentiation and apoptosis in AML1/ETO-positive leukemic cells specifically.

Zapotocky M, Mejstrikova E, Smetana K, Stary J, Trka J, Starkova J.

Cancer Lett. 2012 Jun 28;319(2):144-153. doi: 10.1016/j.canlet.2011.12.041. Epub 2012 Jan 17.

PMID:
22261333
23.

Efficient and versatile one-step affinity purification of in vivo biotinylated proteins: expression, characterization and structure analysis of recombinant human glutamate carboxypeptidase II.

Tykvart J, Sácha P, Bařinka C, Knedlík T, Starková J, Lubkowski J, Konvalinka J.

Protein Expr Purif. 2012 Mar;82(1):106-15. doi: 10.1016/j.pep.2011.11.016. Epub 2011 Dec 8.

24.

Up-regulation of homeodomain genes, DLX1 and DLX2, by FLT3 signaling.

Starkova J, Gadgil S, Qiu YH, Zhang N, Hermanova I, Kornblau SM, Drabkin HA.

Haematologica. 2011 Jun;96(6):820-8. doi: 10.3324/haematol.2010.031179. Epub 2011 Feb 28.

25.

ETV6/RUNX1 (TEL/AML1) is a frequent prenatal first hit in childhood leukemia.

Zuna J, Madzo J, Krejci O, Zemanova Z, Kalinova M, Muzikova K, Zapotocky M, Starkova J, Hrusak O, Horak J, Trka J.

Blood. 2011 Jan 6;117(1):368-9; author reply 370-1. doi: 10.1182/blood-2010-09-309070. No abstract available.

26.

HOX gene expression in phenotypic and genotypic subgroups and low HOXA gene expression as an adverse prognostic factor in pediatric ALL.

Starkova J, Zamostna B, Mejstrikova E, Krejci R, Drabkin HA, Trka J.

Pediatr Blood Cancer. 2010 Dec 1;55(6):1072-82. doi: 10.1002/pbc.22749.

PMID:
20672366
27.

To the nucleolar density and size in apoptotic human leukemic myeloblasts produced in vitro by Trichostatin A.

Smetana K, Zápotocky M, Starková J, Trka J.

Eur J Histochem. 2008 Jul-Sep;52(3):143-8.

PMID:
18840553
28.

Selected metabolic parameters and the risk for uterine fibroids.

Sadlonova J, Kostal M, Smahelova A, Hendl J, Starkova J, Nachtigal P.

Int J Gynaecol Obstet. 2008 Jul;102(1):50-4. doi: 10.1016/j.ijgo.2008.01.022. Epub 2008 Mar 12.

PMID:
18336822
29.

Mean diameter of nucleolar bodies in cultured human leukemic myeloblasts is mainly related to the S and G2 phase of the cell cycle.

Smetana K, Kuzelova K, Zápotocký M, Starková J, Hrkal Z, Trka J.

Eur J Histochem. 2007 Oct-Dec;51(4):269-74.

PMID:
18162456
30.

CD44 and CD27 delineate B-precursor stages with different recombination status and with an uneven distribution in nonmalignant and malignant hematopoiesis.

Vaskova M, Fronkova E, Starkova J, Kalina T, Mejstrikova E, Hrusak O.

Tissue Antigens. 2008 Jan;71(1):57-66. Epub 2007 Nov 13.

PMID:
18005092
31.

Experimental therapy with 9-[2-(phosphonomethoxy)ethyl]-2,6-diaminopurine (PMEDAP): origin of resistance.

Zápotocký M, Hanzalová J, Starková J, Votruba I, Holý A, Otová B.

Folia Biol (Praha). 2007;53(3):79-84.

32.

Effect of histone deacetylase inhibitors on the cell nucleus and nucleolus of leukemic myeloblasts in vitro - a cytochemical study.

Smetana K, Zápotocký M, Starková J, Trka J.

Acta Histochem. 2007;109(5):413-9. Epub 2007 Jun 7.

PMID:
17559910
33.

A high-resolution structure of ligand-free human glutamate carboxypeptidase II.

Barinka C, Starkova J, Konvalinka J, Lubkowski J.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Mar 1;63(Pt 3):150-3. Epub 2007 Feb 13.

34.

The identification of (ETV6)/RUNX1-regulated genes in lymphopoiesis using histone deacetylase inhibitors in ETV6/RUNX1-positive lymphoid leukemic cells.

Starkova J, Madzo J, Cario G, Kalina T, Ford A, Zaliova M, Hrusak O, Trka J.

Clin Cancer Res. 2007 Mar 15;13(6):1726-35. Epub 2007 Feb 26.

35.

Upregulation of asparagine synthetase fails to avert cell cycle arrest induced by L-asparaginase in TEL/AML1-positive leukaemic cells.

Krejci O, Starkova J, Otova B, Madzo J, Kalinova M, Hrusak O, Trka J.

Leukemia. 2004 Mar;18(3):434-41.

PMID:
14724653

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