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Items: 1 to 50 of 132

1.

The Emergence of Successful Streptococcus pyogenes Lineages through Convergent Pathways of Capsule Loss and Recombination Directing High Toxin Expression.

Turner CE, Holden MTG, Blane B, Horner C, Peacock SJ, Sriskandan S.

mBio. 2019 Dec 10;10(6). pii: e02521-19. doi: 10.1128/mBio.02521-19.

2.

A multi-species cluster of GES-5 carbapenemase producing Enterobacterales linked by a geographically disseminated plasmid.

Ellington MJ, Davies F, Jauneikaite E, Hopkins KL, Turton JF, Adams G, Pavlu J, Innes AJ, Eades C, Brannigan ET, Findlay J, White L, Bolt F, Kadhani T, Chow Y, Patel B, Mookerjee S, Otter JA, Sriskandan S, Woodford N, Holmes A.

Clin Infect Dis. 2019 Nov 20. pii: ciz1130. doi: 10.1093/cid/ciz1130. [Epub ahead of print]

PMID:
31746994
3.

Hospital clusters of invasive Group B Streptococcal disease: A systematic review.

Collin SM, Lamb P, Jauneikaite E, Le Doare K, Creti R, Berardi A, Heath PT, Sriskandan S, Lamagni T.

J Infect. 2019 Dec;79(6):521-527. doi: 10.1016/j.jinf.2019.11.008. Epub 2019 Nov 13.

4.

Sepsis: Precision-Based Medicine for Pregnancy and the Puerperium.

Greer O, Shah NM, Sriskandan S, Johnson MR.

Int J Mol Sci. 2019 Oct 29;20(21). pii: E5388. doi: 10.3390/ijms20215388. Review.

5.

Toxic Shock Syndrome Toxin 1 Evaluation and Antibiotic Impact in a Transgenic Model of Staphylococcal Soft Tissue Infection.

Sharma H, Turner CE, Siggins MK, El-Bahrawy M, Pichon B, Kearns A, Sriskandan S.

mSphere. 2019 Oct 9;4(5). pii: e00665-19. doi: 10.1128/mSphere.00665-19.

6.

Emergence of dominant toxigenic M1T1 Streptococcus pyogenes clone during increased scarlet fever activity in England: a population-based molecular epidemiological study.

Lynskey NN, Jauneikaite E, Li HK, Zhi X, Turner CE, Mosavie M, Pearson M, Asai M, Lobkowicz L, Chow JY, Parkhill J, Lamagni T, Chalker VJ, Sriskandan S.

Lancet Infect Dis. 2019 Nov;19(11):1209-1218. doi: 10.1016/S1473-3099(19)30446-3. Epub 2019 Sep 10.

7.

Elevated risk of invasive group A streptococcal disease and host genetic variation in the human leucocyte antigen locus.

Parks T, Elliott K, Lamagni T, Auckland K, Mentzer AJ, Guy R, Cartledge D, Strakova L, Connor DO, Pollard AJ, Neville MJ, Mahajan A, Ashrafian H, Chapman SJ, Hill AVS, Sriskandan S, Knight JC.

Genes Immun. 2020 Jan;21(1):63-70. doi: 10.1038/s41435-019-0082-z. Epub 2019 Aug 29.

8.

Staphylococcus aureus colonization and acquisition of skin and soft tissue infection among Royal Marines recruits: a prospective cohort study.

Jauneikaite E, Ferguson T, Mosavie M, Fallowfield JL, Davey T, Thorpe N, Allsopp A, Shaw AM, Fudge D, O'Shea MK, Wilson D, Morgan M, Pichon B, Kearns AM, Sriskandan S, Lamb LE.

Clin Microbiol Infect. 2020 Mar;26(3):381.e1-381.e6. doi: 10.1016/j.cmi.2019.07.014. Epub 2019 Jul 26.

PMID:
31357012
9.

Two-year analysis of Clostridium difficile ribotypes associated with increased severity.

Herbert R, Hatcher J, Jauneikaite E, Gharbi M, d'Arc S, Obaray N, Rickards T, Rebec M, Blandy O, Hope R, Thomas A, Bamford K, Jepson A, Sriskandan S.

J Hosp Infect. 2019 Dec;103(4):388-394. doi: 10.1016/j.jhin.2019.06.003. Epub 2019 Jun 18.

10.

Sampling and diversity of Escherichia coli from the enteric microbiota in patients with Escherichia coli bacteraemia.

Mosavie M, Blandy O, Jauneikaite E, Caldas I, Ellington MJ, Woodford N, Sriskandan S.

BMC Res Notes. 2019 Jun 13;12(1):335. doi: 10.1186/s13104-019-4369-y.

11.

A Requirement for Neutrophil Glycosaminoglycans in Chemokine:Receptor Interactions Is Revealed by the Streptococcal Protease SpyCEP.

Goldblatt J, Lawrenson RA, Muir L, Dattani S, Hoffland A, Tsuchiya T, Kanegasaki S, Sriskandan S, Pease JE.

J Immunol. 2019 Jun 1;202(11):3246-3255. doi: 10.4049/jimmunol.1801688. Epub 2019 Apr 22.

12.

Treatment potential of pathogen-reactive antibodies sequentially purified from pooled human immunoglobulin.

Reglinski M, Sriskandan S.

BMC Res Notes. 2019 Apr 15;12(1):228. doi: 10.1186/s13104-019-4262-8.

13.

Streptococcal superantigen-induced expansion of human tonsil T cells leads to altered T follicular helper cell phenotype, B cell death and reduced immunoglobulin release.

Davies FJ, Olme C, Lynskey NN, Turner CE, Sriskandan S.

Clin Exp Immunol. 2019 Jul;197(1):83-94. doi: 10.1111/cei.13282. Epub 2019 Mar 13.

14.

Identification of two new core chromosome-encoded superantigens in Streptococcus pyogenes; speQ and speR.

Reglinski M, Sriskandan S, Turner CE.

J Infect. 2019 May;78(5):358-363. doi: 10.1016/j.jinf.2019.02.005. Epub 2019 Feb 20.

15.

Supervised machine learning for the prediction of infection on admission to hospital: a prospective observational cohort study.

Rawson TM, Hernandez B, Moore LSP, Blandy O, Herrero P, Gilchrist M, Gordon A, Toumazou C, Sriskandan S, Georgiou P, Holmes AH.

J Antimicrob Chemother. 2019 Apr 1;74(4):1108-1115. doi: 10.1093/jac/dky514.

16.

Factors that impact on the burden of Escherichia coli bacteraemia: multivariable regression analysis of 2011-2015 data from West London.

Blandy O, Honeyford K, Gharbi M, Thomas A, Ramzan F, Ellington MJ, Hope R, Holmes AH, Johnson AP, Aylin P, Woodford N, Sriskandan S.

J Hosp Infect. 2019 Feb;101(2):120-128. doi: 10.1016/j.jhin.2018.10.024. Epub 2018 Nov 4.

17.

Cohort study protocol: Bioresource in Adult Infectious Diseases (BioAID).

Shallcross LJ, Mentzer A, Rahman S, Cooke GS, Sriskandan S, Noursadeghi M.

Wellcome Open Res. 2018 Aug 8;3:97. doi: 10.12688/wellcomeopenres.14690.1. eCollection 2018.

18.

Familial Transmission of emm12 Group A Streptococcus.

Mearkle R, Balasegaram S, Sriskandan S, Chalker V, Lamagni T.

Emerg Infect Dis. 2018 Nov;24(11):2133-2134. doi: 10.3201/eid2411.171743. No abstract available.

19.

Severe group A streptococcal infections in mothers and their newborns in London and the South East, 2010-2016: assessment of risk and audit of public health management.

Leonard A, Wright A, Saavedra-Campos M, Lamagni T, Cordery R, Nicholls M, Domoney C, Sriskandan S, Balasegaram S.

BJOG. 2019 Jan;126(1):44-53. doi: 10.1111/1471-0528.15415. Epub 2018 Sep 9.

20.

Impact of contusion injury on intramuscular emm1 group a streptococcus infection and lymphatic spread.

Lamb LE, Siggins MK, Scudamore C, Macdonald W, Turner CE, Lynskey NN, Tan LKK, Sriskandan S.

Virulence. 2018;9(1):1074-1084. doi: 10.1080/21505594.2018.1482180.

21.

Modelling invasive group A streptococcal disease using bioluminescence.

Lamb LE, Zhi X, Alam F, Pyzio M, Scudamore CL, Wiles S, Sriskandan S.

BMC Microbiol. 2018 Jun 19;18(1):60. doi: 10.1186/s12866-018-1200-1.

22.

Polyspecific Intravenous Immunoglobulin in Clindamycin-treated Patients With Streptococcal Toxic Shock Syndrome: A Systematic Review and Meta-analysis.

Parks T, Wilson C, Curtis N, Norrby-Teglund A, Sriskandan S.

Clin Infect Dis. 2018 Oct 15;67(9):1434-1436. doi: 10.1093/cid/ciy401.

23.

Development of an opsonophagocytic killing assay for group a streptococcus.

Jones S, Moreland NJ, Zancolli M, Raynes J, Loh JMS, Smeesters PR, Sriskandan S, Carapetis JR, Fraser JD, Goldblatt D.

Vaccine. 2018 Jun 18;36(26):3756-3763. doi: 10.1016/j.vaccine.2018.05.056.

24.

Proteomic analysis at the sites of clinical infection with invasive Streptococcus pyogenes.

Edwards RJ, Pyzio M, Gierula M, Turner CE, Abdul-Salam VB, Sriskandan S.

Sci Rep. 2018 Apr 13;8(1):5950. doi: 10.1038/s41598-018-24216-2.

25.

High prevalence of 16S rRNA methyltransferases among carbapenemase-producing Enterobacteriaceae in the UK and Ireland.

Taylor E, Sriskandan S, Woodford N, Hopkins KL.

Int J Antimicrob Agents. 2018 Aug;52(2):278-282. doi: 10.1016/j.ijantimicag.2018.03.016. Epub 2018 Mar 27.

26.

Serial Clustering of Late-Onset Group B Streptococcal Infections in the Neonatal Unit: A Genomic Re-evaluation of Causality.

Jauneikaite E, Kapatai G, Davies F, Gozar I, Coelho J, Bamford KB, Simone B, Begum L, Katiyo S, Patel B, Hoffman P, Lamagni T, Brannigan ET, Holmes AH, Kadhani T, Galletly T, Martin K, Lyall H, Chow Y, Godambe S, Chalker V, Sriskandan S.

Clin Infect Dis. 2018 Aug 31;67(6):854-860. doi: 10.1093/cid/ciy174.

27.

Clinical and Molecular Epidemiology of Staphylococcal Toxic Shock Syndrome in the United Kingdom.

Sharma H, Smith D, Turner CE, Game L, Pichon B, Hope R, Hill R, Kearns A, Sriskandan S.

Emerg Infect Dis. 2018 Feb;24(2). doi: 10.3201/eid2402.170606.

28.

Multi-functional mechanisms of immune evasion by the streptococcal complement inhibitor C5a peptidase.

Lynskey NN, Reglinski M, Calay D, Siggins MK, Mason JC, Botto M, Sriskandan S.

PLoS Pathog. 2017 Aug 14;13(8):e1006493. doi: 10.1371/journal.ppat.1006493. eCollection 2017 Aug.

29.

Household transmission of invasive group A Streptococcus infections in England: a population-based study, 2009, 2011 to 2013.

Mearkle R, Saavedra-Campos M, Lamagni T, Usdin M, Coelho J, Chalker V, Sriskandan S, Cordery R, Rawlings C, Balasegaram S.

Euro Surveill. 2017 May 11;22(19). pii: 30532. doi: 10.2807/1560-7917.ES.2017.22.19.30532.

30.

Enhanced nasopharyngeal infection and shedding associated with an epidemic lineage of emm3 group A Streptococcus.

Afshar B, Turner CE, Lamagni TL, Smith KC, Al-Shahib A, Underwood A, Holden MTG, Efstratiou A, Sriskandan S.

Virulence. 2017 Oct 3;8(7):1390-1400. doi: 10.1080/21505594.2017.1325070. Epub 2017 May 1.

31.

Corrigendum: Emergence of a novel lineage containing a prophage in emm/M3 group A Streptococcus associated with upsurge in invasive disease in the UK.

Al-Shahib A, Underwood A, Afshar B, Turner CE, Lamagni T, Sriskandan S, Efstratiou A.

Microb Genom. 2016 Nov 30;2(11):e000097. doi: 10.1099/mgen.0.000097. eCollection 2016 Nov.

32.

Emergence of a novel lineage containing a prophage in emm/M3 group A Streptococcus associated with upsurge in invasive disease in the UK.

Al-Shahib A, Underwood A, Afshar B, Turner CE, Lamagni T, Sriskandan S, Efstratiou A.

Microb Genom. 2016 Jun 24;2(6):e000059. doi: 10.1099/mgen.0.000059. eCollection 2016 Jun. Erratum in: Microb Genom. 2016 Nov 30;2(11):e000097.

33.

Identification of commonly expressed exoproteins and proteolytic cleavage events by proteomic mining of clinically relevant UK isolates of Staphylococcus aureus.

Smith DS, Siggins MK, Gierula M, Pichon B, Turner CE, Lynskey NN, Mosavie M, Kearns AM, Edwards RJ, Sriskandan S.

Microb Genom. 2016 Feb 23;2(2):e000049. doi: 10.1099/mgen.0.000049. eCollection 2016 Feb.

34.

Asymptomatic group A Streptococcal throat carriage in Royal Marines recruits and Young Officers.

Pearson M, Fallowfield JL, Davey T, Thorpe NM, Allsopp AJ, Shaw A, Wilson DR, Sriskandan S, Lamb LE.

J Infect. 2017 Jun;74(6):585-589. doi: 10.1016/j.jinf.2017.03.001. Epub 2017 Mar 23.

35.

Nosocomial Outbreak of Drug-Resistant Streptococcus pneumoniae Serotype 9V in an Adult Respiratory Medicine Ward.

Jauneikaite E, Khan-Orakzai Z, Kapatai G, Bloch S, Singleton J, Atkin S, Shah V, Hatcher J, Samarasinghe D, Sheppard C, Fry NK, Satta G, Sriskandan S.

J Clin Microbiol. 2017 Mar;55(3):776-782. doi: 10.1128/JCM.02405-16. Epub 2016 Dec 14.

36.

Scarlet Fever Upsurge in England and Molecular-Genetic Analysis in North-West London, 2014.

Turner CE, Pyzio M, Song B, Lamagni T, Meltzer M, Chow JY, Efstratiou A, Curtis S, Sriskandan S.

Emerg Infect Dis. 2016 Jun;22(6):1075-8. doi: 10.3201/eid2206.151726.

37.

Modification of the classical Lancefield assay of group A streptococcal killing to reduce inter-donor variation.

Reglinski M, Lynskey NN, Sriskandan S.

J Microbiol Methods. 2016 May;124:69-71. doi: 10.1016/j.mimet.2016.03.015. Epub 2016 Mar 24.

38.

Development of a multicomponent vaccine for Streptococcus pyogenes based on the antigenic targets of IVIG.

Reglinski M, Lynskey NN, Choi YJ, Edwards RJ, Sriskandan S.

J Infect. 2016 Apr;72(4):450-9. doi: 10.1016/j.jinf.2016.02.002. Epub 2016 Feb 12.

39.

Turner et al. Reply to "Emergence of the Same Successful Clade among Distinct Populations of emm89 Streptococcus pyogenes in Multiple Geographic Regions".

Turner CE, Lamagni T, Holden MT, David S, Jones MD, Game L, Efstratiou A, Sriskandan S.

mBio. 2015 Dec 1;6(6):e01883-15. doi: 10.1128/mBio.01883-15. No abstract available.

40.

Identification of the Streptococcus pyogenes surface antigens recognised by pooled human immunoglobulin.

Reglinski M, Gierula M, Lynskey NN, Edwards RJ, Sriskandan S.

Sci Rep. 2015 Oct 28;5:15825. doi: 10.1038/srep15825.

41.

Rapid Lymphatic Dissemination of Encapsulated Group A Streptococci via Lymphatic Vessel Endothelial Receptor-1 Interaction.

Lynskey NN, Banerji S, Johnson LA, Holder KA, Reglinski M, Wing PA, Rigby D, Jackson DG, Sriskandan S.

PLoS Pathog. 2015 Sep 9;11(9):e1005137. doi: 10.1371/journal.ppat.1005137. eCollection 2015 Sep.

42.

The effect of trauma on invasive group A streptococcal disease.

Lamb L, McDonald W, Scudamore C, Tan L, Lynskey N, Sriskandan S.

Lancet. 2015 Feb 26;385 Suppl 1:S60. doi: 10.1016/S0140-6736(15)60375-0.

PMID:
26312882
43.

Corynebacterium ulcerans cutaneous diphtheria.

Moore LSP, Leslie A, Meltzer M, Sandison A, Efstratiou A, Sriskandan S.

Lancet Infect Dis. 2015 Sep;15(9):1100-1107. doi: 10.1016/S1473-3099(15)00225-X. Epub 2015 Jul 16. Review.

44.

Emergence of a New Highly Successful Acapsular Group A Streptococcus Clade of Genotype emm89 in the United Kingdom.

Turner CE, Abbott J, Lamagni T, Holden MT, David S, Jones MD, Game L, Efstratiou A, Sriskandan S.

mBio. 2015 Jul 14;6(4):e00622. doi: 10.1128/mBio.00622-15.

45.

Panton-Valentine leucocidin expression by Staphylococcus aureus exposed to common antibiotics.

Turner CE, Sriskandan S.

J Infect. 2015 Sep;71(3):338-46. doi: 10.1016/j.jinf.2015.05.008. Epub 2015 May 28.

46.

A truncation in the regulator RocA underlies heightened capsule expression in serotype M3 group A streptococci.

Lynskey NN, Turner CE, Heng LS, Sriskandan S.

Infect Immun. 2015 Apr;83(4):1732-3. doi: 10.1128/IAI.02892-14. No abstract available.

47.

Bromine, bear-claw scratch fasciotomies, and the Eagle effect: management of group A streptococcal necrotising fasciitis and its association with trauma.

Lamb LE, Sriskandan S, Tan LK.

Lancet Infect Dis. 2015 Jan;15(1):109-21. doi: 10.1016/S1473-3099(14)70922-3. Review.

48.

The cost of hospital care for management of invasive group A streptococcal infections in England.

Hughes GJ, VAN Hoek AJ, Sriskandan S, Lamagni TL.

Epidemiol Infect. 2015 Jun;143(8):1719-30. doi: 10.1017/S0950268814002489. Epub 2014 Sep 29.

49.

Ebola and other viral haemorrhagic fevers: a local operational approach.

Moore LS, Moore M, Sriskandan S.

Br J Hosp Med (Lond). 2014 Sep;75(9):515-22. doi: 10.12968/hmed.2014.75.9.515. Review. No abstract available.

50.

Working towards a group A streptococcal vaccine: report of a collaborative Trans-Tasman workshop.

Moreland NJ, Waddington CS, Williamson DA, Sriskandan S, Smeesters PR, Proft T, Steer AC, Walker MJ, Baker EN, Baker MG, Lennon D, Dunbar R, Carapetis J, Fraser JD.

Vaccine. 2014 Jun 24;32(30):3713-20. doi: 10.1016/j.vaccine.2014.05.017. Epub 2014 May 14.

PMID:
24837510

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