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Items: 1 to 50 of 87

1.

Human urotensin-II is a potent vasoconstrictor and agonist for the orphan receptor GPR14.

Ames RS, Sarau HM, Chambers JK, Willette RN, Aiyar NV, Romanic AM, Louden CS, Foley JJ, Sauermelch CF, Coatney RW, Ao Z, Disa J, Holmes SD, Stadel JM, Martin JD, Liu WS, Glover GI, Wilson S, McNulty DE, Ellis CE, Elshourbagy NA, Shabon U, Trill JJ, Hay DW, Ohlstein EH, Bergsma DJ, Douglas SA.

Nature. 1999 Sep 16;401(6750):282-6. Erratum in: Nature 1999 Dec 23-30;402(6764):898.

PMID:
10499587
2.
4.

In vitro and in vivo characterization of intrinsic sympathomimetic activity in normal and heart failure rats.

Willette RN, Aiyar N, Yue TL, Mitchell MP, Disa J, Storer BL, Naselsky DP, Stadel JM, Ohlstein EH, Ruffolo RR Jr.

J Pharmacol Exp Ther. 1999 Apr;289(1):48-53.

PMID:
10086986
5.

Orphan G-protein-coupled receptors: the next generation of drug targets?

Wilson S, Bergsma DJ, Chambers JK, Muir AI, Fantom KG, Ellis C, Murdock PR, Herrity NC, Stadel JM.

Br J Pharmacol. 1998 Dec;125(7):1387-92. Review.

6.

Evidence for multiple, biochemically distinguishable states in the G protein-coupled receptor, rhodopsin.

Surya A, Stadel JM, Knox BE.

Trends Pharmacol Sci. 1998 Jul;19(7):243-7. Review. No abstract available.

PMID:
9703752
7.

Molecular cloning of a novel chemokine receptor-like gene from early stage chick embryos.

Gupta SK, Pillarisetti K, Gray SL, Stadel JM.

Biochem Mol Biol Int. 1998 Apr;44(4):673-81.

PMID:
9584981
8.

Binding of [3H]-SK&F 107260 and [3H]-SB 214857 to purified integrin alphaIIbbeta3: evidence for a common binding site for cyclic arginyl-glycinyl-aspartic acid peptides and nonpeptides.

Wong A, Hwang SM, Johanson K, Samanen J, Bennett D, Landvatter SW, Chen W, Heys JR, Ali FE, Ku TW, Bondinell W, Nichols AJ, Powers DA, Stadel JM.

J Pharmacol Exp Ther. 1998 Apr;285(1):228-35.

PMID:
9536015
9.

Chemokine receptors in human endothelial cells. Functional expression of CXCR4 and its transcriptional regulation by inflammatory cytokines.

Gupta SK, Lysko PG, Pillarisetti K, Ohlstein E, Stadel JM.

J Biol Chem. 1998 Feb 13;273(7):4282-7.

10.

Orphan G protein-coupled receptors: a neglected opportunity for pioneer drug discovery.

Stadel JM, Wilson S, Bergsma DJ.

Trends Pharmacol Sci. 1997 Nov;18(11):430-7. Review.

PMID:
9426471
11.

Mechanisms of adaptive supersensitivity: correlation of guinea pig atrial supersensitivity with modifications in adenylyl cyclase activity.

Roberts MI, Stadel JM, Torphy TJ, Fleming WW, Taylor DA.

Biochem Pharmacol. 1997 Feb 7;53(3):347-56.

PMID:
9065738
12.

Osteopontin expression in platelet-derived growth factor-stimulated vascular smooth muscle cells and carotid artery after balloon angioplasty.

Wang X, Louden C, Ohlstein EH, Stadel JM, Gu JL, Yue TL.

Arterioscler Thromb Vasc Biol. 1996 Nov;16(11):1365-72.

PMID:
8911275
13.
14.

Studies on alpha v beta 3/ligand interactions using a [3H]SK&F-107260 binding assay.

Wong A, Hwang SM, McDevitt P, McNulty D, Stadel JM, Johanson K.

Mol Pharmacol. 1996 Sep;50(3):529-37.

PMID:
8794891
15.
16.

Lysine 182 of endothelin B receptor modulates agonist selectivity and antagonist affinity: evidence for the overlap of peptide and non-peptide ligand binding sites.

Lee JA, Brinkmann JA, Longton ED, Peishoff CE, Lago MA, Leber JD, Cousins RD, Gao A, Stadel JM, Kumar CS, et al.

Biochemistry. 1994 Dec 6;33(48):14543-9.

PMID:
7981216
17.

Characterization of mammalian Gs-alpha proteins expressed in yeast.

Stadel JM, Ecker DJ, Powers DA, Marsh J, Hoyle K, Gross M, Minnich MD, Butt TR, Crooke ST.

J Recept Res. 1994 Dec;14(6-8):357-79.

PMID:
7877135
18.

Osteopontin-stimulated vascular smooth muscle cell migration is mediated by beta 3 integrin.

Yue TL, McKenna PJ, Ohlstein EH, Farach-Carson MC, Butler WT, Johanson K, McDevitt P, Feuerstein GZ, Stadel JM.

Exp Cell Res. 1994 Oct;214(2):459-64.

PMID:
7925641
19.

Analogues of the thrombin receptor tethered-ligand enhance mesangial cell proliferation.

Albrightson CR, Zabko-Potapovich B, Dytko G, Bryan WM, Hoyle K, Moore ML, Stadel JM.

Cell Signal. 1994 Sep;6(7):743-50.

PMID:
7888301
20.

Tyr-129 is important to the peptide ligand affinity and selectivity of human endothelin type A receptor.

Lee JA, Elliott JD, Sutiphong JA, Friesen WJ, Ohlstein EH, Stadel JM, Gleason JG, Peishoff CE.

Proc Natl Acad Sci U S A. 1994 Jul 19;91(15):7164-8.

21.

Characterization of phospholipase A2 from human nasal lavage.

Stadel JM, Hoyle K, Naclerio RM, Roshak A, Chilton FH.

Am J Respir Cell Mol Biol. 1994 Jul;11(1):108-13.

PMID:
8018333
22.

Alpha-adrenoceptors: recent developments.

Ruffolo RR Jr, Stadel JM, Hieble JP.

Med Res Rev. 1994 Mar;14(2):229-70. Review. No abstract available.

PMID:
7910646
23.

Changes in the structure and function of the human thrombin receptor during receptor activation, internalization, and recycling.

Brass LF, Pizarro S, Ahuja M, Belmonte E, Blanchard N, Stadel JM, Hoxie JA.

J Biol Chem. 1994 Jan 28;269(4):2943-52.

24.

Modulation of vitronectin receptor-mediated osteoclast adhesion by Arg-Gly-Asp peptide analogs: a structure-function analysis.

Horton MA, Dorey EL, Nesbitt SA, Samanen J, Ali FE, Stadel JM, Nichols A, Greig R, Helfrich MH.

J Bone Miner Res. 1993 Feb;8(2):239-47.

PMID:
7680185
25.

Pharmacologic and therapeutic applications of alpha 2-adrenoceptor subtypes.

Ruffolo RR Jr, Nichols AJ, Stadel JM, Hieble JP.

Annu Rev Pharmacol Toxicol. 1993;33:243-79. Review. No abstract available.

PMID:
8098595
26.

Recombinant human secretory phospholipase A2: purification and characterization of the enzyme for active site studies.

Stadel JM, Jones C, Livi GP, Hoyle K, Kurdyla J, Roshak A, McLaughlin MM, Pfarr DA, Comer S, Strickler J, et al.

J Mol Recognit. 1992 Dec;5(4):145-53.

PMID:
1339483
27.

Adenylyl cyclase and guanine nucleotide-binding proteins in supersensitive guinea pig ventricles.

Roberts MI, Biser PS, Stadel JM, Taylor DA, Fleming WW.

Mol Pharmacol. 1992 Nov;42(5):784-91.

PMID:
1331761
28.

Cloning and characterization of a human angiotensin II type 1 receptor.

Bergsma DJ, Ellis C, Kumar C, Nuthulaganti P, Kersten H, Elshourbagy N, Griffin E, Stadel JM, Aiyar N.

Biochem Biophys Res Commun. 1992 Mar 31;183(3):989-95.

PMID:
1567413
29.

Down-regulation of beta-adrenergic receptors by pindolol in Gs alpha-transfected S49 cyc- murine lymphoma cells.

Gonzales JM, O'Donnell JK, Stadel JM, Sweet RW, Molinoff PB.

J Neurochem. 1992 Mar;58(3):1093-1103.

PMID:
1310718
30.
31.

Coexpression of human cAMP-specific phosphodiesterase activity and high affinity rolipram binding in yeast.

Torphy TJ, Stadel JM, Burman M, Cieslinski LB, McLaughlin MM, White JR, Livi GP.

J Biol Chem. 1992 Jan 25;267(3):1798-804.

32.

Structure and function of alpha-adrenoceptors.

Ruffolo RR Jr, Nichols AJ, Stadel JM, Hieble JP.

Pharmacol Rev. 1991 Dec;43(4):475-505. Review. No abstract available.

PMID:
1685567
33.

Expression and characterization of the long and short splice variants of GS alpha in S49 cyc- cells.

O'Donnell JK, Sweet RW, Stadel JM.

Mol Pharmacol. 1991 Jun;39(6):702-10.

PMID:
1646945
34.
35.

Tumor necrosis factor-mediated biological activities involve a G-protein-dependent mechanism.

Earl CQ, Stadel JM, Anzano MA.

J Biol Response Mod. 1990 Aug;9(4):361-7.

PMID:
2168471
36.
37.
38.

Genetic regulation of beta 2-adrenergic receptors in 3T3-L1 fibroblasts.

Nakada MT, Haskell KM, Ecker DJ, Stadel JM, Crooke ST.

Biochem J. 1989 May 15;260(1):53-9.

39.

Increasing gene expression in yeast by fusion to ubiquitin.

Ecker DJ, Stadel JM, Butt TR, Marsh JA, Monia BP, Powers DA, Gorman JA, Clark PE, Warren F, Shatzman A, et al.

J Biol Chem. 1989 May 5;264(13):7715-9.

41.

Ubiquitin fusion augments the yield of cloned gene products in Escherichia coli.

Butt TR, Jonnalagadda S, Monia BP, Sternberg EJ, Marsh JA, Stadel JM, Ecker DJ, Crooke ST.

Proc Natl Acad Sci U S A. 1989 Apr;86(8):2540-4.

42.

Fluoride interaction with G-proteins.

Stadel JM, Crooke ST.

Biochem J. 1989 Mar 15;258(3):932-3. No abstract available.

43.

Immunochemical comparison of pertussis toxin substrates in brain and peripheral tissues.

Kanaho Y, Katada T, Hoyle K, Crooke ST, Stadel JM.

Cell Signal. 1989;1(6):553-60.

PMID:
2518356
46.

Coupling of TGF-beta-induced mitogenesis to G-protein activation in AKR-2B cells.

Murthy US, Anzano MA, Stadel JM, Greig R.

Biochem Biophys Res Commun. 1988 May 16;152(3):1228-35.

PMID:
3132155
48.

Tumorigenicity of the cyc- variant of the S49 murine lymphoma deficient in the Gs-alpha subunit of adenylate cyclase.

Stadel JM, Johnson RK, Mirabelli CK, Powers DA, Sung CM, Faucette LF, McCabe FL, Crooke ST.

Cancer Res. 1988 Feb 1;48(3):641-4.

49.

Regulation of beta-adrenoceptor number and subtype in 3T3-L1 preadipocytes by sodium butyrate.

Stadel JM, Poksay KS, Nakada MT, Crooke ST.

Eur J Pharmacol. 1987 Nov 3;143(1):35-44.

PMID:
2826186

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