Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 118

1.

Rapid generation of purified human RPE from pluripotent stem cells using 2D cultures and lipoprotein uptake-based sorting.

Michelet F, Balasankar A, Teo N, Stanton LW, Singhal S.

Stem Cell Res Ther. 2020 Feb 3;11(1):47. doi: 10.1186/s13287-020-1568-3.

2.

A balanced translocation in Kallmann Syndrome implicates a long noncoding RNA, RMST, as a GnRH neuronal regulator.

Stamou M, Ng SY, Brand H, Wang H, Plummer L, Best L, Havlicek S, Hibberd M, Khor CC, Gusella J, Balasubramanian R, Talkowski M, Stanton LW, Crowley WF.

J Clin Endocrinol Metab. 2019 Oct 19. pii: dgz011. doi: 10.1210/clinem/dgz011. [Epub ahead of print]

PMID:
31628846
3.

Phenotypic and molecular features underlying neurodegeneration of motor neurons derived from spinal and bulbar muscular atrophy patients.

Sheila M, Narayanan G, Ma S, Tam WL, Chai J, Stanton LW.

Neurobiol Dis. 2019 Apr;124:1-13. doi: 10.1016/j.nbd.2018.10.019. Epub 2018 Nov 1.

PMID:
30391288
4.

APP upregulation contributes to retinal ganglion cell degeneration via JNK3.

Liu C, Zhang CW, Zhou Y, Wong WQ, Lee LC, Ong WY, Yoon SO, Hong W, Fu XY, Soong TW, Koo EH, Stanton LW, Lim KL, Xiao ZC, Dawe GS.

Cell Death Differ. 2018 Mar;25(4):663-678. doi: 10.1038/s41418-017-0005-3. Epub 2017 Dec 13.

5.

Single-cell gene expression analysis reveals regulators of distinct cell subpopulations among developing human neurons.

Wang J, Jenjaroenpun P, Bhinge A, Angarica VE, Del Sol A, Nookaew I, Kuznetsov VA, Stanton LW.

Genome Res. 2017 Nov;27(11):1783-1794. doi: 10.1101/gr.223313.117. Epub 2017 Oct 13.

6.

Phosphorylation of amyloid precursor protein by mutant LRRK2 promotes AICD activity and neurotoxicity in Parkinson's disease.

Chen ZC, Zhang W, Chua LL, Chai C, Li R, Lin L, Cao Z, Angeles DC, Stanton LW, Peng JH, Zhou ZD, Lim KL, Zeng L, Tan EK.

Sci Signal. 2017 Jul 18;10(488). pii: eaam6790. doi: 10.1126/scisignal.aam6790.

PMID:
28720718
7.

Long-Term Culture of Self-renewing Pancreatic Progenitors Derived from Human Pluripotent Stem Cells.

Trott J, Tan EK, Ong S, Titmarsh DM, Denil SLIJ, Giam M, Wong CK, Wang J, Shboul M, Eio M, Cooper-White J, Cool SM, Rancati G, Stanton LW, Reversade B, Dunn NR.

Stem Cell Reports. 2017 Jun 6;8(6):1675-1688. doi: 10.1016/j.stemcr.2017.05.019.

8.

Cyclin-Dependent Kinase-Dependent Phosphorylation of Sox2 at Serine 39 Regulates Neurogenesis.

Lim S, Bhinge A, Bragado Alonso S, Aksoy I, Aprea J, Cheok CF, Calegari F, Stanton LW, Kaldis P.

Mol Cell Biol. 2017 Jul 28;37(16). pii: e00201-17. doi: 10.1128/MCB.00201-17. Print 2017 Aug 15.

9.

Transcriptome analysis for the identification of cellular markers related to trabecular meshwork differentiation.

Sathiyanathan P, Tay CY, Stanton LW.

BMC Genomics. 2017 May 17;18(1):383. doi: 10.1186/s12864-017-3758-7.

10.

Generation of sibling-matched induced pluripotent stem cell lines from spinal and bulbar muscular atrophy patients.

Narayanan G, Sheila M, Chai J, Stanton LW.

Stem Cell Res. 2017 Apr;20:30-33. doi: 10.1016/j.scr.2017.02.005. Epub 2017 Feb 16.

11.

Genetic Correction of SOD1 Mutant iPSCs Reveals ERK and JNK Activated AP1 as a Driver of Neurodegeneration in Amyotrophic Lateral Sclerosis.

Bhinge A, Namboori SC, Zhang X, VanDongen AMJ, Stanton LW.

Stem Cell Reports. 2017 Apr 11;8(4):856-869. doi: 10.1016/j.stemcr.2017.02.019. Epub 2017 Mar 30.

12.

Personalized genome sequencing coupled with iPSC technology identifies GTDC1 as a gene involved in neurodevelopmental disorders.

Aksoy I, Utami KH, Winata CL, Hillmer AM, Rouam SL, Briault S, Davila S, Stanton LW, Cacheux V.

Hum Mol Genet. 2017 Jan 15;26(2):367-382. doi: 10.1093/hmg/ddw393.

PMID:
28365779
13.

Re-engineered RNA-Guided FokI-Nucleases for Improved Genome Editing in Human Cells.

Havlicek S, Shen Y, Alpagu Y, Bruntraeger MB, Zufir NB, Phuah ZY, Fu Z, Dunn NR, Stanton LW.

Mol Ther. 2017 Feb 1;25(2):342-355. doi: 10.1016/j.ymthe.2016.11.007.

14.

Molecular Features Underlying Neurodegeneration Identified through In Vitro Modeling of Genetically Diverse Parkinson's Disease Patients.

Lin L, Göke J, Cukuroglu E, Dranias MR, VanDongen AM, Stanton LW.

Cell Rep. 2016 Jun 14;15(11):2411-26. doi: 10.1016/j.celrep.2016.05.022. Epub 2016 Jun 2.

15.

A pharmacogenomic profile of human neural progenitors undergoing differentiation in the presence of the traditional Chinese medicine NeuroAiD.

Chan HY, Stanton LW.

Pharmacogenomics J. 2016 Oct;16(5):461-71. doi: 10.1038/tpj.2016.21. Epub 2016 Apr 5.

PMID:
27044682
16.

A Role for RE-1-Silencing Transcription Factor in Embryonic Stem Cells Cardiac Lineage Specification.

Aksoy I, Marcy G, Chen J, Divakar U, Kumar V, John-Sanchez D, Rahmani M, Buckley NJ, Stanton LW.

Stem Cells. 2016 Apr;34(4):860-72. doi: 10.1002/stem.2304. Epub 2016 Feb 22.

17.

Chromatin and RNA Maps Reveal Regulatory Long Noncoding RNAs in Mouse.

Bogu GK, Vizán P, Stanton LW, Beato M, Di Croce L, Marti-Renom MA.

Mol Cell Biol. 2015 Dec 28;36(5):809-19. doi: 10.1128/MCB.00955-15.

18.

Global mapping of the regulatory interactions of histone residues.

Jung I, Seo J, Lee HS, Stanton LW, Kim D, Choi JK.

FEBS Lett. 2015 Dec 21;589(24 Pt B):4061-70. doi: 10.1016/j.febslet.2015.11.016. Epub 2015 Nov 19.

19.

MiR-375 is Essential for Human Spinal Motor Neuron Development and May Be Involved in Motor Neuron Degeneration.

Bhinge A, Namboori SC, Bithell A, Soldati C, Buckley NJ, Stanton LW.

Stem Cells. 2016 Jan;34(1):124-34. doi: 10.1002/stem.2233. Epub 2015 Nov 20.

20.

The Neurogenic Potential of Astrocytes Is Regulated by Inflammatory Signals.

Michelucci A, Bithell A, Burney MJ, Johnston CE, Wong KY, Teng SW, Desai J, Gumbleton N, Anderson G, Stanton LW, Williams BP, Buckley NJ.

Mol Neurobiol. 2016 Aug;53(6):3724-3739. doi: 10.1007/s12035-015-9296-x. Epub 2015 Jul 4.

21.

Reinforcement of STAT3 activity reprogrammes human embryonic stem cells to naive-like pluripotency.

Chen H, Aksoy I, Gonnot F, Osteil P, Aubry M, Hamela C, Rognard C, Hochard A, Voisin S, Fontaine E, Mure M, Afanassieff M, Cleroux E, Guibert S, Chen J, Vallot C, Acloque H, Genthon C, Donnadieu C, De Vos J, Sanlaville D, Guérin JF, Weber M, Stanton LW, Rougeulle C, Pain B, Bourillot PY, Savatier P.

Nat Commun. 2015 May 13;6:7095. doi: 10.1038/ncomms8095.

22.

PDX1 binds and represses hepatic genes to ensure robust pancreatic commitment in differentiating human embryonic stem cells.

Teo AK, Tsuneyoshi N, Hoon S, Tan EK, Stanton LW, Wright CV, Dunn NR.

Stem Cell Reports. 2015 Apr 14;4(4):578-90. doi: 10.1016/j.stemcr.2015.02.015. Epub 2015 Apr 2.

23.

Pluripotency Activity of Nanog Requires Biochemical Stabilization by Variant Histone Protein H2A.Z.

Wang J, Qiao M, He Q, Shi R, Loh SJ, Stanton LW, Wu M.

Stem Cells. 2015 Jul;33(7):2126-34. doi: 10.1002/stem.2011. Epub 2015 May 21.

24.

Establishing criteria for human mesenchymal stem cell potency.

Samsonraj RM, Rai B, Sathiyanathan P, Puan KJ, Rötzschke O, Hui JH, Raghunath M, Stanton LW, Nurcombe V, Cool SM.

Stem Cells. 2015 Jun;33(6):1878-91. doi: 10.1002/stem.1982.

25.

APP intracellular domain acts as a transcriptional regulator of miR-663 suppressing neuronal differentiation.

Shu R, Wong W, Ma QH, Yang ZZ, Zhu H, Liu FJ, Wang P, Ma J, Yan S, Polo JM, Bernard CC, Stanton LW, Dawe GS, Xiao ZC.

Cell Death Dis. 2015 Feb 19;6:e1651. doi: 10.1038/cddis.2015.10.

26.

RE1 silencing transcription factor/neuron-restrictive silencing factor regulates expansion of adult mouse subventricular zone-derived neural stem/progenitor cells in vitro.

Soldati C, Caramanica P, Burney MJ, Toselli C, Bithell A, Augusti-Tocco G, Stanton LW, Biagioni S, Buckley NJ, Cacci E.

J Neurosci Res. 2015 Aug;93(8):1203-14. doi: 10.1002/jnr.23572. Epub 2015 Feb 17.

PMID:
25691247
27.

NeuO: a fluorescent chemical probe for live neuron labeling.

Er JC, Leong C, Teoh CL, Yuan Q, Merchant P, Dunn M, Sulzer D, Sames D, Bhinge A, Kim D, Kim SM, Yoon MH, Stanton LW, Je SH, Yun SW, Chang YT.

Angew Chem Int Ed Engl. 2015 Feb 16;54(8):2442-6. doi: 10.1002/anie.201408614. Epub 2015 Jan 7.

PMID:
25565332
28.

Pleiotropic functions for transcription factor zscan10.

Kraus P, V S, Yu HB, Xing X, Lim SL, Adler T, Pimentel JA, Becker L, Bohla A, Garrett L, Hans W, Hölter SM, Janas E, Moreth K, Prehn C, Puk O, Rathkolb B, Rozman J, Adamski J, Bekeredjian R, Busch DH, Graw J, Klingenspor M, Klopstock T, Neff F, Ollert M, Stoeger T, Yildrim AÖ, Eickelberg O, Wolf E, Wurst W, Fuchs H, Gailus-Durner V, de Angelis MH, Lufkin T, Stanton LW.

PLoS One. 2014 Aug 11;9(8):e104568. doi: 10.1371/journal.pone.0104568. eCollection 2014. Erratum in: PLoS One. 2015;10(3):e0118766.

29.

MiR-135b is a direct PAX6 target and specifies human neuroectoderm by inhibiting TGF-β/BMP signaling.

Bhinge A, Poschmann J, Namboori SC, Tian X, Jia Hui Loh S, Traczyk A, Prabhakar S, Stanton LW.

EMBO J. 2014 Jun 2;33(11):1271-83. doi: 10.1002/embj.201387215. Epub 2014 May 6.

30.

Klf4 and Klf5 differentially inhibit mesoderm and endoderm differentiation in embryonic stem cells.

Aksoy I, Giudice V, Delahaye E, Wianny F, Aubry M, Mure M, Chen J, Jauch R, Bogu GK, Nolden T, Himmelbauer H, Xavier Doss M, Sachinidis A, Schulz H, Hummel O, Martinelli P, Hübner N, Stanton LW, Real FX, Bourillot PY, Savatier P.

Nat Commun. 2014 Apr 28;5:3719. doi: 10.1038/ncomms4719.

PMID:
24770696
31.

Transcription factor-induced lineage programming of noradrenaline and motor neurons from embryonic stem cells.

Mong J, Panman L, Alekseenko Z, Kee N, Stanton LW, Ericson J, Perlmann T.

Stem Cells. 2014 Mar;32(3):609-22. doi: 10.1002/stem.1585.

32.

Genome wide analysis reveals Zic3 interaction with distal regulatory elements of stage specific developmental genes in zebrafish.

Winata CL, Kondrychyn I, Kumar V, Srinivasan KG, Orlov Y, Ravishankar A, Prabhakar S, Stanton LW, Korzh V, Mathavan S.

PLoS Genet. 2013 Oct;9(10):e1003852. doi: 10.1371/journal.pgen.1003852. Epub 2013 Oct 31.

33.

Sox transcription factors require selective interactions with Oct4 and specific transactivation functions to mediate reprogramming.

Aksoy I, Jauch R, Eras V, Chng WB, Chen J, Divakar U, Ng CK, Kolatkar PR, Stanton LW.

Stem Cells. 2013 Dec;31(12):2632-46. doi: 10.1002/stem.1522.

34.

The long noncoding RNA RMST interacts with SOX2 to regulate neurogenesis.

Ng SY, Bogu GK, Soh BS, Stanton LW.

Mol Cell. 2013 Aug 8;51(3):349-59. doi: 10.1016/j.molcel.2013.07.017.

35.

An epigenetic signature of developmental potential in neural stem cells and early neurons.

Burney MJ, Johnston C, Wong KY, Teng SW, Beglopoulos V, Stanton LW, Williams BP, Bithell A, Buckley NJ.

Stem Cells. 2013 Sep;31(9):1868-80. doi: 10.1002/stem.1431.

36.

Pluripotency-regulating networks provide basis for reprogramming.

Aksoy I, Stanton LW.

Curr Mol Med. 2013 Jun;13(5):695-706. Review.

PMID:
23642069
37.

Long noncoding RNAs in development and disease of the central nervous system.

Ng SY, Lin L, Soh BS, Stanton LW.

Trends Genet. 2013 Aug;29(8):461-8. doi: 10.1016/j.tig.2013.03.002. Epub 2013 Apr 4. Review.

PMID:
23562612
38.

Oct4 switches partnering from Sox2 to Sox17 to reinterpret the enhancer code and specify endoderm.

Aksoy I, Jauch R, Chen J, Dyla M, Divakar U, Bogu GK, Teo R, Leng Ng CK, Herath W, Lili S, Hutchins AP, Robson P, Kolatkar PR, Stanton LW.

EMBO J. 2013 Apr 3;32(7):938-53. doi: 10.1038/emboj.2013.31. Epub 2013 Mar 8.

39.

Nanofibrous scaffold-mediated REST knockdown to enhance neuronal differentiation of stem cells.

Low WC, Rujitanaroj PO, Lee DK, Messersmith PB, Stanton LW, Goh E, Chew SY.

Biomaterials. 2013 May;34(14):3581-90. doi: 10.1016/j.biomaterials.2013.01.093. Epub 2013 Feb 14.

PMID:
23415645
40.

Dysregulation of REST-regulated coding and non-coding RNAs in a cellular model of Huntington's disease.

Soldati C, Bithell A, Johnston C, Wong KY, Stanton LW, Buckley NJ.

J Neurochem. 2013 Feb;124(3):418-30. doi: 10.1111/jnc.12090.

41.

Long non-coding RNAs in stem cell pluripotency.

Ng SY, Stanton LW.

Wiley Interdiscip Rev RNA. 2013 Jan-Feb;4(1):121-8. doi: 10.1002/wrna.1146. Epub 2012 Nov 8.

PMID:
23139157
42.

Widespread binding of FUS along nascent RNA regulates alternative splicing in the brain.

Rogelj B, Easton LE, Bogu GK, Stanton LW, Rot G, Curk T, Zupan B, Sugimoto Y, Modic M, Haberman N, Tollervey J, Fujii R, Takumi T, Shaw CE, Ule J.

Sci Rep. 2012;2:603. doi: 10.1038/srep00603. Epub 2012 Aug 28.

43.

Activin and BMP4 synergistically promote formation of definitive endoderm in human embryonic stem cells.

Teo AK, Ali Y, Wong KY, Chipperfield H, Sadasivam A, Poobalan Y, Tan EK, Wang ST, Abraham S, Tsuneyoshi N, Stanton LW, Dunn NR.

Stem Cells. 2012 Apr;30(4):631-42. doi: 10.1002/stem.1022.

44.

Structural analysis and dimerization profile of the SCAN domain of the pluripotency factor Zfp206.

Liang Y, Huimei Hong F, Ganesan P, Jiang S, Jauch R, Stanton LW, Kolatkar PR.

Nucleic Acids Res. 2012 Sep 1;40(17):8721-32. Epub 2012 Jun 26.

45.

Neural stem cell specific fluorescent chemical probe binding to FABP7.

Yun SW, Leong C, Zhai D, Tan YL, Lim L, Bi X, Lee JJ, Kim HJ, Kang NY, Ng SH, Stanton LW, Chang YT.

Proc Natl Acad Sci U S A. 2012 Jun 26;109(26):10214-7. doi: 10.1073/pnas.1200817109. Epub 2012 Jun 11.

46.

A genome-wide screen for genetic variants that modify the recruitment of REST to its target genes.

Johnson R, Richter N, Bogu GK, Bhinge A, Teng SW, Choo SH, Andrieux LO, de Benedictis C, Jauch R, Stanton LW.

PLoS Genet. 2012;8(4):e1002624. doi: 10.1371/journal.pgen.1002624. Epub 2012 Apr 5.

47.

Identification and characterization of mesenchymal stem cells derived from the trabecular meshwork of the human eye.

Tay CY, Sathiyanathan P, Chu SW, Stanton LW, Wong TT.

Stem Cells Dev. 2012 Jun 10;21(9):1381-90. doi: 10.1089/scd.2011.0655. Epub 2012 Apr 16.

PMID:
22364584
48.

Directing neuronal differentiation of primary neural progenitor cells by gene knockdown approach.

Low WC, Yau WW, Stanton LW, Marcy G, Goh E, Chew SY.

DNA Cell Biol. 2012 Jul;31(7):1148-60. doi: 10.1089/dna.2011.1557. Epub 2012 Feb 17.

49.

Human long non-coding RNAs promote pluripotency and neuronal differentiation by association with chromatin modifiers and transcription factors.

Ng SY, Johnson R, Stanton LW.

EMBO J. 2012 Feb 1;31(3):522-33. doi: 10.1038/emboj.2011.459. Epub 2011 Dec 23.

50.

Repressor element 1 silencing transcription factor couples loss of pluripotency with neural induction and neural differentiation.

Soldati C, Bithell A, Johnston C, Wong KY, Teng SW, Beglopoulos V, Stanton LW, Buckley NJ.

Stem Cells. 2012 Mar;30(3):425-34. doi: 10.1002/stem.1004.

Supplemental Content

Loading ...
Support Center