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Items: 23

1.

Multiplex assessment of protein variant abundance by massively parallel sequencing.

Matreyek KA, Starita LM, Stephany JJ, Martin B, Chiasson MA, Gray VE, Kircher M, Khechaduri A, Dines JN, Hause RJ, Bhatia S, Evans WE, Relling MV, Yang W, Shendure J, Fowler DM.

Nat Genet. 2018 Jun;50(6):874-882. doi: 10.1038/s41588-018-0122-z. Epub 2018 May 21.

PMID:
29785012
2.

On the design of CRISPR-based single-cell molecular screens.

Hill AJ, McFaline-Figueroa JL, Starita LM, Gasperini MJ, Matreyek KA, Packer J, Jackson D, Shendure J, Trapnell C.

Nat Methods. 2018 Apr;15(4):271-274. doi: 10.1038/nmeth.4604. Epub 2018 Feb 19.

PMID:
29457792
3.

Variant Interpretation: Functional Assays to the Rescue.

Starita LM, Ahituv N, Dunham MJ, Kitzman JO, Roth FP, Seelig G, Shendure J, Fowler DM.

Am J Hum Genet. 2017 Sep 7;101(3):315-325. doi: 10.1016/j.ajhg.2017.07.014.

4.

Bedside Back to Bench: Building Bridges between Basic and Clinical Genomic Research.

Manolio TA, Fowler DM, Starita LM, Haendel MA, MacArthur DG, Biesecker LG, Worthey E, Chisholm RL, Green ED, Jacob HJ, McLeod HL, Roden D, Rodriguez LL, Williams MS, Cooper GM, Cox NJ, Herman GE, Kingsmore S, Lo C, Lutz C, MacRae CA, Nussbaum RL, Ordovas JM, Ramos EM, Robinson PN, Rubinstein WS, Seidman C, Stranger BE, Wang H, Westerfield M, Bult C.

Cell. 2017 Mar 23;169(1):6-12. doi: 10.1016/j.cell.2017.03.005.

5.

Functional Analysis of BARD1 Missense Variants in Homology-Directed Repair of DNA Double Strand Breaks.

Lee C, Banerjee T, Gillespie J, Ceravolo A, Parvinsmith MR, Starita LM, Fields S, Toland AE, Parvin JD.

Hum Mutat. 2015 Dec;36(12):1205-14. doi: 10.1002/humu.22902. Epub 2015 Sep 22.

6.

Deep Mutational Scanning: A Highly Parallel Method to Measure the Effects of Mutation on Protein Function.

Starita LM, Fields S.

Cold Spring Harb Protoc. 2015 Aug 3;2015(8):711-4. doi: 10.1101/pdb.top077503.

PMID:
26240414
7.

Deep Mutational Scanning: Calculating Enrichment Scores for Protein Variants from DNA Sequencing Output Files.

Starita LM, Fields S.

Cold Spring Harb Protoc. 2015 Aug 3;2015(8):781-3. doi: 10.1101/pdb.prot085233.

PMID:
26240406
8.

Deep Mutational Scanning: Library Construction, Functional Selection, and High-Throughput Sequencing.

Starita LM, Fields S.

Cold Spring Harb Protoc. 2015 Aug 3;2015(8):777-80. doi: 10.1101/pdb.prot085225.

PMID:
26240405
9.

Massively Parallel Functional Analysis of BRCA1 RING Domain Variants.

Starita LM, Young DL, Islam M, Kitzman JO, Gullingsrud J, Hause RJ, Fowler DM, Parvin JD, Shendure J, Fields S.

Genetics. 2015 Jun;200(2):413-22. doi: 10.1534/genetics.115.175802. Epub 2015 Mar 30. Erratum in: Genetics. 2017 Dec;207 (4):1713.

10.

Massively parallel single-amino-acid mutagenesis.

Kitzman JO, Starita LM, Lo RS, Fields S, Shendure J.

Nat Methods. 2015 Mar;12(3):203-6, 4 p following 206. doi: 10.1038/nmeth.3223. Epub 2015 Jan 5.

11.

Activity-enhancing mutations in an E3 ubiquitin ligase identified by high-throughput mutagenesis.

Starita LM, Pruneda JN, Lo RS, Fowler DM, Kim HJ, Hiatt JB, Shendure J, Brzovic PS, Fields S, Klevit RE.

Proc Natl Acad Sci U S A. 2013 Apr 2;110(14):E1263-72. doi: 10.1073/pnas.1303309110. Epub 2013 Mar 18.

12.

Sites of ubiquitin attachment in Saccharomyces cerevisiae.

Starita LM, Lo RS, Eng JK, von Haller PD, Fields S.

Proteomics. 2012 Jan;12(2):236-40. doi: 10.1002/pmic.201100166. Epub 2011 Dec 20.

13.

Network modeling links breast cancer susceptibility and centrosome dysfunction.

Pujana MA, Han JD, Starita LM, Stevens KN, Tewari M, Ahn JS, Rennert G, Moreno V, Kirchhoff T, Gold B, Assmann V, Elshamy WM, Rual JF, Levine D, Rozek LS, Gelman RS, Gunsalus KC, Greenberg RA, Sobhian B, Bertin N, Venkatesan K, Ayivi-Guedehoussou N, Solé X, Hernández P, Lázaro C, Nathanson KL, Weber BL, Cusick ME, Hill DE, Offit K, Livingston DM, Gruber SB, Parvin JD, Vidal M.

Nat Genet. 2007 Nov;39(11):1338-49. Epub 2007 Oct 7.

PMID:
17922014
14.

Unique classes of mutations in the Saccharomyces cerevisiae G-protein translation elongation factor 1A suppress the requirement for guanine nucleotide exchange.

Ozturk SB, Vishnu MR, Olarewaju O, Starita LM, Masison DC, Kinzy TG.

Genetics. 2006 Oct;174(2):651-63. Epub 2006 Sep 1.

15.

Identification of domains of BRCA1 critical for the ubiquitin-dependent inhibition of centrosome function.

Sankaran S, Starita LM, Simons AM, Parvin JD.

Cancer Res. 2006 Apr 15;66(8):4100-7.

16.

BRCA1 DNA-binding activity is stimulated by BARD1.

Simons AM, Horwitz AA, Starita LM, Griffin K, Williams RS, Glover JN, Parvin JD.

Cancer Res. 2006 Feb 15;66(4):2012-8.

17.

Substrates of the BRCA1-dependent ubiquitin ligase.

Starita LM, Parvin JD.

Cancer Biol Ther. 2006 Feb;5(2):137-41. Epub 2006 Feb 4. Review.

PMID:
16479151
18.

Centrosomal microtubule nucleation activity is inhibited by BRCA1-dependent ubiquitination.

Sankaran S, Starita LM, Groen AC, Ko MJ, Parvin JD.

Mol Cell Biol. 2005 Oct;25(19):8656-68.

19.

BRCA1/BARD1 ubiquitinate phosphorylated RNA polymerase II.

Starita LM, Horwitz AA, Keogh MC, Ishioka C, Parvin JD, Chiba N.

J Biol Chem. 2005 Jul 1;280(26):24498-505. Epub 2005 May 10.

20.

BRCA1-dependent ubiquitination of gamma-tubulin regulates centrosome number.

Starita LM, Machida Y, Sankaran S, Elias JE, Griffin K, Schlegel BP, Gygi SP, Parvin JD.

Mol Cell Biol. 2004 Oct;24(19):8457-66.

21.

The multiple nuclear functions of BRCA1: transcription, ubiquitination and DNA repair.

Starita LM, Parvin JD.

Curr Opin Cell Biol. 2003 Jun;15(3):345-50. Review.

PMID:
12787778
23.

Mutations in elongation factor 1beta, a guanine nucleotide exchange factor, enhance translational fidelity.

Carr-Schmid A, Valente L, Loik VI, Williams T, Starita LM, Kinzy TG.

Mol Cell Biol. 1999 Aug;19(8):5257-66.

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