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Items: 37

1.

Evaluation of α-hydroxycinnamic acids as pyruvate carboxylase inhibitors.

Burkett DJ, Wyatt BN, Mews M, Bautista A, Engel R, Dockendorff C, Donaldson WA, St Maurice M.

Bioorg Med Chem. 2019 Sep 15;27(18):4041-4047. doi: 10.1016/j.bmc.2019.07.027. Epub 2019 Jul 15.

PMID:
31351848
2.

A high-throughput screening assay for pyruvate carboxylase.

Wyatt BN, Arnold LA, St Maurice M.

Anal Biochem. 2018 Jun 1;550:90-98. doi: 10.1016/j.ab.2018.04.012. Epub 2018 Apr 12.

PMID:
29655770
3.

Allosteric regulation alters carrier domain translocation in pyruvate carboxylase.

Liu Y, Budelier MM, Stine K, St Maurice M.

Nat Commun. 2018 Apr 11;9(1):1384. doi: 10.1038/s41467-018-03814-8.

4.

A Paradigm for CH Bond Cleavage: Structural and Functional Aspects of Transition State Stabilization by Mandelate Racemase.

Bearne SL, St Maurice M.

Adv Protein Chem Struct Biol. 2017;109:113-160. doi: 10.1016/bs.apcsb.2017.04.007. Epub 2017 Jun 9. Review.

PMID:
28683916
5.

The urea carboxylase and allophanate hydrolase activities of urea amidolyase are functionally independent.

Lin Y, Boese CJ, St Maurice M.

Protein Sci. 2016 Oct;25(10):1812-24. doi: 10.1002/pro.2990. Epub 2016 Aug 5.

6.

Writing Assignments with a Metacognitive Component Enhance Learning in a Large Introductory Biology Course.

Mynlieff M, Manogaran AL, St Maurice M, Eddinger TJ.

CBE Life Sci Educ. 2014 Summer;13(2):311-21. doi: 10.1187/cbe.13-05-0097.

7.

Inactivation of Mandelate Racemase by 3-Hydroxypyruvate Reveals a Potential Mechanistic Link between Enzyme Superfamilies.

Nagar M, Wyatt BN, St Maurice M, Bearne SL.

Biochemistry. 2015 May 5;54(17):2747-57. doi: 10.1021/acs.biochem.5b00221. Epub 2015 Apr 20.

PMID:
25844917
8.

The role of biotin and oxamate in the carboxyltransferase reaction of pyruvate carboxylase.

Lietzan AD, Lin Y, St Maurice M.

Arch Biochem Biophys. 2014 Nov 15;562:70-9. doi: 10.1016/j.abb.2014.08.008. Epub 2014 Aug 23.

9.

Potent inhibition of mandelate racemase by a fluorinated substrate-product analogue with a novel binding mode.

Nagar M, Lietzan AD, St Maurice M, Bearne SL.

Biochemistry. 2014 Feb 25;53(7):1169-78. doi: 10.1021/bi401703h. Epub 2014 Feb 10.

PMID:
24472022
10.

Functionally diverse biotin-dependent enzymes with oxaloacetate decarboxylase activity.

Lietzan AD, St Maurice M.

Arch Biochem Biophys. 2014 Feb 15;544:75-86. doi: 10.1016/j.abb.2013.10.014. Epub 2013 Oct 30. Review.

PMID:
24184447
11.

Insights into the carboxyltransferase reaction of pyruvate carboxylase from the structures of bound product and intermediate analogs.

Lietzan AD, St Maurice M.

Biochem Biophys Res Commun. 2013 Nov 15;441(2):377-82. doi: 10.1016/j.bbrc.2013.10.066. Epub 2013 Oct 22.

12.

A substrate-induced biotin binding pocket in the carboxyltransferase domain of pyruvate carboxylase.

Lietzan AD, St Maurice M.

J Biol Chem. 2013 Jul 5;288(27):19915-25. doi: 10.1074/jbc.M113.477828. Epub 2013 May 22.

13.
14.

A flagellar A-kinase anchoring protein with two amphipathic helices forms a structural scaffold in the radial spoke complex.

Sivadas P, Dienes JM, St Maurice M, Meek WD, Yang P.

J Cell Biol. 2012 Nov 12;199(4):639-51. doi: 10.1083/jcb.201111042.

15.

Roles of Arg427 and Arg472 in the binding and allosteric effects of acetyl CoA in pyruvate carboxylase.

Adina-Zada A, Sereeruk C, Jitrapakdee S, Zeczycki TN, St Maurice M, Cleland WW, Wallace JC, Attwood PV.

Biochemistry. 2012 Oct 16;51(41):8208-17. doi: 10.1021/bi301060d. Epub 2012 Oct 2.

16.

The enzymes of biotin dependent CO₂ metabolism: what structures reveal about their reaction mechanisms.

Waldrop GL, Holden HM, St Maurice M.

Protein Sci. 2012 Nov;21(11):1597-619. doi: 10.1002/pro.2156. Review.

17.

Allosteric regulation of the biotin-dependent enzyme pyruvate carboxylase by acetyl-CoA.

Adina-Zada A, Zeczycki TN, St Maurice M, Jitrapakdee S, Cleland WW, Attwood PV.

Biochem Soc Trans. 2012 Jun 1;40(3):567-72. doi: 10.1042/BST20120041. Review.

PMID:
22616868
18.

Structure of mandelate racemase with bound intermediate analogues benzohydroxamate and cupferron.

Lietzan AD, Nagar M, Pellmann EA, Bourque JR, Bearne SL, St Maurice M.

Biochemistry. 2012 Feb 14;51(6):1160-70. doi: 10.1021/bi2018514. Epub 2012 Feb 3.

19.

Activation and inhibition of pyruvate carboxylase from Rhizobium etli.

Zeczycki TN, Menefee AL, Jitrapakdee S, Wallace JC, Attwood PV, St Maurice M, Cleland WW.

Biochemistry. 2011 Nov 15;50(45):9694-707. doi: 10.1021/bi201276r. Epub 2011 Oct 14.

20.

Interaction between the biotin carboxyl carrier domain and the biotin carboxylase domain in pyruvate carboxylase from Rhizobium etli.

Lietzan AD, Menefee AL, Zeczycki TN, Kumar S, Attwood PV, Wallace JC, Cleland WW, St Maurice M.

Biochemistry. 2011 Nov 15;50(45):9708-23. doi: 10.1021/bi201277j. Epub 2011 Oct 18.

21.

Novel insights into the biotin carboxylase domain reactions of pyruvate carboxylase from Rhizobium etli.

Zeczycki TN, Menefee AL, Adina-Zada A, Jitrapakdee S, Surinya KH, Wallace JC, Attwood PV, St Maurice M, Cleland WW.

Biochemistry. 2011 Nov 15;50(45):9724-37. doi: 10.1021/bi2012788. Epub 2011 Oct 13.

22.

Probing the allosteric activation of pyruvate carboxylase using 2',3'-O-(2,4,6-trinitrophenyl) adenosine 5'-triphosphate as a fluorescent mimic of the allosteric activator acetyl CoA.

Adina-Zada A, Hazra R, Sereeruk C, Jitrapakdee S, Zeczycki TN, St Maurice M, Cleland WW, Wallace JC, Attwood PV.

Arch Biochem Biophys. 2011 May 15;509(2):117-26. doi: 10.1016/j.abb.2011.03.006. Epub 2011 Mar 21.

23.

Probing the catalytic roles of Arg548 and Gln552 in the carboxyl transferase domain of the Rhizobium etli pyruvate carboxylase by site-directed mutagenesis.

Duangpan S, Jitrapakdee S, Adina-Zada A, Byrne L, Zeczycki TN, St Maurice M, Cleland WW, Wallace JC, Attwood PV.

Biochemistry. 2010 Apr 20;49(15):3296-304. doi: 10.1021/bi901894t.

24.

Insight into the carboxyl transferase domain mechanism of pyruvate carboxylase from Rhizobium etli.

Zeczycki TN, St Maurice M, Jitrapakdee S, Wallace JC, Attwood PV, Cleland WW.

Biochemistry. 2009 May 26;48(20):4305-13. doi: 10.1021/bi9003759.

26.

Structure, mechanism and regulation of pyruvate carboxylase.

Jitrapakdee S, St Maurice M, Rayment I, Cleland WW, Wallace JC, Attwood PV.

Biochem J. 2008 Aug 1;413(3):369-87. doi: 10.1042/BJ20080709. Review.

27.

Structural characterization of a human-type corrinoid adenosyltransferase confirms that coenzyme B12 is synthesized through a four-coordinate intermediate.

St Maurice M, Mera P, Park K, Brunold TC, Escalante-Semerena JC, Rayment I.

Biochemistry. 2008 May 27;47(21):5755-66. doi: 10.1021/bi800132d. Epub 2008 May 2.

28.

Structural and functional analyses of the human-type corrinoid adenosyltransferase (PduO) from Lactobacillus reuteri.

Mera PE, St Maurice M, Rayment I, Escalante-Semerena JC.

Biochemistry. 2007 Dec 4;46(48):13829-36. Epub 2007 Nov 8.

PMID:
17988155
29.

Domain architecture of pyruvate carboxylase, a biotin-dependent multifunctional enzyme.

St Maurice M, Reinhardt L, Surinya KH, Attwood PV, Wallace JC, Cleland WW, Rayment I.

Science. 2007 Aug 24;317(5841):1076-9.

30.
31.

Structural characterization of the active site of the PduO-type ATP:Co(I)rrinoid adenosyltransferase from Lactobacillus reuteri.

St Maurice M, Mera PE, Taranto MP, Sesma F, Escalante-Semerena JC, Rayment I.

J Biol Chem. 2007 Jan 26;282(4):2596-605. Epub 2006 Nov 22.

32.

Perturbing the hydrophobic pocket of mandelate racemase to probe phenyl motion during catalysis.

Siddiqi F, Bourque JR, Jiang H, Gardner M, St Maurice M, Blouin C, Bearne SL.

Biochemistry. 2005 Jun 28;44(25):9013-21.

PMID:
15966725
33.

Hydrophobic nature of the active site of mandelate racemase.

St Maurice M, Bearne SL.

Biochemistry. 2004 Mar 9;43(9):2524-32.

PMID:
14992589
34.

Inhibition of mandelate racemase by alpha-fluorobenzylphosphonates.

St Maurice M, Bearne SL, Lu W, Taylor SD.

Bioorg Med Chem Lett. 2003 Jun 16;13(12):2041-4.

PMID:
12781191
35.

Kinetics and thermodynamics of mandelate racemase catalysis.

St Maurice M, Bearne SL.

Biochemistry. 2002 Mar 26;41(12):4048-58.

PMID:
11900548
37.

An assay for mandelate racemase using high-performance liquid chromatography.

Bearne SL, St Maurice M, Vaughan MD.

Anal Biochem. 1999 May 1;269(2):332-6.

PMID:
10222006

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