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Removal Notice. et al. Mult Scler. (2017)

Defining the clinical course of multiple sclerosis: the 2013 revisions. Lublin FD et al. Neurology. (2014)

Therapeutic Advances and Future Prospects in Progressive Forms of Multiple Sclerosis. Shirani A et al. Neurotherapeutics. (2016)

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Items: 1 to 50 of 258


Immunological Aspects of Approved MS Therapeutics.

Rommer PS, Milo R, Han MH, Satyanarayan S, Sellner J, Hauer L, Illes Z, Warnke C, Laurent S, Weber MS, Zhang Y, Stuve O.

Front Immunol. 2019 Jul 11;10:1564. doi: 10.3389/fimmu.2019.01564. eCollection 2019. Review.


Trials and therapies in secondary progressive MS, simplified.

Manouchehri N, Stüve O.

Nat Rev Neurol. 2019 Aug;15(8):431-432. doi: 10.1038/s41582-019-0233-x. No abstract available.


Effects of cladribine tablets on lymphocyte subsets in patients with multiple sclerosis: an extended analysis of surface markers.

Stuve O, Soelberg Soerensen P, Leist T, Giovannoni G, Hyvert Y, Damian D, Dangond F, Boschert U.

Ther Adv Neurol Disord. 2019 Jun 18;12:1756286419854986. doi: 10.1177/1756286419854986. eCollection 2019.


Clinical trials in multiple sclerosis: potential future trial designs.

Manouchehri N, Zhang Y, Salter A, Hussain RZ, Hartung HP, Hemmer B, Linker R, Segal BM, Cutter G, Stüve O.

Ther Adv Neurol Disord. 2019 May 13;12:1756286419847095. doi: 10.1177/1756286419847095. eCollection 2019. Review.


The role of B cells in multiple sclerosis: Current and future therapies.

Negron A, Robinson RR, Stüve O, Forsthuber TG.

Cell Immunol. 2019 May;339:10-23. doi: 10.1016/j.cellimm.2018.10.006. Epub 2018 Oct 21.


MAdCAM-1-Mediated Intestinal Lymphocyte Homing Is Critical for the Development of Active Experimental Autoimmune Encephalomyelitis.

Kuhbandner K, Hammer A, Haase S, Terbrack E, Hoffmann A, Schippers A, Wagner N, Hussain RZ, Miller-Little WA, Koh AY, Stoolman JS, Segal BM, Linker RA, Stüve O.

Front Immunol. 2019 Apr 26;10:903. doi: 10.3389/fimmu.2019.00903. eCollection 2019.


α4-integrin deficiency in B cells does not affect disease in a T-cell-mediated EAE disease model.

Hussain RZ, Cravens PD, Miller-Little WA, Doelger R, Granados V, Herndon E, Okuda DT, Eagar TN, Stüve O.

Neurol Neuroimmunol Neuroinflamm. 2019 Apr 16;6(4):e563. doi: 10.1212/NXI.0000000000000563. eCollection 2019 Jul. Erratum in: Neurol Neuroimmunol Neuroinflamm. 2019 Jul 05;6(4):e585.


Evolution of clinical trials in multiple sclerosis.

Zhang Y, Salter A, Wallström E, Cutter G, Stüve O.

Ther Adv Neurol Disord. 2019 Feb 21;12:1756286419826547. doi: 10.1177/1756286419826547. eCollection 2019. Review.


Neurofilament light chain: An important step toward a disease biomarker in multiple sclerosis.

Berger T, Stüve O.

Neurology. 2019 Mar 5;92(10):451-452. doi: 10.1212/WNL.0000000000007022. Epub 2019 Feb 8. No abstract available.


Simplification of combination antiretroviral therapy (cART) and the brain-a real-life experience.

Arendt G, Schlonies S, Orhan E, Stüve O.

J Neurovirol. 2019 Apr;25(2):174-182. doi: 10.1007/s13365-018-0701-x. Epub 2019 Jan 9.


TLR3 agonism re-establishes CNS immune competence during α4-integrin deficiency.

Hussain RZ, Cravens PC, Doelger R, Dentel B, Herndon E, Loof N, Tsai P, Okuda DT, Racke MK, Stüve O.

Ann Clin Transl Neurol. 2018 Oct 30;5(12):1543-1561. doi: 10.1002/acn3.664. eCollection 2018 Dec.


PDCB does not promote CNS autoimmunity in the context of genetic susceptibility but worsens its outcome.

Dubey D, Hussain RZ, Miller-Little WA, Salter A, Doelger R, Stüve O.

J Neuroimmunol. 2018 Oct 15;323:53-55. doi: 10.1016/j.jneuroim.2018.07.012. Epub 2018 Jul 25.


Presenilin1 regulates Th1 and Th17 effector responses but is not required for experimental autoimmune encephalomyelitis.

Cummings M, Arumanayagam ACS, Zhao P, Kannanganat S, Stuve O, Karandikar NJ, Eagar TN.

PLoS One. 2018 Aug 8;13(8):e0200752. doi: 10.1371/journal.pone.0200752. eCollection 2018.


Genome sequencing uncovers phenocopies in primary progressive multiple sclerosis.

Jia X, Madireddy L, Caillier S, Santaniello A, Esposito F, Comi G, Stuve O, Zhou Y, Taylor B, Kilpatrick T, Martinelli-Boneschi F, Cree BAC, Oksenberg JR, Hauser SL, Baranzini SE.

Ann Neurol. 2018 Jul;84(1):51-63. doi: 10.1002/ana.25263. Epub 2018 Jul 3.


Emerging drugs for primary progressive multiple sclerosis.

Narayan RN, Forsthuber T, Stüve O.

Expert Opin Emerg Drugs. 2018 Jun;23(2):97-110. doi: 10.1080/14728214.2018.1463370. Epub 2018 Apr 24. Review.


B cell-based therapies in CNS autoimmunity: differentiating CD19 and CD20 as therapeutic targets.

Forsthuber TG, Cimbora DM, Ratchford JN, Katz E, Stüve O.

Ther Adv Neurol Disord. 2018 Mar 21;11:1756286418761697. doi: 10.1177/1756286418761697. eCollection 2018. Review.


Similar Biophysical Abnormalities in Glomeruli and Podocytes from Two Distinct Models.

Embry AE, Liu Z, Henderson JM, Byfield FJ, Liu L, Yoon J, Wu Z, Cruz K, Moradi S, Gillombardo CB, Hussain RZ, Doelger R, Stuve O, Chang AN, Janmey PA, Bruggeman LA, Miller RT.

J Am Soc Nephrol. 2018 May;29(5):1501-1512. doi: 10.1681/ASN.2017050475. Epub 2018 Mar 23.


Natalizumab: Perspectives from the Bench to Bedside.

Shirani A, Stüve O.

Cold Spring Harb Perspect Med. 2018 Dec 3;8(12). pii: a029066. doi: 10.1101/cshperspect.a029066. Review.


Defining standard enzymatic dissociation methods for individual brains and spinal cords in EAE.

Hussain RZ, Miller-Little WA, Doelger R, Cutter GR, Loof N, Cravens PD, Stüve O.

Neurol Neuroimmunol Neuroinflamm. 2018 Jan 17;5(2):e437. doi: 10.1212/NXI.0000000000000437. eCollection 2018 Mar.


B-cell-targeted therapies in relapsing forms of MS.

Dubey D, Forsthuber T, Flanagan EP, Pittock SJ, Stüve O.

Neurol Neuroimmunol Neuroinflamm. 2017 Oct 23;4(6):e405. doi: 10.1212/NXI.0000000000000405. eCollection 2017 Nov. Review.


Effect of PF-00547659 on Central Nervous System Immune Surveillance and Circulating β7+ T Cells in Crohn's Disease: Report of the TOSCA Study.

D'Haens G, Vermeire S, Vogelsang H, Allez M, Desreumaux P, Van Gossum A, Sandborn WJ, Baumgart DC, Ransohoff RM, Comer GM, Ahmad A, Cataldi F, Cheng J, Clare R, Gorelick KJ, Kaminski A, Pradhan V, Rivers S, Sikpi MO, Zhang Y, Hassan-Zahraee M, Reinisch W, Stuve O.

J Crohns Colitis. 2018 Jan 24;12(2):188-196. doi: 10.1093/ecco-jcc/jjx128.


Normal intrathecal leukocyte cell number and composition do not decrease the incidence of post-lumbar puncture headache.

Stüve O, Cataldi F, Pradhan V, Gorelick KJ.

J Neuroimmunol. 2017 Sep 15;310:69-71. doi: 10.1016/j.jneuroim.2017.06.011. Epub 2017 Jun 30.


Laquinimod has no effects on brain volume or cellular CNS composition in the F1 3xTg-AD/C3H mouse model of Alzheimer's disease.

Hussain RZ, Miller-Little WA, Lambracht-Washington D, Jaramillo TC, Takahashi M, Zhang S, Fu M, Cutter GR, Hayardeny L, Powell CM, Rosenberg RN, Stüve O.

J Neuroimmunol. 2017 Aug 15;309:100-110. doi: 10.1016/j.jneuroim.2017.05.017. Epub 2017 May 26.


Natalizumab for Multiple Sclerosis: A Case in Point for the Impact of Translational Neuroimmunology.

Shirani A, Stüve O.

J Immunol. 2017 Feb 15;198(4):1381-1386. doi: 10.4049/jimmunol.1601358. Review.


High-dose immunosuppressive therapy and autologous HCT for relapsing-remitting MS.

Nash RA, Hutton GJ, Racke MK, Popat U, Devine SM, Steinmiller KC, Griffith LM, Muraro PA, Openshaw H, Sayre PH, Stuve O, Arnold DL, Wener MH, Georges GE, Wundes A, Kraft GH, Bowen JD.

Neurology. 2017 Feb 28;88(9):842-852. doi: 10.1212/WNL.0000000000003660. Epub 2017 Feb 1.


The major histocompatibility complex and antibody-mediated limbic encephalitis.

Stüve O, Vernino S.

Ann Neurol. 2017 Feb;81(2):181-182. doi: 10.1002/ana.24861. No abstract available.


Effect of Template Reporting of Brain MRIs for Multiple Sclerosis on Report Thoroughness and Neurologist-Rated Quality: Results of a Prospective Quality Improvement Project.

Dickerson E, Davenport MS, Syed F, Stuve O, Cohen JA, Rinker JR, Goldman MD, Segal BM, Foerster BR; Michigan Radiology Quality Collaborative.

J Am Coll Radiol. 2017 Mar;14(3):371-379.e1. doi: 10.1016/j.jacr.2016.09.037. Epub 2016 Dec 5.


Spotlight on daclizumab: its potential in the treatment of multiple sclerosis.

Milo R, Stüve O.

Degener Neurol Neuromuscul Dis. 2016 Nov 17;6:95-109. doi: 10.2147/DNND.S85747. eCollection 2016. Review.


IL-12/IL-23p40 Is Highly Expressed in Secondary Lymphoid Organs and the CNS during All Stages of EAE, but Its Deletion Does Not Affect Disease Perpetuation.

Cravens PD, Hussain RZ, Miller-Little WA, Ben LH, Segal BM, Herndon E, Stüve O.

PLoS One. 2016 Oct 25;11(10):e0165248. doi: 10.1371/journal.pone.0165248. eCollection 2016.


Targeting "bad" B cells in multiple sclerosis: Could laquinimod be part of the armamentarium?

Forsthuber TG, Stuve O.

Neurol Neuroimmunol Neuroinflamm. 2016 Sep 21;3(5):e283. eCollection 2016 Oct. No abstract available.


Ocrelizumab for the treatment of relapsing-remitting multiple sclerosis.

Menge T, Dubey D, Warnke C, Hartung HP, Stüve O.

Expert Rev Neurother. 2016 Oct;16(10):1131-9. doi: 10.1080/14737175.2016.1227242. Epub 2016 Sep 1. Review.


Safety and Efficacy of Siponimod (BAF312) in Patients With Relapsing-Remitting Multiple Sclerosis: Dose-Blinded, Randomized Extension of the Phase 2 BOLD Study.

Kappos L, Li DK, Stüve O, Hartung HP, Freedman MS, Hemmer B, Rieckmann P, Montalban X, Ziemssen T, Hunter B, Arnould S, Wallström E, Selmaj K.

JAMA Neurol. 2016 Sep 1;73(9):1089-98. doi: 10.1001/jamaneurol.2016.1451.


Diagnostic and therapeutic strategies for management of autoimmune encephalopathies.

Dubey D, Blackburn K, Greenberg B, Stuve O, Vernino S.

Expert Rev Neurother. 2016 Aug;16(8):937-49. doi: 10.1080/14737175.2016.1189328. Epub 2016 May 30. Review.


Managing Disability in Progressive Multiple Sclerosis.

Dubey D, Sguigna P, Stüve O.

Curr Treat Options Neurol. 2016 Jun;18(6):27. doi: 10.1007/s11940-016-0412-7. Review.


Tumefactive demyelination following herbal supplement use: Cause or coincidence?

Dubey D, Golden E, Suss A, Cano CA, Krishnan G, Stuve O.

J Postgrad Med. 2016 Apr-Jun;62(2):136-7. doi: 10.4103/0022-3859.180577. No abstract available.


In Memoriam: John F. Kurtzke, MD (1926-2015): A Founding Father of Neuroepidemiology and Pioneer of Modern Clinical Trial Design.

Frohman EM, Stüve O, Frohman TC, Lisak R.

JAMA Neurol. 2016 Apr;73(4):482-3. doi: 10.1001/jamaneurol.2016.0030. No abstract available.


Vestibular hypofunction after monosodium glutamate ingestion: broadening the spectrum of 'Chinese restaurant syndrome'.

Leussink VI, Hartung HP, Stüve O, Kieseier BC.

J Neurol. 2016 May;263(5):1027-1028. doi: 10.1007/s00415-016-8110-7. Epub 2016 Apr 8. No abstract available.


A Single Amino Acid Substitution Prevents Recognition of a Dominant Human Aquaporin-4 Determinant in the Context of HLA-DRB1*03:01 by a Murine TCR.

Arellano B, Hussain R, Miller-Little WA, Herndon E, Lambracht-Washington D, Eagar TN, Lewis R, Healey D, Vernino S, Greenberg BM, Stüve O.

PLoS One. 2016 Apr 7;11(4):e0152720. doi: 10.1371/journal.pone.0152720. eCollection 2016.


Update on monitoring and adverse effects of first generation disease modifying therapies and their recently approved versions in relapsing forms of multiple sclerosis.

Dubey D, Cano CA, Stüve O.

Curr Opin Neurol. 2016 Jun;29(3):272-7. doi: 10.1097/WCO.0000000000000320. Review.


Update on monitoring and adverse effects of approved second-generation disease-modifying therapies in relapsing forms of multiple sclerosis.

Dubey D, Cano CA, Stüve O.

Curr Opin Neurol. 2016 Jun;29(3):278-85. doi: 10.1097/WCO.0000000000000321. Review.


Will Biomarkers Determine What Is Next in Multiple Sclerosis?: Biomarkers in Multiple Sclerosis.

Stüve O, Racke MK.

JAMA Neurol. 2016 May 1;73(5):496-7. doi: 10.1001/jamaneurol.2015.4841. No abstract available.


Acute relapse after initiation of Siponimod in a patient with secondary progressive MS.

Hussain R, O'Leary S, Pacheco FM, Zacharias TE, Litvak P, Sguigna P, Marder E, Kia K, Kooner K, Stüve O.

J Neurol. 2016 Mar;263(3):606-10. doi: 10.1007/s00415-015-7999-6. Epub 2016 Feb 25.


Primary progressive multiple sclerosis--why we are failing.

Segal BM, Stüve O.

Lancet. 2016 Mar 12;387(10023):1032-1034. doi: 10.1016/S0140-6736(16)00158-6. Epub 2016 Jan 28. No abstract available.


B cell-directed therapies in multiple sclerosis.

Gasperi C, Stüve O, Hemmer B.

Neurodegener Dis Manag. 2016;6(1):37-47. doi: 10.2217/nmt.15.67. Review.


Therapeutic Advances and Future Prospects in Progressive Forms of Multiple Sclerosis.

Shirani A, Okuda DT, Stüve O.

Neurotherapeutics. 2016 Jan;13(1):58-69. doi: 10.1007/s13311-015-0409-z. Review.


The spectrum of autoimmune encephalopathies.

Dubey D, Sawhney A, Greenberg B, Lowden A, Warnack W, Khemani P, Stuve O, Vernino S.

J Neuroimmunol. 2015 Oct 15;287:93-7. doi: 10.1016/j.jneuroim.2015.08.014. Epub 2015 Aug 28.


Intractable and highly active relapsing multiple sclerosis - role of alemtuzumab.

Dubey D, Cano CA, Stuve O.

Neuropsychiatr Dis Treat. 2015 Sep 18;11:2405-14. doi: 10.2147/NDT.S90473. eCollection 2015. Review.


Smoking Beyond Multiple Sclerosis Diagnosis: A Risk Factor Still Worth Modifying.

Goldman MD, Stüve O.

JAMA Neurol. 2015 Oct;72(10):1105-6. doi: 10.1001/jamaneurol.2015.1805. No abstract available.


Update on biomarkers in neuromyelitis optica.

Melamed E, Levy M, Waters PJ, Sato DK, Bennett JL, John GR, Hooper DC, Saiz A, Bar-Or A, Kim HJ, Pandit L, Leite MI, Asgari N, Kissani N, Hintzen R, Marignier R, Jarius S, Marcelletti J, Smith TJ, Yeaman MR, Han MH, Aktas O, Apiwattanakul M, Banwell B, Bichuetti D, Broadley S, Cabre P, Chitnis T, De Seze J, Fujihara K, Greenberg B, Hellwig K, Iorio R, Jarius S, Klawiter E, Kleiter I, Lana-Peixoto M, Nakashima, O'Connor K, Palace J, Paul F, Prayoonwiwat N, Ruprecht K, Stuve O, Tedder T, Tenembaum S, Garrahan JP, Aires B, van Herle K, van Pelt D, Villoslada P, Waubant E, Weinshenker B, Wingerchuk D, Würfel J, Zamvil S.

Neurol Neuroimmunol Neuroinflamm. 2015 Jul 23;2(4):e134. doi: 10.1212/NXI.0000000000000134. eCollection 2015 Aug. Review.


In Memoriam: Jean Lindenmann (1924-2015): A Circuitous Interfering Power in Neurology.

Stüve O.

JAMA Neurol. 2015 Jun;72(6):728-9. doi: 10.1001/jamaneurol.2015.0439. No abstract available.


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