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Items: 24


Feasibility of using NF1-GRD and AAV for gene replacement therapy in NF1-associated tumors.

Bai RY, Esposito D, Tam AJ, McCormick F, Riggins GJ, Wade Clapp D, Staedtke V.

Gene Ther. 2019 Jun;26(6):277-286. doi: 10.1038/s41434-019-0080-9. Epub 2019 May 24.


Disruption of a self-amplifying catecholamine loop reduces cytokine release syndrome.

Staedtke V, Bai RY, Kim K, Darvas M, Davila ML, Riggins GJ, Rothman PB, Papadopoulos N, Kinzler KW, Vogelstein B, Zhou S.

Nature. 2018 Dec;564(7735):273-277. doi: 10.1038/s41586-018-0774-y. Epub 2018 Dec 12.


MRI detection of bacterial brain abscesses and monitoring of antibiotic treatment using bacCEST.

Liu J, Bai R, Li Y, Staedtke V, Zhang S, van Zijl PCM, Liu G.

Magn Reson Med. 2018 Aug;80(2):662-671. doi: 10.1002/mrm.27180. Epub 2018 Mar 25.


Characterization of tumor vascular permeability using natural dextrans and CEST MRI.

Li Y, Qiao Y, Chen H, Bai R, Staedtke V, Han Z, Xu J, Chan KWY, Yadav N, Bulte JWM, Zhou S, van Zijl PCM, Liu G.

Magn Reson Med. 2018 Feb;79(2):1001-1009. doi: 10.1002/mrm.27014. Epub 2017 Nov 28.


Actionable molecular biomarkers in primary brain tumors.

Staedtke V, Dzaye O, Holdhoff M.

Trends Cancer. 2016 Jul;2(7):338-349. doi: 10.1016/j.trecan.2016.06.003. Review.


Prevention of tumor seeding during needle biopsy by chemotherapeutic-releasing gelatin sticks.

Bai RY, Staedtke V, Xia X, Riggins GJ.

Oncotarget. 2017 Apr 18;8(16):25955-25962. doi: 10.18632/oncotarget.15427.


Epilepsy Mechanisms in Neurocutaneous Disorders: Tuberous Sclerosis Complex, Neurofibromatosis Type 1, and Sturge-Weber Syndrome.

Stafstrom CE, Staedtke V, Comi AM.

Front Neurol. 2017 Mar 17;8:87. doi: 10.3389/fneur.2017.00087. eCollection 2017. Review.


Cancer of the Peripheral Nerve in Neurofibromatosis Type 1.

Staedtke V, Bai RY, Blakeley JO.

Neurotherapeutics. 2017 Apr;14(2):298-306. doi: 10.1007/s13311-017-0518-y. Review.


One-Component Supramolecular Filament Hydrogels as Theranostic Label-Free Magnetic Resonance Imaging Agents.

Lock LL, Li Y, Mao X, Chen H, Staedtke V, Bai R, Ma W, Lin R, Li Y, Liu G, Cui H.

ACS Nano. 2017 Jan 24;11(1):797-805. doi: 10.1021/acsnano.6b07196. Epub 2017 Jan 11.


Mebendazole and a non-steroidal anti-inflammatory combine to reduce tumor initiation in a colon cancer preclinical model.

Williamson T, Bai RY, Staedtke V, Huso D, Riggins GJ.

Oncotarget. 2016 Oct 18;7(42):68571-68584. doi: 10.18632/oncotarget.11851.


Investigational new drugs for brain cancer.

Staedtke V, Bai RY, Laterra J.

Expert Opin Investig Drugs. 2016 Aug;25(8):937-56. doi: 10.1080/13543784.2016.1182497. Epub 2016 May 17. Review.


Clostridium novyi-NT in cancer therapy.

Staedtke V, Roberts NJ, Bai RY, Zhou S.

Genes Dis. 2016 Feb 6;3(2):144-152. doi: 10.1016/j.gendis.2016.01.003. eCollection 2016 Jun. Review.


Brain Penetration and Efficacy of Different Mebendazole Polymorphs in a Mouse Brain Tumor Model.

Bai RY, Staedtke V, Wanjiku T, Rudek MA, Joshi A, Gallia GL, Riggins GJ.

Clin Cancer Res. 2015 Aug 1;21(15):3462-3470. doi: 10.1158/1078-0432.CCR-14-2681. Epub 2015 Apr 10.


Clostridium novyi-NT can cause regression of orthotopically implanted glioblastomas in rats.

Staedtke V, Bai RY, Sun W, Huang J, Kibler KK, Tyler BM, Gallia GL, Kinzler K, Vogelstein B, Zhou S, Riggins GJ.

Oncotarget. 2015 Mar 20;6(8):5536-46.


Effective treatment of diverse medulloblastoma models with mebendazole and its impact on tumor angiogenesis.

Bai RY, Staedtke V, Rudin CM, Bunz F, Riggins GJ.

Neuro Oncol. 2015 Apr;17(4):545-54. doi: 10.1093/neuonc/nou234. Epub 2014 Sep 24.


Intratumoral injection of Clostridium novyi-NT spores induces antitumor responses.

Roberts NJ, Zhang L, Janku F, Collins A, Bai RY, Staedtke V, Rusk AW, Tung D, Miller M, Roix J, Khanna KV, Murthy R, Benjamin RS, Helgason T, Szvalb AD, Bird JE, Roy-Chowdhuri S, Zhang HH, Qiao Y, Karim B, McDaniel J, Elpiner A, Sahora A, Lachowicz J, Phillips B, Turner A, Klein MK, Post G, Diaz LA Jr, Riggins GJ, Papadopoulos N, Kinzler KW, Vogelstein B, Bettegowda C, Huso DL, Varterasian M, Saha S, Zhou S.

Sci Transl Med. 2014 Aug 13;6(249):249ra111. doi: 10.1126/scitranslmed.3008982.


Podocalyxin-like protein is expressed in glioblastoma multiforme stem-like cells and is associated with poor outcome.

Binder ZA, Siu IM, Eberhart CG, Ap Rhys C, Bai RY, Staedtke V, Zhang H, Smoll NR, Piantadosi S, Piccirillo SG, Dimeco F, Weingart JD, Vescovi A, Olivi A, Riggins GJ, Gallia GL.

PLoS One. 2013 Oct 16;8(10):e75945. doi: 10.1371/journal.pone.0075945. eCollection 2013.


Noninvasive imaging of infection after treatment with tumor-homing bacteria using Chemical Exchange Saturation Transfer (CEST) MRI.

Liu G, Bettegowda C, Qiao Y, Staedtke V, Chan KW, Bai R, Li Y, Riggins GJ, Kinzler KW, Bulte JW, McMahon MT, Gilad AA, Vogelstein B, Zhou S, van Zijl PC.

Magn Reson Med. 2013 Dec;70(6):1690-8. doi: 10.1002/mrm.24955. Epub 2013 Oct 7.


OTX2 represses myogenic and neuronal differentiation in medulloblastoma cells.

Bai RY, Staedtke V, Lidov HG, Eberhart CG, Riggins GJ.

Cancer Res. 2012 Nov 15;72(22):5988-6001. doi: 10.1158/0008-5472.CAN-12-0614. Epub 2012 Sep 17.


Antiparasitic mebendazole shows survival benefit in 2 preclinical models of glioblastoma multiforme.

Bai RY, Staedtke V, Aprhys CM, Gallia GL, Riggins GJ.

Neuro Oncol. 2011 Sep;13(9):974-82. doi: 10.1093/neuonc/nor077. Epub 2011 Jul 15.


Molecular targeting of glioblastoma: Drug discovery and therapies.

Bai RY, Staedtke V, Riggins GJ.

Trends Mol Med. 2011 Jun;17(6):301-312. doi: 10.1016/j.molmed.2011.01.011. Epub 2011 Mar 14. Review.


A robust approach to enhance tumor-selective accumulation of nanoparticles.

Qiao Y, Huang X, Nimmagadda S, Bai R, Staedtke V, Foss CA, Cheong I, Holdhoff M, Kato Y, Pomper MG, Riggins GJ, Kinzler KW, Diaz LA Jr, Vogelstein B, Zhou S.

Oncotarget. 2011 Jan-Feb;2(1-2):59-68.


Evaluation of retinoic acid therapy for OTX2-positive medulloblastomas.

Bai R, Siu IM, Tyler BM, Staedtke V, Gallia GL, Riggins GJ.

Neuro Oncol. 2010 Jul;12(7):655-63. doi: 10.1093/neuonc/nop062. Epub 2010 Feb 5.


In vitro inhibition of fungal activity by macrophage-mediated sequestration and release of encapsulated amphotericin B nanosupension in red blood cells.

Staedtke V, Brähler M, Müller A, Georgieva R, Bauer S, Sternberg N, Voigt A, Lemke A, Keck C, Möschwitzer J, Bäumler H.

Small. 2010 Jan;6(1):96-103. doi: 10.1002/smll.200900919.


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