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Items: 1 to 50 of 158

1.

Genetic Engineering of Lactococcus lactis Co-producing Antigen and the Mucosal Adjuvant 3' 5'- cyclic di Adenosine Monophosphate (c-di-AMP) as a Design Strategy to Develop a Mucosal Vaccine Prototype.

Quintana I, Espariz M, Villar SR, González FB, Pacini MF, Cabrera G, Bontempi I, Prochetto E, Stülke J, Perez AR, Marcipar I, Blancato V, Magni C.

Front Microbiol. 2018 Sep 4;9:2100. doi: 10.3389/fmicb.2018.02100. eCollection 2018.

2.

Development of a replicating plasmid based on the native oriC in Mycoplasma pneumoniae.

Blötz C, Lartigue C, Valverde Timana Y, Ruiz E, Paetzold B, Busse J, Stülke J.

Microbiology. 2018 Sep 25. doi: 10.1099/mic.0.000711. [Epub ahead of print]

PMID:
30252643
3.

Making and breaking of an essential poison: the cyclases and phosphodiesterases that produce and degrade the essential second messenger cyclic di-AMP in bacteria.

Commichau FM, Heidemann JL, Ficner R, Stülke J.

J Bacteriol. 2018 Sep 17. pii: JB.00462-18. doi: 10.1128/JB.00462-18. [Epub ahead of print] Review.

PMID:
30224435
4.

Selective Pressure for Biofilm Formation in Bacillus subtilis: Differential Effect of Mutations in the Master Regulator SinR on Bistability.

Kampf J, Gerwig J, Kruse K, Cleverley R, Dormeyer M, Grünberger A, Kohlheyer D, Commichau FM, Lewis RJ, Stülke J.

MBio. 2018 Sep 4;9(5). pii: e01464-18. doi: 10.1128/mBio.01464-18.

5.

SubtiWiki in 2018: from genes and proteins to functional network annotation of the model organism Bacillus subtilis.

Zhu B, Stülke J.

Nucleic Acids Res. 2018 Jan 4;46(D1):D743-D748. doi: 10.1093/nar/gkx908.

6.

Coping with an Essential Poison: a Genetic Suppressor Analysis Corroborates a Key Function of c-di-AMP in Controlling Potassium Ion Homeostasis in Gram-Positive Bacteria.

Commichau FM, Stülke J.

J Bacteriol. 2018 May 24;200(12). pii: e00166-18. doi: 10.1128/JB.00166-18. Print 2018 Jun 15.

PMID:
29610213
7.

Structural basis for the regulatory interaction of the methylglyoxal synthase MgsA with the carbon flux regulator Crh in Bacillus subtilis.

Dickmanns A, Zschiedrich CP, Arens J, Parfentev I, Gundlach J, Hofele R, Neumann P, Urlaub H, Görke B, Ficner R, Stülke J.

J Biol Chem. 2018 Apr 20;293(16):5781-5792. doi: 10.1074/jbc.RA117.001289. Epub 2018 Mar 7.

PMID:
29514981
8.

Changes of DNA topology affect the global transcription landscape and allow rapid growth of a Bacillus subtilis mutant lacking carbon catabolite repression.

Reuß DR, Rath H, Thürmer A, Benda M, Daniel R, Völker U, Mäder U, Commichau FM, Stülke J.

Metab Eng. 2018 Jan;45:171-179. doi: 10.1016/j.ymben.2017.12.004. Epub 2017 Dec 11.

PMID:
29242163
9.

A Delicate Connection: c-di-AMP Affects Cell Integrity by Controlling Osmolyte Transport.

Commichau FM, Gibhardt J, Halbedel S, Gundlach J, Stülke J.

Trends Microbiol. 2018 Mar;26(3):175-185. doi: 10.1016/j.tim.2017.09.003. Epub 2017 Sep 28. Review.

PMID:
28965724
10.

Glycerol metabolism and its implication in virulence in Mycoplasma.

Blötz C, Stülke J.

FEMS Microbiol Rev. 2017 Sep 1;41(5):640-652. doi: 10.1093/femsre/fux033. Review.

PMID:
28961963
11.

Identification of c-di-AMP-Binding Proteins Using Magnetic Beads.

Kampf J, Gundlach J, Herzberg C, Treffon K, Stülke J.

Methods Mol Biol. 2017;1657:347-359. doi: 10.1007/978-1-4939-7240-1_27.

PMID:
28889307
12.

Erratum to: Of ions and messengers: an intricate link between potassium, glutamate, and cyclic di-AMP.

Gundlach J, Commichau FM, Stülke J.

Curr Genet. 2018 Feb;64(1):197. doi: 10.1007/s00294-017-0745-0.

PMID:
28884192
13.

Perspective of ions and messengers: an intricate link between potassium, glutamate, and cyclic di-AMP.

Gundlach J, Commichau FM, Stülke J.

Curr Genet. 2018 Feb;64(1):191-195. doi: 10.1007/s00294-017-0734-3. Epub 2017 Aug 20. Review. Erratum in: Curr Genet. 2017 Sep 7;:.

PMID:
28825218
14.

The contribution of bacterial genome engineering to sustainable development.

Reuß DR, Commichau FM, Stülke J.

Microb Biotechnol. 2017 Sep;10(5):1259-1263. doi: 10.1111/1751-7915.12784. Epub 2017 Aug 3.

15.

Identification of the Components Involved in Cyclic Di-AMP Signaling in Mycoplasma pneumoniae.

Blötz C, Treffon K, Kaever V, Schwede F, Hammer E, Stülke J.

Front Microbiol. 2017 Jul 13;8:1328. doi: 10.3389/fmicb.2017.01328. eCollection 2017.

16.

Adaptation of Bacillus subtilis to Life at Extreme Potassium Limitation.

Gundlach J, Herzberg C, Hertel D, Thürmer A, Daniel R, Link H, Stülke J.

MBio. 2017 Jul 5;8(4). pii: e00861-17. doi: 10.1128/mBio.00861-17.

17.

The Highly Conserved Asp23 Family Protein YqhY Plays a Role in Lipid Biosynthesis in Bacillus subtilis.

Tödter D, Gunka K, Stülke J.

Front Microbiol. 2017 May 19;8:883. doi: 10.3389/fmicb.2017.00883. eCollection 2017.

18.

Control of potassium homeostasis is an essential function of the second messenger cyclic di-AMP in Bacillus subtilis.

Gundlach J, Herzberg C, Kaever V, Gunka K, Hoffmann T, Weiß M, Gibhardt J, Thürmer A, Hertel D, Daniel R, Bremer E, Commichau FM, Stülke J.

Sci Signal. 2017 Apr 18;10(475). pii: eaal3011. doi: 10.1126/scisignal.aal3011.

PMID:
28420751
19.

Cyclic-di-GMP signalling meets extracellular polysaccharide synthesis in Bacillus subtilis.

Kampf J, Stülke J.

Environ Microbiol Rep. 2017 Jun;9(3):182-185. doi: 10.1111/1758-2229.12530. Epub 2017 Apr 3.

PMID:
28296273
20.

Hierarchical mutational events compensate for glutamate auxotrophy of a Bacillus subtilis gltC mutant.

Dormeyer M, Lübke AL, Müller P, Lentes S, Reuß DR, Thürmer A, Stülke J, Daniel R, Brantl S, Commichau FM.

Environ Microbiol Rep. 2017 Jun;9(3):279-289. doi: 10.1111/1758-2229.12531. Epub 2017 Apr 3.

PMID:
28294562
21.

Large-scale reduction of the Bacillus subtilis genome: consequences for the transcriptional network, resource allocation, and metabolism.

Reuß DR, Altenbuchner J, Mäder U, Rath H, Ischebeck T, Sappa PK, Thürmer A, Guérin C, Nicolas P, Steil L, Zhu B, Feussner I, Klumpp S, Daniel R, Commichau FM, Völker U, Stülke J.

Genome Res. 2017 Feb;27(2):289-299. doi: 10.1101/gr.215293.116. Epub 2016 Dec 13.

22.

Localization of Components of the RNA-Degrading Machine in Bacillus subtilis.

Cascante-Estepa N, Gunka K, Stülke J.

Front Microbiol. 2016 Sep 21;7:1492. eCollection 2016.

23.

The Blueprint of a Minimal Cell: MiniBacillus.

Reuß DR, Commichau FM, Gundlach J, Zhu B, Stülke J.

Microbiol Mol Biol Rev. 2016 Sep 28;80(4):955-987. Print 2016 Dec. Review.

24.

Complete Genome Sequence of Bacillus subtilis subsp. subtilis Strain ∆6.

Reuß DR, Thürmer A, Daniel R, Quax WJ, Stülke J.

Genome Announc. 2016 Jul 28;4(4). pii: e00759-16. doi: 10.1128/genomeA.00759-16.

25.

ThrR, a DNA-binding transcription factor involved in controlling threonine biosynthesis in Bacillus subtilis.

Rosenberg J, Müller P, Lentes S, Thiele MJ, Zeigler DR, Tödter D, Paulus H, Brantl S, Stülke J, Commichau FM.

Mol Microbiol. 2016 Sep;101(5):879-93. doi: 10.1111/mmi.13429. Epub 2016 Jun 27.

26.

Second Messenger Signaling in Bacillus subtilis: Accumulation of Cyclic di-AMP Inhibits Biofilm Formation.

Gundlach J, Rath H, Herzberg C, Mäder U, Stülke J.

Front Microbiol. 2016 May 25;7:804. doi: 10.3389/fmicb.2016.00804. eCollection 2016.

27.

Hydrogen sulfide is a novel potential virulence factor of Mycoplasma pneumoniae: characterization of the unusual cysteine desulfurase/desulfhydrase HapE.

Großhennig S, Ischebeck T, Gibhardt J, Busse J, Feussner I, Stülke J.

Mol Microbiol. 2016 Apr;100(1):42-54. doi: 10.1111/mmi.13300. Epub 2016 Feb 9.

28.

SubtiWiki 2.0--an integrated database for the model organism Bacillus subtilis.

Michna RH, Zhu B, Mäder U, Stülke J.

Nucleic Acids Res. 2016 Jan 4;44(D1):D654-62. doi: 10.1093/nar/gkv1006. Epub 2015 Oct 3.

29.

Trigger Enzymes: Coordination of Metabolism and Virulence Gene Expression.

Commichau FM, Stülke J.

Microbiol Spectr. 2015 Aug;3(4). doi: 10.1128/microbiolspec.MBP-0010-2014. Review.

PMID:
26350309
30.

The phosphoenolpyruvate:sugar phosphotransferase system is involved in sensitivity to the glucosylated bacteriocin sublancin.

Garcia De Gonzalo CV, Denham EL, Mars RA, Stülke J, van der Donk WA, van Dijl JM.

Antimicrob Agents Chemother. 2015 Nov;59(11):6844-54. doi: 10.1128/AAC.01519-15. Epub 2015 Aug 17.

31.

An Essential Poison: Synthesis and Degradation of Cyclic Di-AMP in Bacillus subtilis.

Gundlach J, Mehne FM, Herzberg C, Kampf J, Valerius O, Kaever V, Stülke J.

J Bacteriol. 2015 Oct;197(20):3265-74. doi: 10.1128/JB.00564-15. Epub 2015 Aug 3.

32.

Minor Cause--Major Effect: A Novel Mode of Control of Bistable Gene Expression.

Kampf J, Stülke J.

PLoS Genet. 2015 Jun 25;11(6):e1005229. doi: 10.1371/journal.pgen.1005229. eCollection 2015 Jun. No abstract available.

33.

Regulatory potential of post-translational modifications in bacteria.

Grangeasse C, Stülke J, Mijakovic I.

Front Microbiol. 2015 May 28;6:500. doi: 10.3389/fmicb.2015.00500. eCollection 2015. No abstract available.

34.

A jack of all trades: the multiple roles of the unique essential second messenger cyclic di-AMP.

Commichau FM, Dickmanns A, Gundlach J, Ficner R, Stülke J.

Mol Microbiol. 2015 Jul;97(2):189-204. doi: 10.1111/mmi.13026. Epub 2015 May 9. Review.

35.

Defining a minimal cell: essentiality of small ORFs and ncRNAs in a genome-reduced bacterium.

Lluch-Senar M, Delgado J, Chen WH, Lloréns-Rico V, O'Reilly FJ, Wodke JA, Unal EB, Yus E, Martínez S, Nichols RJ, Ferrar T, Vivancos A, Schmeisky A, Stülke J, van Noort V, Gavin AC, Bork P, Serrano L.

Mol Syst Biol. 2015 Jan 21;11(1):780. doi: 10.15252/msb.20145558.

36.

Structural and biochemical analysis of the essential diadenylate cyclase CdaA from Listeria monocytogenes.

Rosenberg J, Dickmanns A, Neumann P, Gunka K, Arens J, Kaever V, Stülke J, Ficner R, Commichau FM.

J Biol Chem. 2015 Mar 6;290(10):6596-606. doi: 10.1074/jbc.M114.630418. Epub 2015 Jan 20.

37.

Far from being well understood: multiple protein phosphorylation events control cell differentiation in Bacillus subtilis at different levels.

Gerwig J, Stülke J.

Front Microbiol. 2014 Dec 10;5:704. doi: 10.3389/fmicb.2014.00704. eCollection 2014. No abstract available.

38.

Identification, characterization, and structure analysis of the cyclic di-AMP-binding PII-like signal transduction protein DarA.

Gundlach J, Dickmanns A, Schröder-Tittmann K, Neumann P, Kaesler J, Kampf J, Herzberg C, Hammer E, Schwede F, Kaever V, Tittmann K, Stülke J, Ficner R.

J Biol Chem. 2015 Jan 30;290(5):3069-80. doi: 10.1074/jbc.M114.619619. Epub 2014 Nov 28.

39.

Caught in the act: RNA-Seq provides novel insights into mRNA degradation.

Gerwig J, Stülke J.

Mol Microbiol. 2014 Oct;94(1):5-8. doi: 10.1111/mmi.12769. Epub 2014 Sep 4.

40.

Mycoplasma pneumoniae thymidine phosphorylase.

Wang L, Schmidl SR, Stülke J.

Nucleosides Nucleotides Nucleic Acids. 2014;33(4-6):296-304. doi: 10.1080/15257770.2013.853783.

PMID:
24940683
41.

Control of the diadenylate cyclase CdaS in Bacillus subtilis: an autoinhibitory domain limits cyclic di-AMP production.

Mehne FM, Schröder-Tittmann K, Eijlander RT, Herzberg C, Hewitt L, Kaever V, Lewis RJ, Kuipers OP, Tittmann K, Stülke J.

J Biol Chem. 2014 Jul 25;289(30):21098-107. doi: 10.1074/jbc.M114.562066. Epub 2014 Jun 16.

42.

Impact of Hfq on the Bacillus subtilis transcriptome.

Hämmerle H, Amman F, Večerek B, Stülke J, Hofacker I, Bläsi U.

PLoS One. 2014 Jun 16;9(6):e98661. doi: 10.1371/journal.pone.0098661. eCollection 2014.

43.

Adaptation of Bacillus subtilis carbon core metabolism to simultaneous nutrient limitation and osmotic challenge: a multi-omics perspective.

Kohlstedt M, Sappa PK, Meyer H, Maaß S, Zaprasis A, Hoffmann T, Becker J, Steil L, Hecker M, van Dijl JM, Lalk M, Mäder U, Stülke J, Bremer E, Völker U, Wittmann C.

Environ Microbiol. 2014 Jun;16(6):1898-917. doi: 10.1111/1462-2920.12438. Epub 2014 Mar 31.

PMID:
24571712
44.

Phosphotransferase protein EIIANtr interacts with SpoT, a key enzyme of the stringent response, in Ralstonia eutropha H16.

Karstens K, Zschiedrich CP, Bowien B, Stülke J, Görke B.

Microbiology. 2014 Apr;160(Pt 4):711-22. doi: 10.1099/mic.0.075226-0. Epub 2014 Feb 10.

PMID:
24515609
45.

The protein tyrosine kinases EpsB and PtkA differentially affect biofilm formation in Bacillus subtilis.

Gerwig J, Kiley TB, Gunka K, Stanley-Wall N, Stülke J.

Microbiology. 2014 Apr;160(Pt 4):682-91. doi: 10.1099/mic.0.074971-0. Epub 2014 Feb 3.

46.

SubtiWiki-a database for the model organism Bacillus subtilis that links pathway, interaction and expression information.

Michna RH, Commichau FM, Tödter D, Zschiedrich CP, Stülke J.

Nucleic Acids Res. 2014 Jan;42(Database issue):D692-8. doi: 10.1093/nar/gkt1002. Epub 2013 Oct 30.

47.

The YmdB phosphodiesterase is a global regulator of late adaptive responses in Bacillus subtilis.

Diethmaier C, Newman JA, Kovács AT, Kaever V, Herzberg C, Rodrigues C, Boonstra M, Kuipers OP, Lewis RJ, Stülke J.

J Bacteriol. 2014 Jan;196(2):265-75. doi: 10.1128/JB.00826-13. Epub 2013 Oct 25.

48.

Mutational activation of the RocR activator and of a cryptic rocDEF promoter bypass loss of the initial steps of proline biosynthesis in Bacillus subtilis.

Zaprasis A, Hoffmann T, Wünsche G, Flórez LA, Stülke J, Bremer E.

Environ Microbiol. 2014 Mar;16(3):701-17. doi: 10.1111/1462-2920.12193. Epub 2013 Jul 19.

PMID:
23869754
49.

Dynamic localization of a transcription factor in Bacillus subtilis: the LicT antiterminator relocalizes in response to inducer availability.

Rothe FM, Wrede C, Lehnik-Habrink M, Görke B, Stülke J.

J Bacteriol. 2013 May;195(10):2146-54. doi: 10.1128/JB.00117-13. Epub 2013 Mar 8.

50.

Essential genes in Bacillus subtilis: a re-evaluation after ten years.

Commichau FM, Pietack N, Stülke J.

Mol Biosyst. 2013 Jun;9(6):1068-75. doi: 10.1039/c3mb25595f. Epub 2013 Feb 18. Review.

PMID:
23420519

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