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Items: 1 to 50 of 97


Use of ultra-rapid whole-exome sequencing to diagnose congenital central hypoventilation syndrome.

Shanthikumar S, Kevat A, Stapleton R, Lunke S, Stark Z, Vandeleur M.

Pediatr Pulmonol. 2020 Feb 14. doi: 10.1002/ppul.24686. [Epub ahead of print] No abstract available.


Mounting Clarity on Enteral Feeding in Critically Ill Patients.

Morrissette KM, Stapleton RD.

Am J Respir Crit Care Med. 2020 Feb 3. doi: 10.1164/rccm.202001-0126ED. [Epub ahead of print] No abstract available.


Respiratory complications and 30-day unplanned hospital readmissions in patients with epilepsy.

Parikh R, Parikh R, Patel S, Desai N, Mehta T, Stapleton R.

Neurol Clin Pract. 2019 Oct;9(5):408-416. doi: 10.1212/CPJ.0000000000000672.


Metabolic support in the critically ill: a consensus of 19.

Wernerman J, Christopher KB, Annane D, Casaer MP, Coopersmith CM, Deane AM, De Waele E, Elke G, Ichai C, Karvellas CJ, McClave SA, Oudemans-van Straaten HM, Rooyackers O, Stapleton RD, Takala J, van Zanten ARH, Wischmeyer PE, Preiser JC, Vincent JL.

Crit Care. 2019 Sep 18;23(1):318. doi: 10.1186/s13054-019-2597-0. Review.


Nutrition and Exercise in Critical Illness Trial (NEXIS Trial): a protocol of a multicentred, randomised controlled trial of combined cycle ergometry and amino acid supplementation commenced early during critical illness.

Heyland DK, Day A, Clarke GJ, Hough CT, Files DC, Mourtzakis M, Deutz N, Needham DM, Stapleton R.

BMJ Open. 2019 Jul 31;9(7):e027893. doi: 10.1136/bmjopen-2018-027893.


Reply to Walter and Reyfman: Transcriptomic Analysis of Alveolar Immune Cells in Acute Respiratory Distress Syndrome: To Lump or to Split?

Morrell ED, Bhatraju PK, Mikacenic C, Radella F 2nd, Manicone AM, Stapleton RD, Wurfel MW, Gharib SA.

Am J Respir Crit Care Med. 2019 Nov 15;200(10):1321-1322. doi: 10.1164/rccm.201907-1309LE. No abstract available.


Pharmacokinetics of omega-3 fatty acids in patients with severe sepsis compared with healthy volunteers: A prospective cohort study.

Parikh R, Bates JHT, Poynter ME, Suratt BT, Parsons PE, Kien CL, Heyland DK, Crain KI, Martin J, Garudathri J, Stapleton RD.

Clin Nutr. 2019 Apr 9. pii: S0261-5614(19)30155-4. doi: 10.1016/j.clnu.2019.03.040. [Epub ahead of print]


Alveolar Macrophage Transcriptional Programs Are Associated with Outcomes in Acute Respiratory Distress Syndrome.

Morrell ED, Bhatraju PK, Mikacenic CR, Radella F 2nd, Manicone AM, Stapleton RD, Wurfel MM, Gharib SA.

Am J Respir Crit Care Med. 2019 Sep 15;200(6):732-741. doi: 10.1164/rccm.201807-1381OC.


Vitamin D Supplementation in Mechanically Ventilated Patients in the Medical Intensive Care Unit.

Leclair TR, Zakai N, Bunn JY, Gianni M, Heyland DK, Ardren SS, Stapleton RD.

JPEN J Parenter Enteral Nutr. 2019 Nov;43(8):1037-1043. doi: 10.1002/jpen.1520. Epub 2019 Feb 12.


Bronchoalveolar fluid and plasma inflammatory biomarkers in contemporary ARDS patients.

Stapleton RD, Suratt BT, Neff MJ, Wurfel MM, Ware LB, Ruzinski JT, Caldwell E, Hallstrand TS, Parsons PE.

Biomarkers. 2019 Jun;24(4):352-359. doi: 10.1080/1354750X.2019.1581840. Epub 2019 Mar 4.


Cholestenoic acid is a prognostic biomarker in acute respiratory distress syndrome.

Madenspacher JH, Stapleton RD, Suratt BT, Dixon AE, Lih FB, Lowe JM, Mould KJ, Janssen WJ, Morrell ED, Wurfel MM, Garantziotis S, Tomer KB, Fessler MB.

J Allergy Clin Immunol. 2019 Jan;143(1):440-442.e8. doi: 10.1016/j.jaci.2018.09.017. Epub 2018 Oct 5. No abstract available.


Genetic, Radiologic, and Clinical Variability in Brown-Vialetto-van Laere Syndrome.

Woodcock IR, Menezes MP, Coleman L, Yaplito-Lee J, Peters H, White SM, Stapleton R, Phelan DG, Chong B, Lunke S, Stark Z, Pitt J, Ryan MM, Robertson C, Yiu EM.

Semin Pediatr Neurol. 2018 Jul;26:2-9. doi: 10.1016/j.spen.2017.03.001. Epub 2017 Apr 5.


Should We Prescribe More Protein to Critically Ill Patients?

Heyland DK, Stapleton R, Compher C.

Nutrients. 2018 Apr 7;10(4). pii: E462. doi: 10.3390/nu10040462. Review.


Meeting the challenges of implementing rapid genomic testing in acute pediatric care.

Stark Z, Lunke S, Brett GR, Tan NB, Stapleton R, Kumble S, Yeung A, Phelan DG, Chong B, Fanjul-Fernandez M, Marum JE, Hunter M, Jarmolowicz A, Prawer Y, Riseley JR, Regan M, Elliott J, Martyn M, Best S, Tan TY, Gaff CL, White SM; Melbourne Genomics Health Alliance.

Genet Med. 2018 Dec;20(12):1554-1563. doi: 10.1038/gim.2018.37. Epub 2018 Mar 15.


Hyaluronic acid is associated with organ dysfunction in acute respiratory distress syndrome.

Esposito AJ, Bhatraju PK, Stapleton RD, Wurfel MM, Mikacenic C.

Crit Care. 2017 Dec 14;21(1):304. doi: 10.1186/s13054-017-1895-7.


Geo-economic Variations and ARDS: If a Tree Falls in a Forest….

Parsons PE, Stapleton RD.

Chest. 2017 Sep;152(3):461-462. doi: 10.1016/j.chest.2017.07.028. No abstract available.


Effect of Ganciclovir on IL-6 Levels Among Cytomegalovirus-Seropositive Adults With Critical Illness: A Randomized Clinical Trial.

Limaye AP, Stapleton RD, Peng L, Gunn SR, Kimball LE, Hyzy R, Exline MC, Files DC, Morris PE, Frankel SK, Mikkelsen ME, Hite D, Enfield KB, Steingrub J, O'Brien J, Parsons PE, Cuschieri J, Wunderink RG, Hotchkin DL, Chen YQ, Rubenfeld GD, Boeckh M.

JAMA. 2017 Aug 22;318(8):731-740. doi: 10.1001/jama.2017.10569.


Peripheral and Alveolar Cell Transcriptional Programs Are Distinct in Acute Respiratory Distress Syndrome.

Morrell ED, Radella F 2nd, Manicone AM, Mikacenic C, Stapleton RD, Gharib SA, Wurfel MM.

Am J Respir Crit Care Med. 2018 Feb 15;197(4):528-532. doi: 10.1164/rccm.201703-0614LE. No abstract available.


Haploinsufficiency for ANKRD11-flanking genes makes the difference between KBG and 16q24.3 microdeletion syndromes: 12 new cases.

Novara F, Rinaldi B, Sisodiya SM, Coppola A, Giglio S, Stanzial F, Benedicenti F, Donaldson A, Andrieux J, Stapleton R, Weber A, Reho P, van Ravenswaaij-Arts C, Kerstjens-Frederikse WS, Vermeesch JR, Devriendt K, Bacino CA, Delahaye A, Maas SM, Iolascon A, Zuffardi O.

Eur J Hum Genet. 2017 Jun;25(6):694-701. doi: 10.1038/ejhg.2017.49. Epub 2017 Apr 19.


Gender Parity in Critical Care Medicine.

Mehta S, Burns KEA, Machado FR, Fox-Robichaud AE, Cook DJ, Calfee CS, Ware LB, Burnham EL, Kissoon N, Marshall JC, Mancebo J, Finfer S, Hartog C, Reinhart K, Maitland K, Stapleton RD, Kwizera A, Amin P, Abroug F, Smith O, Laake JH, Shrestha GS, Herridge MS.

Am J Respir Crit Care Med. 2017 Aug 15;196(4):425-429. doi: 10.1164/rccm.201701-0076CP. Review.


Proceedings of the 2016 Clinical Nutrition Week Research Workshop-The Optimal Dose of Protein Provided to Critically Ill Patients.

Heyland DK, Rooyakers O, Mourtzakis M, Stapleton RD.

JPEN J Parenter Enteral Nutr. 2017 Feb;41(2):208-216. doi: 10.1177/0148607116682003. Epub 2016 Dec 22. Review.


Predicting the Mortality Benefit of CT Screening for Second Lung Cancer in a High-Risk Population.

Kinsey CM, Hamlington KL, O'Toole J, Stapleton R, Bates JH.

PLoS One. 2016 Nov 2;11(11):e0165471. doi: 10.1371/journal.pone.0165471. eCollection 2016.


Hyperleptinemia is associated with impaired pulmonary host defense.

Ubags ND, Stapleton RD, Vernooy JH, Burg E, Bement J, Hayes CM, Ventrone S, Zabeau L, Tavernier J, Poynter ME, Parsons PE, Dixon AE, Wargo MJ, Littenberg B, Wouters EF, Suratt BT.

JCI Insight. 2016 Jun 2;1(8). pii: e82101.


Patient Recruitment Rate in Multicentered Randomized Trials in Critical Care.

Nalamalapu SR, Needham DM, Stapleton RD.

Crit Care Med. 2016 Jul;44(7):e588-9. doi: 10.1097/CCM.0000000000001703. No abstract available.


ATS Core Curriculum 2016: Part II. Adult Critical Care Medicine.

McSparron JI, Hayes MM, Poston JT, Thomson CC, Fessler HE, Stapleton RD, Carlos WG, Hinkle L, Liu K, Shieh S, Ali A, Rogers A, Shah NG, Slack D, Patel B, Wolfe K, Schweickert WD, Bakhru RN, Shin S, Sell RE, Luks AM.

Ann Am Thorac Soc. 2016 May;13(5):731-40. doi: 10.1513/AnnalsATS.201601-050CME. No abstract available.


Does increased ICU strain prompt clinicians to communicate with families about end-of-life issues earlier?

Stapleton RD, Benoit DD.

Intensive Care Med. 2016 Jun;42(6):1040-2. doi: 10.1007/s00134-016-4311-x. Epub 2016 Apr 20. No abstract available.


Interleukin-17A Is Associated With Alveolar Inflammation and Poor Outcomes in Acute Respiratory Distress Syndrome.

Mikacenic C, Hansen EE, Radella F, Gharib SA, Stapleton RD, Wurfel MM.

Crit Care Med. 2016 Mar;44(3):496-502. doi: 10.1097/CCM.0000000000001409.


Combining nutrition and exercise to optimize survival and recovery from critical illness: Conceptual and methodological issues.

Heyland DK, Stapleton RD, Mourtzakis M, Hough CL, Morris P, Deutz NE, Colantuoni E, Day A, Prado CM, Needham DM.

Clin Nutr. 2016 Oct;35(5):1196-206. doi: 10.1016/j.clnu.2015.07.003. Epub 2015 Jul 16.


Obesity and nutrition in acute respiratory distress syndrome.

Stapleton RD, Suratt BT.

Clin Chest Med. 2014 Dec;35(4):655-71. doi: 10.1016/j.ccm.2014.08.005. Epub 2014 Sep 24. Review.


Physiological and management implications of obesity in critical illness.

Shashaty MG, Stapleton RD.

Ann Am Thorac Soc. 2014 Oct;11(8):1286-97. doi: 10.1513/AnnalsATS.201404-159FR. Review.


Long-term outcomes after in-hospital CPR in older adults with chronic illness.

Stapleton RD, Ehlenbach WJ, Deyo RA, Curtis JR.

Chest. 2014 Nov;146(5):1214-1225. doi: 10.1378/chest.13-2110.


Telemedicine as a tool to provide family conferences and palliative care consultations in critically ill patients at rural health care institutions: a pilot study.

Menon PR, Stapleton RD, McVeigh U, Rabinowitz T.

Am J Hosp Palliat Care. 2015 Jun;32(4):448-53. doi: 10.1177/1049909114537110. Epub 2014 May 28.


Cardiopulmonary resuscitation among mechanically ventilated patients.

Al-Alwan A, Ehlenbach WJ, Menon PR, Young MP, Stapleton RD.

Intensive Care Med. 2014 Apr;40(4):556-63. doi: 10.1007/s00134-014-3247-2. Epub 2014 Feb 26.


Multiple in-hospital resuscitation efforts in the elderly.

Menon PR, Ehlenbach WJ, Ford DW, Stapleton RD.

Crit Care Med. 2014 Jan;42(1):108-17. doi: 10.1097/CCM.0b013e31829eb937.


Alternative lipid emulsions in the critically ill: a systematic review of the evidence.

Manzanares W, Dhaliwal R, Jurewitsch B, Stapleton RD, Jeejeebhoy KN, Heyland DK.

Intensive Care Med. 2013 Oct;39(10):1683-94. doi: 10.1007/s00134-013-2999-4. Epub 2013 Jun 29. Review.


Parenteral fish oil lipid emulsions in the critically ill: a systematic review and meta-analysis.

Manzanares W, Dhaliwal R, Jurewitsch B, Stapleton RD, Jeejeebhoy KN, Heyland DK.

JPEN J Parenter Enteral Nutr. 2014 Jan;38(1):20-8. doi: 10.1177/0148607113486006. Epub 2013 Apr 22. Review.


Still a man's world, but why?

Weinacker A, Stapleton RD.

Crit Care. 2013 Jan 29;17(1):113. doi: 10.1186/cc11915.


The ethical and economic impact of defaults.

Siegel MD, Stapleton R, Wunsch H.

Semin Respir Crit Care Med. 2012 Aug;33(4):382-92. doi: 10.1055/s-0032-1322402. Epub 2012 Aug 8. Review.


A comparison of predictive equations of energy expenditure and measured energy expenditure in critically ill patients.

Kross EK, Sena M, Schmidt K, Stapleton RD.

J Crit Care. 2012 Jun;27(3):321.e5-12. doi: 10.1016/j.jcrc.2011.07.084. Epub 2012 Mar 14.


Not all critically ill obese patients are the same: the influence of prior comorbidities.

Rahman A, Stapleton RD, Heyland DK.

ISRN Obes. 2012 Nov 4;2012:743978. doi: 10.5402/2012/743978. eCollection 2012.


Extreme obesity and outcomes in critically ill patients.

Martino JL, Stapleton RD, Wang M, Day AG, Cahill NE, Dixon AE, Suratt BT, Heyland DK.

Chest. 2011 Nov;140(5):1198-1206. doi: 10.1378/chest.10-3023. Epub 2011 Aug 4.


A phase II randomized placebo-controlled trial of omega-3 fatty acids for the treatment of acute lung injury.

Stapleton RD, Martin TR, Weiss NS, Crowley JJ, Gundel SJ, Nathens AB, Akhtar SR, Ruzinski JT, Caldwell E, Curtis JR, Heyland DK, Watkins TR, Parsons PE, Martin JM, Wurfel MM, Hallstrand TS, Sims KA, Neff MJ.

Crit Care Med. 2011 Jul;39(7):1655-62. doi: 10.1097/CCM.0b013e318218669d.


Anxiety and depression among opiate users who misuse substances during treatment.

Stapleton R, Comiskey C.

Ir J Psychol Med. 2011 Mar;28(1):6-12. doi: 10.1017/S0790966700011848.


Omega-3 fatty acids in critical illness.

Martin JM, Stapleton RD.

Nutr Rev. 2010 Sep;68(9):531-41. doi: 10.1111/j.1753-4887.2010.00313.x. Review.


Fish oil in critical illness: mechanisms and clinical applications.

Stapleton RD, Martin JM, Mayer K.

Crit Care Clin. 2010 Jul;26(3):501-14, ix. doi: 10.1016/j.ccc.2010.04.009. Review.


The association between BMI and plasma cytokine levels in patients with acute lung injury.

Stapleton RD, Dixon AE, Parsons PE, Ware LB, Suratt BT; NHLBI Acute Respiratory Distress Syndrome Network.

Chest. 2010 Sep;138(3):568-77. doi: 10.1378/chest.10-0014. Epub 2010 Apr 30.


Longitudinal outcomes for treated opiate use and the use of ancillary medical and social services.

Comiskey CM, Stapleton R.

Subst Use Misuse. 2010 Mar;45(4):628-41. doi: 10.3109/10826080903452504.


Inter- and intra-observer variability associated with the use of the Mirels' scoring system for metastatic bone lesions.

Mac Niocaill RF, Quinlan JF, Stapleton RD, Hurson B, Dudeney S, O'Toole GC.

Int Orthop. 2011 Jan;35(1):83-6. doi: 10.1007/s00264-009-0941-8. Epub 2010 Jan 19.


Alcohol usage and associated treatment outcomes for opiate users entering treatment in Ireland.

Stapleton RD, Comiskey CM.

Drug Alcohol Depend. 2010 Feb 1;107(1):56-61. doi: 10.1016/j.drugalcdep.2009.09.007. Epub 2009 Oct 12.


Serum albumin and total lymphocyte count as predictors of outcome in hip fractures.

O'Daly BJ, Walsh JC, Quinlan JF, Falk GA, Stapleton R, Quinlan WR, O'Rourke SK.

Clin Nutr. 2010 Feb;29(1):89-93. doi: 10.1016/j.clnu.2009.07.007. Epub 2009 Aug 11.


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