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Items: 1 to 50 of 297

1.

Newcastle disease virus degrades HIF-1α through proteasomal pathways independent of VHL and p53.

Abd-Aziz N, Stanbridge EJ, Shafee N.

J Gen Virol. 2016 Dec;97(12):3174-3182. doi: 10.1099/jgv.0.000623. Epub 2016 Oct 6.

2.

Bortezomib attenuates HIF-1- but not HIF-2-mediated transcriptional activation.

Abd-Aziz N, Stanbridge EJ, Shafee N.

Oncol Lett. 2015 Oct;10(4):2192-2196. Epub 2015 Jul 29.

3.

Human renal carcinoma cells respond to Newcastle disease virus infection through activation of the p38 MAPK/NF-κB/IκBα pathway.

Ch'ng WC, Abd-Aziz N, Ong MH, Stanbridge EJ, Shafee N.

Cell Oncol (Dordr). 2015 Aug;38(4):279-88. doi: 10.1007/s13402-015-0229-5. Epub 2015 May 1.

PMID:
25930675
4.

Anti-angiogenic pathway associations of the 3p21.3 mapped BLU gene in nasopharyngeal carcinoma.

Cheng Y, Ho RL, Chan KC, Kan R, Tung E, Lung HL, Yau WL, Cheung AK, Ko JM, Zhang ZF, Luo DZ, Feng ZB, Chen S, Guan XY, Kwong D, Stanbridge EJ, Lung ML.

Oncogene. 2015 Aug 6;34(32):4219-28. doi: 10.1038/onc.2014.353. Epub 2014 Oct 27.

5.

The oncolytic activity of Newcastle disease virus in clear cell renal carcinoma cells in normoxic and hypoxic conditions: the interplay between von Hippel-Lindau and interferon-β signaling.

Ch'ng WC, Stanbridge EJ, Yusoff K, Shafee N.

J Interferon Cytokine Res. 2013 Jul;33(7):346-54. doi: 10.1089/jir.2012.0095. Epub 2013 Mar 18.

6.

Endocervical glandular neoplasia associated with lobular endocervical glandular hyperplasia is HPV-independent and correlates with carbonic anhydrase-IX expression: a Gynaecological Oncology Group Study.

Liao SY, Rodgers WH, Kauderer J, Darcy KM, Carter R, Susumu N, Nagao S, Walker JL, Hatae M, Stanbridge EJ.

Br J Cancer. 2013 Feb 19;108(3):613-20. doi: 10.1038/bjc.2012.578. Epub 2013 Jan 8.

7.

A modified Latent Class Model assessment of human papillomavirus-based screening tests for cervical lesions in women with atypical glandular cells: a Gynecologic Oncology Group study.

Carter RL, Kang L, Darcy KM, Kauderer J, Liao SY, Rodgers WH, Walker JL, Lankes HA, Dunn ST, Stanbridge EJ.

Cancer Causes Control. 2012 Dec;23(12):2013-21. doi: 10.1007/s10552-012-0081-0. Epub 2012 Oct 17.

8.

Hypoxia affects cellular responses to plant extracts.

Liew SY, Stanbridge EJ, Yusoff K, Shafee N.

J Ethnopharmacol. 2012 Nov 21;144(2):453-6. doi: 10.1016/j.jep.2012.09.024. Epub 2012 Sep 26.

PMID:
23022321
9.

Immunization with recombinant enterovirus 71 viral capsid protein 1 fragment stimulated antibody responses in hamsters.

Ch'ng WC, Stanbridge EJ, Wong KT, Ong KC, Yusoff K, Shafee N.

Virol J. 2012 Aug 9;9:155. doi: 10.1186/1743-422X-9-155.

10.

LTBP-2 confers pleiotropic suppression and promotes dormancy in a growth factor permissive microenvironment in nasopharyngeal carcinoma.

Chen H, Ko JM, Wong VC, Hyytiainen M, Keski-Oja J, Chua D, Nicholls JM, Cheung FM, Lee AW, Kwong DL, Chiu PM, Zabarovsky ER, Tsao SW, Tao Q, Kan R, Chan SH, Stanbridge EJ, Lung ML.

Cancer Lett. 2012 Dec 1;325(1):89-98. doi: 10.1016/j.canlet.2012.06.005. Epub 2012 Jun 26.

PMID:
22743615
11.

Selective growth inhibition by glycogen synthase kinase-3 inhibitors in tumorigenic HeLa hybrid cells is mediated through NF-κB-dependent GLUT3 expression.

Watanabe M, Abe N, Oshikiri Y, Stanbridge EJ, Kitagawa T.

Oncogenesis. 2012 Jul 9;1:e21. doi: 10.1038/oncsis.2012.21.

12.

Tumor suppressor Alpha B-crystallin (CRYAB) associates with the cadherin/catenin adherens junction and impairs NPC progression-associated properties.

Huang Z, Cheng Y, Chiu PM, Cheung FM, Nicholls JM, Kwong DL, Lee AW, Zabarovsky ER, Stanbridge EJ, Lung HL, Lung ML.

Oncogene. 2012 Aug 9;31(32):3709-20. doi: 10.1038/onc.2011.529. Epub 2011 Dec 12.

PMID:
22158051
13.

Deciphering the molecular genetic basis of NPC through functional approaches.

Lung HL, Cheung AK, Ko JM, Cheng Y, Stanbridge EJ, Lung ML.

Semin Cancer Biol. 2012 Apr;22(2):87-95. doi: 10.1016/j.semcancer.2011.11.002. Epub 2011 Dec 2. Review.

PMID:
22154888
14.

The LIM domain protein, CRIP2, promotes apoptosis in esophageal squamous cell carcinoma.

Lo PH, Ko JM, Yu ZY, Law S, Wang LD, Li JL, Srivastava G, Tsao SW, Stanbridge EJ, Lung ML.

Cancer Lett. 2012 Mar;316(1):39-45. doi: 10.1016/j.canlet.2011.10.020. Epub 2011 Oct 20.

PMID:
22154084
15.

Partial protection against enterovirus 71 (EV71) infection in a mouse model immunized with recombinant Newcastle disease virus capsids displaying the EV71 VP1 fragment.

Ch'ng WC, Stanbridge EJ, Ong KC, Wong KT, Yusoff K, Shafee N.

J Med Virol. 2011 Oct;83(10):1783-91. doi: 10.1002/jmv.22198.

PMID:
21837796
16.

Anti-angiogenic and tumor-suppressive roles of candidate tumor-suppressor gene, Fibulin-2, in nasopharyngeal carcinoma.

Law EW, Cheung AK, Kashuba VI, Pavlova TV, Zabarovsky ER, Lung HL, Cheng Y, Chua D, Lai-Wan Kwong D, Tsao SW, Sasaki T, Stanbridge EJ, Lung ML.

Oncogene. 2012 Feb 9;31(6):728-38. doi: 10.1038/onc.2011.272. Epub 2011 Jul 11.

PMID:
21743496
17.

Cysteine-rich intestinal protein 2 (CRIP2) acts as a repressor of NF-kappaB-mediated proangiogenic cytokine transcription to suppress tumorigenesis and angiogenesis.

Cheung AK, Ko JM, Lung HL, Chan KW, Stanbridge EJ, Zabarovsky E, Tokino T, Kashima L, Suzuki T, Kwong DL, Chua D, Tsao SW, Lung ML.

Proc Natl Acad Sci U S A. 2011 May 17;108(20):8390-5. doi: 10.1073/pnas.1101747108. Epub 2011 May 3.

18.

Tumor suppressor dual-specificity phosphatase 6 (DUSP6) impairs cell invasion and epithelial-mesenchymal transition (EMT)-associated phenotype.

Wong VC, Chen H, Ko JM, Chan KW, Chan YP, Law S, Chua D, Kwong DL, Lung HL, Srivastava G, Tang JC, Tsao SW, Zabarovsky ER, Stanbridge EJ, Lung ML.

Int J Cancer. 2012 Jan 1;130(1):83-95. doi: 10.1002/ijc.25970. Epub 2011 Apr 20.

19.

Abrogated expression of DEC1 during oesophageal squamous cell carcinoma progression is age- and family history-related and significantly associated with lymph node metastasis.

Wong VC, Ko JM, Qi RZ, Li PJ, Wang LD, Li JL, Chan YP, Chan KW, Stanbridge EJ, Lung ML.

Br J Cancer. 2011 Mar 1;104(5):841-9. doi: 10.1038/bjc.2011.25. Epub 2011 Feb 15.

20.

Catalytic activity of Matrix metalloproteinase-19 is essential for tumor suppressor and anti-angiogenic activities in nasopharyngeal carcinoma.

Chan KC, Ko JM, Lung HL, Sedlacek R, Zhang ZF, Luo DZ, Feng ZB, Chen S, Chen H, Chan KW, Tsao SW, Chua DT, Zabarovsky ER, Stanbridge EJ, Lung ML.

Int J Cancer. 2011 Oct 15;129(8):1826-37. doi: 10.1002/ijc.25855. Epub 2011 Apr 1.

21.

Carbonic anhydrase IX (CA-IX) and high-risk human papillomavirus (H-HPV) as diagnostic biomarkers of cervical dysplasia/neoplasia in Japanese women with a cytologic diagnosis of atypical glandular cells (AGC): a Gynecologic Oncology Group (GOG) Study.

Liao SY, Rodgers WH, Kauderer J, Bonfiglio TA, Darcy KM, Carter R, Levine L, Spirtos NM, Susumu N, Fujiwara K, Walker JL, Hatae M, Stanbridge EJ.

Br J Cancer. 2011 Jan 18;104(2):353-60. doi: 10.1038/sj.bjc.6606049. Epub 2010 Dec 14.

22.

The ECM protein LTBP-2 is a suppressor of esophageal squamous cell carcinoma tumor formation but higher tumor expression associates with poor patient outcome.

Chan SH, Yee Ko JM, Chan KW, Chan YP, Tao Q, Hyytiainen M, Keski-Oja J, Law S, Srivastava G, Tang J, Tsao SW, Chen H, Stanbridge EJ, Lung ML.

Int J Cancer. 2011 Aug 1;129(3):565-73. doi: 10.1002/ijc.25698. Epub 2010 Nov 9.

23.

Mitogen-activated protein/extracellular signal-regulated kinase kinase 1act/tubulin interaction is an important determinant of mitotic stability in cultured HT1080 human fibrosarcoma cells.

Cao JN, Shafee N, Vickery L, Kaluz S, Ru N, Stanbridge EJ.

Cancer Res. 2010 Jul 15;70(14):6004-14. doi: 10.1158/0008-5472.CAN-09-4490. Epub 2010 Jun 22.

24.

Extracellular protease ADAMTS9 suppresses esophageal and nasopharyngeal carcinoma tumor formation by inhibiting angiogenesis.

Lo PH, Lung HL, Cheung AK, Apte SS, Chan KW, Kwong FM, Ko JM, Cheng Y, Law S, Srivastava G, Zabarovsky ER, Tsao SW, Tang JC, Stanbridge EJ, Lung ML.

Cancer Res. 2010 Jul 1;70(13):5567-76. doi: 10.1158/0008-5472.CAN-09-4510. Epub 2010 Jun 15.

25.

CADM1 interacts with Tiam1 and promotes invasive phenotype of human T-cell leukemia virus type I-transformed cells and adult T-cell leukemia cells.

Masuda M, Maruyama T, Ohta T, Ito A, Hayashi T, Tsukasaki K, Kamihira S, Yamaoka S, Hoshino H, Yoshida T, Watanabe T, Stanbridge EJ, Murakami Y.

J Biol Chem. 2010 May 14;285(20):15511-22. doi: 10.1074/jbc.M109.076653. Epub 2010 Mar 9.

26.

Functional characterization of THY1 as a tumor suppressor gene with antiinvasive activity in nasopharyngeal carcinoma.

Lung HL, Cheung AK, Cheng Y, Kwong FM, Lo PH, Law EW, Chua D, Zabarovsky ER, Wang N, Tsao SW, Stanbridge EJ, Lung ML.

Int J Cancer. 2010 Jul 15;127(2):304-12. doi: 10.1002/ijc.25047.

27.

Prognostic relevance of carbonic anhydrase-IX in high-risk, early-stage cervical cancer: a Gynecologic Oncology Group study.

Liao SY, Darcy KM, Randall LM, Tian C, Monk BJ, Burger RA, Fruehauf JP, Peters WA, Stock RJ, Stanbridge EJ.

Gynecol Oncol. 2010 Mar;116(3):452-8. doi: 10.1016/j.ygyno.2009.10.062. Epub 2009 Nov 13.

28.

Carbonic anhydrase IX and human papillomavirus as diagnostic biomarkers of cervical dysplasia/neoplasia in women with a cytologic diagnosis of atypical glandular cells: a Gynecologic Oncology Group study in United States.

Liao SY, Rodgers WH, Kauderer J, Bonfiglio TA, Walker JL, Darcy KM, Carter R, Hatae M, Levine L, Spirtos NM, Stanbridge EJ.

Int J Cancer. 2009 Nov 15;125(10):2434-40. doi: 10.1002/ijc.24615.

29.

Chromosome 14 transfer and functional studies identify a candidate tumor suppressor gene, mirror image polydactyly 1, in nasopharyngeal carcinoma.

Cheung AK, Lung HL, Ko JM, Cheng Y, Stanbridge EJ, Zabarovsky ER, Nicholls JM, Chua D, Tsao SW, Guan XY, Lung ML.

Proc Natl Acad Sci U S A. 2009 Aug 25;106(34):14478-83. doi: 10.1073/pnas.0900198106. Epub 2009 Aug 10.

30.

Chromosome 3p microsatellite allelotyping in neuroblastoma: a report on the technical hurdles.

Hoebeeck J, De Wilde B, Michels E, Combaret V, Yigit N, De Smet E, Van Roy N, Stanbridge E, Ru N, Laureys G, De Paepe A, Speleman F, Vandesompele J.

Cancer Invest. 2009 Oct;27(8):857-68. doi: 10.1080/07357900902769731.

PMID:
19544108
31.

Transcriptional control of the tumor- and hypoxia-marker carbonic anhydrase 9: A one transcription factor (HIF-1) show?

Kaluz S, Kaluzová M, Liao SY, Lerman M, Stanbridge EJ.

Biochim Biophys Acta. 2009 Apr;1795(2):162-72. doi: 10.1016/j.bbcan.2009.01.001. Epub 2009 Jan 22. Review.

32.

PI3K/Akt activity has variable cell-specific effects on expression of HIF target genes, CA9 and VEGF, in human cancer cell lines.

Shafee N, Kaluz S, Ru N, Stanbridge EJ.

Cancer Lett. 2009 Sep 8;282(1):109-15. doi: 10.1016/j.canlet.2009.03.004. Epub 2009 Apr 1.

33.

Expression of transmembrane carbonic anhydrases, CAIX and CAXII, in human development.

Liao SY, Lerman MI, Stanbridge EJ.

BMC Dev Biol. 2009 Mar 16;9:22. doi: 10.1186/1471-213X-9-22.

34.

Functional analysis of a cell cycle-associated, tumor-suppressive gene, protein tyrosine phosphatase receptor type G, in nasopharyngeal carcinoma.

Cheung AK, Lung HL, Hung SC, Law EW, Cheng Y, Yau WL, Bangarusamy DK, Miller LD, Liu ET, Shao JY, Kou CW, Chua D, Zabarovsky ER, Tsao SW, Stanbridge EJ, Lung ML.

Cancer Res. 2008 Oct 1;68(19):8137-45. doi: 10.1158/0008-5472.CAN-08-0904.

35.

Inactivation of the cystatin E/M tumor suppressor gene in cervical cancer.

Veena MS, Lee G, Keppler D, Mendonca MS, Redpath JL, Stanbridge EJ, Wilczynski SP, Srivatsan ES.

Genes Chromosomes Cancer. 2008 Sep;47(9):740-54. doi: 10.1002/gcc.20576.

36.

Regulation of gene expression by hypoxia: integration of the HIF-transduced hypoxic signal at the hypoxia-responsive element.

Kaluz S, Kaluzová M, Stanbridge EJ.

Clin Chim Acta. 2008 Sep;395(1-2):6-13. doi: 10.1016/j.cca.2008.05.002. Epub 2008 May 9. Review.

37.

Comment on the role of FIH in the inhibitory effect of bortezomib on hypoxia-inducible factor-1.

Kaluz S, Kaluzová M, Stanbridge EJ.

Blood. 2008 May 15;111(10):5258-9; author reply 5259-61. doi: 10.1182/blood-2008-02-140079. No abstract available.

PMID:
18467614
38.

Cancer stem cells contribute to cisplatin resistance in Brca1/p53-mediated mouse mammary tumors.

Shafee N, Smith CR, Wei S, Kim Y, Mills GB, Hortobagyi GN, Stanbridge EJ, Lee EY.

Cancer Res. 2008 May 1;68(9):3243-50. doi: 10.1158/0008-5472.CAN-07-5480.

39.

Characterization of a novel epigenetically-silenced, growth-suppressive gene, ADAMTS9, and its association with lymph node metastases in nasopharyngeal carcinoma.

Lung HL, Lo PHY, Xie D, Apte SS, Cheung AKL, Cheng Y, Law EWL, Chua D, Zeng YX, Tsao SW, Stanbridge EJ, Lung ML.

Int J Cancer. 2008 Jul 15;123(2):401-408. doi: 10.1002/ijc.23528.

40.

Monochromosome transfer and microarray analysis identify a critical tumor-suppressive region mapping to chromosome 13q14 and THSD1 in esophageal carcinoma.

Ko JM, Chan PL, Yau WL, Chan HK, Chan KC, Yu ZY, Kwong FM, Miller LD, Liu ET, Yang LC, Lo PH, Stanbridge EJ, Tang JC, Srivastava G, Tsao SW, Law S, Lung ML.

Mol Cancer Res. 2008 Apr;6(4):592-603. doi: 10.1158/1541-7786.MCR-07-0154.

41.

Rational design of minimal hypoxia-inducible enhancers.

Kaluz S, Kaluzová M, Stanbridge EJ.

Biochem Biophys Res Commun. 2008 Jun 13;370(4):613-8. doi: 10.1016/j.bbrc.2008.03.147. Epub 2008 Apr 8.

42.

p53-dependent Chk1 phosphorylation is required for maintenance of prolonged G2 Arrest.

Wang XQ, Stanbridge EJ, Lao X, Cai Q, Fan ST, Redpath JL.

Radiat Res. 2007 Dec;168(6):706-15.

PMID:
18088187
44.

Identification of tumor suppressive activity by irradiation microcell-mediated chromosome transfer and involvement of alpha B-crystallin in nasopharyngeal carcinoma.

Lung HL, Lo CC, Wong CC, Cheung AK, Cheong KF, Wong N, Kwong FM, Chan KC, Law EW, Tsao SW, Chua D, Sham JS, Cheng Y, Stanbridge EJ, Robertson GP, Lung ML.

Int J Cancer. 2008 Mar 15;122(6):1288-96.

45.

Potential histologic and molecular predictors of response to temsirolimus in patients with advanced renal cell carcinoma.

Cho D, Signoretti S, Dabora S, Regan M, Seeley A, Mariotti M, Youmans A, Polivy A, Mandato L, McDermott D, Stanbridge E, Atkins M.

Clin Genitourin Cancer. 2007 Sep;5(6):379-85.

PMID:
17956710
46.

Oncogenic K-Ras signals through epidermal growth factor receptor and wild-type H-Ras to promote radiation survival in pancreatic and colorectal carcinoma cells.

Cengel KA, Voong KR, Chandrasekaran S, Maggiorella L, Brunner TB, Stanbridge E, Kao GD, McKenna WG, Bernhard EJ.

Neoplasia. 2007 Apr;9(4):341-8.

47.

Mandatory chromosomal segment balance in aneuploid tumor cells.

Kost-Alimova M, Darai-Ramqvist E, Yau WL, Sandlund A, Fedorova L, Yang Y, Kholodnyuk I, Cheng Y, Li Lung M, Stanbridge E, Klein G, Imreh S.

BMC Cancer. 2007 Jan 26;7:21.

48.

TSLC1 is a tumor suppressor gene associated with metastasis in nasopharyngeal carcinoma.

Lung HL, Cheung AK, Xie D, Cheng Y, Kwong FM, Murakami Y, Guan XY, Sham JS, Chua D, Protopopov AI, Zabarovsky ER, Tsao SW, Stanbridge EJ, Lung ML.

Cancer Res. 2006 Oct 1;66(19):9385-92.

49.

Functional studies of the chromosome 3p21.3 candidate tumor suppressor gene BLU/ZMYND10 in nasopharyngeal carcinoma.

Yau WL, Lung HL, Zabarovsky ER, Lerman MI, Sham JS, Chua DT, Tsao SW, Stanbridge EJ, Lung ML.

Int J Cancer. 2006 Dec 15;119(12):2821-6.

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