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Items: 1 to 50 of 156

1.

Aging negatively impacts the ability of megakaryocytes to stimulate osteoblast proliferation and bone mass.

Maupin KA, Himes ER, Plett AP, Chua HL, Singh P, Ghosh J, Mohamad SF, Abeysekera I, Fisher A, Sampson C, Hong JM, Childress P, Alvarez M, Srour EF, Bruzzaniti A, Pelus LM, Orschell CM, Kacena MA.

Bone. 2019 Oct;127:452-459. doi: 10.1016/j.bone.2019.07.010. Epub 2019 Jul 9.

PMID:
31299382
2.

CD166 Engagement Augments Mouse and Human Hematopoietic Progenitor Function via Activation of Stemness and Cell Cycle Pathways.

Zhang J, Ghosh J, Mohamad SF, Zhang C, Huang X, Capitano ML, Gunawan AM, Cooper S, Guo B, Cai Q, Broxmeyer HE, Srour EF.

Stem Cells. 2019 Oct;37(10):1319-1330. doi: 10.1002/stem.3053. Epub 2019 Aug 14.

PMID:
31260147
3.

Absence of Cardiomyocyte Differentiation Following Transplantation of Adult Cardiac-Resident Sca-1+ Cells Into Infarcted Mouse Hearts.

Soonpaa MH, Lafontant PJ, Reuter S, Scherschel JA, Srour EF, Zaruba MM, Rubart-von der Lohe M, Field LJ.

Circulation. 2018 Dec 18;138(25):2963-2966. doi: 10.1161/CIRCULATIONAHA.118.035391. No abstract available.

PMID:
30566013
4.

Isolation and Identification of Murine Bone Marrow-Derived Macrophages and Osteomacs from Neonatal and Adult Mice.

Ghosh J, Mohamad SF, Srour EF.

Methods Mol Biol. 2019;2002:181-193. doi: 10.1007/7651_2018_196.

PMID:
30539348
5.

Megakaryocyte and Osteoblast Interactions Modulate Bone Mass and Hematopoiesis.

Alvarez MB, Xu L, Childress PJ, Maupin KA, Mohamad SF, Chitteti BR, Himes E, Olivos DJ 3rd, Cheng YH, Conway SJ, Srour EF, Kacena MA.

Stem Cells Dev. 2018 May 15;27(10):671-682. doi: 10.1089/scd.2017.0178.

6.

Osteomacs interact with megakaryocytes and osteoblasts to regulate murine hematopoietic stem cell function.

Mohamad SF, Xu L, Ghosh J, Childress PJ, Abeysekera I, Himes ER, Wu H, Alvarez MB, Davis KM, Aguilar-Perez A, Hong JM, Bruzzaniti A, Kacena MA, Srour EF.

Blood Adv. 2017 Dec 5;1(26):2520-2528. doi: 10.1182/bloodadvances.2017011304. eCollection 2017 Dec 12.

7.

Tamm-Horsfall Protein Regulates Mononuclear Phagocytes in the Kidney.

Micanovic R, Khan S, Janosevic D, Lee ME, Hato T, Srour EF, Winfree S, Ghosh J, Tong Y, Rice SE, Dagher PC, Wu XR, El-Achkar TM.

J Am Soc Nephrol. 2018 Mar;29(3):841-856. doi: 10.1681/ASN.2017040409. Epub 2017 Nov 27.

8.

Erythropoietin stimulates murine and human fibroblast growth factor-23, revealing novel roles for bone and bone marrow.

Clinkenbeard EL, Hanudel MR, Stayrook KR, Appaiah HN, Farrow EG, Cass TA, Summers LJ, Ip CS, Hum JM, Thomas JC, Ivan M, Richine BM, Chan RJ, Clemens TL, Schipani E, Sabbagh Y, Xu L, Srour EF, Alvarez MB, Kacena MA, Salusky IB, Ganz T, Nemeth E, White KE.

Haematologica. 2017 Nov;102(11):e427-e430. doi: 10.3324/haematol.2017.167882. Epub 2017 Aug 17. No abstract available.

9.

Individualized Breast Cancer Characterization through Single-Cell Analysis of Tumor and Adjacent Normal Cells.

Anjanappa M, Cardoso A, Cheng L, Mohamad S, Gunawan A, Rice S, Dong Y, Li L, Sandusky GE, Srour EF, Nakshatri H.

Cancer Res. 2017 May 15;77(10):2759-2769. doi: 10.1158/0008-5472.CAN-16-3308. Epub 2017 Mar 1.

10.

p190-B RhoGAP and intracellular cytokine signals balance hematopoietic stem and progenitor cell self-renewal and differentiation.

Hinge A, Xu J, Javier J, Mose E, Kumar S, Kapur R, Srour EF, Malik P, Aronow BJ, Filippi MD.

Nat Commun. 2017 Feb 8;8:14382. doi: 10.1038/ncomms14382.

11.

Lnk Deficiency Leads to TPO-Mediated Osteoclastogenesis and Increased Bone Mass Phenotype.

Olivos DJ 3rd, Alvarez M, Cheng YH, Hooker RA, Ciovacco WA, Bethel M, McGough H, Yim C, Chitteti BR, Eleniste PP, Horowitz MC, Srour EF, Bruzzaniti A, Fuchs RK, Kacena MA.

J Cell Biochem. 2017 Aug;118(8):2231-2240. doi: 10.1002/jcb.25874. Epub 2017 Apr 18.

12.

Cell Adhesion Molecule CD166 Drives Malignant Progression and Osteolytic Disease in Multiple Myeloma.

Xu L, Mohammad KS, Wu H, Crean C, Poteat B, Cheng Y, Cardoso AA, Machal C, Hanenberg H, Abonour R, Kacena MA, Chirgwin J, Suvannasankha A, Srour EF.

Cancer Res. 2016 Dec 1;76(23):6901-6910. Epub 2016 Sep 7.

13.

Proximity-Based Differential Single-Cell Analysis of the Niche to Identify Stem/Progenitor Cell Regulators.

Silberstein L, Goncalves KA, Kharchenko PV, Turcotte R, Kfoury Y, Mercier F, Baryawno N, Severe N, Bachand J, Spencer JA, Papazian A, Lee D, Chitteti BR, Srour EF, Hoggatt J, Tate T, Lo Celso C, Ono N, Nutt S, Heino J, Sipilä K, Shioda T, Osawa M, Lin CP, Hu GF, Scadden DT.

Cell Stem Cell. 2016 Oct 6;19(4):530-543. doi: 10.1016/j.stem.2016.07.004. Epub 2016 Aug 11.

14.

C-Mpl Is Expressed on Osteoblasts and Osteoclasts and Is Important in Regulating Skeletal Homeostasis.

Meijome TE, Baughman JT, Hooker RA, Cheng YH, Ciovacco WA, Balamohan SM, Srinivasan TL, Chitteti BR, Eleniste PP, Horowitz MC, Srour EF, Bruzzaniti A, Fuchs RK, Kacena MA.

J Cell Biochem. 2016 Apr;117(4):959-69. doi: 10.1002/jcb.25380. Epub 2015 Oct 6.

15.

Modulation of hematopoietic progenitor cell fate in vitro by varying collagen oligomer matrix stiffness in the presence or absence of osteoblasts.

Chitteti BR, Kacena MA, Voytik-Harbin SL, Srour EF.

J Immunol Methods. 2015 Oct;425:108-113. doi: 10.1016/j.jim.2015.07.001. Epub 2015 Jul 6.

PMID:
26159389
16.

Enhancing Hematopoietic Stem Cell Transplantation Efficacy by Mitigating Oxygen Shock.

Mantel CR, O'Leary HA, Chitteti BR, Huang X, Cooper S, Hangoc G, Brustovetsky N, Srour EF, Lee MR, Messina-Graham S, Haas DM, Falah N, Kapur R, Pelus LM, Bardeesy N, Fitamant J, Ivan M, Kim KS, Broxmeyer HE.

Cell. 2015 Jun 18;161(7):1553-65. doi: 10.1016/j.cell.2015.04.054. Epub 2015 Jun 11.

17.

Ames hypopituitary dwarf mice demonstrate imbalanced myelopoiesis between bone marrow and spleen.

Capitano ML, Chitteti BR, Cooper S, Srour EF, Bartke A, Broxmeyer HE.

Blood Cells Mol Dis. 2015 Jun;55(1):15-20. doi: 10.1016/j.bcmd.2015.03.004. Epub 2015 Mar 28.

18.

Expansion of prostate epithelial progenitor cells after inflammation of the mouse prostate.

Wang L, Zoetemelk M, Chitteti BR, Ratliff TL, Myers JD, Srour EF, Broxmeyer H, Jerde TJ.

Am J Physiol Renal Physiol. 2015 Jun 15;308(12):F1421-30. doi: 10.1152/ajprenal.00488.2014. Epub 2015 Apr 29.

19.

Activated leukocyte cell adhesion molecule (ALCAM or CD166) modulates bone phenotype and hematopoiesis.

Hooker RA, Chitteti BR, Egan PH, Cheng YH, Himes ER, Meijome T, Srour EF, Fuchs RK, Kacena MA.

J Musculoskelet Neuronal Interact. 2015 Mar;15(1):83-94.

20.

A novel role for thrombopoietin in regulating osteoclast development in humans and mice.

Bethel M, Barnes CL, Taylor AF, Cheng YH, Chitteti BR, Horowitz MC, Bruzzaniti A, Srour EF, Kacena MA.

J Cell Physiol. 2015 Sep;230(9):2142-51. doi: 10.1002/jcp.24943.

21.

Pak2 regulates hematopoietic progenitor cell proliferation, survival, and differentiation.

Zeng Y, Broxmeyer HE, Staser K, Chitteti BR, Park SJ, Hahn S, Cooper S, Sun Z, Jiang L, Yang X, Yuan J, Kosoff R, Sandusky G, Srour EF, Chernoff J, Clapp DW.

Stem Cells. 2015 May;33(5):1630-41. doi: 10.1002/stem.1951.

22.

Tamm-Horsfall Protein Regulates Granulopoiesis and Systemic Neutrophil Homeostasis.

Micanovic R, Chitteti BR, Dagher PC, Srour EF, Khan S, Hato T, Lyle A, Tong Y, Wu XR, El-Achkar TM.

J Am Soc Nephrol. 2015 Sep;26(9):2172-82. doi: 10.1681/ASN.2014070664. Epub 2015 Jan 2.

23.

Human adipose-derived stem cells ameliorate cigarette smoke-induced murine myelosuppression via secretion of TSG-6.

Xie J, Broxmeyer HE, Feng D, Schweitzer KS, Yi R, Cook TG, Chitteti BR, Barwinska D, Traktuev DO, Van Demark MJ, Justice MJ, Ou X, Srour EF, Prockop DJ, Petrache I, March KL.

Stem Cells. 2015 Feb;33(2):468-78. doi: 10.1002/stem.1851.

24.

Signaling pathways involved in megakaryocyte-mediated proliferation of osteoblast lineage cells.

Cheng YH, Streicher DA, Waning DL, Chitteti BR, Gerard-O'Riley R, Horowitz MC, Bidwell JP, Pavalko FM, Srour EF, Mayo LD, Kacena MA.

J Cell Physiol. 2015 Mar;230(3):578-86. doi: 10.1002/jcp.24774.

25.

Cell cycle measurement of mouse hematopoietic stem/progenitor cells.

Chitteti BR, Srour EF.

Methods Mol Biol. 2014;1185:65-78. doi: 10.1007/978-1-4939-1133-2_5.

PMID:
25062622
26.

Notch-dependent repression of miR-155 in the bone marrow niche regulates hematopoiesis in an NF-κB-dependent manner.

Wang L, Zhang H, Rodriguez S, Cao L, Parish J, Mumaw C, Zollman A, Kamoka MM, Mu J, Chen DZ, Srour EF, Chitteti BR, HogenEsch H, Tu X, Bellido TM, Boswell HS, Manshouri T, Verstovsek S, Yoder MC, Kapur R, Cardoso AA, Carlesso N.

Cell Stem Cell. 2014 Jul 3;15(1):51-65. doi: 10.1016/j.stem.2014.04.021.

27.

Nonmarrow hematopoiesis occurs in a hyaluronic-acid-rich node and duct system in mice.

Hwang S, Lee SJ, Park SH, Chitteti BR, Srour EF, Cooper S, Hangoc G, Broxmeyer HE, Kwon BS.

Stem Cells Dev. 2014 Nov 1;23(21):2661-71. doi: 10.1089/scd.2014.0075. Epub 2014 Jul 14.

28.

CD166 regulates human and murine hematopoietic stem cells and the hematopoietic niche.

Chitteti BR, Kobayashi M, Cheng Y, Zhang H, Poteat BA, Broxmeyer HE, Pelus LM, Hanenberg H, Zollman A, Kamocka MM, Carlesso N, Cardoso AA, Kacena MA, Srour EF.

Blood. 2014 Jul 24;124(4):519-29. doi: 10.1182/blood-2014-03-565721. Epub 2014 Apr 16.

29.

In vitro construction of 2D and 3D simulations of the murine hematopoietic niche.

Chitteti BR, Bethel M, Voytik-Harbin SL, Kacena MA, Srour EF.

Methods Mol Biol. 2013;1035:43-56. doi: 10.1007/978-1-62703-508-8_5.

PMID:
23959981
30.

CD166 and regulation of hematopoiesis.

Chitteti BR, Bethel M, Kacena MA, Srour EF.

Curr Opin Hematol. 2013 Jul;20(4):273-80. doi: 10.1097/MOH.0b013e32836060a9. Review.

PMID:
23615053
31.

Differential stem- and progenitor-cell trafficking by prostaglandin E2.

Hoggatt J, Mohammad KS, Singh P, Hoggatt AF, Chitteti BR, Speth JM, Hu P, Poteat BA, Stilger KN, Ferraro F, Silberstein L, Wong FK, Farag SS, Czader M, Milne GL, Breyer RM, Serezani CH, Scadden DT, Guise TA, Srour EF, Pelus LM.

Nature. 2013 Mar 21;495(7441):365-9. doi: 10.1038/nature11929. Epub 2013 Mar 13.

32.

The changing balance between osteoblastogenesis and adipogenesis in aging and its impact on hematopoiesis.

Bethel M, Chitteti BR, Srour EF, Kacena MA.

Curr Osteoporos Rep. 2013 Jun;11(2):99-106. doi: 10.1007/s11914-013-0135-6. Review.

33.

Hierarchical organization of osteoblasts reveals the significant role of CD166 in hematopoietic stem cell maintenance and function.

Chitteti BR, Cheng YH, Kacena MA, Srour EF.

Bone. 2013 May;54(1):58-67. doi: 10.1016/j.bone.2013.01.038. Epub 2013 Jan 28.

34.

Pyk2 regulates megakaryocyte-induced increases in osteoblast number and bone formation.

Cheng YH, Hooker RA, Nguyen K, Gerard-O'Riley R, Waning DL, Chitteti BR, Meijome TE, Chua HL, Plett AP, Orschell CM, Srour EF, Mayo LD, Pavalko FM, Bruzzaniti A, Kacena MA.

J Bone Miner Res. 2013 Jun;28(6):1434-45. doi: 10.1002/jbmr.1876.

35.

Dipeptidylpeptidase 4 negatively regulates colony-stimulating factor activity and stress hematopoiesis.

Broxmeyer HE, Hoggatt J, O'Leary HA, Mantel C, Chitteti BR, Cooper S, Messina-Graham S, Hangoc G, Farag S, Rohrabaugh SL, Ou X, Speth J, Pelus LM, Srour EF, Campbell TB.

Nat Med. 2012 Dec;18(12):1786-96. doi: 10.1038/nm.2991. Epub 2012 Nov 18.

36.

Regulation of murine hematopoietic stem cell quiescence by Dmtf1.

Kobayashi M, Srour EF.

Blood. 2011 Dec 15;118(25):6562-71. doi: 10.1182/blood-2011-05-349084. Epub 2011 Oct 28.

37.

Angiopoietin-like-2 and -3 act through their coiled-coil domains to enhance survival and replating capacity of human cord blood hematopoietic progenitors.

Broxmeyer HE, Srour EF, Cooper S, Wallace CT, Hangoc G, Youn BS.

Blood Cells Mol Dis. 2012 Jan 15;48(1):25-9. doi: 10.1016/j.bcmd.2011.09.004. Epub 2011 Oct 7.

38.

Impact of maturational status on the ability of osteoblasts to enhance the hematopoietic function of stem and progenitor cells.

Cheng YH, Chitteti BR, Streicher DA, Morgan JA, Rodriguez-Rodriguez S, Carlesso N, Srour EF, Kacena MA.

J Bone Miner Res. 2011 May;26(5):1111-21. doi: 10.1002/jbmr.302.

39.

The SKP2 E3 ligase regulates basal homeostasis and stress-induced regeneration of HSCs.

Rodriguez S, Wang L, Mumaw C, Srour EF, Lo Celso C, Nakayama K, Carlesso N.

Blood. 2011 Jun 16;117(24):6509-19. doi: 10.1182/blood-2010-11-321521. Epub 2011 Apr 18.

40.

Genomic and proteomic analysis of the impact of mitotic quiescence on the engraftment of human CD34+ cells.

Chitteti BR, Liu Y, Srour EF.

PLoS One. 2011 Mar 7;6(3):e17498. doi: 10.1371/journal.pone.0017498.

41.

Wnt signaling promotes neuronal differentiation from mesenchymal stem cells through activation of Tlx3.

Kondo T, Matsuoka AJ, Shimomura A, Koehler KR, Chan RJ, Miller JM, Srour EF, Hashino E.

Stem Cells. 2011 May;29(5):836-46. doi: 10.1002/stem.624.

42.

Hematopoietic cell regulation of osteoblast proliferation and differentiation.

Bethel M, Srour EF, Kacena MA.

Curr Osteoporos Rep. 2011 Jun;9(2):96-102. doi: 10.1007/s11914-011-0048-1. Review.

43.

CCR7 alters hematopoietic potential.

Srour EF.

Blood. 2010 Dec 9;116(24):5086-7. doi: 10.1182/blood-2010-09-307801. No abstract available.

PMID:
21148339
44.

Antibody targeting KIT as pretransplantation conditioning in immunocompetent mice.

Xue X, Pech NK, Shelley WC, Srour EF, Yoder MC, Dinauer MC.

Blood. 2010 Dec 9;116(24):5419-22. doi: 10.1182/blood-2010-07-295949. Epub 2010 Sep 2.

45.

Application of polychromatic flow cytometry to identify novel subsets of circulating cells with angiogenic potential.

Estes ML, Mund JA, Mead LE, Prater DN, Cai S, Wang H, Pollok KE, Murphy MP, An CS, Srour EF, Ingram DA Jr, Case J.

Cytometry A. 2010 Sep;77(9):831-9. doi: 10.1002/cyto.a.20921.

46.

SLUG/SNAI2 and tumor necrosis factor generate breast cells with CD44+/CD24- phenotype.

Bhat-Nakshatri P, Appaiah H, Ballas C, Pick-Franke P, Goulet R Jr, Badve S, Srour EF, Nakshatri H.

BMC Cancer. 2010 Aug 6;10:411. doi: 10.1186/1471-2407-10-411.

47.

Osteoblast lineage cells expressing high levels of Runx2 enhance hematopoietic progenitor cell proliferation and function.

Chitteti BR, Cheng YH, Streicher DA, Rodriguez-Rodriguez S, Carlesso N, Srour EF, Kacena MA.

J Cell Biochem. 2010 Oct 1;111(2):284-94. doi: 10.1002/jcb.22694.

48.

Impact of interactions of cellular components of the bone marrow microenvironment on hematopoietic stem and progenitor cell function.

Chitteti BR, Cheng YH, Poteat B, Rodriguez-Rodriguez S, Goebel WS, Carlesso N, Kacena MA, Srour EF.

Blood. 2010 Apr 22;115(16):3239-48. doi: 10.1182/blood-2009-09-246173. Epub 2010 Feb 12.

49.

Loss of the Rho GTPase activating protein p190-B enhances hematopoietic stem cell engraftment potential.

Xu H, Eleswarapu S, Geiger H, Szczur K, Daria D, Zheng Y, Settleman J, Srour EF, Williams DA, Filippi MD.

Blood. 2009 Oct 22;114(17):3557-66. doi: 10.1182/blood-2009-02-205815. Epub 2009 Aug 27.

50.

Estradiol-regulated microRNAs control estradiol response in breast cancer cells.

Bhat-Nakshatri P, Wang G, Collins NR, Thomson MJ, Geistlinger TR, Carroll JS, Brown M, Hammond S, Srour EF, Liu Y, Nakshatri H.

Nucleic Acids Res. 2009 Aug;37(14):4850-61. doi: 10.1093/nar/gkp500. Epub 2009 Jun 14.

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