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Items: 12


Stem cell-derived clade F AAVs mediate high-efficiency homologous recombination-based genome editing.

Smith LJ, Wright J, Clark G, Ul-Hasan T, Jin X, Fong A, Chandra M, St Martin T, Rubin H, Knowlton D, Ellsworth JL, Fong Y, Wong KK Jr, Chatterjee S.

Proc Natl Acad Sci U S A. 2018 Jul 31;115(31):E7379-E7388. doi: 10.1073/pnas.1802343115. Epub 2018 Jul 17. Erratum in: Proc Natl Acad Sci U S A. 2019 Jan 2;116(1):337.


Discovery of a mutant-selective covalent inhibitor of EGFR that overcomes T790M-mediated resistance in NSCLC.

Walter AO, Sjin RT, Haringsma HJ, Ohashi K, Sun J, Lee K, Dubrovskiy A, Labenski M, Zhu Z, Wang Z, Sheets M, St Martin T, Karp R, van Kalken D, Chaturvedi P, Niu D, Nacht M, Petter RC, Westlin W, Lin K, Jaw-Tsai S, Raponi M, Van Dyke T, Etter J, Weaver Z, Pao W, Singh J, Simmons AD, Harding TC, Allen A.

Cancer Discov. 2013 Dec;3(12):1404-15. doi: 10.1158/2159-8290.CD-13-0314. Epub 2013 Sep 24.


Discovery of a potent and isoform-selective targeted covalent inhibitor of the lipid kinase PI3Kα.

Nacht M, Qiao L, Sheets MP, St Martin T, Labenski M, Mazdiyasni H, Karp R, Zhu Z, Chaturvedi P, Bhavsar D, Niu D, Westlin W, Petter RC, Medikonda AP, Singh J.

J Med Chem. 2013 Feb 14;56(3):712-21. doi: 10.1021/jm3008745. Epub 2013 Feb 5.


Tumor endothelial marker 7 (TEM-7): a novel target for antiangiogenic therapy.

Bagley RG, Rouleau C, Weber W, Mehraein K, Smale R, Curiel M, Callahan M, Roy A, Boutin P, St Martin T, Nacht M, Teicher BA.

Microvasc Res. 2011 Nov;82(3):253-62. doi: 10.1016/j.mvr.2011.09.004. Epub 2011 Sep 17.


Selective irreversible inhibition of a protease by targeting a noncatalytic cysteine.

Hagel M, Niu D, St Martin T, Sheets MP, Qiao L, Bernard H, Karp RM, Zhu Z, Labenski MT, Chaturvedi P, Nacht M, Westlin WF, Petter RC, Singh J.

Nat Chem Biol. 2011 Jan;7(1):22-4. doi: 10.1038/nchembio.492. Epub 2010 Nov 28.


Netrin-4 regulates angiogenic responses and tumor cell growth.

Nacht M, St Martin TB, Byrne A, Klinger KW, Teicher BA, Madden SL, Jiang Y.

Exp Cell Res. 2009 Mar 10;315(5):784-94. doi: 10.1016/j.yexcr.2008.11.018. Epub 2008 Dec 6.


Human endothelial precursor cells express tumor endothelial marker 1/endosialin/CD248.

Bagley RG, Rouleau C, St Martin T, Boutin P, Weber W, Ruzek M, Honma N, Nacht M, Shankara S, Kataoka S, Ishida I, Roberts BL, Teicher BA.

Mol Cancer Ther. 2008 Aug;7(8):2536-46. doi: 10.1158/1535-7163.MCT-08-0050.


Protein tyrosine phosphatase PRL-3 in malignant cells and endothelial cells: expression and function.

Rouleau C, Roy A, St Martin T, Dufault MR, Boutin P, Liu D, Zhang M, Puorro-Radzwill K, Rulli L, Reczek D, Bagley R, Byrne A, Weber W, Roberts B, Klinger K, Brondyk W, Nacht M, Madden S, Burrier R, Shankara S, Teicher BA.

Mol Cancer Ther. 2006 Feb;5(2):219-29.


Alterations in vascular gene expression in invasive breast carcinoma.

Parker BS, Argani P, Cook BP, Liangfeng H, Chartrand SD, Zhang M, Saha S, Bardelli A, Jiang Y, St Martin TB, Nacht M, Teicher BA, Klinger KW, Sukumar S, Madden SL.

Cancer Res. 2004 Nov 1;64(21):7857-66. Erratum in: Cancer Res. 2004 Dec 1;64(23):8794.


Vascular gene expression in nonneoplastic and malignant brain.

Madden SL, Cook BP, Nacht M, Weber WD, Callahan MR, Jiang Y, Dufault MR, Zhang X, Zhang W, Walter-Yohrling J, Rouleau C, Akmaev VR, Wang CJ, Cao X, St Martin TB, Roberts BL, Teicher BA, Klinger KW, Stan RV, Lucey B, Carson-Walter EB, Laterra J, Walter KA.

Am J Pathol. 2004 Aug;165(2):601-8.


Gene expression profiling in a renal cell carcinoma cell line: dissecting VHL and hypoxia-dependent pathways.

Jiang Y, Zhang W, Kondo K, Klco JM, St Martin TB, Dufault MR, Madden SL, Kaelin WG Jr, Nacht M.

Mol Cancer Res. 2003 Apr;1(6):453-62.


Euthanasia: the three-in-one issue.

St Martin T.

Bayl Law Rev. 1975 Winter;27(1):62-7. No abstract available.


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