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Items: 36

1.

ABHD15 regulates adipose tissue lipolysis and hepatic lipid accumulation.

Stöckli J, Zadoorian A, Cooke KC, Deshpande V, Yau B, Herrmann G, Kebede MA, Humphrey SJ, James DE.

Mol Metab. 2019 Jul;25:83-94. doi: 10.1016/j.molmet.2019.05.002. Epub 2019 May 6.

2.

Tankyrase modulates insulin sensitivity in skeletal muscle cells by regulating the stability of GLUT4 vesicle proteins.

Su Z, Deshpande V, James DE, Stöckli J.

J Biol Chem. 2018 Jun 1;293(22):8578-8587. doi: 10.1074/jbc.RA117.001058. Epub 2018 Apr 18.

3.

Mitochondrial oxidative stress causes insulin resistance without disrupting oxidative phosphorylation.

Fazakerley DJ, Minard AY, Krycer JR, Thomas KC, Stöckli J, Harney DJ, Burchfield JG, Maghzal GJ, Caldwell ST, Hartley RC, Stocker R, Murphy MP, James DE.

J Biol Chem. 2018 May 11;293(19):7315-7328. doi: 10.1074/jbc.RA117.001254. Epub 2018 Mar 29.

4.

High dietary fat and sucrose results in an extensive and time-dependent deterioration in health of multiple physiological systems in mice.

Burchfield JG, Kebede MA, Meoli CC, Stöckli J, Whitworth PT, Wright AL, Hoffman NJ, Minard AY, Ma X, Krycer JR, Nelson ME, Tan SX, Yau B, Thomas KC, Wee NKY, Khor EC, Enriquez RF, Vissel B, Biden TJ, Baldock PA, Hoehn KL, Cantley J, Cooney GJ, James DE, Fazakerley DJ.

J Biol Chem. 2018 Apr 13;293(15):5731-5745. doi: 10.1074/jbc.RA117.000808. Epub 2018 Feb 13.

5.

Metabolomic analysis of insulin resistance across different mouse strains and diets.

Stöckli J, Fisher-Wellman KH, Chaudhuri R, Zeng XY, Fazakerley DJ, Meoli CC, Thomas KC, Hoffman NJ, Mangiafico SP, Xirouchaki CE, Yang CH, Ilkayeva O, Wong K, Cooney GJ, Andrikopoulos S, Muoio DM, James DE.

J Biol Chem. 2017 Nov 24;292(47):19135-19145. doi: 10.1074/jbc.M117.818351. Epub 2017 Oct 5.

6.

A novel Rab10-EHBP1-EHD2 complex essential for the autophagic engulfment of lipid droplets.

Li Z, Schulze RJ, Weller SG, Krueger EW, Schott MB, Zhang X, Casey CA, Liu J, Stöckli J, James DE, McNiven MA.

Sci Adv. 2016 Dec 16;2(12):e1601470. doi: 10.1126/sciadv.1601470. eCollection 2016 Dec.

7.

Hyperactivation of the Insulin Signaling Pathway Improves Intracellular Proteostasis by Coordinately Up-regulating the Proteostatic Machinery in Adipocytes.

Minard AY, Wong MK, Chaudhuri R, Tan SX, Humphrey SJ, Parker BL, Yang JY, Laybutt DR, Cooney GJ, Coster AC, Stöckli J, James DE.

J Biol Chem. 2016 Dec 2;291(49):25629-25640. Epub 2016 Oct 13.

8.

mTORC1 Is a Major Regulatory Node in the FGF21 Signaling Network in Adipocytes.

Minard AY, Tan SX, Yang P, Fazakerley DJ, Domanova W, Parker BL, Humphrey SJ, Jothi R, Stöckli J, James DE.

Cell Rep. 2016 Sep 27;17(1):29-36. doi: 10.1016/j.celrep.2016.08.086.

9.

Cross-species gene expression analysis identifies a novel set of genes implicated in human insulin sensitivity.

Chaudhuri R, Khoo PS, Tonks K, Junutula JR, Kolumam G, Modrusan Z, Samocha-Bonet D, Meoli CC, Hocking S, Fazakerley DJ, Stöckli J, Hoehn KL, Greenfield JR, Yang JYH, James DE.

NPJ Syst Biol Appl. 2015 Nov 12;1:15010. doi: 10.1038/npjsba.2015.10. eCollection 2015.

10.

Global Phosphoproteomic Analysis of Human Skeletal Muscle Reveals a Network of Exercise-Regulated Kinases and AMPK Substrates.

Hoffman NJ, Parker BL, Chaudhuri R, Fisher-Wellman KH, Kleinert M, Humphrey SJ, Yang P, Holliday M, Trefely S, Fazakerley DJ, Stöckli J, Burchfield JG, Jensen TE, Jothi R, Kiens B, Wojtaszewski JF, Richter EA, James DE.

Cell Metab. 2015 Nov 3;22(5):922-35. doi: 10.1016/j.cmet.2015.09.001. Epub 2015 Oct 1. Erratum in: Cell Metab. 2015 Nov 3;22(5):948.

11.

Kinome Screen Identifies PFKFB3 and Glucose Metabolism as Important Regulators of the Insulin/Insulin-like Growth Factor (IGF)-1 Signaling Pathway.

Trefely S, Khoo PS, Krycer JR, Chaudhuri R, Fazakerley DJ, Parker BL, Sultani G, Lee J, Stephan JP, Torres E, Jung K, Kuijl C, James DE, Junutula JR, Stöckli J.

J Biol Chem. 2015 Oct 23;290(43):25834-46. doi: 10.1074/jbc.M115.658815. Epub 2015 Sep 4.

12.

PhosphOrtholog: a web-based tool for cross-species mapping of orthologous protein post-translational modifications.

Chaudhuri R, Sadrieh A, Hoffman NJ, Parker BL, Humphrey SJ, Stöckli J, Hill AP, James DE, Yang JY.

BMC Genomics. 2015 Aug 19;16:617. doi: 10.1186/s12864-015-1820-x.

13.

Proteomic Analysis of GLUT4 Storage Vesicles Reveals Tumor Suppressor Candidate 5 (TUSC5) as a Novel Regulator of Insulin Action in Adipocytes.

Fazakerley DJ, Naghiloo S, Chaudhuri R, Koumanov F, Burchfield JG, Thomas KC, Krycer JR, Prior MJ, Parker BL, Murrow BA, Stöckli J, Meoli CC, Holman GD, James DE.

J Biol Chem. 2015 Sep 25;290(39):23528-42. doi: 10.1074/jbc.M115.657361. Epub 2015 Aug 3.

14.

Selective insulin resistance in adipocytes.

Tan SX, Fisher-Wellman KH, Fazakerley DJ, Ng Y, Pant H, Li J, Meoli CC, Coster AC, Stöckli J, James DE.

J Biol Chem. 2015 May 1;290(18):11337-48. doi: 10.1074/jbc.M114.623686. Epub 2015 Feb 26.

15.

The RabGAP TBC1D1 plays a central role in exercise-regulated glucose metabolism in skeletal muscle.

Stöckli J, Meoli CC, Hoffman NJ, Fazakerley DJ, Pant H, Cleasby ME, Ma X, Kleinert M, Brandon AE, Lopez JA, Cooney GJ, James DE.

Diabetes. 2015 Jun;64(6):1914-22. doi: 10.2337/db13-1489. Epub 2015 Jan 9.

16.

DOC2 isoforms play dual roles in insulin secretion and insulin-stimulated glucose uptake.

Li J, Cantley J, Burchfield JG, Meoli CC, Stöckli J, Whitworth PT, Pant H, Chaudhuri R, Groffen AJ, Verhage M, James DE.

Diabetologia. 2014 Oct;57(10):2173-82. doi: 10.1007/s00125-014-3312-y. Epub 2014 Jul 9.

PMID:
25005332
17.

Systemic VEGF-A neutralization ameliorates diet-induced metabolic dysfunction.

Wu LE, Meoli CC, Mangiafico SP, Fazakerley DJ, Cogger VC, Mohamad M, Pant H, Kang MJ, Powter E, Burchfield JG, Xirouchaki CE, Mikolaizak AS, Stöckli J, Kolumam G, van Bruggen N, Gamble JR, Le Couteur DG, Cooney GJ, Andrikopoulos S, James DE.

Diabetes. 2014 Aug;63(8):2656-67. doi: 10.2337/db13-1665. Epub 2014 Apr 2.

18.

Dynamic adipocyte phosphoproteome reveals that Akt directly regulates mTORC2.

Humphrey SJ, Yang G, Yang P, Fazakerley DJ, Stöckli J, Yang JY, James DE.

Cell Metab. 2013 Jun 4;17(6):1009-20. doi: 10.1016/j.cmet.2013.04.010. Epub 2013 May 16.

19.

Protein kinase Cε modulates insulin receptor localization and trafficking in mouse embryonic fibroblasts.

Pedersen DJ, Diakanastasis B, Stöckli J, Schmitz-Peiffer C.

PLoS One. 2013;8(3):e58046. doi: 10.1371/journal.pone.0058046. Epub 2013 Mar 1.

20.

Impaired Akt phosphorylation in insulin-resistant human muscle is accompanied by selective and heterogeneous downstream defects.

Tonks KT, Ng Y, Miller S, Coster AC, Samocha-Bonet D, Iseli TJ, Xu A, Patrick E, Yang JY, Junutula JR, Modrusan Z, Kolumam G, Stöckli J, Chisholm DJ, James DE, Greenfield JR.

Diabetologia. 2013 Apr;56(4):875-85. doi: 10.1007/s00125-012-2811-y. Epub 2013 Jan 24.

PMID:
23344726
21.

Membrane curvature protein exhibits interdomain flexibility and binds a small GTPase.

King GJ, Stöckli J, Hu SH, Winnen B, Duprez WG, Meoli CC, Junutula JR, Jarrott RJ, James DE, Whitten AE, Martin JL.

J Biol Chem. 2012 Nov 30;287(49):40996-1006. doi: 10.1074/jbc.M112.349803. Epub 2012 Oct 10.

22.

The Rab GTPase-activating protein TBC1D4/AS160 contains an atypical phosphotyrosine-binding domain that interacts with plasma membrane phospholipids to facilitate GLUT4 trafficking in adipocytes.

Tan SX, Ng Y, Burchfield JG, Ramm G, Lambright DG, Stöckli J, James DE.

Mol Cell Biol. 2012 Dec;32(24):4946-59. doi: 10.1128/MCB.00761-12. Epub 2012 Oct 8.

23.

TBC1D13 is a RAB35 specific GAP that plays an important role in GLUT4 trafficking in adipocytes.

Davey JR, Humphrey SJ, Junutula JR, Mishra AK, Lambright DG, James DE, Stöckli J.

Traffic. 2012 Oct;13(10):1429-41. doi: 10.1111/j.1600-0854.2012.01397.x. Epub 2012 Jul 29.

24.

GLUT4 exocytosis.

Stöckli J, Fazakerley DJ, James DE.

J Cell Sci. 2011 Dec 15;124(Pt 24):4147-59. doi: 10.1242/jcs.097063. Review.

25.

Amplification and demultiplexing in insulin-regulated Akt protein kinase pathway in adipocytes.

Tan SX, Ng Y, Meoli CC, Kumar A, Khoo PS, Fazakerley DJ, Junutula JR, Vali S, James DE, Stöckli J.

J Biol Chem. 2012 Feb 24;287(9):6128-38. doi: 10.1074/jbc.M111.318238. Epub 2011 Dec 29.

26.

Insulin-regulated trafficking of GLUT4 requires ubiquitination.

Lamb CA, McCann RK, Stöckli J, James DE, Bryant NJ.

Traffic. 2010 Nov;11(11):1445-54. doi: 10.1111/j.1600-0854.2010.01113.x. Epub 2010 Sep 20.

27.

Muscling in on GLUT4 kinetics.

Stöckli J, Fazakerley DJ, Coster AC, Holman GD, James DE.

Commun Integr Biol. 2010 May;3(3):260-2.

28.

Kinetic evidence for unique regulation of GLUT4 trafficking by insulin and AMP-activated protein kinase activators in L6 myotubes.

Fazakerley DJ, Holman GD, Marley A, James DE, Stöckli J, Coster AC.

J Biol Chem. 2010 Jan 15;285(3):1653-60. doi: 10.1074/jbc.M109.051185. Epub 2009 Nov 13.

29.

Cluster analysis of insulin action in adipocytes reveals a key role for Akt at the plasma membrane.

Ng Y, Ramm G, Burchfield JG, Coster AC, Stöckli J, James DE.

J Biol Chem. 2010 Jan 22;285(4):2245-57. doi: 10.1074/jbc.M109.060236. Epub 2009 Nov 6.

30.

Oligomeric resistin impairs insulin and AICAR-stimulated glucose uptake in mouse skeletal muscle by inhibiting GLUT4 translocation.

Jørgensen SB, Honeyman J, Oakhill JS, Fazakerley D, Stöckli J, Kemp BE, Steinberg GR.

Am J Physiol Endocrinol Metab. 2009 Jul;297(1):E57-66. doi: 10.1152/ajpendo.90744.2008. Epub 2009 May 12.

31.

Insulin action under arrestin.

Stöckli J, James DE.

Cell Metab. 2009 Mar;9(3):213-4. doi: 10.1016/j.cmet.2009.02.005.

32.

Regulation of glucose transporter 4 translocation by the Rab guanosine triphosphatase-activating protein AS160/TBC1D4: role of phosphorylation and membrane association.

Stöckli J, Davey JR, Hohnen-Behrens C, Xu A, James DE, Ramm G.

Mol Endocrinol. 2008 Dec;22(12):2703-15. doi: 10.1210/me.2008-0111. Epub 2008 Sep 18.

33.

Characterization of the role of the Rab GTPase-activating protein AS160 in insulin-regulated GLUT4 trafficking.

Larance M, Ramm G, Stöckli J, van Dam EM, Winata S, Wasinger V, Simpson F, Graham M, Junutula JR, Guilhaus M, James DE.

J Biol Chem. 2005 Nov 11;280(45):37803-13. Epub 2005 Sep 8.

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