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Items: 46

1.

KLF4 is involved in the organization and regulation of pluripotency-associated three-dimensional enhancer networks.

Di Giammartino DC, Kloetgen A, Polyzos A, Liu Y, Kim D, Murphy D, Abuhashem A, Cavaliere P, Aronson B, Shah V, Dephoure N, Stadtfeld M, Tsirigos A, Apostolou E.

Nat Cell Biol. 2019 Oct;21(10):1179-1190. doi: 10.1038/s41556-019-0390-6. Epub 2019 Sep 23.

PMID:
31548608
2.

Evaluation of Stuart et al.: Distinct Molecular Trajectories Converge to Induce Naive Pluripotency.

Stadtfeld M.

Cell Stem Cell. 2019 Sep 5;25(3):297-298. doi: 10.1016/j.stem.2019.08.009.

PMID:
31491390
3.

Cellular trajectories and molecular mechanisms of iPSC reprogramming.

Apostolou E, Stadtfeld M.

Curr Opin Genet Dev. 2018 Oct;52:77-85. doi: 10.1016/j.gde.2018.06.002. Epub 2018 Jun 17. Review.

4.

Nascent Induced Pluripotent Stem Cells Efficiently Generate Entirely iPSC-Derived Mice while Expressing Differentiation-Associated Genes.

Amlani B, Liu Y, Chen T, Ee LS, Lopez P, Heguy A, Apostolou E, Kim SY, Stadtfeld M.

Cell Rep. 2018 Jan 23;22(4):876-884. doi: 10.1016/j.celrep.2017.12.098. Epub 2018 Jan 28.

5.

The TDH-GCN5L1-Fbxo15-KBP axis limits mitochondrial biogenesis in mouse embryonic stem cells.

Donato V, Bonora M, Simoneschi D, Sartini D, Kudo Y, Saraf A, Florens L, Washburn MP, Stadtfeld M, Pinton P, Pagano M.

Nat Cell Biol. 2017 Apr;19(4):341-351. doi: 10.1038/ncb3491. Epub 2017 Mar 20.

6.

Probabilistic Modeling of Reprogramming to Induced Pluripotent Stem Cells.

Liu LL, Brumbaugh J, Bar-Nur O, Smith Z, Stadtfeld M, Meissner A, Hochedlinger K, Michor F.

Cell Rep. 2016 Dec 20;17(12):3395-3406. doi: 10.1016/j.celrep.2016.11.080.

7.
8.

Regulation of transcriptional elongation in pluripotency and cell differentiation by the PHD-finger protein Phf5a.

Strikoudis A, Lazaris C, Trimarchi T, Galvao Neto AL, Yang Y, Ntziachristos P, Rothbart S, Buckley S, Dolgalev I, Stadtfeld M, Strahl BD, Dynlacht BD, Tsirigos A, Aifantis I.

Nat Cell Biol. 2016 Nov;18(11):1127-1138. doi: 10.1038/ncb3424. Epub 2016 Oct 17.

9.

Co-repressor CBFA2T2 regulates pluripotency and germline development.

Tu S, Narendra V, Yamaji M, Vidal SE, Rojas LA, Wang X, Kim SY, Garcia BA, Tuschl T, Stadtfeld M, Reinberg D.

Nature. 2016 Jun 16;534(7607):387-90. doi: 10.1038/nature18004. Epub 2016 Jun 8.

10.

The histone chaperone CAF-1 safeguards somatic cell identity.

Cheloufi S, Elling U, Hopfgartner B, Jung YL, Murn J, Ninova M, Hubmann M, Badeaux AI, Euong Ang C, Tenen D, Wesche DJ, Abazova N, Hogue M, Tasdemir N, Brumbaugh J, Rathert P, Jude J, Ferrari F, Blanco A, Fellner M, Wenzel D, Zinner M, Vidal SE, Bell O, Stadtfeld M, Chang HY, Almouzni G, Lowe SW, Rinn J, Wernig M, Aravin A, Shi Y, Park PJ, Penninger JM, Zuber J, Hochedlinger K.

Nature. 2015 Dec 10;528(7581):218-24. doi: 10.1038/nature15749.

11.

F-class cells: new routes and destinations for induced pluripotency.

Vidal SE, Stadtfeld M, Apostolou E.

Cell Stem Cell. 2015 Jan 8;16(1):9-10. doi: 10.1016/j.stem.2014.12.007.

12.

Combinatorial modulation of signaling pathways reveals cell-type-specific requirements for highly efficient and synchronous iPSC reprogramming.

Vidal SE, Amlani B, Chen T, Tsirigos A, Stadtfeld M.

Stem Cell Reports. 2014 Oct 14;3(4):574-84. doi: 10.1016/j.stemcr.2014.08.003.

13.

Histone variant H2A.X deposition pattern serves as a functional epigenetic mark for distinguishing the developmental potentials of iPSCs.

Wu T, Liu Y, Wen D, Tseng Z, Tahmasian M, Zhong M, Rafii S, Stadtfeld M, Hochedlinger K, Xiao A.

Cell Stem Cell. 2014 Sep 4;15(3):281-294. doi: 10.1016/j.stem.2014.06.004.

14.

Nucleosomal occupancy changes locally over key regulatory regions during cell differentiation and reprogramming.

West JA, Cook A, Alver BH, Stadtfeld M, Deaton AM, Hochedlinger K, Park PJ, Tolstorukov MY, Kingston RE.

Nat Commun. 2014 Aug 27;5:4719. doi: 10.1038/ncomms5719.

15.

Panning data for gold: the search for master regulators of cell fate.

Trapkov V, Stadtfeld M.

Nat Methods. 2013 Jun;10(6):476-7. doi: 10.1038/nmeth.2491. No abstract available.

PMID:
23722206
16.

Genome-wide chromatin interactions of the Nanog locus in pluripotency, differentiation, and reprogramming.

Apostolou E, Ferrari F, Walsh RM, Bar-Nur O, Stadtfeld M, Cheloufi S, Stuart HT, Polo JM, Ohsumi TK, Borowsky ML, Kharchenko PV, Park PJ, Hochedlinger K.

Cell Stem Cell. 2013 Jun 6;12(6):699-712. doi: 10.1016/j.stem.2013.04.013. Epub 2013 May 9.

17.

Homologous recombination DNA repair genes play a critical role in reprogramming to a pluripotent state.

González F, Georgieva D, Vanoli F, Shi ZD, Stadtfeld M, Ludwig T, Jasin M, Huangfu D.

Cell Rep. 2013 Mar 28;3(3):651-60. doi: 10.1016/j.celrep.2013.02.005. Epub 2013 Mar 7.

18.

A molecular roadmap of reprogramming somatic cells into iPS cells.

Polo JM, Anderssen E, Walsh RM, Schwarz BA, Nefzger CM, Lim SM, Borkent M, Apostolou E, Alaei S, Cloutier J, Bar-Nur O, Cheloufi S, Stadtfeld M, Figueroa ME, Robinton D, Natesan S, Melnick A, Zhu J, Ramaswamy S, Hochedlinger K.

Cell. 2012 Dec 21;151(7):1617-32. doi: 10.1016/j.cell.2012.11.039.

19.

Regulation of pluripotency and cellular reprogramming by the ubiquitin-proteasome system.

Buckley SM, Aranda-Orgilles B, Strikoudis A, Apostolou E, Loizou E, Moran-Crusio K, Farnsworth CL, Koller AA, Dasgupta R, Silva JC, Stadtfeld M, Hochedlinger K, Chen EI, Aifantis I.

Cell Stem Cell. 2012 Dec 7;11(6):783-98. doi: 10.1016/j.stem.2012.09.011. Epub 2012 Oct 25.

20.

Blood cell fate changes without cell cycle transition.

Stadtfeld M.

Cell Cycle. 2012 Sep 1;11(17):3154-5. doi: 10.4161/cc.21720. Epub 2012 Aug 16. No abstract available.

21.

Ascorbic acid prevents loss of Dlk1-Dio3 imprinting and facilitates generation of all-iPS cell mice from terminally differentiated B cells.

Stadtfeld M, Apostolou E, Ferrari F, Choi J, Walsh RM, Chen T, Ooi SS, Kim SY, Bestor TH, Shioda T, Park PJ, Hochedlinger K.

Nat Genet. 2012 Mar 4;44(4):398-405, S1-2. doi: 10.1038/ng.1110.

22.

Induced pluripotency: history, mechanisms, and applications.

Stadtfeld M, Hochedlinger K.

Genes Dev. 2010 Oct 15;24(20):2239-63. doi: 10.1101/gad.1963910. Review.

23.

Cell type of origin influences the molecular and functional properties of mouse induced pluripotent stem cells.

Polo JM, Liu S, Figueroa ME, Kulalert W, Eminli S, Tan KY, Apostolou E, Stadtfeld M, Li Y, Shioda T, Natesan S, Wagers AJ, Melnick A, Evans T, Hochedlinger K.

Nat Biotechnol. 2010 Aug;28(8):848-55. doi: 10.1038/nbt.1667. Epub 2010 Jul 19.

24.

Aberrant silencing of imprinted genes on chromosome 12qF1 in mouse induced pluripotent stem cells.

Stadtfeld M, Apostolou E, Akutsu H, Fukuda A, Follett P, Natesan S, Kono T, Shioda T, Hochedlinger K.

Nature. 2010 May 13;465(7295):175-81. doi: 10.1038/nature09017. Epub 2010 Apr 25.

25.

Canonical BMP signaling is dispensable for hematopoietic stem cell function in both adult and fetal liver hematopoiesis, but essential to preserve colon architecture.

Singbrant S, Karlsson G, Ehinger M, Olsson K, Jaako P, Miharada K, Stadtfeld M, Graf T, Karlsson S.

Blood. 2010 Jun 10;115(23):4689-98. doi: 10.1182/blood-2009-05-220988. Epub 2010 Apr 6.

PMID:
20371744
26.

Platelets regulate lymphatic vascular development through CLEC-2-SLP-76 signaling.

Bertozzi CC, Schmaier AA, Mericko P, Hess PR, Zou Z, Chen M, Chen CY, Xu B, Lu MM, Zhou D, Sebzda E, Santore MT, Merianos DJ, Stadtfeld M, Flake AW, Graf T, Skoda R, Maltzman JS, Koretzky GA, Kahn ML.

Blood. 2010 Jul 29;116(4):661-70. doi: 10.1182/blood-2010-02-270876. Epub 2010 Apr 2.

27.

A reprogrammable mouse strain from gene-targeted embryonic stem cells.

Stadtfeld M, Maherali N, Borkent M, Hochedlinger K.

Nat Methods. 2010 Jan;7(1):53-5. doi: 10.1038/nmeth.1409. Epub 2009 Dec 13.

28.

Differentiation stage determines potential of hematopoietic cells for reprogramming into induced pluripotent stem cells.

Eminli S, Foudi A, Stadtfeld M, Maherali N, Ahfeldt T, Mostoslavsky G, Hock H, Hochedlinger K.

Nat Genet. 2009 Sep;41(9):968-76. doi: 10.1038/ng.428. Epub 2009 Aug 9.

29.

Immortalization eliminates a roadblock during cellular reprogramming into iPS cells.

Utikal J, Polo JM, Stadtfeld M, Maherali N, Kulalert W, Walsh RM, Khalil A, Rheinwald JG, Hochedlinger K.

Nature. 2009 Aug 27;460(7259):1145-8. doi: 10.1038/nature08285. Epub 2009 Aug 9.

30.

Without a trace? PiggyBac-ing toward pluripotency.

Stadtfeld M, Hochedlinger K.

Nat Methods. 2009 May;6(5):329-30. doi: 10.1038/nmeth0509-329. No abstract available.

PMID:
19404251
31.

Induced pluripotent stem cell generation using a single lentiviral stem cell cassette.

Sommer CA, Stadtfeld M, Murphy GJ, Hochedlinger K, Kotton DN, Mostoslavsky G.

Stem Cells. 2009 Mar;27(3):543-9. doi: 10.1634/stemcells.2008-1075.

32.

Fibroblast-derived induced pluripotent stem cells show no common retroviral vector insertions.

Varas F, Stadtfeld M, de Andres-Aguayo L, Maherali N, di Tullio A, Pantano L, Notredame C, Hochedlinger K, Graf T.

Stem Cells. 2009 Feb;27(2):300-6. doi: 10.1634/stemcells.2008-0696.

33.

Heterogeneity of embryonic and adult stem cells.

Graf T, Stadtfeld M.

Cell Stem Cell. 2008 Nov 6;3(5):480-3. doi: 10.1016/j.stem.2008.10.007. Review.

34.

Induced pluripotent stem cells generated without viral integration.

Stadtfeld M, Nagaya M, Utikal J, Weir G, Hochedlinger K.

Science. 2008 Nov 7;322(5903):945-9. doi: 10.1126/science.1162494. Epub 2008 Sep 25.

35.

Reprogramming of pancreatic beta cells into induced pluripotent stem cells.

Stadtfeld M, Brennand K, Hochedlinger K.

Curr Biol. 2008 Jun 24;18(12):890-4. doi: 10.1016/j.cub.2008.05.010. Epub 2008 May 22.

36.

Defining molecular cornerstones during fibroblast to iPS cell reprogramming in mouse.

Stadtfeld M, Maherali N, Breault DT, Hochedlinger K.

Cell Stem Cell. 2008 Mar 6;2(3):230-40. doi: 10.1016/j.stem.2008.02.001. Epub 2008 Feb 14.

37.

Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution.

Maherali N, Sridharan R, Xie W, Utikal J, Eminli S, Arnold K, Stadtfeld M, Yachechko R, Tchieu J, Jaenisch R, Plath K, Hochedlinger K.

Cell Stem Cell. 2007 Jun 7;1(1):55-70. doi: 10.1016/j.stem.2007.05.014.

38.

CD41-YFP mice allow in vivo labeling of megakaryocytic cells and reveal a subset of platelets hyperreactive to thrombin stimulation.

Zhang J, Varas F, Stadtfeld M, Heck S, Faust N, Graf T.

Exp Hematol. 2007 Mar;35(3):490-499.

PMID:
17309829
39.

Klf2 is an essential regulator of vascular hemodynamic forces in vivo.

Lee JS, Yu Q, Shin JT, Sebzda E, Bertozzi C, Chen M, Mericko P, Stadtfeld M, Zhou D, Cheng L, Graf T, MacRae CA, Lepore JJ, Lo CW, Kahn ML.

Dev Cell. 2006 Dec;11(6):845-57.

40.

Reprogramming of committed T cell progenitors to macrophages and dendritic cells by C/EBP alpha and PU.1 transcription factors.

Laiosa CV, Stadtfeld M, Xie H, de Andres-Aguayo L, Graf T.

Immunity. 2006 Nov;25(5):731-44.

41.

Identification of interventricular septum precursor cells in the mouse embryo.

Stadtfeld M, Ye M, Graf T.

Dev Biol. 2007 Feb 1;302(1):195-207. Epub 2006 Sep 16.

42.

Determinants of lymphoid-myeloid lineage diversification.

Laiosa CV, Stadtfeld M, Graf T.

Annu Rev Immunol. 2006;24:705-38. Review.

PMID:
16551264
43.
44.

Fluorescent protein-cell labeling and its application in time-lapse analysis of hematopoietic differentiation.

Stadtfeld M, Varas F, Graf T.

Methods Mol Med. 2005;105:395-412. Review.

PMID:
15492410
45.

Hematopoietic stem cells expressing the myeloid lysozyme gene retain long-term, multilineage repopulation potential.

Ye M, Iwasaki H, Laiosa CV, Stadtfeld M, Xie H, Heck S, Clausen B, Akashi K, Graf T.

Immunity. 2003 Nov;19(5):689-99.

46.

[Microcomputer-assisted evaluation of intracoronary Doppler flow measurements].

Rupprecht HJ, Brennecke R, Penz P, Erbel R, Stadtfeld M, Meyer J.

Biomed Tech (Berl). 1989;34 Suppl:117-8. German. No abstract available.

PMID:
2819122

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