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Items: 16


Conformational flexibility of adenine riboswitch aptamer in apo and bound states using NMR and an X-ray free electron laser.

Ding J, Swain M, Yu P, Stagno JR, Wang YX.

J Biomol NMR. 2019 Sep;73(8-9):509-518. doi: 10.1007/s10858-019-00278-w. Epub 2019 Oct 12.


Co-crystal structure of the iMango-III fluorescent RNA aptamer using an X-ray free-electron laser.

Trachman RJ 3rd, Stagno JR, Conrad C, Jones CP, Fischer P, Meents A, Wang YX, Ferré-D'Amaré AR.

Acta Crystallogr F Struct Biol Commun. 2019 Aug 1;75(Pt 8):547-551. doi: 10.1107/S2053230X19010136. Epub 2019 Aug 2.


Heavy-atom labeling of RNA by PLOR for de novo crystallographic phasing.

Stagno JR, Yu P, Dyba MA, Wang YX, Liu Y.

PLoS One. 2019 Apr 15;14(4):e0215555. doi: 10.1371/journal.pone.0215555. eCollection 2019.


Incorporation of isotopic, fluorescent, and heavy-atom-modified nucleotides into RNAs by position-selective labeling of RNA.

Liu Y, Holmstrom E, Yu P, Tan K, Zuo X, Nesbitt DJ, Sousa R, Stagno JR, Wang YX.

Nat Protoc. 2018 May;13(5):987-1005. doi: 10.1038/nprot.2018.002. Epub 2018 Apr 12.


Topological Structure Determination of RNA Using Small-Angle X-Ray Scattering.

Bhandari YR, Fan L, Fang X, Zaki GF, Stahlberg EA, Jiang W, Schwieters CD, Stagno JR, Wang YX.

J Mol Biol. 2017 Nov 24;429(23):3635-3649. doi: 10.1016/j.jmb.2017.09.006. Epub 2017 Sep 14.


Real-time crystallographic studies of the adenine riboswitch using an X-ray free-electron laser.

Stagno JR, Bhandari YR, Conrad CE, Liu Y, Wang YX.

FEBS J. 2017 Oct;284(20):3374-3380. doi: 10.1111/febs.14110. Epub 2017 Aug 1. Review.


Structures of riboswitch RNA reaction states by mix-and-inject XFEL serial crystallography.

Stagno JR, Liu Y, Bhandari YR, Conrad CE, Panja S, Swain M, Fan L, Nelson G, Li C, Wendel DR, White TA, Coe JD, Wiedorn MO, Knoska J, Oberthuer D, Tuckey RA, Yu P, Dyba M, Tarasov SG, Weierstall U, Grant TD, Schwieters CD, Zhang J, Ferré-D'Amaré AR, Fromme P, Draper DE, Liang M, Hunter MS, Boutet S, Tan K, Zuo X, Ji X, Barty A, Zatsepin NA, Chapman HN, Spence JC, Woodson SA, Wang YX.

Nature. 2017 Jan 12;541(7636):242-246. doi: 10.1038/nature20599. Epub 2016 Nov 14.


RNA Editing TUTase 1: structural foundation of substrate recognition, complex interactions and drug targeting.

Rajappa-Titu L, Suematsu T, Munoz-Tello P, Long M, Demir Ö, Cheng KJ, Stagno JR, Luecke H, Amaro RE, Aphasizheva I, Aphasizhev R, Thore S.

Nucleic Acids Res. 2016 Dec 15;44(22):10862-10878. Epub 2016 Oct 15.


Modeling RNA topological structures using small angle X-ray scattering.

Bhandari YR, Jiang W, Stahlberg EA, Stagno JR, Wang YX.

Methods. 2016 Jul 1;103:18-24. doi: 10.1016/j.ymeth.2016.04.015. Epub 2016 Jun 2. Review.


Applications of PLOR in labeling large RNAs at specific sites.

Liu Y, Yu P, Dyba M, Sousa R, Stagno JR, Wang YX.

Methods. 2016 Jul 1;103:4-10. doi: 10.1016/j.ymeth.2016.03.014. Epub 2016 Mar 23.


Synthesis and applications of RNAs with position-selective labelling and mosaic composition.

Liu Y, Holmstrom E, Zhang J, Yu P, Wang J, Dyba MA, Chen D, Ying J, Lockett S, Nesbitt DJ, Ferré-D'Amaré AR, Sousa R, Stagno JR, Wang YX.

Nature. 2015 Jun 18;522(7556):368-72. doi: 10.1038/nature14352. Epub 2015 May 4.


Small-angle X-ray scattering: a bridge between RNA secondary structures and three-dimensional topological structures.

Fang X, Stagno JR, Bhandari YR, Zuo X, Wang YX.

Curr Opin Struct Biol. 2015 Feb;30:147-160. doi: 10.1016/ Epub 2015 Mar 10. Review.


P6981, an arylstibonic acid, is a novel low nanomolar inhibitor of cAMP response element-binding protein binding to DNA.

Zhao J, Stagno JR, Varticovski L, Nimako E, Rishi V, McKinnon K, Akee R, Shoemaker RH, Ji X, Vinson C.

Mol Pharmacol. 2012 Nov;82(5):814-23. doi: 10.1124/mol.112.080820. Epub 2012 Jul 31.


Crystal structure of a plectonemic RNA supercoil.

Stagno JR, Ma B, Li J, Altieri AS, Byrd RA, Ji X.

Nat Commun. 2012 Jun 12;3:901. doi: 10.1038/ncomms1903.


Structural basis for RNA recognition by NusB and NusE in the initiation of transcription antitermination.

Stagno JR, Altieri AS, Bubunenko M, Tarasov SG, Li J, Court DL, Byrd RA, Ji X.

Nucleic Acids Res. 2011 Sep 1;39(17):7803-15. doi: 10.1093/nar/gkr418. Epub 2011 Jun 7.


Characterization of the RFX complex and the RFX5(L66A) mutant: implications for the regulation of MHC class II gene expression.

Garvie CW, Stagno JR, Reid S, Singh A, Harrington E, Boss JM.

Biochemistry. 2007 Feb 13;46(6):1597-611. Epub 2007 Jan 20.


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