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Items: 1 to 50 of 171


Heterogeneity of adult masseter muscle satellite cells with cardiomyocyte differentiation potential.

Huang W, Liang J, Feng Y, Jia Z, Jiang L, Cai W, Paul C, Gu JG, Stambrook PJ, Millard RW, Zhu XL, Zhu P, Wang Y.

Exp Cell Res. 2018 Oct 1;371(1):20-30. doi: 10.1016/j.yexcr.2018.05.028. Epub 2018 May 26.


Loss of microRNA-128 promotes cardiomyocyte proliferation and heart regeneration.

Huang W, Feng Y, Liang J, Yu H, Wang C, Wang B, Wang M, Jiang L, Meng W, Cai W, Medvedovic M, Chen J, Paul C, Davidson WS, Sadayappan S, Stambrook PJ, Yu XY, Wang Y.

Nat Commun. 2018 Feb 16;9(1):700. doi: 10.1038/s41467-018-03019-z.


Towards precision prevention: Technologies for identifying healthy individuals with high risk of disease.

Nagel ZD, Engelward BP, Brenner DJ, Begley TJ, Sobol RW, Bielas JH, Stambrook PJ, Wei Q, Hu JJ, Terry MB, Dilworth C, McAllister KA, Reinlib L, Worth L, Shaughnessy DT.

Mutat Res. 2017 Aug;800-802:14-28. doi: 10.1016/j.mrfmmm.2017.03.007. Epub 2017 Apr 6. Review.


Cancer Immunotherapy: Whence and Whither.

Stambrook PJ, Maher J, Farzaneh F.

Mol Cancer Res. 2017 Jun;15(6):635-650. doi: 10.1158/1541-7786.MCR-16-0427. Epub 2017 Mar 29. Review.


Acetylation and deacetylation of Cdc25A constitutes a novel mechanism for modulating Cdc25A functions with implications for cancer.

Lozada EM, Andrysik Z, Yin M, Redilla N, Rice K, Stambrook PJ.

Oncotarget. 2016 Apr 12;7(15):20425-39. doi: 10.18632/oncotarget.7966.


Cytoskeletal architecture and cell motility remain unperturbed in mouse embryonic fibroblasts from Plk3 knockout mice.

Michel DR, Mun KS, Ho CC, Stambrook PJ.

Exp Biol Med (Maywood). 2016 Mar;241(6):603-10. doi: 10.1177/1535370216629010. Epub 2016 Feb 2.


Correction: Nuclear receptor LRH-1/NR5A2 is required and targetable for liver endoplasmic reticulum stress resolution.

Mamrosh JL, Lee JM, Wagner M, Stambrook PJ, Whitby RJ, Sifers RN, Wu SP, Tsai MJ, DeMayo FJ, Moore DD.

Elife. 2015 Jul 24;4:e10084. doi: 10.7554/eLife.10084. No abstract available.


Genomic signatures of near-extinction and rebirth of the crested ibis and other endangered bird species.

Li S, Li B, Cheng C, Xiong Z, Liu Q, Lai J, Carey HV, Zhang Q, Zheng H, Wei S, Zhang H, Chang L, Liu S, Zhang S, Yu B, Zeng X, Hou Y, Nie W, Guo Y, Chen T, Han J, Wang J, Wang J, Chen C, Liu J, Stambrook PJ, Xu M, Zhang G, Gilbert MT, Yang H, Jarvis ED, Yu J, Yan J.

Genome Biol. 2014;15(12):557.


Next-generation sequencing technologies: breaking the sound barrier of human genetics.

Bahassi el M, Stambrook PJ.

Mutagenesis. 2014 Sep;29(5):303-10. doi: 10.1093/mutage/geu031. Review.


Whole genome sequencing of glioblastoma multiforme identifies multiple structural variations involved in EGFR activation.

Furgason JM, Li W, Milholland B, Cross E, Li Y, McPherson CM, Warnick RE, Rixe O, Stambrook PJ, Vijg J, Bahassi el M.

Mutagenesis. 2014 Sep;29(5):341-50. doi: 10.1093/mutage/geu026. Epub 2014 Aug 6.


Nuclear receptor LRH-1/NR5A2 is required and targetable for liver endoplasmic reticulum stress resolution.

Mamrosh JL, Lee JM, Wagner M, Stambrook PJ, Whitby RJ, Sifers RN, Wu SP, Tsai MJ, Demayo FJ, Moore DD.

Elife. 2014 Apr 15;3:e01694. doi: 10.7554/eLife.01694. Erratum in: Elife. 2015;4:e10084.


Nuclear transfer between two species of Acetabularia.

Stambrook PJ.

Exp Biol Med (Maywood). 2013 Mar;238(3):257-8. doi: 10.1177/1535370213482084. No abstract available.


A patient-derived somatic mutation in the epidermal growth factor receptor ligand-binding domain confers increased sensitivity to cetuximab in head and neck cancer.

Bahassi el M, Li YQ, Wise-Draper TM, Deng L, Wang J, Darnell CN, Wilson KM, Wells SI, Stambrook PJ, Rixe O.

Eur J Cancer. 2013 Jul;49(10):2345-55. doi: 10.1016/j.ejca.2013.03.005. Epub 2013 Apr 8.


Mouse embryonic stem cells undergo charontosis, a novel programmed cell death pathway dependent upon cathepsins, p53, and EndoG, in response to etoposide treatment.

Tichy ED, Stephan ZA, Osterburg A, Noel G, Stambrook PJ.

Stem Cell Res. 2013 May;10(3):428-41. doi: 10.1016/j.scr.2013.01.010. Epub 2013 Feb 5.


The abundance of Rad51 protein in mouse embryonic stem cells is regulated at multiple levels.

Tichy ED, Pillai R, Deng L, Tischfield JA, Hexley P, Babcock GF, Stambrook PJ.

Stem Cell Res. 2012 Sep;9(2):124-34. doi: 10.1016/j.scr.2012.05.004. Epub 2012 May 22.


Ionizing radiation is a potent inducer of mitotic recombination in mouse embryonic stem cells.

Denissova NG, Tereshchenko IV, Cui E, Stambrook PJ, Shao C, Tischfield JA.

Mutat Res. 2011 Oct 1;715(1-2):1-6. doi: 10.1016/j.mrfmmm.2011.06.017. Epub 2011 Jul 23.


Functional and molecular interactions between ERK and CHK2 in diffuse large B-cell lymphoma.

Dai B, Zhao XF, Mazan-Mamczarz K, Hagner P, Corl S, Bahassi el M, Lu S, Stambrook PJ, Shapiro P, Gartenhaus RB.

Nat Commun. 2011 Jul 19;2:402. doi: 10.1038/ncomms1404.


The human DEK oncogene regulates DNA damage response signaling and repair.

Kavanaugh GM, Wise-Draper TM, Morreale RJ, Morrison MA, Gole B, Schwemberger S, Tichy ED, Lu L, Babcock GF, Wells JM, Drissi R, Bissler JJ, Stambrook PJ, Andreassen PR, Wiesmüller L, Wells SI.

Nucleic Acids Res. 2011 Sep 1;39(17):7465-76. doi: 10.1093/nar/gkr454. Epub 2011 Jun 7.


Absence of polo-like kinase 3 in mice stabilizes Cdc25A after DNA damage but is not sufficient to produce tumors.

Myer DL, Robbins SB, Yin M, Boivin GP, Liu Y, Greis KD, Bahassi el M, Stambrook PJ.

Mutat Res. 2011 Sep 1;714(1-2):1-10. doi: 10.1016/j.mrfmmm.2011.02.006. Epub 2011 Mar 3.


Mismatch and base excision repair proficiency in murine embryonic stem cells.

Tichy ED, Liang L, Deng L, Tischfield J, Schwemberger S, Babcock G, Stambrook PJ.

DNA Repair (Amst). 2011 Apr 3;10(4):445-51. doi: 10.1016/j.dnarep.2011.01.008. Epub 2011 Feb 18.


A human cancer-predisposing polymorphism in Cdc25A is embryonic lethal in the mouse and promotes ASK-1 mediated apoptosis.

Bahassi el M, Yin M, Robbins SB, Li YQ, Conrady DG, Yuan Z, Kovall RA, Herr AB, Stambrook PJ.

Cell Div. 2011 Feb 10;6(1):4. doi: 10.1186/1747-1028-6-4.


Preservation of genomic integrity in mouse embryonic stem cells.

Stambrook PJ, Tichy ED.

Adv Exp Med Biol. 2010;695:59-75. doi: 10.1007/978-1-4419-7037-4_5.


Mouse embryonic stem cells, but not somatic cells, predominantly use homologous recombination to repair double-strand DNA breaks.

Tichy ED, Pillai R, Deng L, Liang L, Tischfield J, Schwemberger SJ, Babcock GF, Stambrook PJ.

Stem Cells Dev. 2010 Nov;19(11):1699-711. doi: 10.1089/scd.2010.0058. Epub 2010 Aug 5.


Chk2*1100delC Acts in synergy with the Ron receptor tyrosine kinase to accelerate mammary tumorigenesis in mice.

Meyer SE, Peace BE, Bahassi el M, Kavanaugh GM, Wagh PK, Robbins SB, Yin M, Wells SI, Zinser GM, Stambrook PJ, Waltz SE.

Cancer Lett. 2010 Oct 28;296(2):186-93. doi: 10.1016/j.canlet.2010.04.011.


The novel mouse Polo-like kinase 5 responds to DNA damage and localizes in the nucleolus.

Andrysik Z, Bernstein WZ, Deng L, Myer DL, Li YQ, Tischfield JA, Stambrook PJ, Bahassi el M.

Nucleic Acids Res. 2010 May;38(9):2931-43. doi: 10.1093/nar/gkq011. Epub 2010 Jan 25.


Mice with the CHEK2*1100delC SNP are predisposed to cancer with a strong gender bias.

Bahassi el M, Robbins SB, Yin M, Boivin GP, Kuiper R, van Steeg H, Stambrook PJ.

Proc Natl Acad Sci U S A. 2009 Oct 6;106(40):17111-6. doi: 10.1073/pnas.0909237106. Epub 2009 Sep 21.


Mutation frequencies and spectra in DNA polymerase eta-deficient mice.

Busuttil RA, Lin Q, Stambrook PJ, Kucherlapati R, Vijg J.

Cancer Res. 2008 Apr 1;68(7):2081-4. doi: 10.1158/0008-5472.CAN-07-6274.


DNA repair in murine embryonic stem cells and differentiated cells.

Tichy ED, Stambrook PJ.

Exp Cell Res. 2008 Jun 10;314(9):1929-36. doi: 10.1016/j.yexcr.2008.02.007. Epub 2008 Feb 26. Review.


The checkpoint kinases Chk1 and Chk2 regulate the functional associations between hBRCA2 and Rad51 in response to DNA damage.

Bahassi EM, Ovesen JL, Riesenberg AL, Bernstein WZ, Hasty PE, Stambrook PJ.

Oncogene. 2008 Jun 26;27(28):3977-85. doi: 10.1038/onc.2008.17. Epub 2008 Mar 3.


X-rays induce distinct patterns of somatic mutation in fetal versus adult hematopoietic cells.

Liang L, Deng L, Mendonca MS, Chen Y, Zheng B, Stambrook PJ, Shao C, Tischfield JA.

DNA Repair (Amst). 2007 Sep 1;6(9):1380-5. Epub 2007 Jun 5.


The breast cancer susceptibility allele CHEK2*1100delC promotes genomic instability in a knock-in mouse model.

Bahassi el M, Penner CG, Robbins SB, Tichy E, Feliciano E, Yin M, Liang L, Deng L, Tischfield JA, Stambrook PJ.

Mutat Res. 2007 Mar 1;616(1-2):201-9. Epub 2006 Dec 15.


An ageing question: do embryonic stem cells protect their genomes?

Stambrook PJ.

Mech Ageing Dev. 2007 Jan;128(1):31-5. Epub 2006 Nov 28.


Protecting genomic integrity in somatic cells and embryonic stem cells.

Hong Y, Cervantes RB, Tichy E, Tischfield JA, Stambrook PJ.

Mutat Res. 2007 Jan 3;614(1-2):48-55. Epub 2006 Aug 17. Review.


DNA damage response and mutagenesis in mouse embryonic stem cells.

Hong Y, Cervantes RB, Stambrook PJ.

Methods Mol Biol. 2006;329:313-26.


Exposure of mice to arsenic and/or benzo[a]pyrene does not increase the frequency of Aprt-deficient cells recovered from explanted skin of Aprt heterozygous mice.

Fischer JM, Robbins SB, Kannamkumarath SS, Al-Zoughool M, Stringer SL, Talaska G, Caruso JA, Stambrook PJ, Stringer JR.

Environ Mol Mutagen. 2006 Jun;47(5):334-44.


Priming phosphorylation of Chk2 by polo-like kinase 3 (Plk3) mediates its full activation by ATM and a downstream checkpoint in response to DNA damage.

Bahassi el M, Myer DL, McKenney RJ, Hennigan RF, Stambrook PJ.

Mutat Res. 2006 Apr 11;596(1-2):166-76. Epub 2006 Feb 14.


Co-mutagenic activity of arsenic and benzo[a]pyrene in mouse skin.

Fischer JM, Robbins SB, Al-Zoughool M, Kannamkumarath SS, Stringer SL, Larson JS, Caruso JA, Talaska G, Stambrook PJ, Stringer JR.

Mutat Res. 2005 Dec 7;588(1):35-46. Epub 2005 Oct 19.


The Plk3-Cdc25 circuit.

Myer DL, Bahassi el M, Stambrook PJ.

Oncogene. 2005 Jan 10;24(2):299-305. Review.


Mlh1 mediates tissue-specific regulation of mitotic recombination.

Shao C, Deng L, Chen Y, Kucherlapati R, Stambrook PJ, Tischfield JA.

Oncogene. 2004 Dec 2;23(56):9017-24.


Accelerating drug discovery.

Kraljevic S, Stambrook PJ, Pavelic K.

EMBO Rep. 2004 Sep;5(9):837-42. No abstract available.


Restoration of an absent G1 arrest and protection from apoptosis in embryonic stem cells after ionizing radiation.

Hong Y, Stambrook PJ.

Proc Natl Acad Sci U S A. 2004 Oct 5;101(40):14443-8. Epub 2004 Sep 27.


Major histocompatibility gene therapy: the importance of haplotype and beta 2-microglobulin.

Salamone FN, Gleich LL, Li YQ, Stambrook PJ.

Laryngoscope. 2004 Apr;114(4):612-5.


Cdc25C phosphorylation on serine 191 by Plk3 promotes its nuclear translocation.

Bahassi el M, Hennigan RF, Myer DL, Stambrook PJ.

Oncogene. 2004 Apr 8;23(15):2658-63.


Impaired expression of an organic cation transporter, IMPT1, in a knockout mouse model for kidney stone disease.

Tzortzaki EG, Yang M, Glass D, Deng L, Evan AP, Bledsoe SB, Stambrook PJ, Sahota A, Tischfield JA.

Urol Res. 2003 Aug;31(4):257-61. Epub 2003 Jul 11.


Alloantigen gene therapy for head and neck cancer: evaluation of animal models.

Gleich LL, Li YQ, Li S, Gluckman JL, Stambrook PJ.

Head Neck. 2003 Apr;25(4):274-9.


Antitumor effect of secreted Flt3-ligand can act at distant tumor sites in a murine model of head and neck cancer.

Dong J, Bohinski RJ, Li YQ, Van Waes C, Hendler F, Gleich L, Stambrook PJ.

Cancer Gene Ther. 2003 Feb;10(2):96-104.


Flt-3 ligand: a potent dendritic cell stimulator and novel antitumor agent.

Dong J, McPherson CM, Stambrook PJ.

Cancer Biol Ther. 2002 Sep-Oct;1(5):486-9. Review.


Gender- and age-dependent changes in kidney androgen protein mRNA expression in a knockout mouse model for nephrolithiasis.

Tzortzaki EG, Glass D, Yang M, Evan AP, Bledsoe SB, Stambrook PJ, Sahota A, Tischfield JA.

J Histochem Cytochem. 2002 Dec;50(12):1663-9.


Induction of alpha-catenin, integrin alpha3, integrin beta6, and PDGF-B by 2,8-dihydroxyadenine crystals in cultured kidney epithelial cells.

Wang L, Raikwar N, Yang M, Deng L, McAteer JA, Stambrook PJ, Sahota A, Tischfield JA.

Exp Nephrol. 2002;10(5-6):365-73.


Mammalian Polo-like kinase 3 (Plk3) is a multifunctional protein involved in stress response pathways.

Bahassi el M, Conn CW, Myer DL, Hennigan RF, McGowan CH, Sanchez Y, Stambrook PJ.

Oncogene. 2002 Sep 26;21(43):6633-40.

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