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Items: 33


Dengue virus-elicited tryptase induces endothelial permeability and shock.

Rathore AP, Mantri CK, Aman SA, Syenina A, Ooi J, Jagaraj CJ, Goh CC, Tissera H, Wilder-Smith A, Ng LG, Gubler DJ, St John AL.

J Clin Invest. 2019 Jul 2;130:4180-4193. doi: 10.1172/JCI128426.


Maternal immunity and antibodies to dengue virus promote infection and Zika virus-induced microcephaly in fetuses.

Rathore APS, Saron WAA, Lim T, Jahan N, St John AL.

Sci Adv. 2019 Feb 27;5(2):eaav3208. doi: 10.1126/sciadv.aav3208. eCollection 2019 Feb.


Japanese encephalitis virus neuropenetrance is driven by mast cell chymase.

Hsieh JT, Rathore APS, Soundarajan G, St John AL.

Nat Commun. 2019 Feb 11;10(1):706. doi: 10.1038/s41467-019-08641-z.


Adaptive immune responses to primary and secondary dengue virus infections.

St John AL, Rathore APS.

Nat Rev Immunol. 2019 Apr;19(4):218-230. doi: 10.1038/s41577-019-0123-x. Review.


Immune synapses between mast cells and γδ T cells limit viral infection.

Mantri CK, St John AL.

J Clin Invest. 2019 Mar 1;129(3):1094-1108. doi: 10.1172/JCI122530. Epub 2019 Feb 4.


Necroptosis of infiltrated macrophages drives Yersinia pestis dispersal within buboes.

Arifuzzaman M, Ang WXG, Choi HW, Nilles ML, St John AL, Abraham SN.

JCI Insight. 2018 Sep 20;3(18). pii: 122188. doi: 10.1172/jci.insight.122188. eCollection 2018 Sep 20.


Immune responses to dengue virus in the skin.

Rathore APS, St John AL.

Open Biol. 2018 Aug;8(8). pii: 180087. doi: 10.1098/rsob.180087. Review.


Flavivirus serocomplex cross-reactive immunity is protective by activating heterologous memory CD4 T cells.

Saron WAA, Rathore APS, Ting L, Ooi EE, Low J, Abraham SN, St John AL.

Sci Adv. 2018 Jul 4;4(7):eaar4297. doi: 10.1126/sciadv.aar4297. eCollection 2018 Jul.


Reprograming immunity to food allergens.

St John AL, Ang WXG, Rathore APS, Abraham SN.

J Allergy Clin Immunol. 2018 May;141(5):1936-1939.e2. doi: 10.1016/j.jaci.2018.01.020. Epub 2018 Feb 5. No abstract available.


Chymase Level Is a Predictive Biomarker of Dengue Hemorrhagic Fever in Pediatric and Adult Patients.

Tissera H, Rathore APS, Leong WY, Pike BL, Warkentien TE, Farouk FS, Syenina A, Eong Ooi E, Gubler DJ, Wilder-Smith A, St John AL.

J Infect Dis. 2017 Nov 27;216(9):1112-1121. doi: 10.1093/infdis/jix447.


Transcriptional Profiling Confirms the Therapeutic Effects of Mast Cell Stabilization in a Dengue Disease Model.

Morrison J, Rathore APS, Mantri CK, Aman SAB, Nishida A, St John AL.

J Virol. 2017 Aug 24;91(18). pii: e00617-17. doi: 10.1128/JVI.00617-17. Print 2017 Sep 15.


Cross-reactive antibodies enhance live attenuated virus infection for increased immunogenicity.

Chan KR, Wang X, Saron WAA, Gan ES, Tan HC, Mok DZL, Zhang SL, Lee YH, Liang C, Wijaya L, Ghosh S, Cheung YB, Tannenbaum SR, Abraham SN, St John AL, Low JGH, Ooi EE.

Nat Microbiol. 2016 Sep 19;1:16164. doi: 10.1038/nmicrobiol.2016.164.


Molecular determinants of plaque size as an indicator of dengue virus attenuation.

Goh KC, Tang CK, Norton DC, Gan ES, Tan HC, Sun B, Syenina A, Yousuf A, Ong XM, Kamaraj US, Cheung YB, Gubler DJ, Davidson A, St John AL, Sessions OM, Ooi EE.

Sci Rep. 2016 May 17;6:26100. doi: 10.1038/srep26100.


Maternal Antibody-Mediated Disease Enhancement in Type I Interferon-Deficient Mice Leads to Lethal Disease Associated with Liver Damage.

Martínez Gómez JM, Ong LC, Lam JH, Binte Aman SA, Libau EA, Lee PX, St John AL, Alonso S.

PLoS Negl Trop Dis. 2016 Mar 23;10(3):e0004536. doi: 10.1371/journal.pntd.0004536. eCollection 2016 Mar.


Neutrophils Self-Regulate Immune Complex-Mediated Cutaneous Inflammation through CXCL2.

Li JL, Lim CH, Tay FW, Goh CC, Devi S, Malleret B, Lee B, Bakocevic N, Chong SZ, Evrard M, Tanizaki H, Lim HY, Russell B, Renia L, Zolezzi F, Poidinger M, Angeli V, St John AL, Harris JE, Tey HL, Tan SM, Kabashima K, Weninger W, Larbi A, Ng LG.

J Invest Dermatol. 2016 Feb;136(2):416-424. doi: 10.1038/JID.2015.410.


Dengue vascular leakage is augmented by mast cell degranulation mediated by immunoglobulin Fcγ receptors.

Syenina A, Jagaraj CJ, Aman SA, Sridharan A, St John AL.

Elife. 2015 Mar 18;4. doi: 10.7554/eLife.05291.


S1P-Dependent trafficking of intracellular yersinia pestis through lymph nodes establishes Buboes and systemic infection.

St John AL, Ang WXG, Huang MN, Kunder CA, Chan EW, Gunn MD, Abraham SN.

Immunity. 2014 Sep 18;41(3):440-450. doi: 10.1016/j.immuni.2014.07.013.


Influence of mast cells on dengue protective immunity and immune pathology.

St John AL.

PLoS Pathog. 2013;9(12):e1003783. doi: 10.1371/journal.ppat.1003783. Epub 2013 Dec 19. No abstract available.


Barriers to preclinical investigations of anti-dengue immunity and dengue pathogenesis.

St John AL, Abraham SN, Gubler DJ.

Nat Rev Microbiol. 2013 Jun;11(6):420-6. doi: 10.1038/nrmicro3030. Epub 2013 May 8. Review.


Contributions of mast cells and vasoactive products, leukotrienes and chymase, to dengue virus-induced vascular leakage.

St John AL, Rathore AP, Raghavan B, Ng ML, Abraham SN.

Elife. 2013 Apr 30;2:e00481. doi: 10.7554/eLife.00481.


Innate immunity and its regulation by mast cells.

St John AL, Abraham SN.

J Immunol. 2013 May 1;190(9):4458-63. doi: 10.4049/jimmunol.1203420. Review.


Mast cell interleukin-10 drives localized tolerance in chronic bladder infection.

Chan CY, St John AL, Abraham SN.

Immunity. 2013 Feb 21;38(2):349-59. doi: 10.1016/j.immuni.2012.10.019. Epub 2013 Feb 15.


Synthetic mast-cell granules as adjuvants to promote and polarize immunity in lymph nodes.

St John AL, Chan CY, Staats HF, Leong KW, Abraham SN.

Nat Mater. 2012 Jan 22;11(3):250-7. doi: 10.1038/nmat3222.


Visual analytics of surveillance data on foodborne vibriosis, United States, 1973-2010.

Sims JN, Isokpehi RD, Cooper GA, Bass MP, Brown SD, St John AL, Gulig PA, Cohly HH.

Environ Health Insights. 2011;5:71-85. doi: 10.4137/EHI.S7806. Epub 2011 Nov 10.


Plasticity in mast cell responses during bacterial infections.

Chan CY, St John AL, Abraham SN.

Curr Opin Microbiol. 2012 Feb;15(1):78-84. doi: 10.1016/j.mib.2011.10.007. Epub 2011 Nov 4. Review.


Mast cell modulation of the vascular and lymphatic endothelium.

Kunder CA, St John AL, Abraham SN.

Blood. 2011 Nov 17;118(20):5383-93. doi: 10.1182/blood-2011-07-358432. Epub 2011 Sep 8. Review.


Immune surveillance by mast cells during dengue infection promotes natural killer (NK) and NKT-cell recruitment and viral clearance.

St John AL, Rathore AP, Yap H, Ng ML, Metcalfe DD, Vasudevan SG, Abraham SN.

Proc Natl Acad Sci U S A. 2011 May 31;108(22):9190-5. doi: 10.1073/pnas.1105079108. Epub 2011 May 16.


Mast cell-orchestrated immunity to pathogens.

Abraham SN, St John AL.

Nat Rev Immunol. 2010 Jun;10(6):440-52. doi: 10.1038/nri2782. Review.


Salmonella disrupts lymph node architecture by TLR4-mediated suppression of homeostatic chemokines.

St John AL, Abraham SN.

Nat Med. 2009 Nov;15(11):1259-65. doi: 10.1038/nm.2036. Epub 2009 Oct 25.


Mast cells augment adaptive immunity by orchestrating dendritic cell trafficking through infected tissues.

Shelburne CP, Nakano H, St John AL, Chan C, McLachlan JB, Gunn MD, Staats HF, Abraham SN.

Cell Host Microbe. 2009 Oct 22;6(4):331-42. doi: 10.1016/j.chom.2009.09.004.


Mast cell-derived particles deliver peripheral signals to remote lymph nodes.

Kunder CA, St John AL, Li G, Leong KW, Berwin B, Staats HF, Abraham SN.

J Exp Med. 2009 Oct 26;206(11):2455-67. doi: 10.1084/jem.20090805. Epub 2009 Oct 5.


Identification of a vimentin-like function associated molecule (FAM) on rat NK cells: evidence for receptor function.

Evans DL, Harris DT, Leary JH 3rd, St John AL, Jaso-Friedman L.

Scand J Immunol. 1993 Feb;37(2):131-42.


Detection of function-associated molecules on rat NK cells and their role in target cell lysis.

Jaso-Friedmann L, Leary JH 3rd, St John AL, Harris DT, Koren HS, Evans DL.

Cell Immunol. 1992 Apr 15;141(1):131-47.


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