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A salicylic acid derivative extends the lifespan of Caenorhabditis elegans by activating autophagy and the mitochondrial unfolded protein response.

Shamalnasab M, Gravel SP, St-Pierre J, Breton L, Jäger S, Aguilaniu H.

Aging Cell. 2018 Sep 7:e12830. doi: 10.1111/acel.12830. [Epub ahead of print]


Metabolic Profiles Associated With Metformin Efficacy in Cancer.

Andrzejewski S, Siegel PM, St-Pierre J.

Front Endocrinol (Lausanne). 2018 Aug 21;9:372. doi: 10.3389/fendo.2018.00372. eCollection 2018. Review.


Survey of diagnostic testing for respiratory syncytial virus (RSV) in adults: Infectious disease physician practices and implications for burden estimates.

Allen KE, Beekmann SE, Polgreen P, Poser S, St Pierre J, Santibañez S, Gerber SI, Kim L.

Diagn Microbiol Infect Dis. 2017 Dec 21. pii: S0732-8893(17)30407-8. doi: 10.1016/j.diagmicrobio.2017.12.011. [Epub ahead of print]


Interplay between ShcA Signaling and PGC-1α Triggers Targetable Metabolic Vulnerabilities in Breast Cancer.

Im YK, Najyb O, Gravel SP, McGuirk S, Ahn R, Avizonis DZ, Chénard V, Sabourin V, Hudson J, Pawson T, Topisirovic I, Pollak M, St-Pierre J, Ursini-Siegel J.

Cancer Res. 2018 Sep 1;78(17):4826-4838. doi: 10.1158/0008-5472.CAN-17-3696. Epub 2018 Jun 21.


Real-time Genomic Characterization of Advanced Pancreatic Cancer to Enable Precision Medicine.

Aguirre AJ, Nowak JA, Camarda ND, Moffitt RA, Ghazani AA, Hazar-Rethinam M, Raghavan S, Kim J, Brais LK, Ragon D, Welch MW, Reilly E, McCabe D, Marini L, Anderka K, Helvie K, Oliver N, Babic A, Da Silva A, Nadres B, Van Seventer EE, Shahzade HA, St Pierre JP, Burke KP, Clancy T, Cleary JM, Doyle LA, Jajoo K, McCleary NJ, Meyerhardt JA, Murphy JE, Ng K, Patel AK, Perez K, Rosenthal MH, Rubinson DA, Ryou M, Shapiro GI, Sicinska E, Silverman SG, Nagy RJ, Lanman RB, Knoerzer D, Welsch DJ, Yurgelun MB, Fuchs CS, Garraway LA, Getz G, Hornick JL, Johnson BE, Kulke MH, Mayer RJ, Miller JW, Shyn PB, Tuveson DA, Wagle N, Yeh JJ, Hahn WC, Corcoran RB, Carter SL, Wolpin BM.

Cancer Discov. 2018 Sep;8(9):1096-1111. doi: 10.1158/2159-8290.CD-18-0275. Epub 2018 Jun 14.


Natural disaster-related prenatal maternal stress is associated with alterations in placental glucocorticoid system: The QF2011 Queensland Flood Study.

St-Pierre J, Laplante DP, Elgbeili G, Dawson PA, Kildea S, King S, Vaillancourt C.

Psychoneuroendocrinology. 2018 Aug;94:38-48. doi: 10.1016/j.psyneuen.2018.04.027. Epub 2018 Apr 26.


Divergent Role of Estrogen-Related Receptor α in Lipid- and Fasting-Induced Hepatic Steatosis in Mice.

B'chir W, Dufour CR, Ouellet C, Yan M, Tam IS, Andrzejewski S, Xia H, Nabata K, St-Pierre J, Giguère V.

Endocrinology. 2018 May 1;159(5):2153-2164. doi: 10.1210/en.2018-00115.


The Essential Role of Primary Caregiver in Early Detection of Familial Hypercholesterolemia and Cardiovascular Prevention.

St-Pierre J, Ruel I, Genest J.

Curr Pediatr Rev. 2017;13(4):260-264. doi: 10.2174/1573396314666180221162556. Review.


Raman spectroscopic imaging for quantification of depth-dependent and local heterogeneities in native and engineered cartilage.

Albro MB, Bergholt MS, St-Pierre JP, Vinals Guitart A, Zlotnick HM, Evita EG, Stevens MM.

NPJ Regen Med. 2018 Feb 9;3:3. doi: 10.1038/s41536-018-0042-7. eCollection 2018.


RSK Regulates PFK-2 Activity to Promote Metabolic Rewiring in Melanoma.

Houles T, Gravel SP, Lavoie G, Shin S, Savall M, Méant A, Grondin B, Gaboury L, Yoon SO, St-Pierre J, Roux PP.

Cancer Res. 2018 May 1;78(9):2191-2204. doi: 10.1158/0008-5472.CAN-17-2215. Epub 2018 Feb 12.


Intersecting Evidence-Based Practice With a Lean Improvement Model.

Halm MA, Alway A, Bunn S, Dunn N, Hirschkorn M, Ramos B, St Pierre J.

J Nurs Care Qual. 2018 Oct/Dec;33(4):309-315. doi: 10.1097/NCQ.0000000000000313.


Raman spectroscopy imaging reveals interplay between atherosclerosis and medial calcification in the human aorta.

You AYF, Bergholt MS, St-Pierre JP, Kit-Anan W, Pence IJ, Chester AH, Yacoub MH, Bertazzo S, Stevens MM.

Sci Adv. 2017 Dec 6;3(12):e1701156. doi: 10.1126/sciadv.1701156. eCollection 2017 Dec.


A simple method to assess group difference in RT-qPCR reference gene selection using GeNorm: The case of the placental sex.

St-Pierre J, Grégoire JC, Vaillancourt C.

Sci Rep. 2017 Dec 5;7(1):16923. doi: 10.1038/s41598-017-16916-y.


Case Series: Report of the First Two Human Indigenous Cases of Cryptococcus gattii Infection in Eastern Canada.

St-Pierre J, Dufresne PJ, Carignan A, Lévesque É, Bernard F, Longtin J, LeBlanc L.

Mycopathologia. 2018 Apr;183(2):399-406. doi: 10.1007/s11046-017-0215-8. Epub 2017 Oct 30.


Recurrent Pneumothoraces in a Patient With Pulmonary Benign Metastasizing Leiomyoma.

Hann M, Manacheril R, St Pierre J, Gala R.

Ochsner J. 2017 Fall;17(3):284-287.


PGC-1α Promotes Breast Cancer Metastasis and Confers Bioenergetic Flexibility against Metabolic Drugs.

Andrzejewski S, Klimcakova E, Johnson RM, Tabariès S, Annis MG, McGuirk S, Northey JJ, Chénard V, Sriram U, Papadopoli DJ, Siegel PM, St-Pierre J.

Cell Metab. 2017 Nov 7;26(5):778-787.e5. doi: 10.1016/j.cmet.2017.09.006. Epub 2017 Oct 5.


AMPK Maintains Cellular Metabolic Homeostasis through Regulation of Mitochondrial Reactive Oxygen Species.

Rabinovitch RC, Samborska B, Faubert B, Ma EH, Gravel SP, Andrzejewski S, Raissi TC, Pause A, St-Pierre J, Jones RG.

Cell Rep. 2017 Oct 3;21(1):1-9. doi: 10.1016/j.celrep.2017.09.026.


mTOR Controls Mitochondrial Dynamics and Cell Survival via MTFP1.

Morita M, Prudent J, Basu K, Goyon V, Katsumura S, Hulea L, Pearl D, Siddiqui N, Strack S, McGuirk S, St-Pierre J, Larsson O, Topisirovic I, Vali H, McBride HM, Bergeron JJ, Sonenberg N.

Mol Cell. 2017 Sep 21;67(6):922-935.e5. doi: 10.1016/j.molcel.2017.08.013. Epub 2017 Sep 14.


The macrophage cytoskeleton acts as a contact sensor upon interaction with Entamoeba histolytica to trigger IL-1β secretion.

St-Pierre J, Moreau F, Cornick S, Quach J, Begum S, Aracely Fernandez L, Gorman H, Chadee K.

PLoS Pathog. 2017 Aug 24;13(8):e1006592. doi: 10.1371/journal.ppat.1006592. eCollection 2017 Aug.


Human placenta expresses both peripheral and neuronal isoform of tryptophan hydroxylase.

Laurent L, Deroy K, St-Pierre J, Côté F, Sanderson JT, Vaillancourt C.

Biochimie. 2017 Sep;140:159-165. doi: 10.1016/j.biochi.2017.07.008. Epub 2017 Jul 25.


PRL2 links magnesium flux and sex-dependent circadian metabolic rhythms.

Uetani N, Hardy S, Gravel SP, Kiessling S, Pietrobon A, Wong NN, Chénard V, Cermakian N, St-Pierre J, Tremblay ML.

JCI Insight. 2017 Jul 6;2(13). pii: 91722. doi: 10.1172/jci.insight.91722. [Epub ahead of print]


Progress Toward Containment of Poliovirus Type 2 - Worldwide, 2017.

Previsani N, Singh H, St Pierre J, Boualam L, Fournier-Caruana J, Sutter RW, Zaffran M; MEng.

MMWR Morb Mortal Wkly Rep. 2017 Jun 23;66(24):649-652. doi: 10.15585/mmwr.mm6624a5.


Preventing tissue fibrosis by local biomaterials interfacing of specific cryptic extracellular matrix information.

Horejs CM, St-Pierre JP, Ojala JRM, Steele JAM, da Silva PB, Rynne-Vidal A, Maynard SA, Hansel CS, Rodríguez-Fernández C, Mazo MM, You AYF, Wang AJ, von Erlach T, Tryggvason K, López-Cabrera M, Stevens MM.

Nat Commun. 2017 Jun 8;8:15509. doi: 10.1038/ncomms15509.


Assigning clinical meaning to somatic and germ-line whole-exome sequencing data in a prospective cancer precision medicine study.

Ghazani AA, Oliver NM, St Pierre JP, Garofalo A, Rainville IR, Hiller E, Treacy DJ, Rojas-Rudilla V, Wood S, Bair E, Parello M, Huang F, Giannakis M, Wilson FH, Stover EH, Corsello SM, Nguyen T, Rana HQ, Church AJ, Lowenstein C, Cibulskis C, Amin-Mansour A, Heng J, Brais L, Santos A, Bauer P, Waldron A, Lo P, Gorman M, Lydon CA, Welch M, McNamara P, Gabriel S, Sholl LM, Lindeman NI, Garber JE, Joffe S, Van Allen EM, Gray SW, Ja Nne PA, Garraway LA, Wagle N.

Genet Med. 2017 Jul;19(7):787-795. doi: 10.1038/gim.2016.191. Epub 2017 Jan 26.


Enhanced articular cartilage by human mesenchymal stem cells in enzymatically mediated transiently RGDS-functionalized collagen-mimetic hydrogels.

Parmar PA, St-Pierre JP, Chow LW, Spicer CD, Stoichevska V, Peng YY, Werkmeister JA, Ramshaw JAM, Stevens MM.

Acta Biomater. 2017 Mar 15;51:75-88. doi: 10.1016/j.actbio.2017.01.028. Epub 2017 Jan 10.


Raman Spectroscopy Reveals New Insights into the Zonal Organization of Native and Tissue-Engineered Articular Cartilage.

Bergholt MS, St-Pierre JP, Offeddu GS, Parmar PA, Albro MB, Puetzer JL, Oyen ML, Stevens MM.

ACS Cent Sci. 2016 Dec 28;2(12):885-895. doi: 10.1021/acscentsci.6b00222. Epub 2016 Nov 16.


Androgen-Dependent Repression of ERRγ Reprograms Metabolism in Prostate Cancer.

Audet-Walsh É, Yee T, McGuirk S, Vernier M, Ouellet C, St-Pierre J, Giguère V.

Cancer Res. 2017 Jan 15;77(2):378-389. doi: 10.1158/0008-5472.CAN-16-1204. Epub 2016 Nov 7.


Bromomethane Contamination in the Cathode of Proton Exchange Membrane Fuel Cells.

Zhai Y, Baturina O, Ramaker DE, Farquhar E, St-Pierre J, Swider-Lyons KE.

Electrochim Acta. 2016 Sep 20;213:482-489. Epub 2016 Jun 29.


Metabolomics Analyses of Cancer Cells in Controlled Microenvironments.

Gravel SP, Avizonis D, St-Pierre J.

Methods Mol Biol. 2016;1458:273-90. doi: 10.1007/978-1-4939-3801-8_20.


Unfractionated heparin after TBI reduces in vivo cerebrovascular inflammation, brain edema and accelerates cognitive recovery.

Nagata K, Kumasaka K, Browne KD, Li S, St-Pierre J, Cognetti J, Marks J, Johnson VE, Smith DH, Pascual JL.

J Trauma Acute Care Surg. 2016 Dec;81(6):1088-1094.


Inhibition of placental 11beta-hydroxysteroid dehydrogenase type 2 by lead.

St-Pierre J, Fraser M, Vaillancourt C.

Reprod Toxicol. 2016 Oct;65:133-138. doi: 10.1016/j.reprotox.2016.06.014. Epub 2016 Jul 22.


ERRα mediates metabolic adaptations driving lapatinib resistance in breast cancer.

Deblois G, Smith HW, Tam IS, Gravel SP, Caron M, Savage P, Labbé DP, Bégin LR, Tremblay ML, Park M, Bourque G, St-Pierre J, Muller WJ, Giguère V.

Nat Commun. 2016 Jul 12;7:12156. doi: 10.1038/ncomms12156.


Nucleus to Mitochondria: Lost in Transcription, Found in Translation.

St-Pierre J, Topisirovic I.

Dev Cell. 2016 Jun 20;37(6):490-2. doi: 10.1016/j.devcel.2016.06.003.


Harnessing the Versatility of Bacterial Collagen to Improve the Chondrogenic Potential of Porous Collagen Scaffolds.

Parmar PA, St-Pierre JP, Chow LW, Puetzer JL, Stoichevska V, Peng YY, Werkmeister JA, Ramshaw JA, Stevens MM.

Adv Healthc Mater. 2016 Jul;5(13):1656-66. doi: 10.1002/adhm.201600136. Epub 2016 May 24.


Temporally degradable collagen-mimetic hydrogels tuned to chondrogenesis of human mesenchymal stem cells.

Parmar PA, Skaalure SC, Chow LW, St-Pierre JP, Stoichevska V, Peng YY, Werkmeister JA, Ramshaw JA, Stevens MM.

Biomaterials. 2016 Aug;99:56-71. doi: 10.1016/j.biomaterials.2016.05.011. Epub 2016 May 10.


Chronic AMPK activation via loss of FLCN induces functional beige adipose tissue through PGC-1α/ERRα.

Yan M, Audet-Walsh É, Manteghi S, Dufour CR, Walker B, Baba M, St-Pierre J, Giguère V, Pause A.

Genes Dev. 2016 May 1;30(9):1034-46. doi: 10.1101/gad.281410.116.


nanoCAGE reveals 5' UTR features that define specific modes of translation of functionally related MTOR-sensitive mRNAs.

Gandin V, Masvidal L, Hulea L, Gravel SP, Cargnello M, McLaughlan S, Cai Y, Balanathan P, Morita M, Rajakumar A, Furic L, Pollak M, Porco JA Jr, St-Pierre J, Pelletier J, Larsson O, Topisirovic I.

Genome Res. 2016 May;26(5):636-48. doi: 10.1101/gr.197566.115. Epub 2016 Mar 16.


The PGC-1α/ERRα Axis Represses One-Carbon Metabolism and Promotes Sensitivity to Anti-folate Therapy in Breast Cancer.

Audet-Walsh É, Papadopoli DJ, Gravel SP, Yee T, Bridon G, Caron M, Bourque G, Giguère V, St-Pierre J.

Cell Rep. 2016 Feb 2;14(4):920-931. doi: 10.1016/j.celrep.2015.12.086. Epub 2016 Jan 21.


Effects of prenatal maternal stress on serotonin and fetal development.

St-Pierre J, Laurent L, King S, Vaillancourt C.

Placenta. 2016 Dec;48 Suppl 1:S66-S71. doi: 10.1016/j.placenta.2015.11.013. Epub 2015 Dec 2.


LRP1B, BRD2 and CACNA1D: new candidate genes in fetal metabolic programming of newborns exposed to maternal hyperglycemia.

Houde AA, Ruchat SM, Allard C, Baillargeon JP, St-Pierre J, Perron P, Gaudet D, Brisson D, Hivert MF, Bouchard L.

Epigenomics. 2015 Oct;7(7):1111-22. doi: 10.2217/epi.15.72. Epub 2015 Nov 20.


Chlorobenzene Poisoning and Recovery of Platinum-Based Cathodes in Proton Exchange Membrane Fuel Cells.

Zhai Y, Baturina O, Ramaker D, Farquhar E, St-Pierre J, Swider-Lyons K.

J Phys Chem C Nanomater Interfaces. 2015 Sep 3;119(35):20328-20338.


PDK1-Dependent Metabolic Reprogramming Dictates Metastatic Potential in Breast Cancer.

Dupuy F, Tabariès S, Andrzejewski S, Dong Z, Blagih J, Annis MG, Omeroglu A, Gao D, Leung S, Amir E, Clemons M, Aguilar-Mahecha A, Basik M, Vincent EE, St-Pierre J, Jones RG, Siegel PM.

Cell Metab. 2015 Oct 6;22(4):577-89. doi: 10.1016/j.cmet.2015.08.007. Epub 2015 Sep 10.


CDC's Early Response to a Novel Viral Disease, Middle East Respiratory Syndrome Coronavirus (MERS-CoV), September 2012-May 2014.

Williams HA, Dunville RL, Gerber SI, Erdman DD, Pesik N, Kuhar D, Mason KA, Haynes L, Rotz L, St Pierre J, Poser S, Bunga S, Pallansch MA, Swerdlow DL; MERS-CoV Working Group.

Public Health Rep. 2015 Jul-Aug;130(4):307-17.


Struggling for breath in Sherbrooke - 1st Symposium on "One mitochondrion, many diseases" in Sherbrooke, Québec, Canada, March 11th, 2015.

Braun RJ, Dumit VI, Monpays C, Roucou X, Serrano D, St-Pierre J, Waters PJ, Bates I, Gris D.

Microb Cell. 2015 May 20;2(6):208-213. doi: 10.15698/mic2015.06.207. No abstract available.


Collagen-mimetic peptide-modifiable hydrogels for articular cartilage regeneration.

Parmar PA, Chow LW, St-Pierre JP, Horejs CM, Peng YY, Werkmeister JA, Ramshaw JA, Stevens MM.

Biomaterials. 2015 Jun;54:213-25. doi: 10.1016/j.biomaterials.2015.02.079. Epub 2015 Apr 11.


A roadmap for interpreting (13)C metabolite labeling patterns from cells.

Buescher JM, Antoniewicz MR, Boros LG, Burgess SC, Brunengraber H, Clish CB, DeBerardinis RJ, Feron O, Frezza C, Ghesquiere B, Gottlieb E, Hiller K, Jones RG, Kamphorst JJ, Kibbey RG, Kimmelman AC, Locasale JW, Lunt SY, Maddocks OD, Malloy C, Metallo CM, Meuillet EJ, Munger J, Nöh K, Rabinowitz JD, Ralser M, Sauer U, Stephanopoulos G, St-Pierre J, Tennant DA, Wittmann C, Vander Heiden MG, Vazquez A, Vousden K, Young JD, Zamboni N, Fendt SM.

Curr Opin Biotechnol. 2015 Aug;34:189-201. doi: 10.1016/j.copbio.2015.02.003. Epub 2015 Feb 28. Review.


What nature used to allow to die, don't let modern habits damage after repair: preventable obesity risk in congenital heart disease.

St-Pierre J, Poirier P.

Can J Cardiol. 2015 Feb;31(2):109-11. doi: 10.1016/j.cjca.2014.09.020. Epub 2014 Sep 28. No abstract available.


mTOR coordinates protein synthesis, mitochondrial activity and proliferation.

Morita M, Gravel SP, Hulea L, Larsson O, Pollak M, St-Pierre J, Topisirovic I.

Cell Cycle. 2015;14(4):473-80. doi: 10.4161/15384101.2014.991572. Review.


Canadian Cardiovascular Society position statement on familial hypercholesterolemia.

Primary Panel:, Genest J, Hegele RA, Bergeron J, Brophy J, Carpentier A, Couture P, Davignon J, Dufour R, Frohlich J, Gaudet D, Gupta M, Krisnamoorthy P, Mancini J, McCrindle B, Raggi P, Ruel I, St-Pierre J.

Can J Cardiol. 2014 Dec;30(12):1471-81. doi: 10.1016/j.cjca.2014.09.028. Epub 2014 Oct 2. Review.


Serine deprivation enhances antineoplastic activity of biguanides.

Gravel SP, Hulea L, Toban N, Birman E, Blouin MJ, Zakikhani M, Zhao Y, Topisirovic I, St-Pierre J, Pollak M.

Cancer Res. 2014 Dec 15;74(24):7521-33. doi: 10.1158/0008-5472.CAN-14-2643-T. Epub 2014 Nov 6.

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