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Items: 1 to 50 of 153

1.

Revealing Clusters of Connected Pathways through Multisource Data Integration in Huntington's disease and Spastic Ataxia.

Kakouri A, Christodoulou C, Zachariou M, Oulas A, Minadakis G, Demetriou C, Votsi C, Papanicolaou-Zamba E, Kyproula C, Spyrou G.

IEEE J Biomed Health Inform. 2018 Aug 30. doi: 10.1109/JBHI.2018.2865569. [Epub ahead of print]

PMID:
30176611
2.

PathwayConnector: finding complementary pathways to enhance functional analysis.

Minadakis G, Zachariou M, Oulas A, Spyrou GM.

Bioinformatics. 2018 Aug 14. doi: 10.1093/bioinformatics/bty693. [Epub ahead of print]

PMID:
30124768
3.

Integrating multi-source information on a single network to detect disease-related clusters of molecular mechanisms.

Zachariou M, Minadakis G, Oulas A, Afxenti S, Spyrou GM.

J Proteomics. 2018 Sep 30;188:15-29. doi: 10.1016/j.jprot.2018.03.009. Epub 2018 Mar 13.

4.

In early arthritis patients, high HAQ at baseline and DAS28 at three months predict suboptimal outcomes at two years: a retrospective cohort study.

Fanouriakis A, Papalopoulos I, Gergianaki I, Spyrou G, Erden A, Rapsomaniki P, Terizaki M, Avgoustidis N, Repa A, Kougkas N, Bertsias G, Boumpas DT, Sidiropoulos PI.

Clin Exp Rheumatol. 2018 Feb 28. [Epub ahead of print]

PMID:
29533750
5.

18F-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomographic Imaging Detects Aortic Wall Inflammation in Patients With Repaired Coarctation of Aorta.

Brili S, Oikonomou E, Antonopoulos AS, Pianou N, Georgakopoulos A, Koutagiar I, Kafouris P, Stroumpouli E, Dounis C, Metaxas M, Spyrou G, Anagnostopoulos CD, Tousoulis D.

Circ Cardiovasc Imaging. 2018 Jan;11(1):e007002. doi: 10.1161/CIRCIMAGING.117.007002. No abstract available.

PMID:
29321213
6.

Lymphocytes eject interferogenic mitochondrial DNA webs in response to CpG and non-CpG oligodeoxynucleotides of class C.

Ingelsson B, Söderberg D, Strid T, Söderberg A, Bergh AC, Loitto V, Lotfi K, Segelmark M, Spyrou G, Rosén A.

Proc Natl Acad Sci U S A. 2018 Jan 16;115(3):E478-E487. doi: 10.1073/pnas.1711950115. Epub 2018 Jan 2.

7.

Computational profiling of the gut-brain axis: microflora dysbiosis insights to neurological disorders.

Dovrolis N, Kolios G, Spyrou GM, Maroulakou I.

Brief Bioinform. 2017 Nov 27. doi: 10.1093/bib/bbx154. [Epub ahead of print]

PMID:
29186317
8.

Systems Bioinformatics: increasing precision of computational diagnostics and therapeutics through network-based approaches.

Oulas A, Minadakis G, Zachariou M, Sokratous K, Bourdakou MM, Spyrou GM.

Brief Bioinform. 2017 Nov 27. doi: 10.1093/bib/bbx151. [Epub ahead of print]

PMID:
29186305
9.

Vascular inflammation and metabolic activity in hematopoietic organs and liver in familial combined hyperlipidemia and heterozygous familial hypercholesterolemia.

Toutouzas K, Skoumas J, Koutagiar I, Benetos G, Pianou N, Georgakopoulos A, Galanakos S, Antonopoulos A, Drakopoulou M, Oikonomou EK, Kafouris P, Athanasiadis E, Metaxas M, Spyrou G, Pallantza Z, Galiatsatos N, Aggeli C, Antoniades C, Keramida G, Peters AM, Anagnostopoulos CD, Tousoulis D.

J Clin Lipidol. 2018 Jan - Feb;12(1):33-43. doi: 10.1016/j.jacl.2017.10.019. Epub 2017 Nov 2.

PMID:
29174439
10.

Informed walks: whispering hints to gene hunters inside networks' jungle.

Bourdakou MM, Spyrou GM.

BMC Syst Biol. 2017 Oct 11;11(1):97. doi: 10.1186/s12918-017-0473-6.

11.

Drug repurposing in idiopathic pulmonary fibrosis filtered by a bioinformatics-derived composite score.

Karatzas E, Bourdakou MM, Kolios G, Spyrou GM.

Sci Rep. 2017 Oct 3;7(1):12569. doi: 10.1038/s41598-017-12849-8.

12.

Breast implant associated anaplastic large cell lymphoma: The UK experience. Recommendations on its management and implications for informed consent.

Johnson L, O'Donoghue JM, McLean N, Turton P, Khan AA, Turner SD, Lennard A, Collis N, Butterworth M, Gui G, Bristol J, Hurren J, Smith S, Grover K, Spyrou G, Krupa K, Azmy IA, Young IE, Staiano JJ, Khalil H, MacNeill FA.

Eur J Surg Oncol. 2017 Aug;43(8):1393-1401. doi: 10.1016/j.ejso.2017.05.004. Epub 2017 May 18.

PMID:
28596034
13.

Automatic cumulative sums contour detection of FBP-reconstructed multi-object nuclear medicine images.

Protonotarios NE, Spyrou GM, Kastis GA.

Comput Biol Med. 2017 Jun 1;85:43-52. doi: 10.1016/j.compbiomed.2017.04.010. Epub 2017 Apr 14.

PMID:
28433871
14.

Laying in silico pipelines for drug repositioning: a paradigm in ensemble analysis for neurodegenerative diseases.

Dovrolis N, Kolios G, Spyrou G, Maroulakou I.

Drug Discov Today. 2017 May;22(5):805-813. doi: 10.1016/j.drudis.2017.03.009. Epub 2017 Mar 29. Review.

PMID:
28363518
15.

Inflamed human carotid plaques evaluated by PET/CT exhibit increased temperature: insights from an in vivo study.

Toutouzas K, Koutagiar I, Benetos G, Aggeli C, Georgakopoulos A, Athanasiadis E, Pianou N, Trachanellis S, Patelis N, Agrogiannis G, Kafouris P, Filis K, Bessias N, Klonaris C, Spyrou G, Tsiamis E, Siores E, Patsouris E, Cokkinos D, Tousoulis D, Anagnostopoulos CD.

Eur Heart J Cardiovasc Imaging. 2017 Nov 1;18(11):1236-1244. doi: 10.1093/ehjci/jew219.

PMID:
28011672
16.

SPNsim: A database of simulated solitary pulmonary nodule PET/CT images facilitating computer aided diagnosis.

Tzanoukos G, Athanasiadis E, Gaitanis A, Georgakopoulos A, Chatziioannou A, Chatziioannou S, Spyrou G.

J Biomed Inform. 2016 Oct;63:357-365. doi: 10.1016/j.jbi.2016.09.005. Epub 2016 Sep 10.

17.

Aberrant microRNA expression in tumor mycosis fungoides.

Papadavid E, Braoudaki M, Bourdakou M, Lykoudi A, Nikolaou V, Tounta G, Ekonomidi A, Athanasiadis E, Spyrou G, Antoniou C, Kitsiou-Tzeli S, Rigopoulos D, Kolialexi A.

Tumour Biol. 2016 Nov;37(11):14667-14675. Epub 2016 Sep 13.

PMID:
27623940
18.

Prediction of Melanoma Risk in a Southern European Population Based on a Weighted Genetic Risk Score.

Kypreou KP, Stefanaki I, Antonopoulou K, Karagianni F, Ntritsos G, Zaras A, Nikolaou V, Kalfa I, Chasapi V, Polydorou D, Gogas H, Spyrou GM, Bertram L, Lill CM, Ioannidis JP, Antoniou C, Evangelou E, Stratigos AI.

J Invest Dermatol. 2016 Mar;136(3):690-5. doi: 10.1016/j.jid.2015.12.007. Epub 2015 Dec 14.

19.

D-Map: Random Walking on Gene Network Inference Maps Towards differential Avenue Discovery.

Athanasiadis E, Bourdakou M, Spyrou G.

IEEE/ACM Trans Comput Biol Bioinform. 2017 Mar-Apr;14(2):484-490. doi: 10.1109/TCBB.2016.2535267. Epub 2016 Feb 26.

PMID:
26930690
20.

KENeV: A web-application for the automated reconstruction and visualization of the enriched metabolic and signaling super-pathways deriving from genomic experiments.

Pilalis E, Koutsandreas T, Valavanis I, Athanasiadis E, Spyrou G, Chatziioannou A.

Comput Struct Biotechnol J. 2015 Apr 9;13:248-55. doi: 10.1016/j.csbj.2015.03.009. eCollection 2015.

21.
22.

The expression and activity of thioredoxin reductase 1 splice variants v1 and v2 regulate the expression of genes associated with differentiation and adhesion.

Nalvarte I, Damdimopoulos AE, Rüegg J, Spyrou G.

Biosci Rep. 2015 Oct 13;35(6). pii: e00269. doi: 10.1042/BSR20150236.

23.

ZoomOut: Analyzing Multiple Networks as Single Nodes.

Athanasiadis EI, Bourdakou MM, Spyrou GM.

IEEE/ACM Trans Comput Biol Bioinform. 2015 Sep-Oct;12(5):1213-6. doi: 10.1109/TCBB.2015.2424411.

PMID:
26451833
24.

Combination of autologous chondrocyte implantation (ACI) and osteochondral autograft transfer system (OATS) for surgical repair of larger cartilage defects of the knee joint. A review illustrated by a case report.

Duif C, Koutah MA, Ackermann O, Spyrou G, von Engelhardt LV, Kaya D, Willburger RE, Lahner M.

Technol Health Care. 2015;23(5):531-7. doi: 10.3233/THC-151003. Review.

PMID:
26410114
25.

mAPKL: R/ Bioconductor package for detecting gene exemplars and revealing their characteristics.

Sakellariou A, Spyrou G.

BMC Bioinformatics. 2015 Sep 15;16:291. doi: 10.1186/s12859-015-0719-5.

26.

Bioinformatics methods in drug repurposing for Alzheimer's disease.

Siavelis JC, Bourdakou MM, Athanasiadis EI, Spyrou GM, Nikita KS.

Brief Bioinform. 2016 Mar;17(2):322-35. doi: 10.1093/bib/bbv048. Epub 2015 Jul 21.

PMID:
26197808
27.

GeneStoryTeller: a mobile app for quick and comprehensive information retrieval of human genes.

Eleftheriou SV, Bourdakou MM, Athanasiadis EI, Spyrou GM.

Database (Oxford). 2015 Jun 8;2015:bav048. doi: 10.1093/database/bav048. Print 2015.

28.

Does intraoperative application of leukocyte-poor platelet-rich plasma during arthroscopy for knee degeneration affect postoperative pain, function and quality of life? A 12-month randomized controlled double-blind trial.

Duif C, Vogel T, Topcuoglu F, Spyrou G, von Schulze Pellengahr C, Lahner M.

Arch Orthop Trauma Surg. 2015 Jul;135(7):971-7. doi: 10.1007/s00402-015-2227-5. Epub 2015 May 10.

PMID:
25957981
29.

Updated field synopsis and systematic meta-analyses of genetic association studies in cutaneous melanoma: the MelGene database.

Antonopoulou K, Stefanaki I, Lill CM, Chatzinasiou F, Kypreou KP, Karagianni F, Athanasiadis E, Spyrou GM, Ioannidis JPA, Bertram L, Evangelou E, Stratigos AJ.

J Invest Dermatol. 2015 Apr;135(4):1074-1079. doi: 10.1038/jid.2014.491. Epub 2014 Nov 19.

30.

A Web-based database of genetic association studies in cutaneous melanoma enhanced with network-driven data exploration tools.

Athanasiadis EI, Antonopoulou K, Chatzinasiou F, Lill CM, Bourdakou MM, Sakellariou A, Kypreou K, Stefanaki I, Evangelou E, Ioannidis JP, Bertram L, Stratigos AJ, Spyrou GM.

Database (Oxford). 2014 Nov 7;2014. pii: bau101. doi: 10.1093/database/bau101. Print 2014.

31.

Structure-based virtual screening for drug discovery: principles, applications and recent advances.

Lionta E, Spyrou G, Vassilatis DK, Cournia Z.

Curr Top Med Chem. 2014;14(16):1923-38. Review.

32.

A CADx scheme for mammography empowered with topological information from clustered microcalcifications' atlases.

Andreadis II, Spyrou GM, Nikita KS.

IEEE J Biomed Health Inform. 2015 Jan;19(1):166-73.

PMID:
25073178
33.

C-PAmP: large scale analysis and database construction containing high scoring computationally predicted antimicrobial peptides for all the available plant species.

Niarchou A, Alexandridou A, Athanasiadis E, Spyrou G.

PLoS One. 2013 Nov 11;8(11):e79728. doi: 10.1371/journal.pone.0079728. eCollection 2013.

34.

Painful vaso-occlusive crisis as a prodromal phase of acute chest syndrome. Is only one chest X-ray enough? A case report.

Neocleous C, Spanou C, Adramerina A, Spyrou G, Tzanetis F.

Prague Med Rep. 2013;114(3):180-5.

PMID:
24093819
35.

How accurate are diagnostic tools for Epstein-Barr virus (EBV) to establish causal association of an uncommon clinical condition with EBV?

Neocleous C, Adramerina A, Spanou C, Spyrou G, Mitsios A, Dragoumi M, Tzanetis F.

Acta Virol. 2013;57(3):283-91. Review.

PMID:
24020753
36.

A Monte Carlo study of the influence of focal spot size, intensity distribution, breast thickness and magnification on spatial resolution of an a-Se digital mammography system using the generalized MTF.

Sakellaris T, Koutalonis M, Spyrou G, Pascoal A.

Phys Med. 2014 May;30(3):286-95. doi: 10.1016/j.ejmp.2013.08.002. Epub 2013 Sep 5.

PMID:
24011672
37.

BiDaS: a web-based Monte Carlo BioData Simulator based on sequence/feature characteristics.

Paraskevopoulou MD, Vlachos IS, Athanasiadis E, Spyrou G.

Nucleic Acids Res. 2013 Jul;41(Web Server issue):W582-6. doi: 10.1093/nar/gkt420. Epub 2013 May 28.

38.
39.

ChemBioServer: a web-based pipeline for filtering, clustering and visualization of chemical compounds used in drug discovery.

Athanasiadis E, Cournia Z, Spyrou G.

Bioinformatics. 2012 Nov 15;28(22):3002-3. doi: 10.1093/bioinformatics/bts551. Epub 2012 Sep 8.

PMID:
22962344
40.

Endoplasmic reticulum stress and mineralization inhibition mechanism by the resinous monomer HEMA.

Diamanti E, Mathieu S, Jeanneau C, Kitraki E, Panopoulos P, Spyrou G, About I.

Int Endod J. 2013 Feb;46(2):160-8. doi: 10.1111/j.1365-2591.2012.02103.x. Epub 2012 Aug 13.

PMID:
22889382
41.

The psycho-social impact of facial skin cancers.

Caddick J, Green L, Stephenson J, Spyrou G.

J Plast Reconstr Aesthet Surg. 2012 Sep;65(9):e257-9. doi: 10.1016/j.bjps.2012.02.022. Epub 2012 Mar 21. No abstract available.

PMID:
22440740
42.

Comprehensive field synopsis and systematic meta-analyses of genetic association studies in cutaneous melanoma.

Chatzinasiou F, Lill CM, Kypreou K, Stefanaki I, Nicolaou V, Spyrou G, Evangelou E, Roehr JT, Kodela E, Katsambas A, Tsao H, Ioannidis JP, Bertram L, Stratigos AJ.

J Natl Cancer Inst. 2011 Aug 17;103(16):1227-35. doi: 10.1093/jnci/djr219. Epub 2011 Jun 21. Review.

43.

PepServe: a web server for peptide analysis, clustering and visualization.

Alexandridou A, Dovrolis N, Tsangaris GT, Nikita K, Spyrou G.

Nucleic Acids Res. 2011 Jul;39(Web Server issue):W381-4. doi: 10.1093/nar/gkr318. Epub 2011 May 13.

44.

Bioinformatics approaches in the discovery and understanding of reproduction-related biomarkers.

Anagnostopoulos AK, Tsiliki G, Spyrou G, Tsangaris GT.

Expert Rev Proteomics. 2011 Apr;8(2):187-95. doi: 10.1586/epr.11.12. Review.

PMID:
21501012
45.

Osteophyte-induced rupture of a scalp tissue expander.

Wallis KL, Gurusinghe AD, Anwar MU, Spyrou G.

Ann Plast Surg. 2011 Dec;67(6):606-7. doi: 10.1097/SAP.0b013e31820eb52b.

PMID:
21467909
46.

Investigating the minimum required number of genes for the classification of neuromuscular disease microarray data.

Sakellariou A, Sanoudou D, Spyrou G.

IEEE Trans Inf Technol Biomed. 2011 May;15(3):349-55. doi: 10.1109/TITB.2011.2130531. Epub 2011 Mar 22.

PMID:
21427026
47.

Glutaredoxin-1 regulates TRAF6 activation and the IL-1 receptor/TLR4 signalling.

Chantzoura E, Prinarakis E, Panagopoulos D, Mosialos G, Spyrou G.

Biochem Biophys Res Commun. 2010 Dec 17;403(3-4):335-9. doi: 10.1016/j.bbrc.2010.11.029. Epub 2010 Nov 13.

PMID:
21078302
48.

Downgrading BIRADS 3 to BIRADS 2 category using a computer-aided microcalcification analysis and risk assessment system for early breast cancer.

Giannakopoulou G, Spyrou GM, Antaraki A, Andreadis I, Koulocheri D, Zagouri F, Nonni A, Filippakis GM, Nikita KS, Ligomenides PA, Zografos GC.

Comput Biol Med. 2010 Nov-Dec;40(11-12):853-9. doi: 10.1016/j.compbiomed.2010.09.005. Epub 2010 Oct 14.

PMID:
20950798
49.

A two-dimensional proteomic profile of Tetrahymena thermophila whole cell lysate.

Xanthopoulou AG, Anagnostopoulos D, Vougas K, Anagnostopoulos AK, Alexandridou A, Spyrou G, Siafaka-Kapadai A, Tsangaris GT.

In Vivo. 2010 Jul-Aug;24(4):443-56.

PMID:
20668310
50.

Can electronic zoom replace magnification in mammography? A comparative Monte Carlo study.

Koutalonis M, Delis H, Pascoal A, Spyrou G, Costaridou L, Panayiotakis G.

Br J Radiol. 2010 Jul;83(991):569-77. doi: 10.1259/bjr/21753020.

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