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Items: 48

1.

MYC Regulation of D2HGDH and L2HGDH Influences the Epigenome and Epitranscriptome.

Qiu Z, Lin AP, Jiang S, Elkashef SM, Myers J, Srikantan S, Sasi B, Cao JZ, Godley LA, Rakheja D, Lyu Y, Zheng S, Madesh M, Shiio Y, Dahia PLM, Aguiar RCT.

Cell Chem Biol. 2020 Feb 24. pii: S2451-9456(20)30040-4. doi: 10.1016/j.chembiol.2020.02.002. [Epub ahead of print]

PMID:
32101699
2.

The tumor suppressor TMEM127 regulates insulin sensitivity in a tissue-specific manner.

Srikantan S, Deng Y, Cheng ZM, Luo A, Qin Y, Gao Q, Sande-Docor GM, Tao S, Zhang X, Harper N, Shannon CE, Fourcaudot M, Li Z, Kasinath BS, Harrison S, Ahuja S, Reddick RL, Dong LQ, Abdul-Ghani M, Norton L, Aguiar RCT, Dahia PLM.

Nat Commun. 2019 Oct 17;10(1):4720. doi: 10.1038/s41467-019-12661-0.

3.

Blockade of MCU-Mediated Ca2+ Uptake Perturbs Lipid Metabolism via PP4-Dependent AMPK Dephosphorylation.

Tomar D, Jaña F, Dong Z, Quinn WJ 3rd, Jadiya P, Breves SL, Daw CC, Srikantan S, Shanmughapriya S, Nemani N, Carvalho E, Tripathi A, Worth AM, Zhang X, Razmpour R, Seelam A, Rhode S, Mehta AV, Murray M, Slade D, Ramirez SH, Mishra P, Gerhard GS, Caplan J, Norton L, Sharma K, Rajan S, Balciunas D, Wijesinghe DS, Ahima RS, Baur JA, Madesh M.

Cell Rep. 2019 Mar 26;26(13):3709-3725.e7. doi: 10.1016/j.celrep.2019.02.107.

4.

A Selective and Cell-Permeable Mitochondrial Calcium Uniporter (MCU) Inhibitor Preserves Mitochondrial Bioenergetics after Hypoxia/Reoxygenation Injury.

Woods JJ, Nemani N, Shanmughapriya S, Kumar A, Zhang M, Nathan SR, Thomas M, Carvalho E, Ramachandran K, Srikantan S, Stathopulos PB, Wilson JJ, Madesh M.

ACS Cent Sci. 2019 Jan 23;5(1):153-166. doi: 10.1021/acscentsci.8b00773. Epub 2019 Jan 4.

5.

The TMEM127 human tumor suppressor is a component of the mTORC1 lysosomal nutrient-sensing complex.

Deng Y, Qin Y, Srikantan S, Luo A, Cheng ZM, Flores SK, Vogel KS, Wang E, Dahia PLM.

Hum Mol Genet. 2018 May 15;27(10):1794-1808. doi: 10.1093/hmg/ddy095.

6.

PAR-CLIP analysis uncovers AUF1 impact on target RNA fate and genome integrity.

Yoon JH, De S, Srikantan S, Abdelmohsen K, Grammatikakis I, Kim J, Kim KM, Noh JH, White EJ, Martindale JL, Yang X, Kang MJ, Wood WH 3rd, Noren Hooten N, Evans MK, Becker KG, Tripathi V, Prasanth KV, Wilson GM, Tuschl T, Ingolia NT, Hafner M, Gorospe M.

Nat Commun. 2014 Nov 4;5:5248. doi: 10.1038/ncomms6248.

7.

The tumor susceptibility gene TMEM127 is mutated in renal cell carcinomas and modulates endolysosomal function.

Qin Y, Deng Y, Ricketts CJ, Srikantan S, Wang E, Maher ER, Dahia PL.

Hum Mol Genet. 2014 May 1;23(9):2428-39. doi: 10.1093/hmg/ddt638. Epub 2013 Dec 13.

8.

Tyrosine phosphorylation of HuR by JAK3 triggers dissociation and degradation of HuR target mRNAs.

Yoon JH, Abdelmohsen K, Srikantan S, Guo R, Yang X, Martindale JL, Gorospe M.

Nucleic Acids Res. 2014 Jan;42(2):1196-208. doi: 10.1093/nar/gkt903. Epub 2013 Oct 7.

9.

Top3β is an RNA topoisomerase that works with fragile X syndrome protein to promote synapse formation.

Xu D, Shen W, Guo R, Xue Y, Peng W, Sima J, Yang J, Sharov A, Srikantan S, Yang J, Fox D 3rd, Qian Y, Martindale JL, Piao Y, Machamer J, Joshi SR, Mohanty S, Shaw AC, Lloyd TE, Brown GW, Ko MS, Gorospe M, Zou S, Wang W.

Nat Neurosci. 2013 Sep;16(9):1238-47. doi: 10.1038/nn.3479. Epub 2013 Aug 4.

10.

In vivo and in vitro oncogenic effects of HIF2A mutations in pheochromocytomas and paragangliomas.

Toledo RA, Qin Y, Srikantan S, Morales NP, Li Q, Deng Y, Kim SW, Pereira MA, Toledo SP, Su X, Aguiar RC, Dahia PL.

Endocr Relat Cancer. 2013 May 21;20(3):349-59. doi: 10.1530/ERC-13-0101. Print 2013 Jun.

11.

Copious urinary excretion of a male Syrian hamster (Mesocricetus auratus) salivary gland protein after its endocrine-like release upon β-adrenergic stimulation.

Dubey VP, Srikantan S, Mohammad MP, Rajan WD, De PK.

Gen Comp Endocrinol. 2013 Jun 1;186:25-32. doi: 10.1016/j.ygcen.2013.02.016. Epub 2013 Feb 27.

PMID:
23453961
12.

RNA-binding protein AUF1 represses Dicer expression.

Abdelmohsen K, Tominaga-Yamanaka K, Srikantan S, Yoon JH, Kang MJ, Gorospe M.

Nucleic Acids Res. 2012 Dec;40(22):11531-44. doi: 10.1093/nar/gks930. Epub 2012 Oct 11.

13.

LincRNA-p21 suppresses target mRNA translation.

Yoon JH, Abdelmohsen K, Srikantan S, Yang X, Martindale JL, De S, Huarte M, Zhan M, Becker KG, Gorospe M.

Mol Cell. 2012 Aug 24;47(4):648-55. doi: 10.1016/j.molcel.2012.06.027. Epub 2012 Jul 26. Erratum in: Mol Cell. 2013 Apr 25;50(2):303.

14.

MS2-TRAP (MS2-tagged RNA affinity purification): tagging RNA to identify associated miRNAs.

Yoon JH, Srikantan S, Gorospe M.

Methods. 2012 Oct;58(2):81-7. doi: 10.1016/j.ymeth.2012.07.004. Epub 2012 Jul 17.

15.

Functional interplay between RNA-binding protein HuR and microRNAs.

Srikantan S, Tominaga K, Gorospe M.

Curr Protein Pept Sci. 2012 Jun;13(4):372-9. Review.

16.

Growth inhibition by miR-519 via multiple p21-inducing pathways.

Abdelmohsen K, Srikantan S, Tominaga K, Kang MJ, Yaniv Y, Martindale JL, Yang X, Park SS, Becker KG, Subramanian M, Maudsley S, Lal A, Gorospe M.

Mol Cell Biol. 2012 Jul;32(13):2530-48. doi: 10.1128/MCB.00510-12. Epub 2012 Apr 30.

17.

Regulation of senescence by microRNA biogenesis factors.

Abdelmohsen K, Srikantan S, Kang MJ, Gorospe M.

Ageing Res Rev. 2012 Sep;11(4):491-500. doi: 10.1016/j.arr.2012.01.003. Epub 2012 Jan 28. Review.

18.

HuR function in disease.

Srikantan S, Gorospe M.

Front Biosci (Landmark Ed). 2012 Jan 1;17:189-205. Review.

19.

Senescence-associated microRNAs linked to tumorigenesis.

Srikantan S, Gorospe M, Abdelmohsen K.

Cell Cycle. 2011 Oct 1;10(19):3211-2. doi: 10.4161/cc.10.19.17050. Epub 2011 Oct 1. No abstract available.

20.

Competitive regulation of nucleolin expression by HuR and miR-494.

Tominaga K, Srikantan S, Lee EK, Subaran SS, Martindale JL, Abdelmohsen K, Gorospe M.

Mol Cell Biol. 2011 Oct;31(20):4219-31. doi: 10.1128/MCB.05955-11. Epub 2011 Aug 22.

21.

UneCLIPsing HuR nuclear function.

Srikantan S, Gorospe M.

Mol Cell. 2011 Aug 5;43(3):319-21. doi: 10.1016/j.molcel.2011.07.016.

22.

Altered glycobiology of stem cells linked to age-related osteoarthritis.

Srikantan S, Gorospe M.

Aging (Albany NY). 2011 Jul;3(7):663-4.

23.

Translational control of TOP2A influences doxorubicin efficacy.

Srikantan S, Abdelmohsen K, Lee EK, Tominaga K, Subaran SS, Kuwano Y, Kulshrestha R, Panchakshari R, Kim HH, Yang X, Martindale JL, Marasa BS, Kim MM, Wersto RP, Indig FE, Chowdhury D, Gorospe M.

Mol Cell Biol. 2011 Sep;31(18):3790-801. doi: 10.1128/MCB.05639-11. Epub 2011 Jul 18.

24.

Enhanced translation by Nucleolin via G-rich elements in coding and non-coding regions of target mRNAs.

Abdelmohsen K, Tominaga K, Lee EK, Srikantan S, Kang MJ, Kim MM, Selimyan R, Martindale JL, Yang X, Carrier F, Zhan M, Becker KG, Gorospe M.

Nucleic Acids Res. 2011 Oct;39(19):8513-30. doi: 10.1093/nar/gkr488. Epub 2011 Jul 6.

25.

Global dissociation of HuR-mRNA complexes promotes cell survival after ionizing radiation.

Masuda K, Abdelmohsen K, Kim MM, Srikantan S, Lee EK, Tominaga K, Selimyan R, Martindale JL, Yang X, Lehrmann E, Zhang Y, Becker KG, Wang JY, Kim HH, Gorospe M.

EMBO J. 2011 Mar 16;30(6):1040-53. doi: 10.1038/emboj.2011.24. Epub 2011 Feb 11.

26.

Paradoxical microRNAs: individual gene repressors, global translation enhancers.

Srikantan S, Marasa BS, Becker KG, Gorospe M, Abdelmohsen K.

Cell Cycle. 2011 Mar 1;10(5):751-9. Epub 2011 Mar 1.

27.

miR-130 suppresses adipogenesis by inhibiting peroxisome proliferator-activated receptor gamma expression.

Lee EK, Lee MJ, Abdelmohsen K, Kim W, Kim MM, Srikantan S, Martindale JL, Hutchison ER, Kim HH, Marasa BS, Selimyan R, Egan JM, Smith SR, Fried SK, Gorospe M.

Mol Cell Biol. 2011 Feb;31(4):626-38. doi: 10.1128/MCB.00894-10. Epub 2010 Dec 6.

28.

MicroRNA profiling in human diploid fibroblasts uncovers miR-519 role in replicative senescence.

Marasa BS, Srikantan S, Martindale JL, Kim MM, Lee EK, Gorospe M, Abdelmohsen K.

Aging (Albany NY). 2010 Jun;2(6):333-43.

29.

miR-375 inhibits differentiation of neurites by lowering HuD levels.

Abdelmohsen K, Hutchison ER, Lee EK, Kuwano Y, Kim MM, Masuda K, Srikantan S, Subaran SS, Marasa BS, Mattson MP, Gorospe M.

Mol Cell Biol. 2010 Sep;30(17):4197-210. doi: 10.1128/MCB.00316-10. Epub 2010 Jun 28.

30.

hnRNP C promotes APP translation by competing with FMRP for APP mRNA recruitment to P bodies.

Lee EK, Kim HH, Kuwano Y, Abdelmohsen K, Srikantan S, Subaran SS, Gleichmann M, Mughal MR, Martindale JL, Yang X, Worley PF, Mattson MP, Gorospe M.

Nat Struct Mol Biol. 2010 Jun;17(6):732-9. doi: 10.1038/nsmb.1815. Epub 2010 May 16.

31.

Cloning, overexpression, purification, crystallization and preliminary X-ray analysis of a female-specific lipocalin (FLP) expressed in the lacrimal glands of Syrian hamsters.

Dubey VP, Pal B, Srikantan S, Pottabathini S, De PK, Sankaranarayanan R.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 May 1;66(Pt 5):509-12. doi: 10.1107/S1744309110008237. Epub 2010 Apr 29.

32.

miR-519 suppresses tumor growth by reducing HuR levels.

Abdelmohsen K, Kim MM, Srikantan S, Mercken EM, Brennan SE, Wilson GM, Cabo Rd, Gorospe M.

Cell Cycle. 2010 Apr 1;9(7):1354-9. Epub 2010 Apr 1.

33.

Increased MKK4 abundance with replicative senescence is linked to the joint reduction of multiple microRNAs.

Marasa BS, Srikantan S, Masuda K, Abdelmohsen K, Kuwano Y, Yang X, Martindale JL, Rinker-Schaeffer CW, Gorospe M.

Sci Signal. 2009 Oct 27;2(94):ra69. doi: 10.1126/scisignal.2000442.

34.

HuR recruits let-7/RISC to repress c-Myc expression.

Kim HH, Kuwano Y, Srikantan S, Lee EK, Martindale JL, Gorospe M.

Genes Dev. 2009 Aug 1;23(15):1743-8. doi: 10.1101/gad.1812509. Epub 2009 Jul 2.

35.

Ubiquitin-mediated proteolysis of HuR by heat shock.

Abdelmohsen K, Srikantan S, Yang X, Lal A, Kim HH, Kuwano Y, Galban S, Becker KG, Kamara D, de Cabo R, Gorospe M.

EMBO J. 2009 May 6;28(9):1271-82. doi: 10.1038/emboj.2009.67. Epub 2009 Mar 26.

36.

Analysis of nitric oxide-stabilized mRNAs in human fibroblasts reveals HuR-dependent heme oxygenase 1 upregulation.

Kuwano Y, Rabinovic A, Srikantan S, Gorospe M, Demple B.

Mol Cell Biol. 2009 May;29(10):2622-35. doi: 10.1128/MCB.01495-08. Epub 2009 Mar 16.

37.

The RNA-binding protein HuR regulates DNA methylation through stabilization of DNMT3b mRNA.

López de Silanes I, Gorospe M, Taniguchi H, Abdelmohsen K, Srikantan S, Alaminos M, Berdasco M, Urdinguio RG, Fraga MF, Jacinto FV, Esteller M.

Nucleic Acids Res. 2009 May;37(8):2658-71. doi: 10.1093/nar/gkp123. Epub 2009 Mar 6.

38.

miR-519 reduces cell proliferation by lowering RNA-binding protein HuR levels.

Abdelmohsen K, Srikantan S, Kuwano Y, Gorospe M.

Proc Natl Acad Sci U S A. 2008 Dec 23;105(51):20297-302. doi: 10.1073/pnas.0809376106. Epub 2008 Dec 16.

39.

Sex differences in expression and differential regulation by androgen and estrogen of two odorant-binding tear lipocalins in lacrimal glands of immature hamsters.

Srikantan S, De PK.

Gen Comp Endocrinol. 2008 Sep 15;158(3):268-76. doi: 10.1016/j.ygcen.2008.07.019. Epub 2008 Aug 6.

PMID:
18703064
40.

Post-transcriptional gene regulation by HuR promotes a more tumorigenic phenotype.

Mazan-Mamczarz K, Hagner PR, Corl S, Srikantan S, Wood WH, Becker KG, Gorospe M, Keene JD, Levenson AS, Gartenhaus RB.

Oncogene. 2008 Oct 16;27(47):6151-63. doi: 10.1038/onc.2008.215. Epub 2008 Jul 21.

41.

Nuclear HuR accumulation through phosphorylation by Cdk1.

Kim HH, Abdelmohsen K, Lal A, Pullmann R Jr, Yang X, Galban S, Srikantan S, Martindale JL, Blethrow J, Shokat KM, Gorospe M.

Genes Dev. 2008 Jul 1;22(13):1804-15. doi: 10.1101/gad.1645808.

42.

p16(INK4a) translation suppressed by miR-24.

Lal A, Kim HH, Abdelmohsen K, Kuwano Y, Pullmann R Jr, Srikantan S, Subrahmanyam R, Martindale JL, Yang X, Ahmed F, Navarro F, Dykxhoorn D, Lieberman J, Gorospe M.

PLoS One. 2008 Mar 26;3(3):e1864. doi: 10.1371/journal.pone.0001864.

43.

Posttranscriptional regulation of IL-13 in T cells: role of the RNA-binding protein HuR.

Casolaro V, Fang X, Tancowny B, Fan J, Wu F, Srikantan S, Asaki SY, De Fanis U, Huang SK, Gorospe M, Atasoy UX, Stellato C.

J Allergy Clin Immunol. 2008 Apr;121(4):853-9.e4. doi: 10.1016/j.jaci.2007.12.1166. Epub 2008 Feb 14.

44.

The voice advisory manikin (VAM): an innovative approach to pediatric lay provider basic life support skill education.

Sutton RM, Donoghue A, Myklebust H, Srikantan S, Byrne A, Priest M, Zoltani Z, Helfaer MA, Nadkarni V.

Resuscitation. 2007 Oct;75(1):161-8. Epub 2007 Apr 25.

PMID:
17459561
45.

Estrogen and androgen repression of two female specific lacrimal lipocalins in hamster: Pituitary independent and sex hormone receptor mediated action.

Srikantan S, Paliwal A, Quintanar-Stephano A, De PK.

Gen Comp Endocrinol. 2007 Apr;151(2):172-9. Epub 2007 Jan 19.

PMID:
17316636
46.

Histological and biochemical characterization of von Ebner's glands in the Syrian hamster; comparison with rat von Ebner's glands.

Paliwal A, Srikantan S, De PK, Hand AR, Redman RS.

Biotech Histochem. 2006 Jul-Dec;81(4-6):139-49.

PMID:
17129997
47.
48.

Effect of one-rescuer compression/ventilation ratios on cardiopulmonary resuscitation in infant, pediatric, and adult manikins.

Srikantan SK, Berg RA, Cox T, Tice L, Nadkarni VM.

Pediatr Crit Care Med. 2005 May;6(3):293-7.

PMID:
15857527

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