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Items: 1 to 50 of 160

1.

GM-CSF and CXCR4 define a T helper cell signature in multiple sclerosis.

Galli E, Hartmann FJ, Schreiner B, Ingelfinger F, Arvaniti E, Diebold M, Mrdjen D, van der Meer F, Krieg C, Nimer FA, Sanderson N, Stadelmann C, Khademi M, Piehl F, Claassen M, Derfuss T, Olsson T, Becher B.

Nat Med. 2019 Aug;25(8):1290-1300. doi: 10.1038/s41591-019-0521-4. Epub 2019 Jul 22.

PMID:
31332391
2.

Brain-resident memory T cells generated early in life predispose to autoimmune disease in mice.

Steinbach K, Vincenti I, Egervari K, Kreutzfeldt M, van der Meer F, Page N, Klimek B, Rossitto-Borlat I, Di Liberto G, Muschaweckh A, Wagner I, Hammad K, Stadelmann C, Korn T, Hartley O, Pinschewer DD, Merkler D.

Sci Transl Med. 2019 Jun 26;11(498). pii: eaav5519. doi: 10.1126/scitranslmed.aav5519.

PMID:
31243152
3.

Homozygous NMNAT2 mutation in sisters with polyneuropathy and erythromelalgia.

Huppke P, Wegener E, Gilley J, Angeletti C, Kurth I, Drenth JPH, Stadelmann C, Barrantes-Freer A, Brück W, Thiele H, Nürnberg P, Gärtner J, Orsomando G, Coleman MP.

Exp Neurol. 2019 Oct;320:112958. doi: 10.1016/j.expneurol.2019.112958. Epub 2019 May 24.

PMID:
31132363
4.

Myelin in the Central Nervous System: Structure, Function, and Pathology.

Stadelmann C, Timmler S, Barrantes-Freer A, Simons M.

Physiol Rev. 2019 Jul 1;99(3):1381-1431. doi: 10.1152/physrev.00031.2018.

PMID:
31066630
5.

Microglia damage precedes major myelin breakdown in X-linked adrenoleukodystrophy and metachromatic leukodystrophy.

Bergner CG, van der Meer F, Winkler A, Wrzos C, Türkmen M, Valizada E, Fitzner D, Hametner S, Hartmann C, Pfeifenbring S, Stoltenburg-Didinger G, Brück W, Nessler S, Stadelmann C.

Glia. 2019 Jun;67(6):1196-1209. doi: 10.1002/glia.23598. Epub 2019 Feb 11.

6.

Author Correction: Spatial and temporal heterogeneity of mouse and human microglia at single-cell resolution.

Masuda T, Sankowski R, Staszewski O, Böttcher C, Amann L, Sagar, Scheiwe C, Nessler S, Kunz P, van Loo G, Coenen VA, Reinacher PC, Michel A, Sure U, Gold R, Grün D, Priller J, Stadelmann C, Prinz M.

Nature. 2019 Apr;568(7751):E4. doi: 10.1038/s41586-019-1045-2.

PMID:
30918409
7.

Publisher Correction: β-Synuclein-reactive T cells induce autoimmune CNS grey matter degeneration.

Lodygin D, Hermann M, Schweingruber N, Flügel-Koch C, Watanabe T, Schlosser C, Merlini A, Körner H, Chang HF, Fischer HJ, Reichardt HM, Zagrebelsky M, Mollenhauer B, Kügler S, Fitzner D, Frahm J, Stadelmann C, Haberl M, Odoardi F, Flügel A.

Nature. 2019 Mar;567(7749):E15. doi: 10.1038/s41586-019-1047-0.

PMID:
30867589
8.

Laquinimod, a prototypic quinoline-3-carboxamide and aryl hydrocarbon receptor agonist, utilizes a CD155-mediated natural killer/dendritic cell interaction to suppress CNS autoimmunity.

Ott M, Avendaño-Guzmán E, Ullrich E, Dreyer C, Strauss J, Harden M, Schön M, Schön MP, Bernhardt G, Stadelmann C, Wegner C, Brück W, Nessler S.

J Neuroinflammation. 2019 Feb 26;16(1):49. doi: 10.1186/s12974-019-1437-0.

9.

Glial fibrillary acidic protein expression alters astrocytic chemokine release and protects mice from cuprizone-induced demyelination.

Kramann N, Menken L, Pförtner R, Schmid SN, Stadelmann C, Wegner C, Brück W.

Glia. 2019 Jul;67(7):1308-1319. doi: 10.1002/glia.23605. Epub 2019 Feb 23.

PMID:
30801815
10.

β-Synuclein-reactive T cells induce autoimmune CNS grey matter degeneration.

Lodygin D, Hermann M, Schweingruber N, Flügel-Koch C, Watanabe T, Schlosser C, Merlini A, Körner H, Chang HF, Fischer HJ, Reichardt HM, Zagrebelsky M, Mollenhauer B, Kügler S, Fitzner D, Frahm J, Stadelmann C, Haberl M, Odoardi F, Flügel A.

Nature. 2019 Feb;566(7745):503-508. doi: 10.1038/s41586-019-0964-2. Epub 2019 Feb 20. Erratum in: Nature. 2019 Mar;567(7749):E15.

PMID:
30787438
11.

Spatial and temporal heterogeneity of mouse and human microglia at single-cell resolution.

Masuda T, Sankowski R, Staszewski O, Böttcher C, Amann L, Sagar, Scheiwe C, Nessler S, Kunz P, van Loo G, Coenen VA, Reinacher PC, Michel A, Sure U, Gold R, Grün D, Priller J, Stadelmann C, Prinz M.

Nature. 2019 Feb;566(7744):388-392. doi: 10.1038/s41586-019-0924-x. Epub 2019 Feb 13. Erratum in: Nature. 2019 Apr;568(7751):E4.

PMID:
30760929
12.

A Randomized Trial of Endometrial Scratching before In Vitro Fertilization.

Lensen S, Osavlyuk D, Armstrong S, Stadelmann C, Hennes A, Napier E, Wilkinson J, Sadler L, Gupta D, Strandell A, Bergh C, Vigneswaran K, Teh WT, Hamoda H, Webber L, Wakeman SA, Searle L, Bhide P, McDowell S, Peeraer K, Khalaf Y, Farquhar C.

N Engl J Med. 2019 Jan 24;380(4):325-334. doi: 10.1056/NEJMoa1808737.

PMID:
30673547
13.

Association between pathological and MRI findings in multiple sclerosis.

Filippi M, Brück W, Chard D, Fazekas F, Geurts JJG, Enzinger C, Hametner S, Kuhlmann T, Preziosa P, Rovira À, Schmierer K, Stadelmann C, Rocca MA; Attendees of the Correlation between Pathological and MRI findings in MS workshop.

Lancet Neurol. 2019 Feb;18(2):198-210. doi: 10.1016/S1474-4422(18)30451-4. Review.

PMID:
30663609
14.

Incident reports versus direct observation to identify medication errors and risk factors in hospitalised newborns.

Palmero D, Di Paolo ER, Stadelmann C, Pannatier A, Sadeghipour F, Tolsa JF.

Eur J Pediatr. 2019 Feb;178(2):259-266. doi: 10.1007/s00431-018-3294-8. Epub 2018 Nov 21.

PMID:
30460407
15.

PI3K: A master regulator of brain metastasis-promoting macrophages/microglia.

Blazquez R, Wlochowitz D, Wolff A, Seitz S, Wachter A, Perera-Bel J, Bleckmann A, Beißbarth T, Salinas G, Riemenschneider MJ, Proescholdt M, Evert M, Utpatel K, Siam L, Schatlo B, Balkenhol M, Stadelmann C, Schildhaus HU, Korf U, Reinz E, Wiemann S, Vollmer E, Schulz M, Ritter U, Hanisch UK, Pukrop T.

Glia. 2018 Nov;66(11):2438-2455. doi: 10.1002/glia.23485. Epub 2018 Oct 25.

PMID:
30357946
16.

Glycoprotein NMB: a novel Alzheimer's disease associated marker expressed in a subset of activated microglia.

Hüttenrauch M, Ogorek I, Klafki H, Otto M, Stadelmann C, Weggen S, Wiltfang J, Wirths O.

Acta Neuropathol Commun. 2018 Oct 19;6(1):108. doi: 10.1186/s40478-018-0612-3.

17.

Re-evaluation of neuronal P2X7 expression using novel mouse models and a P2X7-specific nanobody.

Kaczmarek-Hajek K, Zhang J, Kopp R, Grosche A, Rissiek B, Saul A, Bruzzone S, Engel T, Jooss T, Krautloher A, Schuster S, Magnus T, Stadelmann C, Sirko S, Koch-Nolte F, Eulenburg V, Nicke A.

Elife. 2018 Aug 3;7. pii: e36217. doi: 10.7554/eLife.36217.

18.

Three-dimensional virtual histology of human cerebellum by X-ray phase-contrast tomography.

Töpperwien M, van der Meer F, Stadelmann C, Salditt T.

Proc Natl Acad Sci U S A. 2018 Jul 3;115(27):6940-6945. doi: 10.1073/pnas.1801678115. Epub 2018 Jun 18.

19.

The role of the cerebellum in multiple sclerosis-150 years after Charcot.

Parmar K, Stadelmann C, Rocca MA, Langdon D, D'Angelo E, D'Souza M, Burggraaff J, Wegner C, Sastre-Garriga J, Barrantes-Freer A, Dorn J, Uitdehaag BMJ, Montalban X, Wuerfel J, Enzinger C, Rovira A, Tintore M, Filippi M, Kappos L, Sprenger T; MAGNIMS study group.

Neurosci Biobehav Rev. 2018 Jun;89:85-98. doi: 10.1016/j.neubiorev.2018.02.012. Epub 2018 Feb 23. Review.

PMID:
29477616
20.

BCAS1 expression defines a population of early myelinating oligodendrocytes in multiple sclerosis lesions.

Fard MK, van der Meer F, Sánchez P, Cantuti-Castelvetri L, Mandad S, Jäkel S, Fornasiero EF, Schmitt S, Ehrlich M, Starost L, Kuhlmann T, Sergiou C, Schultz V, Wrzos C, Brück W, Urlaub H, Dimou L, Stadelmann C, Simons M.

Sci Transl Med. 2017 Dec 6;9(419). pii: eaam7816. doi: 10.1126/scitranslmed.aam7816.

PMID:
29212715
21.

NMDAR encephalitis: passive transfer from man to mouse by a recombinant antibody.

Malviya M, Barman S, Golombeck KS, Planagumà J, Mannara F, Strutz-Seebohm N, Wrzos C, Demir F, Baksmeier C, Steckel J, Falk KK, Gross CC, Kovac S, Bönte K, Johnen A, Wandinger KP, Martín-García E, Becker AJ, Elger CE, Klöcker N, Wiendl H, Meuth SG, Hartung HP, Seebohm G, Leypoldt F, Maldonado R, Stadelmann C, Dalmau J, Melzer N, Goebels N.

Ann Clin Transl Neurol. 2017 Oct 3;4(11):768-783. doi: 10.1002/acn3.444. eCollection 2017 Nov.

22.

[Novelties 2016 in pediatrics].

Fischer Fumeaux CJ, Fletgen Richard C, Goncalves Pereira Pinto D, Stadelmann C, Avignon V, Vial Y, Tolsa JF, Ambresin AE, Armengaud JB, Castaneda M, Coti-Bertrand P, Deppen A, Duvoisin G, Gebhard S, Holzer L, Lier F, Monney Chaubert C, Pauchard JY, Typaldou SA, Hofer M.

Rev Med Suisse. 2017 Jan 11;13(544-545):92-95. Review. French.

PMID:
28703546
23.

Acutely damaged axons are remyelinated in multiple sclerosis and experimental models of demyelination.

Schultz V, van der Meer F, Wrzos C, Scheidt U, Bahn E, Stadelmann C, Brück W, Junker A.

Glia. 2017 Aug;65(8):1350-1360. doi: 10.1002/glia.23167. Epub 2017 May 31.

24.

Targeted endomyocardial biopsy guided by real-time cardiovascular magnetic resonance.

Unterberg-Buchwald C, Ritter CO, Reupke V, Wilke RN, Stadelmann C, Steinmetz M, Schuster A, Hasenfuß G, Lotz J, Uecker M.

J Cardiovasc Magn Reson. 2017 Apr 19;19(1):45. doi: 10.1186/s12968-017-0357-3.

25.

Differential contribution of immune effector mechanisms to cortical demyelination in multiple sclerosis.

Lagumersindez-Denis N, Wrzos C, Mack M, Winkler A, van der Meer F, Reinert MC, Hollasch H, Flach A, Brühl H, Cullen E, Schlumbohm C, Fuchs E, Linington C, Barrantes-Freer A, Metz I, Wegner C, Liebetanz D, Prinz M, Brück W, Stadelmann C, Nessler S.

Acta Neuropathol. 2017 Jul;134(1):15-34. doi: 10.1007/s00401-017-1706-x. Epub 2017 Apr 6.

26.

Cerebrospinal fluid abnormalities in meningeosis neoplastica: a retrospective 12-year analysis.

Djukic M, Trimmel R, Nagel I, Spreer A, Lange P, Stadelmann C, Nau R.

Fluids Barriers CNS. 2017 Mar 28;14(1):7. doi: 10.1186/s12987-017-0057-2.

27.

New targeted approaches for the quantification of data-independent acquisition mass spectrometry.

Bruderer R, Sondermann J, Tsou CC, Barrantes-Freer A, Stadelmann C, Nesvizhskii AI, Schmidt M, Reiter L, Gomez-Varela D.

Proteomics. 2017 May;17(9). doi: 10.1002/pmic.201700021.

28.

Relationship of acute axonal damage, Wallerian degeneration, and clinical disability in multiple sclerosis.

Singh S, Dallenga T, Winkler A, Roemer S, Maruschak B, Siebert H, Brück W, Stadelmann C.

J Neuroinflammation. 2017 Mar 17;14(1):57. doi: 10.1186/s12974-017-0831-8.

29.

Diagnostic red flags: steroid-treated malignant CNS lymphoma mimicking autoimmune inflammatory demyelination.

Barrantes-Freer A, Engel AS, Rodríguez-Villagra OA, Winkler A, Bergmann M, Mawrin C, Kuempfel T, Pellkofer H, Metz I, Bleckmann A, Hernández-Durán S, Schippling S, Rushing EJ, Frank S, Glatzel M, Matschke J, Hartmann C, Reifenberger G, Müller W, Schildhaus HU, Brück W, Stadelmann C.

Brain Pathol. 2018 Mar;28(2):225-233. doi: 10.1111/bpa.12496. Epub 2017 Apr 6.

PMID:
28213912
30.

Oligodendroglial fibroblast growth factor receptor 1 gene targeting protects mice from experimental autoimmune encephalomyelitis through ERK/AKT phosphorylation.

Rajendran R, Giraldo-Velásquez M, Stadelmann C, Berghoff M.

Brain Pathol. 2018 Mar;28(2):212-224. doi: 10.1111/bpa.12487. Epub 2017 Feb 23.

PMID:
28117910
31.

Alterations of the Blood-Brain Barrier and Regional Perfusion in Tumor Development: MRI Insights from a Rat C6 Glioma Model.

Huhndorf M, Moussavi A, Kramann N, Will O, Hattermann K, Stadelmann C, Jansen O, Boretius S.

PLoS One. 2016 Dec 22;11(12):e0168174. doi: 10.1371/journal.pone.0168174. eCollection 2016.

32.

Synaptic pathology in the cerebellar dentate nucleus in chronic multiple sclerosis.

Albert M, Barrantes-Freer A, Lohrberg M, Antel JP, Prineas JW, Palkovits M, Wolff JR, Brück W, Stadelmann C.

Brain Pathol. 2017 Nov;27(6):737-747. doi: 10.1111/bpa.12450. Epub 2017 Mar 6.

PMID:
27706868
33.

T cell abundance in blood predicts acute organ toxicity in chemoradiotherapy for head and neck cancer.

Beschel LM, Leu M, Reichardt SD, Rave-Fränk M, Schirmer MA, Stadelmann C, Canis M, Wolff HA, Reichardt HM.

Oncotarget. 2016 Oct 4;7(40):65902-65915. doi: 10.18632/oncotarget.11677.

34.

MALDI imaging mass spectrometry analysis-A new approach for protein mapping in multiple sclerosis brain lesions.

Maccarrone G, Nischwitz S, Deininger SO, Hornung J, König FB, Stadelmann C, Turck CW, Weber F.

J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Mar 15;1047:131-140. doi: 10.1016/j.jchromb.2016.07.001. Epub 2016 Jul 1.

PMID:
27461358
35.

Frequency of BRAF V600E mutations in 969 central nervous system neoplasms.

Behling F, Barrantes-Freer A, Skardelly M, Nieser M, Christians A, Stockhammer F, Rohde V, Tatagiba M, Hartmann C, Stadelmann C, Schittenhelm J.

Diagn Pathol. 2016 Jun 27;11(1):55. doi: 10.1186/s13000-016-0506-2.

36.

Loss of Myelin Basic Protein Function Triggers Myelin Breakdown in Models of Demyelinating Diseases.

Weil MT, Möbius W, Winkler A, Ruhwedel T, Wrzos C, Romanelli E, Bennett JL, Enz L, Goebels N, Nave KA, Kerschensteiner M, Schaeren-Wiemers N, Stadelmann C, Simons M.

Cell Rep. 2016 Jul 12;16(2):314-322. doi: 10.1016/j.celrep.2016.06.008. Epub 2016 Jun 23.

37.

Myelin-reactive antibodies initiate T cell-mediated CNS autoimmune disease by opsonization of endogenous antigen.

Kinzel S, Lehmann-Horn K, Torke S, Häusler D, Winkler A, Stadelmann C, Payne N, Feldmann L, Saiz A, Reindl M, Lalive PH, Bernard CC, Brück W, Weber MS.

Acta Neuropathol. 2016 Jul;132(1):43-58. doi: 10.1007/s00401-016-1559-8. Epub 2016 Mar 29.

38.

Late-onset leukoencephalopathy with cerebral calcifications and cysts: case report and review of the literature.

Stephani C, Pfeifenbring S, Mohr A, Stadelmann C.

BMC Neurol. 2016 Feb 6;16:19. doi: 10.1186/s12883-016-0543-1. Review.

39.

Pivotal Role for CD16+ Monocytes in Immune Surveillance of the Central Nervous System.

Waschbisch A, Schröder S, Schraudner D, Sammet L, Weksler B, Melms A, Pfeifenbring S, Stadelmann C, Schwab S, Linker RA.

J Immunol. 2016 Feb 15;196(4):1558-67. doi: 10.4049/jimmunol.1501960. Epub 2016 Jan 8.

40.

CD14 is a key organizer of microglial responses to CNS infection and injury.

Janova H, Böttcher C, Holtman IR, Regen T, van Rossum D, Götz A, Ernst AS, Fritsche C, Gertig U, Saiepour N, Gronke K, Wrzos C, Ribes S, Rolfes S, Weinstein J, Ehrenreich H, Pukrop T, Kopatz J, Stadelmann C, Salinas-Riester G, Weber MS, Prinz M, Brück W, Eggen BJ, Boddeke HW, Priller J, Hanisch UK.

Glia. 2016 Apr;64(4):635-49. doi: 10.1002/glia.22955. Epub 2015 Dec 18.

PMID:
26683584
41.

Mutation Profiling of Lung Cancers with Long-Term Response to Gefitinib Therapy.

Gautschi O, Stadelmann C, Aebersold-Keller F, König K, Büttner R, Heukamp LC, Betticher D, Baumann C, Buser K, Calderoni A, Casty A, DʼAddario G, Irlé C, Mamot C, Morant R, Trojan A, Pellicioli E, Jehle-Schwertfeger S, Aebi S, Diebold J.

Oncol Res Treat. 2015;38(11):560-9. doi: 10.1159/000441367. Epub 2015 Oct 21.

PMID:
26599269
42.

Extensive brain demyelinating lesions under natalizumab: The role of anti-natalizumab antibodies.

Debs R, Maillart E, Fahed R, Papeix C, Duyckaerts C, Stadelmann C, Galanaud D, Lubetzki C.

Neurology. 2015 Nov 3;85(18):1630-2. doi: 10.1212/WNL.0000000000002084. Epub 2015 Oct 9. No abstract available.

PMID:
26453649
43.

Evaluation of Study and Patient Characteristics of Clinical Studies in Primary Progressive Multiple Sclerosis: A Systematic Review.

Ziemssen T, Rauer S, Stadelmann C, Henze T, Koehler J, Penner IK, Lang M, Poehlau D, Baier-Ebert M, Schieb H, Meuth S.

PLoS One. 2015 Sep 22;10(9):e0138243. doi: 10.1371/journal.pone.0138243. eCollection 2015. Review.

44.

The metastatic infiltration at the metastasis/brain parenchyma-interface is very heterogeneous and has a significant impact on survival in a prospective study.

Siam L, Bleckmann A, Chaung HN, Mohr A, Klemm F, Barrantes-Freer A, Blazquez R, Wolff HA, Lüke F, Rohde V, Stadelmann C, Pukrop T.

Oncotarget. 2015 Oct 6;6(30):29254-67. doi: 10.18632/oncotarget.4201.

45.

Remyelination After Cuprizone-Induced Demyelination Is Accelerated in Juvenile Mice.

Pfeifenbring S, Nessler S, Wegner C, Stadelmann C, Brück W.

J Neuropathol Exp Neurol. 2015 Aug;74(8):756-66. doi: 10.1097/NEN.0000000000000214.

PMID:
26115190
46.

B lymphocytes in neuromyelitis optica.

Bennett JL, O'Connor KC, Bar-Or A, Zamvil SS, Hemmer B, Tedder TF, von Büdingen HC, Stuve O, Yeaman MR, Smith TJ, Stadelmann C.

Neurol Neuroimmunol Neuroinflamm. 2015 May 7;2(3):e104. doi: 10.1212/NXI.0000000000000104. eCollection 2015 Jun. Review.

47.

Fibroblast growth factor signalling in multiple sclerosis: inhibition of myelination and induction of pro-inflammatory environment by FGF9.

Lindner M, Thümmler K, Arthur A, Brunner S, Elliott C, McElroy D, Mohan H, Williams A, Edgar JM, Schuh C, Stadelmann C, Barnett SC, Lassmann H, Mücklisch S, Mudaliar M, Schaeren-Wiemers N, Meinl E, Linington C.

Brain. 2015 Jul;138(Pt 7):1875-93. doi: 10.1093/brain/awv102. Epub 2015 Apr 22.

48.

Transcript profiling of different types of multiple sclerosis lesions yields FGF1 as a promoter of remyelination.

Mohan H, Friese A, Albrecht S, Krumbholz M, Elliott CL, Arthur A, Menon R, Farina C, Junker A, Stadelmann C, Barnett SC, Huitinga I, Wekerle H, Hohlfeld R, Lassmann H, Kuhlmann T, Linington C, Meinl E.

Acta Neuropathol Commun. 2014 Dec 11;2:168. doi: 10.1186/s40478-014-0168-9.

49.

The intrinsic pathogenic role of autoantibodies to aquaporin 4 mediating spinal cord disease in a rat passive-transfer model.

Geis C, Ritter C, Ruschil C, Weishaupt A, Grünewald B, Stoll G, Holmoy T, Misu T, Fujihara K, Hemmer B, Stadelmann C, Bennett JL, Sommer C, Toyka KV.

Exp Neurol. 2015 Mar;265:8-21. doi: 10.1016/j.expneurol.2014.12.015. Epub 2014 Dec 24.

50.

Intrathecal anti-CD20 efficiently depletes meningeal B cells in CNS autoimmunity.

Lehmann-Horn K, Kinzel S, Feldmann L, Radelfahr F, Hemmer B, Traffehn S, Bernard CC, Stadelmann C, Brück W, Weber MS.

Ann Clin Transl Neurol. 2014 Jul;1(7):490-6. doi: 10.1002/acn3.71. Epub 2014 Jul 3.

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