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Items: 1 to 50 of 110

1.

IL-17 Production by γδ+ T Cells Is Critical for Inducing Th17 Responses in the Female Genital Tract and Regulated by Estradiol and Microbiota.

Anipindi VC, Bagri P, Dizzell SE, Jiménez-Saiz R, Jordana M, Snider DP, Stämpfli MR, Kaushic C.

Immunohorizons. 2019 Jul 17;3(7):317-330. doi: 10.4049/immunohorizons.1900040.

PMID:
31356161
2.

c-Myb Exacerbates Atherosclerosis through Regulation of Protective IgM-Producing Antibody-Secreting Cells.

Shikatani EA, Besla R, Ensan S, Upadhye A, Khyzha N, Li A, Emoto T, Chiu F, Degousee N, Moreau JM, Perry HM, Thayaparan D, Cheng HS, Pacheco S, Smyth D, Noyan H, Zavitz CCJ, Bauer CMT, Hilgendorf I, Libby P, Swirski FK, Gommerman JL, Fish JE, Stampfli MR, Cybulsky MI, Rubin BB, Paige CJ, Bender TP, McNamara CA, Husain M, Robbins CS.

Cell Rep. 2019 May 21;27(8):2304-2312.e6. doi: 10.1016/j.celrep.2019.04.090.

3.

Statins Promote Interleukin-1β-Dependent Adipocyte Insulin Resistance Through Lower Prenylation, Not Cholesterol.

Henriksbo BD, Tamrakar AK, Xu J, Duggan BM, Cavallari JF, Phulka J, Stampfli MR, Ashkar AA, Schertzer JD.

Diabetes. 2019 Jul;68(7):1441-1448. doi: 10.2337/db18-0999. Epub 2019 Apr 22.

PMID:
31010959
4.

The impact of cigarette smoke exposure, COPD, or asthma status on ABC transporter gene expression in human airway epithelial cells.

Aguiar JA, Tamminga A, Lobb B, Huff RD, Nguyen JP, Kim Y, Dvorkin-Gheva A, Stampfli MR, Doxey AC, Hirota JA.

Sci Rep. 2019 Jan 17;9(1):153. doi: 10.1038/s41598-018-36248-9.

5.

The Overlap of Lung Tissue Transcriptome of Smoke Exposed Mice with Human Smoking and COPD.

Obeidat M, Dvorkin-Gheva A, Li X, Bossé Y, Brandsma CA, Nickle DC, Hansbro PM, Faner R, Agusti A, Paré PD, Stampfli MR, Sin DD.

Sci Rep. 2018 Aug 8;8(1):11881. doi: 10.1038/s41598-018-30313-z.

6.

The immune system as a victim and aggressor in chronic obstructive pulmonary disease.

McGrath JJC, Stampfli MR.

J Thorac Dis. 2018 Jun;10(Suppl 17):S2011-S2017. doi: 10.21037/jtd.2018.05.63. No abstract available.

7.

Does Compromised Immune Exclusion Drive Inflammatory Processes in Chronic Obstructive Pulmonary Disease?

Stampfli MR, Churg AM.

Am J Respir Cell Mol Biol. 2018 Jun;58(6):671-672. doi: 10.1165/rcmb.2018-0039ED. No abstract available.

PMID:
29856258
8.

Female Sex and Gender in Lung/Sleep Health and Disease. Increased Understanding of Basic Biological, Pathophysiological, and Behavioral Mechanisms Leading to Better Health for Female Patients with Lung Disease.

Han MK, Arteaga-Solis E, Blenis J, Bourjeily G, Clegg DJ, DeMeo D, Duffy J, Gaston B, Heller NM, Hemnes A, Henske EP, Jain R, Lahm T, Lancaster LH, Lee J, Legato MJ, McKee S, Mehra R, Morris A, Prakash YS, Stampfli MR, Gopal-Srivastava R, Laposky AD, Punturieri A, Reineck L, Tigno X, Clayton J.

Am J Respir Crit Care Med. 2018 Oct 1;198(7):850-858. doi: 10.1164/rccm.201801-0168WS. Review.

PMID:
29746147
9.

Identification of microRNAs as potential markers of ovarian toxicity.

Furlong HC, Stämpfli MR, Gannon AM, Foster WG.

J Appl Toxicol. 2018 May;38(5):744-752. doi: 10.1002/jat.3583. Epub 2018 Jan 29.

10.

Identification of Drug Candidates to Suppress Cigarette Smoke-induced Inflammation via Connectivity Map Analyses.

Vanderstocken G, Dvorkin-Gheva A, Shen P, Brandsma CA, Obeidat M, Bossé Y, Hassell JA, Stampfli MR.

Am J Respir Cell Mol Biol. 2018 Jun;58(6):727-735. doi: 10.1165/rcmb.2017-0202OC.

PMID:
29256623
11.

Novel Role for Interleukin-17 in Enhancing Type 1 Helper T Cell Immunity in the Female Genital Tract following Mucosal Herpes Simplex Virus 2 Vaccination.

Bagri P, Anipindi VC, Nguyen PV, Vitali D, Stämpfli MR, Kaushic C.

J Virol. 2017 Nov 14;91(23). pii: e01234-17. doi: 10.1128/JVI.01234-17. Print 2017 Dec 1.

12.

Streptococcus pneumoniae Colonization Is Required To Alter the Nasal Microbiota in Cigarette Smoke-Exposed Mice.

Shen P, Whelan FJ, Schenck LP, McGrath JJC, Vanderstocken G, Bowdish DME, Surette MG, Stämpfli MR.

Infect Immun. 2017 Sep 20;85(10). pii: e00434-17. doi: 10.1128/IAI.00434-17. Print 2017 Oct.

13.

Targeting Interleukin-17 signalling in cigarette smoke-induced lung disease: Mechanistic concepts and therapeutic opportunities.

Roos AB, Stampfli MR.

Pharmacol Ther. 2017 Oct;178:123-131. doi: 10.1016/j.pharmthera.2017.04.001. Epub 2017 Apr 21. Review.

PMID:
28438639
14.

Increased IL-17RA and IL-17RC in End-Stage COPD and the Contribution to Mast Cell Secretion of FGF-2 and VEGF.

Roos AB, Mori M, Gura HK, Lorentz A, Bjermer L, Hoffmann HJ, Erjefält JS, Stampfli MR.

Respir Res. 2017 Mar 15;18(1):48. doi: 10.1186/s12931-017-0534-9.

15.

Role of BAFF in pulmonary autoantibody responses induced by chronic cigarette smoke exposure in mice.

Morissette MC, Gao Y, Shen P, Thayaparan D, Bérubé JC, Paré PD, Brandsma CA, Hao K, Bossé Y, Ettinger R, Herbst R, Humbles AA, Kolbeck R, Zhong N, Chen R, Stämpfli MR.

Physiol Rep. 2016 Dec;4(24). pii: e13057. doi: 10.14814/phy2.13057.

16.

Total particulate matter concentration skews cigarette smoke's gene expression profile.

Dvorkin-Gheva A, Vanderstocken G, Yildirim AÖ, Brandsma CA, Obeidat M, Bossé Y, Hassell JA, Stampfli MR.

ERJ Open Res. 2016 Nov 9;2(4). pii: 00029-2016. eCollection 2016 Oct.

17.

Induction of pulmonary antibodies against oxidized lipids in mice exposed to cigarette smoke.

Thayaparan D, Shen P, Stämpfli MR, Morissette MC.

Respir Res. 2016 Aug 4;17(1):97. doi: 10.1186/s12931-016-0416-6.

18.

Correction: Estradiol Enhances CD4+ T-Cell Anti-Viral Immunity by Priming Vaginal DCs to Induce Th17 Responses via an IL-1-Dependent Pathway.

Anipindi VC, Bagri P, Roth K, Dizzell SE, Nguyen PV, Shaler CR, Chu DK, Jiménez-Saiz R, Liang H, Swift SL, Nazli A, Kafka JK, Bramson J, Xing Z, Jordana M, Wan Y, Snider DP, Stampfli MR, Kaushic C.

PLoS Pathog. 2016 Jun 8;12(6):e1005706. doi: 10.1371/journal.ppat.1005706. eCollection 2016 Jun.

19.

Estradiol Enhances CD4+ T-Cell Anti-Viral Immunity by Priming Vaginal DCs to Induce Th17 Responses via an IL-1-Dependent Pathway.

Anipindi VC, Bagri P, Roth K, Dizzell SE, Nguyen PV, Shaler CR, Chu DK, Jiménez-Saiz R, Liang H, Swift S, Nazli A, Kafka JK, Bramson J, Xing Z, Jordana M, Wan Y, Snider DP, Stampfli MR, Kaushic C.

PLoS Pathog. 2016 May 5;12(5):e1005589. doi: 10.1371/journal.ppat.1005589. eCollection 2016 May. Erratum in: PLoS Pathog. 2016 Jun;12(6):e1005706.

20.

Hydroxychloroquine attenuates cigarette smoke induced autophagic signaling in the mouse ovary.

Furlong HC, Wessels JM, Guerra MT, Stämpfli MR, Foster WG.

Reprod Toxicol. 2016 Jun;61:105-13. doi: 10.1016/j.reprotox.2016.03.044. Epub 2016 Mar 29.

21.

Cigarette Smoke Attenuates the Nasal Host Response to Streptococcus pneumoniae and Predisposes to Invasive Pneumococcal Disease in Mice.

Shen P, Morissette MC, Vanderstocken G, Gao Y, Hassan M, Roos A, Thayaparan D, Merlano M, Dorrington MG, Nikota JK, Bauer CMT, Kwiecien JM, Labiris R, Bowdish DME, Stevenson CS, Stämpfli MR.

Infect Immun. 2016 Apr 22;84(5):1536-1547. doi: 10.1128/IAI.01504-15. Print 2016 May.

22.

Small airway epithelial-C/EBPβ is increased in patients with advanced COPD.

Mori M, Bjermer L, Erjefält JS, Stampfli MR, Roos AB.

Respir Res. 2015 Oct 29;16:133. doi: 10.1186/s12931-015-0297-0.

23.

Cigarette smoke exposure triggers the autophagic cascade via activation of the AMPK pathway in mice.

Furlong HC, Stämpfli MR, Gannon AM, Foster WG.

Biol Reprod. 2015 Oct;93(4):93. doi: 10.1095/biolreprod.115.132183. Epub 2015 Sep 16.

24.

Disruption of pulmonary lipid homeostasis drives cigarette smoke-induced lung inflammation in mice.

Morissette MC, Shen P, Thayaparan D, Stämpfli MR.

Eur Respir J. 2015 Nov;46(5):1451-60. doi: 10.1183/09031936.00216914. Epub 2015 Jun 25.

25.

IL-17A and the Promotion of Neutrophilia in Acute Exacerbation of Chronic Obstructive Pulmonary Disease.

Roos AB, Sethi S, Nikota J, Wrona CT, Dorrington MG, Sandén C, Bauer CM, Shen P, Bowdish D, Stevenson CS, Erjefält JS, Stampfli MR.

Am J Respir Crit Care Med. 2015 Aug 15;192(4):428-37. doi: 10.1164/rccm.201409-1689OC.

PMID:
26039632
26.

IL-17A Is Elevated in End-Stage Chronic Obstructive Pulmonary Disease and Contributes to Cigarette Smoke-induced Lymphoid Neogenesis.

Roos AB, Sandén C, Mori M, Bjermer L, Stampfli MR, Erjefält JS.

Am J Respir Crit Care Med. 2015 Jun 1;191(11):1232-41. doi: 10.1164/rccm.201410-1861OC.

PMID:
25844618
27.

Influenza promotes collagen deposition via αvβ6 integrin-mediated transforming growth factor β activation.

Jolly L, Stavrou A, Vanderstoken G, Meliopoulos VA, Habgood A, Tatler AL, Porte J, Knox A, Weinreb P, Violette S, Hussell T, Kolb M, Stampfli MR, Schultz-Cherry S, Jenkins G.

J Biol Chem. 2014 Dec 19;289(51):35246-63. doi: 10.1074/jbc.M114.582262. Epub 2014 Oct 22.

28.

Cigarette smoke primes the pulmonary environment to IL-1α/CXCR-2-dependent nontypeable Haemophilus influenzae-exacerbated neutrophilia in mice.

Nikota JK, Shen P, Morissette MC, Fernandes K, Roos A, Chu DK, Barra NG, Iwakura Y, Kolbeck R, Humbles AA, Stampfli MR.

J Immunol. 2014 Sep 15;193(6):3134-45. doi: 10.4049/jimmunol.1302412. Epub 2014 Aug 4.

29.

Impacts of peroxisome proliferator-activated receptor-γ activation on cigarette smoke-induced exacerbated response to bacteria.

Morissette MC, Shen P, Thayaparan D, Stämpfli MR.

Eur Respir J. 2015 Jan;45(1):191-200. doi: 10.1183/09031936.00004314. Epub 2014 Jul 17.

30.

Persistence of pulmonary tertiary lymphoid tissues and anti-nuclear antibodies following cessation of cigarette smoke exposure.

Morissette MC, Jobse BN, Thayaparan D, Nikota JK, Shen P, Labiris NR, Kolbeck R, Nair P, Humbles AA, Stämpfli MR.

Respir Res. 2014 Apr 22;15:49. doi: 10.1186/1465-9921-15-49.

31.

Impact of inflammation, emphysema, and smoking cessation on V/Q in mouse models of lung obstruction.

Jobse BN, McCurry CA, Morissette MC, Rhem RG, Stämpfli MR, Labiris NR.

Respir Res. 2014 Apr 14;15:42. doi: 10.1186/1465-9921-15-42.

32.

Impact of cigarette smoke on the human and mouse lungs: a gene-expression comparison study.

Morissette MC, Lamontagne M, Bérubé JC, Gaschler G, Williams A, Yauk C, Couture C, Laviolette M, Hogg JC, Timens W, Halappanavar S, Stampfli MR, Bossé Y.

PLoS One. 2014 Mar 24;9(3):e92498. doi: 10.1371/journal.pone.0092498. eCollection 2014.

33.

A GM-CSF/IL-33 pathway facilitates allergic airway responses to sub-threshold house dust mite exposure.

Llop-Guevara A, Chu DK, Walker TD, Goncharova S, Fattouh R, Silver JS, Moore CL, Xie JL, O'Byrne PM, Coyle AJ, Kolbeck R, Humbles AA, Stämpfli MR, Jordana M.

PLoS One. 2014 Feb 14;9(2):e88714. doi: 10.1371/journal.pone.0088714. eCollection 2014.

34.

Alterations in skeletal muscle cell homeostasis in a mouse model of cigarette smoke exposure.

Caron MA, Morissette MC, Thériault ME, Nikota JK, Stämpfli MR, Debigaré R.

PLoS One. 2013 Jun 14;8(6):e66433. doi: 10.1371/journal.pone.0066433. Print 2013.

35.

Continuous and discontinuous cigarette smoke exposure differentially affects protective Th1 immunity against pulmonary tuberculosis.

Shaler CR, Horvath CN, McCormick S, Jeyanathan M, Khera A, Zganiacz A, Kasinska J, Stampfli MR, Xing Z.

PLoS One. 2013;8(3):e59185. doi: 10.1371/journal.pone.0059185. Epub 2013 Mar 19.

36.

Asthma associated with incontinentia pigmenti and Fanconi anemia: variable airflow limitation without cellular bronchitis.

Dasgupta A, Sanaee MS, Bauer CMT, Botelho FM, Arnold DM, Stampfli MR, Nair P.

Chest. 2013 Mar;143(3):856-858. doi: 10.1378/chest.12-0859.

PMID:
23460164
37.

Detection of lung dysfunction using ventilation and perfusion SPECT in a mouse model of chronic cigarette smoke exposure.

Jobse BN, Rhem RG, Wang IQ, Counter WB, Stämpfli MR, Labiris NR.

J Nucl Med. 2013 Apr;54(4):616-23. doi: 10.2967/jnumed.112.111419. Epub 2013 Feb 8.

38.

Cigarette smoke exposure elicits increased autophagy and dysregulation of mitochondrial dynamics in murine granulosa cells.

Gannon AM, Stämpfli MR, Foster WG.

Biol Reprod. 2013 Mar 14;88(3):63. doi: 10.1095/biolreprod.112.106617. Print 2013 Mar.

PMID:
23325812
39.

The influence of cigarette smoking on viral infections: translating bench science to impact COPD pathogenesis and acute exacerbations of COPD clinically.

Bauer CMT, Morissette MC, Stämpfli MR.

Chest. 2013 Jan;143(1):196-206. doi: 10.1378/chest.12-0930. Review.

PMID:
23276842
40.

Cigarette smoke-induced accumulation of lung dendritic cells is interleukin-1α-dependent in mice.

Botelho FM, Nikota JK, Bauer CM, Morissette MC, Iwakura Y, Kolbeck R, Finch D, Humbles AA, Stämpfli MR.

Respir Res. 2012 Sep 19;13:81. doi: 10.1186/1465-9921-13-81.

41.

Cigarette smoke-induced inflammation and respiratory host defense: Insights from animal models.

Nikota JK, Stämpfli MR.

Pulm Pharmacol Ther. 2012 Aug;25(4):257-62. doi: 10.1016/j.pupt.2012.05.005. Epub 2012 May 24. Review.

PMID:
22634304
42.

Cigarette smoke and platelet-activating factor receptor dependent adhesion of Streptococcus pneumoniae to lower airway cells.

Grigg J, Walters H, Sohal SS, Wood-Baker R, Reid DW, Xu CB, Edvinsson L, Morissette MC, Stämpfli MR, Kirwan M, Koh L, Suri R, Mushtaq N.

Thorax. 2012 Oct;67(10):908-13. doi: 10.1136/thoraxjnl-2011-200835. Epub 2012 May 1.

PMID:
22550083
43.

Shifting of immune responsiveness to house dust mite by influenza A infection: genomic insights.

Al-Garawi A, Husain M, Ilieva D, Humbles AA, Kolbeck R, Stampfli MR, O'Byrne PM, Coyle AJ, Jordana M.

J Immunol. 2012 Jan 15;188(2):832-43. doi: 10.4049/jimmunol.1102349. Epub 2011 Dec 14.

44.

IL-1α/IL-1R1 expression in chronic obstructive pulmonary disease and mechanistic relevance to smoke-induced neutrophilia in mice.

Botelho FM, Bauer CM, Finch D, Nikota JK, Zavitz CC, Kelly A, Lambert KN, Piper S, Foster ML, Goldring JJ, Wedzicha JA, Bassett J, Bramson J, Iwakura Y, Sleeman M, Kolbeck R, Coyle AJ, Humbles AA, Stämpfli MR.

PLoS One. 2011;6(12):e28457. doi: 10.1371/journal.pone.0028457. Epub 2011 Dec 6.

45.

Cigarette smoke exposure leads to follicle loss via an alternative ovarian cell death pathway in a mouse model.

Gannon AM, Stämpfli MR, Foster WG.

Toxicol Sci. 2012 Jan;125(1):274-84. doi: 10.1093/toxsci/kfr279. Epub 2011 Oct 14.

PMID:
22003194
46.

Influenza A facilitates sensitization to house dust mite in infant mice leading to an asthma phenotype in adulthood.

Al-Garawi A, Fattouh R, Botelho F, Walker TD, Goncharova S, Moore CL, Mori M, Erjefalt JS, Chu DK, Humbles AA, Kolbeck R, Stampfli MR, O'Byrne PM, Coyle AJ, Jordana M.

Mucosal Immunol. 2011 Nov;4(6):682-94. doi: 10.1038/mi.2011.35. Epub 2011 Aug 31.

PMID:
21881572
47.

Cigarette smoke exposure aggravates air space enlargement and alveolar cell apoptosis in Smad3 knockout mice.

Farkas L, Farkas D, Warburton D, Gauldie J, Shi W, Stampfli MR, Voelkel NF, Kolb M.

Am J Physiol Lung Cell Mol Physiol. 2011 Oct;301(4):L391-401. doi: 10.1152/ajplung.00369.2010. Epub 2011 Jul 8.

48.

Lung epithelial CCAAT/enhancer-binding protein-β is necessary for the integrity of inflammatory responses to cigarette smoke.

Didon L, Barton JL, Roos AB, Gaschler GJ, Bauer CM, Berg T, Stämpfli MR, Nord M.

Am J Respir Crit Care Med. 2011 Jul 15;184(2):233-42. doi: 10.1164/rccm.201007-1113OC. Epub 2011 May 11.

PMID:
21562127
49.

Differential expression and function of breast regression protein 39 (BRP-39) in murine models of subacute cigarette smoke exposure and allergic airway inflammation.

Nikota JK, Botelho FM, Bauer CM, Jordana M, Coyle AJ, Humbles AA, Stampfli MR.

Respir Res. 2011 Apr 7;12:39. doi: 10.1186/1465-9921-12-39.

50.

A mouse GM-CSF receptor antibody attenuates neutrophilia in mice exposed to cigarette smoke.

Botelho FM, Nikota JK, Bauer C, Davis NH, Cohen ES, Anderson IK, Coyle AJ, Kolbeck R, Humbles AA, Stämpfli MR, Sleeman MA.

Eur Respir J. 2011 Aug;38(2):285-94. doi: 10.1183/09031936.00076210. Epub 2011 Mar 24.

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