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Items: 1 to 50 of 79

1.

Protein kinase C regulates ErbB3 turnover.

Dietrich M, Malik MS, Skeie M, Bertelsen V, Stang E.

Exp Cell Res. 2019 Sep 15;382(2):111473. doi: 10.1016/j.yexcr.2019.06.018. Epub 2019 Jun 21.

PMID:
31233741
2.

Protein kinase C mediated internalization of ErbB2 is independent of clathrin, ubiquitination and Hsp90 dissociation.

Dietrich M, Malik MS, Nikolaysen F, Skeie M, Stang E.

Exp Cell Res. 2018 Oct 1;371(1):139-150. doi: 10.1016/j.yexcr.2018.08.004. Epub 2018 Aug 8.

PMID:
30098331
3.

Macrocyclic pyrrolobenzodiazepine dimers as antibody-drug conjugate payloads.

Donnell AF, Zhang Y, Stang EM, Wei DD, Tebben AJ, Perez HL, Schroeder GM, Pan C, Rao C, Borzilleri RM, Vite GD, Gangwar S.

Bioorg Med Chem Lett. 2017 Dec 1;27(23):5267-5271. doi: 10.1016/j.bmcl.2017.10.028. Epub 2017 Oct 16.

PMID:
29102228
4.

ErbB3 interacts with Hrs and is sorted to lysosomes for degradation.

Fosdahl AM, Dietrich M, Schink KO, Malik MS, Skeie M, Bertelsen V, Stang E.

Biochim Biophys Acta Mol Cell Res. 2017 Dec;1864(12):2241-2252. doi: 10.1016/j.bbamcr.2017.08.011. Epub 2017 Sep 1.

5.

A combination of two antibodies recognizing non-overlapping epitopes of HER2 induces kinase activity-dependent internalization of HER2.

Szymanska M, Fosdahl AM, Nikolaysen F, Pedersen MW, Grandal MM, Stang E, Bertelsen V.

J Cell Mol Med. 2016 Oct;20(10):1999-2011. doi: 10.1111/jcmm.12899. Epub 2016 Jul 28.

6.

Interaction with epsin 1 regulates the constitutive clathrin-dependent internalization of ErbB3.

Szymanska M, Fosdahl AM, Raiborg C, Dietrich M, Liestøl K, Stang E, Bertelsen V.

Biochim Biophys Acta. 2016 Jun;1863(6 Pt A):1179-88. doi: 10.1016/j.bbamcr.2016.03.011. Epub 2016 Mar 11.

7.

CTGF/CCN2 Postconditioning Increases Tolerance of Murine Hearts towards Ischemia-Reperfusion Injury.

Kaasbøll OJ, Moe IT, Ahmed MS, Stang E, Hagelin EM, Attramadal H.

PLoS One. 2016 Feb 12;11(2):e0149000. doi: 10.1371/journal.pone.0149000. eCollection 2016.

8.

Syndecan-4 Regulates Muscle Differentiation and Is Internalized from the Plasma Membrane during Myogenesis.

Rønning SB, Carlson CR, Stang E, Kolset SO, Hollung K, Pedersen ME.

PLoS One. 2015 Jun 12;10(6):e0129288. doi: 10.1371/journal.pone.0129288. eCollection 2015.

9.

Neonatal Abstinence Syndrome: Influence of a Combined Inpatient/Outpatient Methadone Treatment Regimen on the Average Length of Stay of a Medicaid NICU Population.

Lee J, Hulman S, Musci M Jr, Stang E.

Popul Health Manag. 2015 Oct;18(5):392-7. doi: 10.1089/pop.2014.0134. Epub 2015 Mar 24.

10.

Discovery of tetrahydroisoquinoline-based bivalent heterodimeric IAP antagonists.

Kim KS, Zhang L, Williams D, Perez HL, Stang E, Borzilleri RM, Posy S, Lei M, Chaudhry C, Emanuel S, Talbott R.

Bioorg Med Chem Lett. 2014 Nov 1;24(21):5022-9. doi: 10.1016/j.bmcl.2014.09.022. Epub 2014 Sep 16.

PMID:
25278234
11.
12.

The Mysterious Ways of ErbB2/HER2 Trafficking.

Bertelsen V, Stang E.

Membranes (Basel). 2014 Aug 6;4(3):424-46. doi: 10.3390/membranes4030424. Review.

13.

Pertuzumab counteracts the inhibitory effect of ErbB2 on degradation of ErbB3.

Sak MM, Szymanska M, Bertelsen V, Hasmann M, Madshus IH, Stang E.

Carcinogenesis. 2013 Sep;34(9):2031-8. doi: 10.1093/carcin/bgt173. Epub 2013 May 22.

PMID:
23698633
14.

Preubiquitinated chimeric ErbB2 is constitutively endocytosed and subsequently degraded in lysosomes.

Vuong TT, Berger C, Bertelsen V, Rødland MS, Stang E, Madshus IH.

Exp Cell Res. 2013 Feb 1;319(3):32-45. doi: 10.1016/j.yexcr.2012.10.010. Epub 2012 Nov 2.

PMID:
23127513
15.

Cetuximab in combination with anti-human IgG antibodies efficiently down-regulates the EGF receptor by macropinocytosis.

Berger C, Madshus IH, Stang E.

Exp Cell Res. 2012 Dec 10;318(20):2578-91. doi: 10.1016/j.yexcr.2012.09.001. Epub 2012 Sep 11.

PMID:
22975728
16.

Statins affect the presentation of endothelial chemokines by targeting to multivesicular bodies.

Hol J, Otterdal K, Breland UM, Stang E, Pedersen TM, Hagelsteen K, Ranheim T, Kasprzycka M, Halvorsen B, Haraldsen G, Aukrust P.

PLoS One. 2012;7(7):e40673. doi: 10.1371/journal.pone.0040673. Epub 2012 Jul 16.

17.

The oncoprotein ErbB3 is endocytosed in the absence of added ligand in a clathrin-dependent manner.

Sak MM, Breen K, Rønning SB, Pedersen NM, Bertelsen V, Stang E, Madshus IH.

Carcinogenesis. 2012 May;33(5):1031-9. doi: 10.1093/carcin/bgs128. Epub 2012 Mar 20.

PMID:
22436610
18.

Pertuzumab Increases 17-AAG-Induced Degradation of ErbB2, and This Effect Is Further Increased by Combining Pertuzumab with Trastuzumab.

Hughes JB, Rødland MS, Hasmann M, Madshus IH, Stang E.

Pharmaceuticals (Basel). 2012 Jun 28;5(7):674-89. doi: 10.3390/ph5070674.

19.

Molecular complexity via C-H activation: a dehydrogenative Diels-Alder reaction.

Stang EM, White MC.

J Am Chem Soc. 2011 Sep 28;133(38):14892-5. doi: 10.1021/ja2059704. Epub 2011 Sep 1.

20.

Surveillance of female patients with inherited bleeding disorders in United States Haemophilia Treatment Centres.

Byams VR, Kouides PA, Kulkarni R, Baker JR, Brown DL, Gill JC, Grant AM, James AH, Konkle BA, Maahs J, Dumas MM, McAlister S, Nance D, Nugent D, Philipp CS, Soucie JM, Stang E; Haemophilia Treatment Centres Network Investigators.

Haemophilia. 2011 Jul;17 Suppl 1:6-13. doi: 10.1111/j.1365-2516.2011.02558.x.

21.

Nimotuzumab and cetuximab block ligand-independent EGF receptor signaling efficiently at different concentrations.

Berger C, Krengel U, Stang E, Moreno E, Madshus IH.

J Immunother. 2011 Sep;34(7):550-5. doi: 10.1097/CJI.0b013e31822a5ca6.

PMID:
21760527
22.

CIN85 regulates ubiquitination and degradative endosomal sorting of the EGF receptor.

Rønning SB, Pedersen NM, Madshus IH, Stang E.

Exp Cell Res. 2011 Aug 1;317(13):1804-16. doi: 10.1016/j.yexcr.2011.05.016. Epub 2011 May 20.

PMID:
21635887
23.

On the macrocyclization of the erythromycin core: preorganization is not required.

Stang EM, White MC.

Angew Chem Int Ed Engl. 2011 Feb 25;50(9):2094-7. doi: 10.1002/anie.201007309. Epub 2011 Jan 27. No abstract available.

24.

A chimeric pre-ubiquitinated EGF receptor is constitutively endocytosed in a clathrin-dependent, but kinase-independent manner.

Bertelsen V, Sak MM, Breen K, Rødland MS, Johannessen LE, Traub LM, Stang E, Madshus IH.

Traffic. 2011 Apr;12(4):507-20. doi: 10.1111/j.1600-0854.2011.01162.x. Epub 2011 Feb 8.

25.

Decorin accumulation contributes to the stromal opacities found in congenital stromal corneal dystrophy.

Bredrup C, Stang E, Bruland O, Palka BP, Young RD, Haavik J, Knappskog PM, Rødahl E.

Invest Ophthalmol Vis Sci. 2010 Nov;51(11):5578-82. doi: 10.1167/iovs.09-4933. Epub 2010 May 19.

PMID:
20484579
26.

Total synthesis and study of 6-deoxyerythronolide B by late-stage C-H oxidation.

Stang EM, White MC.

Nat Chem. 2009 Oct;1(7):547-51. doi: 10.1038/nchem.351. Epub 2009 Aug 30.

27.
28.

Pertuzumab increases epidermal growth factor receptor down-regulation by counteracting epidermal growth factor receptor-ErbB2 heterodimerization.

Hughes JB, Berger C, Rødland MS, Hasmann M, Stang E, Madshus IH.

Mol Cancer Ther. 2009 Jul;8(7):1885-92. doi: 10.1158/1535-7163.MCT-09-0291. Epub 2009 Jul 7.

29.

Expression of epidermal growth factor receptor or ErbB3 facilitates geldanamycin-induced down-regulation of ErbB2.

Pedersen NM, Breen K, Rødland MS, Haslekås C, Stang E, Madshus IH.

Mol Cancer Res. 2009 Feb;7(2):275-84. doi: 10.1158/1541-7786.MCR-07-2183. Epub 2009 Feb 10.

30.

Epsin 1 is involved in recruitment of ubiquitinated EGF receptors into clathrin-coated pits.

Kazazic M, Bertelsen V, Pedersen KW, Vuong TT, Grandal MV, Rødland MS, Traub LM, Stang E, Madshus IH.

Traffic. 2009 Feb;10(2):235-45. doi: 10.1111/j.1600-0854.2008.00858.x. Epub 2008 Nov 20.

31.

An endosomally localized isoform of Eps15 interacts with Hrs to mediate degradation of epidermal growth factor receptor.

Roxrud I, Raiborg C, Pedersen NM, Stang E, Stenmark H.

J Cell Biol. 2008 Mar 24;180(6):1205-18. doi: 10.1083/jcb.200708115.

32.

Geldanamycin-induced down-regulation of ErbB2 from the plasma membrane is clathrin dependent but proteasomal activity independent.

Pedersen NM, Madshus IH, Haslekås C, Stang E.

Mol Cancer Res. 2008 Mar;6(3):491-500. doi: 10.1158/1541-7786.MCR-07-0191.

33.

Dysregulation of Ack1 inhibits down-regulation of the EGF receptor.

Grøvdal LM, Johannessen LE, Rødland MS, Madshus IH, Stang E.

Exp Cell Res. 2008 Apr 1;314(6):1292-300. doi: 10.1016/j.yexcr.2007.12.017. Epub 2008 Jan 5.

PMID:
18262180
34.

The Cbl-interacting protein TULA inhibits dynamin-dependent endocytosis.

Bertelsen V, Breen K, Sandvig K, Stang E, Madshus IH.

Exp Cell Res. 2007 May 1;313(8):1696-709. Epub 2007 Feb 28.

PMID:
17382318
35.

EGF-induced activation of the EGF receptor does not trigger mobilization of caveolae.

Kazazic M, Roepstorff K, Johannessen LE, Pedersen NM, van Deurs B, Stang E, Madshus IH.

Traffic. 2006 Nov;7(11):1518-27. Epub 2006 Sep 19.

36.

Platelet-derived LIGHT induces inflammatory responses in endothelial cells and monocytes.

Otterdal K, Smith C, Oie E, Pedersen TM, Yndestad A, Stang E, Endresen K, Solum NO, Aukrust P, Damås JK.

Blood. 2006 Aug 1;108(3):928-35.

37.

Both clathrin-positive and -negative coats are involved in endosomal sorting of the EGF receptor.

Myromslien FD, Grøvdal LM, Raiborg C, Stenmark H, Madshus IH, Stang E.

Exp Cell Res. 2006 Oct 1;312(16):3036-48. Epub 2006 Jun 8.

PMID:
16859684
38.

Activation of the epidermal growth factor (EGF) receptor induces formation of EGF receptor- and Grb2-containing clathrin-coated pits.

Johannessen LE, Pedersen NM, Pedersen KW, Madshus IH, Stang E.

Mol Cell Biol. 2006 Jan;26(2):389-401.

39.
40.

Herceptin-induced inhibition of ErbB2 signaling involves reduced phosphorylation of Akt but not endocytic down-regulation of ErbB2.

Longva KE, Pedersen NM, Haslekås C, Stang E, Madshus IH.

Int J Cancer. 2005 Sep 1;116(3):359-67.

41.

Direct interaction of Cbl with pTyr 1045 of the EGF receptor (EGFR) is required to sort the EGFR to lysosomes for degradation.

Grøvdal LM, Stang E, Sorkin A, Madshus IH.

Exp Cell Res. 2004 Nov 1;300(2):388-95.

PMID:
15475003
42.

Cbl-dependent ubiquitination is required for progression of EGF receptors into clathrin-coated pits.

Stang E, Blystad FD, Kazazic M, Bertelsen V, Brodahl T, Raiborg C, Stenmark H, Madshus IH.

Mol Biol Cell. 2004 Aug;15(8):3591-604. Epub 2004 Jun 11.

43.

Mutants of the protein serine kinase PSKH1 disassemble the Golgi apparatus.

Brede G, Solheim J, Stang E, Prydz H.

Exp Cell Res. 2003 Dec 10;291(2):299-312.

PMID:
14644153
44.

Inhibitors of COP-mediated transport and cholera toxin action inhibit simian virus 40 infection.

Richards AA, Stang E, Pepperkok R, Parton RG.

Mol Biol Cell. 2002 May;13(5):1750-64.

45.

Hrs sorts ubiquitinated proteins into clathrin-coated microdomains of early endosomes.

Raiborg C, Bache KG, Gillooly DJ, Madshus IH, Stang E, Stenmark H.

Nat Cell Biol. 2002 May;4(5):394-8.

PMID:
11988743
46.

Cholesterol is important in control of EGF receptor kinase activity but EGF receptors are not concentrated in caveolae.

Ringerike T, Blystad FD, Levy FO, Madshus IH, Stang E.

J Cell Sci. 2002 Mar 15;115(Pt 6):1331-40.

47.

Ubiquitination and proteasomal activity is required for transport of the EGF receptor to inner membranes of multivesicular bodies.

Longva KE, Blystad FD, Stang E, Larsen AM, Johannessen LE, Madshus IH.

J Cell Biol. 2002 Mar 4;156(5):843-54. Epub 2002 Feb 25.

48.

Localizing the EGF receptor.

Oksvold M, Huitfeldt H, Stang E, Madshus I.

Nat Cell Biol. 2002 Feb;4(2):E22; author reply E22-3. No abstract available.

PMID:
11835048
49.

Hrs recruits clathrin to early endosomes.

Raiborg C, Bache KG, Mehlum A, Stang E, Stenmark H.

EMBO J. 2001 Sep 3;20(17):5008-21.

50.

FYVE and coiled-coil domains determine the specific localisation of Hrs to early endosomes.

Raiborg C, Bremnes B, Mehlum A, Gillooly DJ, D'Arrigo A, Stang E, Stenmark H.

J Cell Sci. 2001 Jun;114(Pt 12):2255-63.

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