Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 16

1.

Thorough Performance Evaluation of 213 nm Ultraviolet Photodissociation for Top-down Proteomics.

Fornelli L, Srzentić K, Toby TK, Doubleday PF, Huguet R, Mullen C, Melani RD, Dos Santos Seckler H, DeHart CJ, Weisbrod CR, Durbin KR, Greer JB, Early BP, Fellers RT, Zabrouskov V, Thomas PM, Compton PD, Kelleher NL.

Mol Cell Proteomics. 2020 Feb;19(2):405-420. doi: 10.1074/mcp.TIR119.001638. Epub 2019 Dec 30.

PMID:
31888965
2.

Proton Transfer Charge Reduction Enables High-Throughput Top-Down Analysis of Large Proteoforms.

Huguet R, Mullen C, Srzentić K, Greer JB, Fellers RT, Zabrouskov V, Syka JEP, Kelleher NL, Fornelli L.

Anal Chem. 2019 Dec 17;91(24):15732-15739. doi: 10.1021/acs.analchem.9b03925. Epub 2019 Nov 22.

PMID:
31714757
3.

Direct measurement of light and heavy antibody chains using ion mobility and middle-down mass spectrometry.

Melani RD, Srzentić K, Gerbasi VR, McGee JP, Huguet R, Fornelli L, Kelleher NL.

MAbs. 2019 Nov-Dec;11(8):1351-1357. doi: 10.1080/19420862.2019.1668226. Epub 2019 Oct 13.

4.

Structural Analysis of Monoclonal Antibodies by Ultrahigh Resolution MALDI In-Source Decay FT-ICR Mass Spectrometry.

van der Burgt YEM, Kilgour DPA, Tsybin YO, Srzentić K, Fornelli L, Beck A, Wuhrer M, Nicolardi S.

Anal Chem. 2019 Feb 5;91(3):2079-2085. doi: 10.1021/acs.analchem.8b04515. Epub 2019 Jan 8.

5.

A comprehensive pipeline for translational top-down proteomics from a single blood draw.

Toby TK, Fornelli L, Srzentić K, DeHart CJ, Levitsky J, Friedewald J, Kelleher NL.

Nat Protoc. 2019 Jan;14(1):119-152. doi: 10.1038/s41596-018-0085-7.

6.

Multiplexed Middle-Down Mass Spectrometry as a Method for Revealing Light and Heavy Chain Connectivity in a Monoclonal Antibody.

Srzentić K, Nagornov KO, Fornelli L, Lobas AA, Ayoub D, Kozhinov AN, Gasilova N, Menin L, Beck A, Gorshkov MV, Aizikov K, Tsybin YO.

Anal Chem. 2018 Nov 6;90(21):12527-12535. doi: 10.1021/acs.analchem.8b02398. Epub 2018 Oct 12.

PMID:
30252447
7.

Accurate Sequence Analysis of a Monoclonal Antibody by Top-Down and Middle-Down Orbitrap Mass Spectrometry Applying Multiple Ion Activation Techniques.

Fornelli L, Srzentić K, Huguet R, Mullen C, Sharma S, Zabrouskov V, Fellers RT, Durbin KR, Compton PD, Kelleher NL.

Anal Chem. 2018 Jul 17;90(14):8421-8429. doi: 10.1021/acs.analchem.8b00984. Epub 2018 Jun 28.

8.

Chemical-Mediated Digestion: An Alternative Realm for Middle-down Proteomics?

Srzentić K, Zhurov KO, Lobas AA, Nikitin G, Fornelli L, Gorshkov MV, Tsybin YO.

J Proteome Res. 2018 Jun 1;17(6):2005-2016. doi: 10.1021/acs.jproteome.7b00834. Epub 2018 May 18.

PMID:
29722266
9.

Top-down characterization of endogenous protein complexes with native proteomics.

Skinner OS, Haverland NA, Fornelli L, Melani RD, Do Vale LHF, Seckler HS, Doubleday PF, Schachner LF, Srzentić K, Kelleher NL, Compton PD.

Nat Chem Biol. 2018 Jan;14(1):36-41. doi: 10.1038/nchembio.2515. Epub 2017 Nov 13.

10.

Monitoring Membrane Lipidome Turnover by Metabolic 15N Labeling and Shotgun Ultra-High-Resolution Orbitrap Fourier Transform Mass Spectrometry.

Schuhmann K, Srzentić K, Nagornov KO, Thomas H, Gutmann T, Coskun Ü, Tsybin YO, Shevchenko A.

Anal Chem. 2017 Dec 5;89(23):12857-12865. doi: 10.1021/acs.analchem.7b03437. Epub 2017 Nov 22.

PMID:
29111682
11.

Top-down proteomics: Where we are, where we are going?

Fornelli L, Toby TK, Schachner LF, Doubleday PF, Srzentić K, DeHart CJ, Kelleher NL.

J Proteomics. 2018 Mar 20;175:3-4. doi: 10.1016/j.jprot.2017.02.002. Epub 2017 Feb 7. No abstract available.

12.

On-Chip Mesoporous Functionalized Magnetic Microspheres for Protein Sequencing by Extended Bottom-up Mass Spectrometry.

Gasilova N, Srzentić K, Qiao L, Liu B, Beck A, Tsybin YO, Girault HH.

Anal Chem. 2016 Feb 2;88(3):1775-84. doi: 10.1021/acs.analchem.5b04045. Epub 2016 Jan 8.

PMID:
26708268
13.

Advantages of extended bottom-up proteomics using Sap9 for analysis of monoclonal antibodies.

Srzentić K, Fornelli L, Laskay ÜA, Monod M, Beck A, Ayoub D, Tsybin YO.

Anal Chem. 2014 Oct 7;86(19):9945-53. doi: 10.1021/ac502766n. Epub 2014 Sep 24.

PMID:
25207962
14.

Extended bottom-up proteomics with secreted aspartic protease Sap9.

Laskay ÜA, Srzentić K, Monod M, Tsybin YO.

J Proteomics. 2014 Oct 14;110:20-31. doi: 10.1016/j.jprot.2014.07.035. Epub 2014 Aug 11.

PMID:
25123351
15.

Proteome digestion specificity analysis for rational design of extended bottom-up and middle-down proteomics experiments.

Laskay ÜA, Lobas AA, Srzentić K, Gorshkov MV, Tsybin YO.

J Proteome Res. 2013 Dec 6;12(12):5558-69. doi: 10.1021/pr400522h. Epub 2013 Oct 30.

PMID:
24171472
16.

Practical considerations for improving the productivity of mass spectrometry-based proteomics.

Laskay UA, Srzentić K, Fornelli L, Upir O, Kozhinov AN, Monod M, Tsybin YO.

Chimia (Aarau). 2013;67(4):244-9.

PMID:
23967698

Supplemental Content

Loading ...
Support Center